Christoph Schaniel, PhD¹, Shivani Handa, MD^2,3*, Joseph Tripodi, PhD⁴, MD Babu Mia^5*, Christian Salib, MD^6*, Jeff Vierstra, PhD^7*, Allison J Cote, PhD^7*, Daiva Ahire, MS^8*, Douglas Tremblay, MD⁹, Bridget Kelly Marcellino, MD, PhD¹⁰, John A Stamatoyannopoulos, MD^7*, Vesna Najfeld, PhD^4,9 and Ronald Hoffman, MD¹

¹The Tisch Cancer Institute, Division of Hematology & Oncology, Icahn School of Medicine at Mount Sinai, New York, NY
²Division of Hematology & Oncology, Department of Medicine, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY
³Division of Hematology, The Ohio State University Wexner Medical Center, Columbus, OH
⁴Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY
⁵The Tisch Cancer Institute, Division of Hematology&Oncology, Icahn School of Medicine at Mount Sinai, New York, NY
⁶Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY
⁷Altius Institute for Biomedical Sciences, Seattle, WA
⁸Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, NEW YORK, NY
⁹Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY
¹⁰Division of Hematology & Oncology, Icahn School of Medicine at Mount Sinai, New York, NY

Helene Pasquer^1*, Valeria Bisio^2*, Antoine Forget^3*, Maxime Battistella^4*, Barouyr Baroudjian^5*, Raphael Marie^1*, Emmanuelle Latour^1*, Cecile Culeux^1*, Lea Pelissier^1*, Blandine Roux^1*, Khansa Saadallah^1*, Matthieu Duchmann, MD, PhD^6*, Thierry Tchenio^1*, Abdellah Tebani^7*, Amandine Gouverneur^8*, Fanelie Jouenne^9*, Jerome Lambert^10*, Isabelle Madelaine^11*, Lionel Ades, MD, PhD¹², Emmanuel Raffoux, MD^13*, Pernelle Noize^8*, Bruno Cassinat^14,15, Soumeya Bekri^7*, Juliette Soret-Dulphy^16*, Samia Mourah^9*, Camille Lobry^1*, Alexandre Puissant, PhD¹, Jean-Jacques Kiladjian, MD, PhD^16,17, Nicolas Dulphy^2*, Celeste Lebbe^5* and Lina Benajiba, MD, PhD^1,16

¹INSERM UMR944, Saint-Louis Research Institut, Paris, France
²INSERM UMR 1160, Saint-Louis Research Institut, Paris, France
³Department of Cellular and Molecular Pharmacology (UCSF), Nevan Krogan's lab, San Francisco, CA
⁴Department of Pathology, Saint-Louis Hospital, Paris, France
⁵Dermatology department, Saint-Louis Hospital, Paris, France
⁶Unité 944/7212-GenCellDi, Saint-Louis Research Institute, INSERM, CNRS, Université Paris Cité, Paris, France
⁷Department of Metabolic Biochemistry, Rouen University Hospital, Rouen, France
⁸Department of clinical pharmacology, Bordeaux University Hospital, Bordeaux, France
⁹Department of Tumor Genomics and Pharmacology, Saint-Louis Hospital, Paris, France
¹⁰Biostatistics Department, Saint-Louis Hospital, Paris, France
¹¹Pharmacy department, Saint-Louis Hospital, APHP, Paris, France
¹²Service d'Hématologie Séniors, Saint-Louis Hospital, Paris, France
¹³Hematology Department, Saint Louis Hospital, Paris, France
¹⁴INSERM UMR 1131, Saint-Louis Research Institut, Paris, France
¹⁵Cellular biology departement, Saint-Louis Hospital, Paris, France
¹⁶Clinical Investigation Center, Saint-Louis Hospital, Paris, France
¹⁷Hopital Saint-Louis, Paris, France

Jovana Rajak^1,2,3,4*, Ke Meng^2,5*, Anna Lena Stippel^1*, Jun Wang^1,2,4*, Naile Koleci^1,2*, Alexandra Emilia Schlaak^5*, Hui Xiao^1,2,4*, Christian Flotho, MD^1,6,7*, Charlotte Marie Niemeyer, MD^1,6,7, Bertram Bengsch^5,6,7* and Miriam Erlacher^1,4,6,7

¹Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, University Medical Center Freiburg, Freiburg, Germany
²Faculty of Biology, University of Freiburg, Freiburg, Germany
³Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, Freiburg, Germany
⁴Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany
⁵Clinic for Internal Medicine II, University Medical Center Freiburg, Freiburg, Germany
⁶The German Cancer Consortium (DKTK), Heidelberg, Germany
⁷German Cancer Research Center (DKFZ), Heidelberg, Germany

Takuma Ohashi, PhD^1*, Hiroyoshi Kunimoto, PhD¹, Akiko Adachi^1*, Ayaka Miura, BS^1*, Takayuki Sakuma, MD^1*, Junji Ikeda, MD^1*, Yoko Ino^2*, Jotaro Harada, MD^3*, Yuko Shimosato, MD^4*, Keita Yamamoto^4*, Yayoi Kimura^2*, Susumu Goyama, MD PhD^4*, Satoshi Fujii^3*, Tomohiko Tamura, MD, PhD⁵, Hiroaki Honda^6*, Sheng F. Cai, MD, PhD^7* and Hideaki Nakajima, MD, PhD¹

¹Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, Yokohama, Japan
²Advanced Medical Research Center, Yokohama City University, Yokohama, Japan
³Department of Molecular Pathology, Yokohama City University Graduate School of Medicine, Yokohama, Japan
⁴Division of Molecular Oncology, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, Tokyo University, Tokyo, Japan
⁵Department of Immunology, Yokohama City University Graduate School of Medicine, Yokohama, Japan
⁶Institute of Laboratory Animals, Tokyo Women’s Medical University, Tokyo, Japan
⁷Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY

Jimena Castorena^1,2*, Christophe Desterke, PhD^3,4*, Barbara Burroni, MD^5*, Lise Willems^6*, Marie-Caroline Le Bousse-Kerdilès, PhD^1,2*, Laurence Legros, MD, PhD^1,2,7* and Laura Velazquez, PhD^1,2*

¹INSERM UMRS-MD1197, Hôpital Paul Brousse, Villejuif, France
²Université Paris Saclay, Gif-sur-Yvette, France
³UMRS1310 INSERM, Hôpital Paul-Brousse, Villejuif, FRA
⁴Faculty of Medicine, University Paris Saclay, Le Kremlin Bicetre, France
⁵Department of Pathology, Hôpital Cochin, Université de Paris, APHP, Paris, France
⁶Service d'hématologie clinique, Hôpital Cochin, Université de Paris, APHP, Paris, France
⁷Service d’Hématologie-Clinique Ambulatoire (SHCA), APHP, Hôpital Bicêtre, Le Kremlin-Bicêtre, France

Indu Raman, MBBS^1,2*, Cavan Bennett, PhD^1*, Surender Juneja, MD³, Costas K. Yannakou, MBBS, PhD^2*, Tishya Indran, MBBS^1,3* and Sant-Rayn Pasricha, MD, PhD^1,3

¹Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia
²Molecular Oncology and Cancer Immunology, Epworth Healthcare, Melbourne, Australia
³Royal Melbourne Hospital, Melbourne, Australia

Diego A Pereira-Martins, PhD^1*, Antonio Bruno Alves-Silva, MSc^2*, Manuela Albuquerque De Melo, MSc^2*, Natasha Peixoto Fonseca, MSc^2*, Isabel Weinhäuser, PhD^1*, Fabio Augusto Bueno Perez, BSc^2*, Artur Bernardo Ribeiro Bellomi, BSc^2*, Lorena Lobo Figueiredo-Pontes, MD, PhD², João Agostinho Machado-Neto, PhD^3*, Lynn Quek, MD, Ph.D.^4*, Prodromos Chatzikyriakou, Ph.D.^4*, Gerwin A. Huls, Prof.¹, Emanuele Ammatuna, MD, PhD^1*, Jan Jacob Schuringa, Prof. Dr.¹ and Fabiola Traina, MD, PhD²

¹Department of Experimental Hematology, University Medical Center Groningen, Groningen, Netherlands
²Department of Medical Images, Hematology, and Oncology, University of São Paulo at Ribeirão Peto Medical School, Ribeirão Preto, Brazil
³Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil
⁴Myeloid Leukaemia Genomics and Biology Group, School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom

Karl Kapahnke^1,2*, Tabea Klaus, M.Sc.^1*, Manoj Gupta, PhD^1*, Disha Anand, M.Sc.^1*, Tamer Onder, PhD^3*, Tina M Schnoeder, PhD^4*, Florian H. Heidel, MD^5,6,7 and Florian Perner, MD¹

¹Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School (MHH), Hannover, Germany
²University Medicine Greifswald, Greifswald, Germany
³Koc University, School of Medicine, Istambul, Turkey
⁴Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School (MHH), Hannover, Germany
⁵Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany
⁶Leibniz Institute on Aging, Fritz-Lipmann-Institute, Jena, Germany
⁷Cellular Therapy Center (CTC), Hannover Medical School (MHH), Hannover, Germany

Joseph Tripodi, PhD¹, Shivani Handa, MD², Christoph Schaniel, PhD³, Daiva Ahire, MS^4*, Ronald Hoffman, MD⁵ and Vesna Najfeld, PhD^6,7

¹Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, Old Tappan, NJ
²Division of Hematology & Medical Oncology, Tisch Cancer Institute/ Icahn School of Medicine at Mount Sinai, New York, NY
³The Tisch Cancer Institute, Division of Hematology & Oncology, Icahn School of Medicine at Mount Sinai, New York, NY
⁴Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, NEW YORK, NY
⁵Tisch Cancer Institute, Department of Medicine, Division of Hematology/Oncology, Myeloproliferative Neoplasm-Research Consortium, Icahn School of Medicine at Mount Sinai, New York, NY
⁶Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY
⁷Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY

Vikas Bhuria, PhD^1,2,3, Martin Böttcher^1,2*, Vanja Zeremski^1*, Andreas Müller^2,3,4*, Dimitrios Mougiakakos, MD^1,2,3 and Thomas Fischer^1,2,3

¹Department of Hematology, Oncology and Cell Therapy, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany
²Health-Campus Immunology, Infectiology, and Inflammation (GC-I3), Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany
³Center for Health and Medical Prevention – CHaMP, Otto-von-Guericke University, Magdeburg, Germany
⁴Institute for Molecular and Clinical Immunology, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany

Jyoti Naik, PhD^1*, Haoxiao Zuo, PhD^1*, Jorn Kaspers, MSc^1*, Alex Karlsson-Parra, MD, PhD^1*, Jeroen Rovers, MD, PhD^1*, Bjorn T. Gjertsen, MD^2,3,4 and Satwinder Kaur Singh, PhD^5*

¹Mendus AB, Stockholm, Sweden
²Center for Cancer Biomarkers CCBIO, Department of Clinical Science, University of Bergen, Bergen, Norway
³KG Jebsen Centre for Myeloid Blood Cancer CMYC, University of Bergen, Bergen, Norway
⁴Department of Medicine, Hematology section, Haukeland University Hospital, Bergen, Norway
⁵Mendus AB, Stockholm, AL, Netherlands

Komei Nishimura^1,2*, Yuka Sugimoto, MD, PhD³, Keiki Nagaharu, MD, PhD^4*, Ryoichi Ono, MD, PhD^5*, Takuya Tsuji^6*, Akihide Nakamura, MD, PhD^4,5*, Eiko Ohya, MD^2,4*, Isao Tawara, MD, PhD⁴, Tetsuya Nosaka, MD, PhD^5* and Kohshi Ohishi, MD, PhD⁷

¹Department of Hematology and Oncology, Mie University Graduate School of Medicine, Tsu-City, Japan
²Department of Hematology, Matsusaka Chuo General Hospital, Matsusaka, Japan
³Department of Hematology and Oncology, Mie University, Tsu City, Mie Prefecture, Japan
⁴Department of Hematology and Oncology, Mie University Graduate School of Medicine, Tsu, Japan
⁵Department of Microbiology and Molecular Genetics, Mie University Graduate School of Medicine, Tsu, Japan
⁶Faculty of Medicine, Mie University, Tsu, Japan
⁷Transfusion Medicine and Cell Therapy, Mie University Hospital, Tsu, Japan

Freja Ekman, BSc, MPhil^1,2*, Sridhar Selvaraj, PhD^2*, Jason Gotlib, MD^3*, M. Kyle Cromer, PhD, MPhil, BS^4,5,6 and Matthew H. Porteus, MD, PhD^2*

¹Department of Genetics, Stanford University, Palo Alto, CA
²Department of Pediatrics, Stanford University, Stanford, CA
³Division of Hematology, Stanford Cancer Institute/ Stanford University School of Medicine, Stanford, CA
⁴Department of Surgery, University of California, San Francisco, San Francisco, CA
⁵Eli & Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA
⁶Department of Bioengineering & Therapeutic Sciences, University of California, San Francisco, San Francisco, CA

Hatem A. Ellaithy, MD^1*, Valentina Nardi, MD^2*, Harrison K. Tsai, MD, PhD^3*, Carmen Da Silva^1*, Peter G. Miller, MD, PhD⁴ and Gabriela S. Hobbs, MD⁵

¹Massachussetts General Hospital, Boston, MA
²Pathology Division, Harvard Medical School, Boston, MA
³Department of Pathology, Brigham and Women's Hospital, Boston, MA
⁴Massachusetts General Hospital, Boston
⁵Massachusetts General Hospital, Boston, MA