Parthiv V Sheth, MD¹, Michael Glenzer, MPH¹, Isaac Nwi-Mozu, PhD^1*, Peter Aguero, DPT, RMSK^1*, Bruno U.K. Steiner, DPT, RMSK^2*, Cindy Bailey, DPT^3*, Doris V. Quon, MD, PhD³, Rebecca Kruse-Jarres⁴ and Annette von Drygalski, MD, PharmD, RMSK¹

¹Center for Bleeding and Clotting Disorders, University of California San Diego, San Diego, CA
²Washington Center for Bleeding Disorders, Seattle, WA
³Orthopaedic Institute for Children, Orthopaedic Hemophilia Treatment Center, Los Angeles, CA
⁴Washington Center for Bleeding Disorders, University of Washington, Seattle, WA

Chia-Yau Chang^1,2,3*, Shiue-Wei Lai, MD, PhD^4,5*, Mei-Mei Cheng, MD^6*, Yen-Lin Liu, M.D., PhD^2,3,7*, Jia-Ruey Tsai, MD^3,8*, Chen-Hua Tsai, MD^3,9*, Wan-Ling Ho, MD, PhD^2,7*, Chao-Neng CHENG, MD^10*, Shu-Hsia Hu, MS^5,11* and Yeu-Chin Chen, MD^4,12

¹Department of Pediatrics, School of Medicine, College of Medicine, Taipei Medical University, Taipei City, Taiwan
²Division of Pediatric Hematology/Oncology, Department of Pediatrics, Taipei Medical University Hospital, Taipei, Taiwan
³Hemophilia Center, Taipei Medical University Hospital, Taipei, Taiwan
⁴Division of Hematology/Oncology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan
⁵Hemophilia Care and Research Center, Tri-Service General Hospital, Taipei, Taiwan
⁶Department of Pediatrics, Cheng Hsin General Hospital, Taipei, Taiwan
⁷Department of Pediatrics, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
⁸Department of Internal Medicine, Division of Hematology/Oncology, Taipei Medical University Hospital, Taipei, TWN
⁹Department of Internal Medicine, Division of Hematology/Oncology, Cheng Hsin General Hospital, Taipei, Taiwan
¹⁰Division of Pediatric Hematology/Oncology, Department of Pediatrics, National Cheng Kung University Hospital, Tainan, TWN
¹¹Hemophilia center, Taipei Medical University Hospital, Taipei, Taiwan
¹²Hemophilia Care & Research Center, Tri-Service General Hospital (TSGH), Taipei, Taipei (City), Taiwan

Jonathan C. Roberts, MD^1,2, Angela C Weyand, MD³, Mark T Reding, MD⁴, Nana Kragh, MSc^5*, Nicole Tsao, MS, PhD^6*, Emily Cibelli, PhD^7*, Gillian Hanson, ND^7*, Duygu Bozkaya^6* and Anne-Laure Tardy^8*

¹Bleeding & Clotting Disorders Institute, Dills Family Foundation Center for Research at BCDI, Peoria, IL
²Departments of Pediatrics and Medicine, University of Illinois College of Medicine, Peoria, IL
³University of Michigan Medical School, Ann Arbor, MI
⁴Center for Bleeding and Clotting Disorders, University of Minnesota Medical Center, Minneapolis, MN
⁵Sobi, Stockholm, Sweden
⁶Sanofi, Cambridge, MA
⁷PicnicHealth, San Francisco, CA
⁸Sanofi, Gentilly, Paris, France

Mark T Reding, MD¹, María Teresa Alvarez-Román, PhD, MD^2*, Giancarlo Castaman^3*, Maissaa Janbain, MD^4*, Tadashi Matsushita, MD⁵, Karina Meijer, MD, PhD^6*, Kathrin Schmidt, MD^7* and Johannes Oldenburg, MD⁸

¹Center for Bleeding and Clotting Disorders, University of Minnesota Medical Center, Minneapolis, MN
²Thrombosis and Haemostasis Unit, Hospital Universitario La Paz, Madrid, Spain
³Department of Oncology, Center for Bleeding Disorders and Coagulation, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy
⁴Deming Department of Internal Medicine, Section of Hematology and Medical Oncology, Tulane School of Medicine, New Orleans, LA
⁵Nagoya University Hospital, Nagoya, Japan
⁶Department of Hematology, University Medical Center Groningen, Groningen, Netherlands
⁷OS Operations, Bayer, Berlin, Germany
⁸Institute for Experimental Hematology and Transfusion Medicine, University Hospital Bonn, Bonn, Germany

Kasey Boynton^1*, Monique Adams^1*, Karin Knobe^2*, Steven Farfan^1* and Isaac Darkwah^1*

¹Sanofi, New Jersey
²Sanofi, Massachusetts

Susan Halimeh, MD^1,2, Mohamad Ayman Daoud^3*, Derya Schmitz, derya.schmitz@gzrr.de^4* and Bjoern Habermann^5*

¹Königstrasse 13, Gerinnungszentrum rhein ruhr, Duisburg, Germany
²Hemophilia and Thrombosis Treatment Center, Essen, Germany
³Hematology research center GmbH, Duisburg
⁴Gerinnungszentrum Rhein-Ruhr, Duisburg, Germany
⁵Praxis Orthopaedie am Fuerstenhof, Frankfurt, Germany

Qianqian Mao, MBBS^1*, Zhengping Li, MBBS^1*, Qixaun Yin^2*, Gang Li^3*, Zhenping Chen, PhD, MD^3* and Runhui Wu, MD⁴

¹Haemophilia Comprehensive Care Center, Hematology Center, Beijing Key Laboratory of Pediatric Hematology Oncology; National Key Discipline of Pediatrics (Capital Medical University); Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, China
²Haemophilia Comprehensive Care Center, Hematology Center, Beijing Key Laboratory of Pediatric Hematology Oncology; National Key Discipline of Pediatrics (Capital Medical University); Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, AL, China
³Haematologic Disease Laboratory, Hematology Center, Beijing Key Laboratory of Pediatric Hematology Oncology; National Key Discipline of Pediatrics (Capital Medical University); Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing Pediatric Research Institute, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, China
⁴Hematology Department, Beijing Children's Hospital, Affiliated to Capital Medical University, Beijing, China

Tyler W. Buckner, MD, MSc¹, Craig Kessler, MD², Giancarlo Castaman^3*, Cédric Hermans^4*, Victor Jimenez-Yuste, MD, PhD^5*, Johnny Mahlangu^6*, Wolfgang A. Miesbach, MD, PhD^7*, Johannes Oldenburg, MD⁸, Michael Recht, MD, PhD, MBA⁹, Leonard A. Valentino, MD¹⁰, Allison P Wheeler, MD/MSCI¹¹ and Steven W. Pipe, MD¹²

¹Hemophilia and Thrombosis Center, University of Colorado School of Medicine, Aurora, CO
²Lombardi Comprehensive Cancer Center, MedStar Georgetown University Hospital, Washington, DC
³Center for Bleeding Disorders, Department of Oncology, Careggi University Hospital, Florence, Italy
⁴Cliniques Saint-Luc, Université Catholique de Louvain, Brussels, Belgium
⁵Hospital Universitario La Paz, Madrid, Spain
⁶Hemophilia Comprehensive Care Center, University of the Witwatersrand and National Health Laboratory Service, Johannesburg, South Africa
⁷Goethe University Hospital, Frankfurt, Germany
⁸Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn AöR, Medical Faculty, University of Bonn, Bonn, Germany
⁹Yale Center for Bleeding and Clotting Disorders, Yale University School of Medicine, New Haven, CT
¹⁰Rush University Medical Center, Chicago, IL
¹¹Washington Center for Bleeding Disorders, Division of Pediatric Hematology/Oncology & Division of Hematology and Oncology, University of Washington School of Medicine, Seattle, WA
¹²University of Michigan, Ann Arbor, MI

Lynn Malec, MD, MSc¹, Davide Matino, MD, MSc^2*, Kieran Wynne-Cattanach, MSc^3*, Chris Blazos, BSc^3*, Duygu Bozkaya^4*, Anne-Laure Tardy^5*, Sylvie Bozzi, MS^6* and Jennifer Dumont⁴

¹Comprehensive Center for Bleeding Disorders, Versiti Blood Center of Wisconsin, Wisconsin
²McMaster University, Hamilton, ON, Canada
³Adelphi Real World, Bollington, United Kingdom
⁴Sanofi, Cambridge, MA
⁵Sanofi, Gentilly, Paris, France
⁶Sanofi, Gentilly, France

Susan Halimeh, MD^1,2, Mohamad Ayman Daoud^3*, Derya Schmitz, derya.schmitz@gzrr.de^4* and Bjoern Habermann^5*

¹Königstrasse 13, Gerinnungszentrum rhein ruhr, Duisburg, Germany
²Hemophilia and Thrombosis Treatment Center, Essen, Germany
³Hematology research center GmbH, Duisburg
⁴Gerinnungszentrum Rhein-Ruhr, Duisburg, Germany
⁵Praxis Orthopaedie am Fuerstenhof, Frankfurt, Germany

Mariasanta Napolitano, MD, PhD^1,2, Marta Mattana^3*, Simona Raso, MD^4*, Claudia Cammarata, MD^5*, Manuela Giuseppa Ingrascì, MD^6*, Riccardo Tomasello, MD^7*, Sergio Siragusa, MD, PhD⁸, Marzia Leotta, MD^9*, Alessandra Strangio, MD^9*, Antonella Ierardi, MD^9* and Rita Carlotta Santoro, MD^10*

¹Department of Health Promotion, Mother and Child Care, Internal Medicine and Med, Palermo, ITA
²University of Palermo, Palermo, ITA
³Department of precision medicine in medical, surgical and critical care (Me.Pre.Cc), University of Palermo, Raffadali, Italy
⁴Department of Hematology and Rare Diseases, Azienda Ospedaliera Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy
⁵Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (ProMISE), University of Palermo, Palermo, Italy
⁶Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (ProMISE),, University of Palermo, Palermo, Italy
⁷University of Palermo, Palermo, Italy
⁸Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), Università di Palermo, Palermo, Italy
⁹Azienda Ospedaliero Universitaria Renato Dulbecco, Haemostasis and Thrombosis Unit Dpt Haemato-Oncology, Catanzaro, Italy
¹⁰Hemostasis and Thrombosis Unit, Azienda Ospedaliera Pugliese-Ciaccio, 88100 Catanzaro, Italy., Catanzaro, ITA

Saad Ahmed, MD, FRCPath^1,2, Mary Kavanagh^3*, Imelda Kelly^3*, Caitriona Ferry^3*, Bertille Mullen^3*, Bridin Brady^3*, Ruth Hunter Nolan^3* and Beatrice Nolan, FRCPath, MB^2,3*

¹Paediatrics Coagulation Centre, Children's Health Ireland at Crumlin, Dublin, Dublin, Ireland
²School of Medicine, Paediatrics Department, Trinity College Dublin, Dublin, Ireland
³Paediatrics Coagulation Centre, Children's Health Ireland at Crumlin, Dublin, Ireland