Jenna A. Fernandez, PhD¹, Yael Kusne, MD, PhD², Fernanda Gutierrez-Rodrigues, PhD³, Bhavisha A. Patel, MD³, Christy Finke, BS^1*, Emma M. Groarke, MD³, Matthew J Koster, M.D.^4*, Abhishek A. Mangaonkar, MBBS⁵, Naseema Gangat, MBBS¹, Kenneth Warrington^6*, Kaaren K. Reichard, MD⁷, Horatiu Olteanu, M.D., Ph.D.⁸, David Viswanatha, MD⁹, Rong He, MD¹⁰, Megan Sullivan, M.D.^11*, Kambiz Kalantari, M.D.^12*, Alexander Hines, M.D.^13*, Daniel Montes, M.D.^6*, Neal S. Young, MD³, David B Beck, MD, PhD^14,15*, Wazim Ismail Mohammed, Ph.D.^16*, Alexandre Gaspar-Maia, PhD^5*, Terra L. Lasho, PhD¹ and Mrinal M. Patnaik, MD, MBBS¹⁷

¹Division of Hematology, Mayo Clinic, Rochester, MN
²Mayo Clinic, Phoenix, AZ
³Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
⁴Division of Rheumatology, Mayo Clinic, Rochester, MN
⁵Mayo Clinic, Rochester, MN
⁶Division of Rheumatology, Department of Internal Medicine, Mayo Clinic, Rochester, MN
⁷Department of Pathology, Mayo Clinic, Rochester, MN
⁸Division of Hematopathology, Mayo Clinic, Rochester, MN
⁹Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester
¹⁰Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
¹¹Division of Rheumatology, Department of Internal Medicine, Mayo Clinic, Phoenix, AZ
¹²Division of Nephrology & Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN
¹³Division of Dermatology, Department of Internal Medicine, Mayo Clinic, Rochester, MN
¹⁴Division of Rheumatology, Department of Medicine, NYU Grossman School of Medicine, New York
¹⁵Center for Human Genetics and Genomics, NYU Grossman School of Medicine, New York, NY
¹⁶Experimental Pathology and Laboratory Medicine, Mayo Clinic, Rochester, MN
¹⁷Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN

Alexander Röth, MD¹, Guangsheng He^2*, Andres Brodsky^3*, Chatree Chai-Adisaksopha, M.D., Ph.D.^4*, Narcisa Sonia Comia^5*, Anna Gaya^6*, Martin Höglund, MD, PhD⁷, Richard J. Kelly, MBChB, PhD^8*, Ahlam Naila Kori, MD^9*, Je-Hwan Lee^10*, Naoshi Obara, MD, PhD^11*, Antonio M Risitano, MD, PhD¹², Anita Appius, PhD^13*, Leigh Beveridge^14*, Brittany Gentile, PhD^14*, Zilu Zhang^15*, Bing Han^16* and Sasha Sreckovic, MD^17*

¹Department of Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany
²Jiangsu Province Hospital, Nanjing, China
³Hematology Division, Hospital de Clinicas “José de San Martín”, University of Buenos Aires, and Organizacion Medica de Investigacion (OMI), Buenos Aires, Argentina
⁴Division of Hematology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
⁵Research Center, Mary Mediatrix Medical Center, Lipa, Philippines
⁶Hematology Department, Hospital Clinic Barcelona, Barcelona, Spain
⁷Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden
⁸Department of Haematology, St. James’s University Hospital, Leeds, United Kingdom
⁹Department of Haematology, Hospital Tengku Ampuan Afzan, Kuantan, Malaysia
¹⁰Department of Hematology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea, Republic of (South)
¹¹Department of Hematology, University of Tsukuba Hospital, Tsukuba, Japan
¹²Hematology and BMT Unit, AORN San Giuseppe Moscati, Avellino, Italy
¹³F. Hoffmann-La Roche Ltd, Basel, Switzerland
¹⁴Genentech, Inc., South San Francisco, CA
¹⁵Roche Product Development, Shanghai, China
¹⁶Department of Hematology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Peking, China
¹⁷Genentech, Inc, South San Francisco

Fengkui Zhang^1*, Bing Han^2*, Li Zhang^3* and Xin Zhao⁴

¹State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology Blood Diseases Hospital, Chinese Academy of Medical Sciences Peking Union Medical College, Tianjin, China
²Department of Hematology, Chinese Academy of Medical Sciences, Peking Union Medical College Hospital, Beijing, China
³State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology&Blood Diseases Hospital, Chinese Academy of Medical Sciences&Peking Union Medical College, Tianjin, China
⁴State Key Laboratory of Experimental Hematology,National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China

Ken Ishiyama, MD, PhD^1,2, Ritsuro Suzuki, MD, PhD³, Kinuko Mitani, MD, PhD^4*, Hiroyuki Maruyama, MD, PhD^5*, Yasushi Onishi, MD, PhD^6*, Kensuke Usuki, MD, PhD⁷, Hideo Koh, MD, PhD^8,9*, Katsuto Takenaka, MD, PhD¹⁰, Seishi Ogawa, MD, PhD¹¹, Kana Matsumoto, PhD^12*, Takuto Takahashi, MD, PhD^13*, Kazuyoshi Hosomichi, PhD^14*, Yoshitaka Zaimoku, MD, PhD¹⁵, Fumiaki Kiyomi, PhD^16*, Itaru Matsumura, MD¹⁷, Koichi Akashi, MD, PhD^18* and Shinji Nakao, MD, PhD^15,19

¹Department of Hematology, National Center for Global Health and Medicine, Tokyo, Japan
²Department of Hematology, Kanazawa University Hospital, Kanazawa, Ishikawa, Japan
³Division of Hematology and Oncology, Department of Internal Medicine, Faculty of Medicine, Shimane University, Izumo, Japan
⁴Dokkyo Univ. School of Med., Tochigi, JPN
⁵Kanazawa University Graduate School of Medical Science, Kanazawa-Shi, JPN
⁶Department of Hematology, Tohoku University Hospital, Sendai, Japan
⁷NTT Medical Center Tokyo, Tokyo, Japan
⁸Department of Preventive Medicine and Environmental Health, Osaka Metropolitan University Graduate School of Medicine, Osaka, JPN
⁹Department of Hematology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan
¹⁰Department of Hematology, Clinical Immunology and Infectious Diseases, Ehime University Graduate School of Medicine, Toon, Japan
¹¹Kyoto University, Sakyoku, KYO, Japan
¹²Department of Clinical Pharmaceutics, Faculty of Pharmaceutical Sciences,, Doshisha Women’s College of Liberal Arts, Kyotanabe, Japan
¹³Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, Boston, MA
¹⁴Laboratory of Computational Genomics, School of Life Science, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan
¹⁵Department of Hematology, Kanazawa University, Kanazawa, Japan
¹⁶Clinical Research Support Center Kyushu, Clinical Research Support Center Kyushu, Fukuoka, Japan
¹⁷Department of Hematology and Rheumatology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan
¹⁸Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
¹⁹Japanese Red Cross Ishikawa Blood Center, Kanazawa, Japan

Carmelo Gurnari, MD, PhD^1,2, Elisa Galossi^1*, Eleonora Lumia^1*, Alfonso Piciocchi^3*, Mariadomenica Divona^1*, Tiziana Ottone^1*, Elisa Casciani^1*, Francesca Romano^1*, Elisa Diral, MD^4*, Alessandro Tomelleri, MD^5*, Federico Caroni^6*, Antonio Vitale^7*, Gregorio Maria Bergonzi, MD^4*, Annalisa Condorelli^8*, Giorgia Battipaglia, MD^9*, Erika Morsia^10*, Antonella Poloni, PhD^11*, Elena Crisa, MD^12*, Daniela Caravelli^12*, Paola Triggianese^1*, Arianna Savi, MD^13*, Chiara Cardamone, MD^14*, Matteo Dragani, MD^15*, Giulia Rivoli, MD^15*, Federica Pilo, MD^16*, Davide Firinu^17*, Sara Plebani^18*, Francesco D'Agostino^19*, Alessandro D'Ambrosio, MD^20*, Katja Sockel, MD^21*, Antonio Curti, MD, PhD²², Cristina Papayannidis, MD, PhD²³, Marco Frigeni^8*, Attilio Olivieri^10*, Fabrizio Pane²⁴, Monica Bocchia, MD^6*, Luca Cantarini^7*, Alessandro Rambaldi²⁵, Corrado Campochiaro, MD^5*, Lorenzo Dagna, MD^26*, Raffaella Greco, MD^27*, Fabio Ciceri, MD^28*, Orietta Spinelli^8*, Christian Thiede, MD²¹ and Maria Teresa Voso, MD¹

¹Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
²Cleveland Clinic Foundation, Cleveland, OH
³GIMEMA Foundation, Rome, Italy
⁴Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute, Milan, Italy
⁵Unit of Immunology, Rheumatology, Allergy and Rare diseases, IRCCS San Raffaele Hospital, Milano, Italy
⁶Hematology, Azienda Ospedaliera Universitaria Senese, University of Siena, Siena, Italy
⁷Rheumatology Unit, Department of Medical Sciences, Surgery and Neurosciences, University of Siena and Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center, Siena, Italy
⁸Hematology and Bone Marrow Transplant Unit, ASST Papa Giovanni XXIII, Bergamo, Italy
⁹Federico II University of Naples, Hematology Department, Naples, Italy, Naples, Italy
¹⁰Clinica di Ematologia Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy
¹¹Hematology Unit, Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy
¹²Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy
¹³University of Turin, Department of Clinical and Biological Sciences, Turin, Italy
¹⁴Division of Allergy and Clinical Immunology, University of Salerno, Salerno, Italy
¹⁵Hematology and Cellular Therapy Division, IRCCS Ospedale Policlinico San Martino, Genova, Italy
¹⁶Hematology and BMT Unit, A.Businco hospital, AOB Cagliari, Italy, Cagliari, Italy
¹⁷Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy
¹⁸Hematology, San Salvatore Hospital, L'Aquila, Italy
¹⁹UOC Hematology, IRCCS Ospedale Casa Sollievo della sofferenza, San Giovanni Rotondo, Italy
²⁰AORN S.Anna e S. Sebastiano, Caserta, Italy
²¹University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany
²²Istituto di Ematologia "Seràgnoli", IRCCS Azienda Ospedaliero–Universitaria di Bologna, Bologna, Italy
²³IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia “Seràgnoli”, Bologna, Italy
²⁴Division of Hematology and SCT Unit, Federico II University, Naples, Naples, Italy
²⁵Department of Oncology-Hematology, Azienda Socio-Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Italy
²⁶Unit of Immunology, Rheumatology, Allergy and Rare diseases, IRCCS San Raffaele Hospital, Milan, Italy
²⁷Unit of Hematology and Stem Cell Transplantation, IRCCS San Raffaele Scientific Institute, Milan, Italy
²⁸Hematology and Bone Marrow Transplantation Unit, I.R.C.C.S. San Raffaele Scientific Institute, Milan, Italy

Talya Wittmann Dayagi, MD^1,2*, Laura Willis^3*, Catherine Corriveau-Bourque, MD⁴, Michaela Cada, MD, FRCPC, MPH^1,2*, Zora R. Rogers, MD⁵, Taizo A. Nakano, MD⁶, Timothy S. Olson, MD, PhD^7,8, Winfred C. Wang, MD⁹, Alfred Gillio, MD¹⁰, Thomas D. Coates, MD^11,12, Anjulika Chawla, MD, FAAP¹³, Paul Castillo, MD¹⁴, Peter Kurre, MD^7,8, Christopher Gamper, MD, PhD¹⁵, Staci D. Arnold, MD, MBA, MPH^16*, Sarita Joshi, MD, MBBS¹⁷, Amy E. Geddis, MD, PHD^18*, Jessica Boklan, MD, MPH¹⁹, Jennifer A. Rothman, MD²⁰, James N. Huang, MD²¹, Gary M. Kupfer, MD²², Bertil Glader, MD, PhD^23,24, Kelly J. Walkovich, MD²⁵, Alexis Thompson, MD, MPH^26,27, Rabi Hanna, MD²⁸, David A. Williams, MD^29,30, Akiko Shimamura, MD, PhD³¹ and Yigal Dror, MD, FRCPC^1,2,32,33

¹Department of Paediatrics, University of Toronto, Toronto, ON, Canada
²Marrow Failure and Myelodysplasia Program, Division of Haematology and Oncology, The Hospital for Sick Children, Toronto, ON, Canada
³Division of Haematology and Oncology, The Hospital for Sick Children, Toronto, Canada
⁴University of Alberta, Edmonton, AB, CAN
⁵Children's Medical Center Dallas Ctr. for Cancer & Blood Disorders, Dallas, TX
⁶Children's Hospital Colorado, Denver, CO
⁷Comprehensive Bone Marrow Failure Center, Children's Hospital of Philadelphia, Philadelphia, PA
⁸Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
⁹Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN
¹⁰Hackensack University Medical Center, Hackensack, NJ
¹¹Pediatrics and Pathology, University of Southern California Keck School of Medicine, Los Angeles, CA
¹²Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Los Angeles, CA
¹³bluebird bio, Inc., Somerville, MA
¹⁴Pediatric Hematology Oncology Division, UF Health Shands Children's Hospital, Gainesville, FL
¹⁵Johns Hopkins University School of Medicine, Baltimore, MD
¹⁶Aflac Canver and Blood Disorders Center at Children's Healthcare of Atlanta, Emory University, Atlanta
¹⁷Fortea Inc., Burlington, NC
¹⁸Cancer and Blood Disorders Center, Seattle Children's Hospital, Seattle, WA
¹⁹Department of Child Health, University of Arizona College of Medicine, Phoenix, AZ
²⁰Duke University Medical Center, Durham, NC
²¹UCSF Benioff Children's Hospital, San Francisco, CA
²²Georgetown University Medical Center, Washington, DC
²³Department of Pediatrics, Division of Hematology, Oncology, Stem Cell Transplantation, and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA
²⁴Lucile Packard Children’s Hospital, Palo Alto, CA
²⁵C.S. Mott Children’s Hospital, University of Michigan, Ann Arbor, MI
²⁶Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA
²⁷Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
²⁸Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
²⁹Pediatric Oncology, Dana Farber Cancer Institute, Boston, MA
³⁰Hematology/Oncology, Boston Children's Hospital, Boston, MA
³¹Boston Children's Hospital, Boston, MA
³²Genetics & Genome Biology Program, Research Institute, The Hospital for Sick Children, Toronto, ON, Canada
³³Institute of Medical Science, University of Toronto, Toronto, ON, Canada

Caroline Piatek, MD¹, Jong Wook Lee², Morag Griffin, MBChB, MRCP^3*, Jun-Ichi Nishimura⁴, Christopher Patriquin, MD, MSc, FRCPC⁵, Hubert Schrezenmeier, MD^6,7, Wilma Barcellini, MD^8*, Jamile Shammo, MD⁹, Anna Gaya^10*, Mohammed Mahdi^11*, Peng Liu^11*, Karl-Johan Myren^11*, Andrew Messali^11*, Flore Sicre de Fontbrune, MD^12*, Jens Panse, MD^13,14 and Austin G. Kulasekararaj, MD, MBBS, FRCPath, MRCP¹⁵

¹Jane Anne Nohl Division of Hematology and Center for the Study of Blood Diseases, USC Norris Comprehensive Cancer Center, Los Angeles, CA
²Hanyang University Seoul Hospital, Seoul, Korea, Republic of (South)
³Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
⁴Department of Hematology and Oncology, Osaka University Graduate School of Medicine, Osaka, Japan
⁵Division of Medical Oncology & Hematology, University Health Network, Toronto, ON, Canada
⁶Institute of Transfusion Medicine, University of Ulm, Ulm, Germany
⁷Institute of Clinical Transfusion Medicine and Immunogenetics Ulm, University Hospital of Ulm and German Red Cross Blood Service Baden-Württemberg-Hessen, Ulm, Germany
⁸Hematology Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
⁹Feinberg School of Medicine, Northwestern University, Chicago, IL
¹⁰Hospital Clínic de Barcelona, Barcelona, Spain
¹¹Alexion, AstraZeneca Rare Disease, Boston, MA
¹²Centre de Référence Aplasie Médullaire, Service d’Hématologie Greffe, Assistance Publique des Hôpitaux de Paris, Hôpital Saint-Louis, Paris, France
¹³Department of Oncology, Hematology, Hemostaseology and Stem Cell Transplantation, University Hospital RWTH Aachen, Aachen, Germany
¹⁴Center for Integrated Oncology, Aachen Bonne Cologne Düsseldorf (ABCD), Aachen, Germany
¹⁵King’s College Hospital-NHS Foundation Trust, NIHR/Wellcome King’s Clinical Research Facility, and King’s College London, London, United Kingdom

Jibran Durrani, MD¹, Leonard Chen^2*, Nuri Cha^3*, Zhijie Wu, MD, PhD^4*, Shouguo Gao, PhD^4*, Hiroki Mizumaki, MD^5*, Jennifer Lotter, ms⁴, Olga Rios^4*, Colin O. Wu, PhD^6*, Willy Albert Flegel, MD², Neal S. Young, MD⁴, Emma M. Groarke, MD⁴ and Bhavisha A. Patel, MD⁴

¹Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, BETHESDA, MD
²NIH, Bethesda, MD
³NIH Clinical Center, National Institutes of Health, Bethesda, MD
⁴Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
⁵Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Washington, MD
⁶Office of Biostatistics Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD

Hubert Schrezenmeier, MD^1,2, Mohammed Mahdi^3*, Christoph Gasteyger, MD^3* and Cecile De Coster^3*

¹Institute for Transfusion Medicine, Ulm University, Ulm, Germany
²Institute for Clinical Transfusion Medicine and Immunogenetics, German Red Cross Blood Transfusion Service Baden-Württemberg-Hessen and University Hospital Ulm, Ulm, Germany
³Alexion, AstraZeneca Rare Disease, Boston, MA

Munevver N. Duran, BA^1*, Zehra Tombul^1*, Mutlu Mete^2*, Ahmet Celal Toprak^3*, Olisaemeka Ogbue, MBBS⁴, Hussein Awada⁵, Carmelo Gurnari, MD, PhD⁶, Jaroslaw Maciejewski⁵, Ibrahim F. Ibrahim, MD⁷, Merve Ozturk^1*, Yusuf M. Ozcan^8*, Brielle Johnson^1*, Christine Ejiofor^1*, Alper Olcal^1* and Taha Bat⁷

¹UT Southwestern Medical Center, Dallas, TX
²Department of Information Science, University of North Texas, Denton, TX
³University of Texas Southwestern Medical Center, Dallas, TX
⁴Fairview Hospital, Cleveland Clinic Foundation, Rocky River, OH
⁵Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
⁶Cleveland Clinic Foundation, Cleveland, OH
⁷Department of Hematology and Oncology, University of Texas Southwestern Medical Center, Dallas, TX
⁸University of Texas Dallas, Richardson, TX

Derek Chan, MD, PhD^1,2, Meltem Omur, MS^3,4*, Diana Lin, MSc^5*, Wyeth Wasserman, PhD^3,4*, Aly Karsan, MD, FRCPC^5,6 and Suzanne Vercauteren, MD, PhD, FRCPC^6,7

¹The Hospital for Sick Children, Toronto, ON, Canada
²Division of Haematology/Oncology, Department of Paediatrics, University of Toronto, Toronto, ON, Canada
³Centre for Molecular Medicine and Therapeutics, British Columbia Children’s Hospital Research Institute, Vancouver, BC, Canada
⁴Department of Medical Genetics, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada
⁵Canada’s Michael Smith Genome Sciences Centre, BC Cancer Research Centre, Vancouver, BC, Canada
⁶Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada
⁷British Columbia Children’s Hospital Research Institute, Vancouver, BC, Canada

Weiwang Li^1,2,3*, Lele Zhang^1,2,3*, Hong Pan^1,2,4*, Zhen Gao^1,2,3*, Jianping Li^1,2,3*, Neng Nie^1,2,3*, Xin Zhao^1,2,3, Jinbo Huang^2,3,5*, Jingyu Zhao, MSc^1,2,3*, Xiao Yu^1,2,3*, Zhexiang Kuang^1,2,3*, Liwei Fang^1,2,3*, Meili Ge^1,2,3*, Weiping Yuan^1,2 and Jun Shi, MD^1,2,3*

¹State Key Laboratory of Experimental Hematology,National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
²Tianjin Institutes of Health Science, Tianjin, China
³Red Blood Cell Diseases Center & Regenerative Medicine Clinic, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
⁴Red Blood Cell Diseases Center & Regenerative Medicine Clinic, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, AL, China
⁵State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China, Tianjin, China

Elias H Atta, MD, PhD^1,2, Décio Lerner, MsC^3*, Ana Paula Villela, MsC^4* and Leonardo Javier Arcuri, MD, PhD^3,5*

¹CEMO, Instituto Nacional de Câncer, Rio De Janeiro, Brazil
²Oncoclínicas Brasil, Rio de Janeiro, Brazil
³CEMO, Instituto Nacional de Câncer, Rio de Janeiro, Brazil
⁴Laboratório de Imunogenética, Instituto Nacional de Câncer, Rio de de Janeiro, Brazil
⁵Hospital Israelita Albert Eistein, São Paulo, Brazil

Fengkui Zhang^1*, Li Zhang^1*, Chen Yang^2*, Changhe Yue^3*, Jay Ma^4*, Chaomei He^4*, Ping Tsui^4*, Qing Yu Christina Weng^4*, Helen Fu^4*, Hui Yan^3*, Wenru Song⁴ and Bing Han^2*

¹Institute of Hematology & Blood Diseases Hospital, Tianjin, China
²Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing, China
³Kira Pharmaceuticals (Suzhou) Limited, Suzhou, China
⁴Kira Pharmaceuticals (US), Cambridge, MA

Michelle Zhu^1*, Prajwal Sharma^1*, Mutlu Mete^2*, Alper Olcal^1*, Ibrahim F. Ibrahim, MD³, Weina Chan^4* and Taha Bat³

¹University of Texas Southwestern Medical Center, Dallas, TX
²Department of Information Science, University of North Texas, Denton, TX
³Department of Hematology and Oncology, University of Texas Southwestern Medical Center, Dallas, TX
⁴Department of Pathology, University of Texas Southwestern Medical Center, Dallas

Fengkui Zhang^1*, Li Zhang^1,2*, Miao Chen^3*, Hongyan Tong⁴, Xiaoni Li^5*, Wei Wang^5*, Li Liu^5* and Geoffrey Ross^6*

¹Institute of Hematology & Blood Diseases Hospital, Tianjin, China
²Tianjin Institutes of Health Science, Tianjin, China
³Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing, China
⁴The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
⁵Wuhan Createrna Science and Technology Co., Ltd, Wuhan, China
⁶Wuhan Createrna Science and Technology, Ltd, Cornwall, United Kingdom

Yuemin Gong, M.D., PhD^1*, Yawen Zhang^2*, Jianyong Li, MD³, Guangsheng He^4* and Lei Fan^5*

¹Department of Hematology, Department of Hematology, The First Affiliated Hospital of Nanjing Medical University ,Jiangsu Province Hospital,Nanjing,China, Nanjing, China
²Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China
³First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China
⁴The First Affiliated Hospital with Nanjing Medical University, NANJING, China
⁵Lymphoma Center, Department of Hematology, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China