Jonah Pierce^1,2,3*, Brianna Gipson^2*, Lucia Serrano-Marin, MSc^4*, Kimon V Argyropoulos, MD PhD^5*, Susan DeWolf, MD⁶, Scott E. James, MD, PhD¹, Manpreet Kaur, BS^1*, Anastasia Kousa, PhD^1*, Chi L Nguyen, PhD^1,7*, Adhithi Rajagopalan, PhD^1*, Kristen Victor, BA^2*, Kenyon Weis^8*, Andri Leo L Lemarquis, MD, PhD^1* and Marcel R.M. van den Brink, MD, PhD⁹

¹City of Hope National Medical Center, Duarte, CA
²Memorial Sloan Kettering Cancer Center, New York, NY
³Immunology and Microbial Pathogenesis, Weill Cornell Graduate School of Medicine, New York, NY
⁴Department of Immunology, Memorial Sloan Kettering Cancer Center, New York, NY
⁵Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
⁶Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
⁷Gerstner Sloan Kettering Graduate School of Biomedical Sciences, New York, NY
⁸Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY
⁹Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA

Rogers Nahui Palomino, PhD^1*, Etsuko Yasuda, PhD^2*, Nienke Haverkate, MSC^2*, Hergen Spits, PhD^2*, Tim Beaumont, PhD^3*, Bianca Blom, PhD^2* and Mette D. Hazenberg, MD, PhD^2,4,5*

¹Department of Experimental Immunology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, AL, Netherlands
²Department of Experimental Immunology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands
³Department of Medical Microbiology and Infection Prevention, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands
⁴Department of Hematopoiesis, Sanquin Research, Amsterdam, Netherlands
⁵Department of Hematology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands

Hao Yan, PhD¹, Xiangyue Zhang, PhD^2*, Jeanette Baker, PhD^1*, Edgar G. Engleman, MD^2,3* and Robert S. Negrin, MD⁴

¹Department of Medicine, Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University School of Medicine, Stanford, CA
²Department of Pathology, School of Medicine, Stanford University, Palo Alto, CA
³Stanford Cancer Institute, Stanford University, Palo Alto, CA
⁴Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University, Stanford, CA

Huidong Guo^1*, Xinya Jiang^2,3*, Zhigui Wu^2*, Fangqing Zhang^2*, Qianqian Huang, PhD^2*, Bixia Wang^2* and Xiao Jun Huang, MD^4,5,6

¹*Correspondence should be addressed to Xiao-Jun Huang or Huidong Guo, Peking University People's Hospital & Peking University Institute of Hematology, Beijing, China
²Peking University People's Hospital & Peking University Institute of Hematology, Beijing, China
³Research Unit of Key Technique for Diagnosis and Treatments of Hematologic Malignancies, Chinese Academy of Medical Sciencesv, Beijing, China
⁴Peking University People's Hospital, Peking University Institute of Hematology, Beijing, China
⁵Research Unit of Key Technique for Diagnosis and Treatments of Hematologic Malignancies, Chinese Academy of Medical Sciences, Beijing, China
⁶Peking University People’s Hospital, Peking University Institute of Hematology, Beijing, China

Stefan Radtke, PhD¹, Kyle Swing^2*, George S. Laszlo, PhD^2,3*, Andrea Repele, PhD^2*, Greta N. Kanestrom^3*, Nicholas E Petty^2*, Donald K. Hamlin^4*, D. Scott Wilbur, PhD^4*, Brenda M. Sandmaier, MD⁵, Hans-Peter Kiem, MD, PhD¹ and Roland B. Walter, MD, PhD, MS¹

¹Fred Hutchinson Cancer Center, Seattle, WA
²1100 Fairview Avenue North, Fred Hutchinson Cancer Center, Seattle, WA
³1100 Fairview Avenue North, Fred Hutchinson Cancer Center, Seattle
⁴Department of Radiation Oncology, University of Washington, Seattle, WA
⁵Division of Hematology and Oncology, University of Washington School of Medicine, Seattle, WA

Charmaine Fay Soco, PhD¹, Mark R. Krampf^1,2*, Yan Yi Chan^3*, Hana Hoang, MS^1,2*, Nivedita Kunte, BHMS^4*, Gopin Saini, MBBS^5,6*, Kenneth I. Weinberg, MD^1*, Robertson Parkman, MD^7,8, Alice Bertaina, MD, PhD^5,6,9, Rajni Agarwal, MD^1,5,10,11*, Matthew Porteus, MD, PhD^5,6,9,12 and Agnieszka D. Czechowicz, MD, PhD^1,2,5,10

¹Department of Pediatrics, Division of Hematology, Oncology, Stem Cell Transplantation and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA
²Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA
³Department of Pediatrics; Division of Hematology, Oncology, Stem Cell Transplantation and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA
⁴Department of Pediatrics; Division of Hematology, Oncology, Stem Cell Transplantation and Regenerative Medicine, Stanford University, Palo Alto, CA
⁵Center for Definitive and Curative Medicine, Stanford University School of Medicine, Stanford, CA
⁶Department of Pediatrics/ Division of Hematology, Oncology, Stem Cell Transplantation, and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA
⁷Stanford University School of Medicine, Stanford
⁸Department of Pediatrics; Division of Hematology, Oncology, Stem Cell Transplantation and Regenerative Medicine, Stanford University School of Medicine, Pebble Beach, CA
⁹Lucile Packard Children’s Hospital, Palo Alto, CA
¹⁰Lucile Packard Children’s Hospital, Palo Alto
¹¹Center for Definitive and Curative Medicine, Stanford University, Stanford, CA
¹²Stanford Medical School, Stanford, CA

Felicia Kemp, MA^1*, Gail Waltz, MD^1*, Rebecca Brown^2* and Craig Byersdorfer, MD¹

¹University of Pittsburgh, Pittsburgh, PA
²University of Pittsburgh, West Reading, PA

Dejene Tufa, DVM^1*, Eric Hoffmeyer^2*, Kristin Schaller^1*, Ben Kooiman^2*, Elena Woods^3*, Dong Wang^1*, Dallas Jones^4*, Spencer Hall^5* and Michael R Verneris, MD⁶

¹UC Denver, Aurora, CO
²University of Colorado Anschutz Medical Campus, Aurora, CO
³CU Anschutz/Pediatrics, GREENWOOD VILLAGE, CO
⁴University of Colorado, Denver, Aurora, CO
⁵CU Anschutz, Aurora, CO
⁶Department of Pediatrics, Division of Hematology, Oncology, and Bone Marrow Transplantation, University of Colorado School of Medicine and Children's Hospital of Colorado, Aurora, CO

Michael AG Kern^1*, Rèmi Doucet Ladevèze^2*, Haroon Shaikh, PhD^1*, Mariachiara Aloisi^3*, Muthita Khamwong^3*, Juan Vargas^4*, Shreeya Tavkari^3*, Hermann Einsele, MD⁵, Mercedes Gomez de Agüero, PhD^3* and Andreas Beilhack^6*

¹Department of Medicine II, University Hospital Würzburg, Würzburg, Germany
²Institute for Systemsimmunology, University of Würzburg, Würzburg, Germany
³University Würzburg, Würzburg, Germany
⁴University Hospital Würzburg, Würzburg, Germany
⁵Department of Internal Medicine II, University Hospital Wuerzburg, Wuerzburg, Germany
⁶Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany

Stephen P. Persaud, MD, PhD¹, Aditya R. Yelamali, B.A.^2*, Julie K. Ritchey^2* and John F. DiPersio, MD, PhD³

¹Department of Pathology & Immunology, Division of Laboratory and Genomic Medicine, Washington University School of Medicine, Saint Louis, MO
²Department of Medicine, Division of Oncology, Washington University School of Medicine, Saint Louis, MO
³Washington University School of Medicine, St Louis, MO

Lee-Kai Sun, BS^1,2, Archana Ramgopal, DO³, Erica Braverman, MD⁴, Darlene Monlish, Ph.D.^4*, Christopher Wittmann^4*, Manda Ramsey^4*, Richard Caitley^5*, William Hawse, Ph.D.^5* and Craig Byersdorfer, MD⁶

¹University of Pittsburgh School of Medicine, Pittsburgh
²UPMC, Department of Pediatrics, Division of Blood and Marrow Transplantation and Cellular Therapies, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA
³Department of Pediatrics, Division of Blood and Marrow Transplantation and Cellular Therapies, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA
⁴UPMC, Department of Pediatrics, Division of Blood and Marrow Transplantation and Cellular Therapies, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA
⁵University of Pittsburgh, Department of Immunology, Pittsburgh, PA
⁶University of Pittsburgh, Pittsburgh, PA

Stephanie N Hurwitz, MD, PhD^1,2, Danielle R Kobulsky, PSM^3*, Seul K Jung, BS^4*, Jason M Butler, PhD⁵ and Peter Kurre, MD^6,7

¹Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA
²Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA
³Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA
⁴Cell & Molecular Biology Graduate Group, University of Pennsylvania, Philadelphia, PA
⁵Division of Hematology/Oncology, University of Florida, Gainesville, FL
⁶Children's Hospital of Philadelphia, Philadelphia, PA
⁷Department of Pediatrics, University of Pennsylvania, Philadelphia, PA

Sabrina A. Becker, MSc^1*, Julius C. Enssle, MD^2,3,4*, Anne C. Wilke, MD^2,3,5*, Sylvia Pfundt^2*, Nico Zeltner^2*, Ana Jankovic^2*, Sebastian Wolf, MD^2,3,5,6*, Thomas A. Wichelhaus, MD^2,7*, Volkard A. J. Kempf, MD^2,7*, Maria J. G. T. Vehreschild, MD^2,8*, Hubert Serve, MD^2,4,9,10, Thomas Oellerich, MD^2,4,6,11*, Björn Steffen, MD^2,3,4* and Sebastian Scheich, MD^2,3,4,10*

¹Goethe University Frankfurt, University Hospital, Frankfurt Am Main, AA, Germany
²Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany
³German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt am Main, Germany
⁴University Cancer Center (UCT) Frankfurt, Frankfurt am Main, Germany
⁵University Cancer Center (UCT) Frankfurt, University Hospital, Frankfurt am Main, Germany
⁶Frankfurt Cancer Institute, Goethe University, Frankfurt, Germany
⁷Institute of Medical Microbiology and Infection Control, University Hospital Frankfurt, Frankfurt am Main, Germany
⁸Department of Internal Medicine II, Infectious Diseases, University Hospital Frankfurt, Frankfurt am Main, Germany
⁹German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Frankfurt, Germany
¹⁰Frankfurt Cancer Institute, Goethe University, Frankfurt am Main, Germany
¹¹German Cancer Consortium (DKTK), Partner site Frankfurt/Mainz, German Cancer Research Center (DKFZ), Heidelberg, Germany

Haroon Shaikh, PhD^1*, Cindy Flamann, PhD^2,3*, Carina Matos, PhD^4*, Hla Ali, MSc^5*, Michael AG Kern^1*, Marina Kreutz, PhD^4*, Maike Buettner-Herold^6*, Christopher Lischer, MSc^2*, Simon Voelkl, PhD^7,8,9,10*, Christian Kellner, PhD^11*, Katrin Bitterer, MTA^2*, Domenica Saul, MTA^2*, Ernst Holler, MD, PhD^12*, Alma Zernecke, MD^5*, Dimitrios Mougiakakos, MD¹³, Andreas Beilhack^14* and Heiko Bruns, PhD^8,9,15*

¹Department of Medicine II, University Hospital Würzburg, Würzburg, Germany
²Department of Internal Medicine 5 – Hematology/Oncology, University Hospital Erlangen, Erlangen, Germany
³University Hospital Erlangen, Erlangen, DEU
⁴Department of Internal Medicine III, University Hospital Regensburg, Regensburg, Germany
⁵Institute of Experimental Biomedicine, University Hospital Würzburg, Würzburg, Germany
⁶Department of Nephropathology, University Hospital Erlangen, Erlangen, Germany
⁷Department of Internal Medicine 5 - Hematology and Oncology, University Hospital of Erlangen, Erlangen, Germany
⁸Bavarian Cancer Research Center (BZKF), Erlangen, Germany
⁹Deutsches Zentrum Immuntherapie (DZI), Friedrich-Alexander-Universität Erlangen-Nürnberg and University Hospital Erlangen, Erlangen, Germany
¹⁰Department of Internal Medicine 5, Hematology and Oncology, University Hospital Erlangen, Erlangen, Germany
¹¹Division of Transfusion Medicine, Cell Therapeutics and Haemostaseology, LMU University Hospital, LMU Munich, Munich, Germany
¹²Internal Medicine III - Hematology and Oncology, University Hospital Regensburg, Regensburg, Germany
¹³Department of Hematology, Oncology and Cell Therapy, Medical Faculty, Otto-von-Guericke University, Magdeburg, Germany
¹⁴Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany
¹⁵Department of Internal Medicine 5, Hematology and Oncology, University of Erlangen, Erlangen, Bavaria, Germany