-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

508.P1.50 508. Bone Marrow Failure: Acquired: Poster I

Symposia: Bone Marrow Failure: Acquired Program: Oral and Poster Abstracts
Type: Poster
Saturday, December 7, 2024: 5:30 PM-7:30 PM
Halls G-H (San Diego Convention Center)

Yoshitaka Zaimoku, MD, PhD1,2, Kazuyoshi Hosomichi, PhD3*, Noriaki Tsuji, MD, PhD1*, Mikoto Tanabe, MD, PhD1*, Noriharu Nakagawa, MD, PhD1*, Takeshi Yoroidaka, MD, PhD1*, Hiroki Mizumaki, MD1*, Tatsuya Imi, MD, PhD1*, Hiroyuki Maruyama, MD, PhD1*, Kohei Hosokawa, MD, PhD 1, Hiroyuki Takamatsu, MD, PhD1, Hirohito Yamazaki, MD, PhD1*, Kazuya Sakai, MD, PhD4*, Ishikazu Mizuno, MD, PhD5*, Toshihiro Miyamoto, MD, PhD1 and Shinji Nakao, MD, PhD1,6

1Department of Hematology, Kanazawa University, Kanazawa, Japan
2Department of Infection Control and Prevention, Kanazawa University Hospital, Kanazawa, Japan
3Laboratory of Computational Genomics, School of Life Science, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan
4Department of Blood Transfusion Medicine, Nara Medical University, Kashihara, Japan
5Hyogo Cancer Center, Akashi, Japan
6Japanese Red Cross Ishikawa Blood Center, Kanazawa, ISH, Japan

Joshua Glass, MD1,2, Xingmin Feng, PhD2*, Jichun Chen, PhD2 and Neal S. Young, MD2

1Children's National Hospital, Washington, DC
2Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD

Jibran Durrani, MD1, Xingmin Feng, PhD2*, Joshua Glass, MD3, Zhijie Wu, MD, PhD2*, Shouguo Gao, PhD2*, Bhavisha A. Patel, MD2, Jichun Chen, PhD2, Neal S. Young, MD2 and Emma M. Groarke, MD2

1Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, BETHESDA, MD
2Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
3Children's National Hospital, Washington, DC

Kohei Hosokawa, MD, PhD 1, Jong Wook Lee, MD2, Jun Ho Jang, MD3*, Naoshi Obara, MD, PhD4*, Masashi Sawa5*, Kensuke Usuki, MD, PhD6, Gaku Oshikawa, MD7*, Masahiro Kizaki, MD8, Koji Nagafuji, MD, PhD9, Ting-An Lin, MD10*, Hitoshi Hanamoto, MD11*, Yeung-Chul Mun, MD, PhD12*, Toshiro Kawakita, MD, PhD13*, Kazunori Imada, MD, PhD14*, June-Won Cheong, MD, PhD15, Sung-Soo Park, MD, PhD16*, Takayuki Tabayashi, MD, PhD8*, Masaru Gamou17*, Mami Shimizu18*, Kenta Murotani, MD19* and Hirohito Yamazaki, MD, PhD20*

1Department of Hematology, Kanazawa University Hospital, Kanazawa, Japan
2Division of Hematology-Oncology, Hanyang University Seoul Hospital, Seoul, Korea, Republic of (South)
3Department of Hematology, Sungkyunkwan University Samsung Medical Center, Seoul, Korea, Republic of (South)
4Department of Hematology, University of Tsukuba Hospital, Tsukuba, Japan
5Department of Hematology and Oncology, Anjo Kosei Hospital, Anjyo, Japan
6NTT Medical Center Tokyo, Tokyo, Japan
7Department of Hematology, Japanese Red Cross Musashino Hospital, Musashino, Japan
8Department of Hematology, Saitama Medical Center, Saitama Medical University, Kawagoe, Japan
9Department of Hematology, Kurume University Hospital, Kurume, Japan
10Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
11Department of Hematology, Kindai University Nara Hospital, Ikoma, Japan
12Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea, Republic of (South)
13Department of Hematology, National Hospital Organization Kumamoto Medical Center, Kumamoto, Japan
14Department of Hematology, Japanese Red Cross Osaka Hospital, Osaka, Japan
15Division of Hematology, Department of Internal Medicine, Yonsei University College of Medicine, Severance Hospital, 50 Yonsei-ro, Seodaemun-gu, Seoul, Korea, Republic of (South)
16Division of Hematology, Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul, Korea, Republic of (South)
17Kyowa Kirin Co., Ltd., Chiyoda-Ku, Tokyo, Japan
18Kyowa Kirin Co., Ltd., Tokyo, Japan
19Biostatistics Center, Kurume University, Kurume, Japan
20Division of Medical Safety, Kanazawa University Hospital, Kanazawa, Japan

Rio Takahashi1*, Yoshitaka Zaimoku, MD, PhD2, Kohei Hosokawa, MD, PhD 2, Seishi Ogawa, MD, PhD3,4,5, Yoshiyuki Takahashi6, Takako Miyamura7, Yasushi Onishi, MD, PhD8*, Takashi Koike9*, Tetsuya Nishida10*, Naoyuki Uchida11, Noriko Doki12, Masatsugu Tanaka13*, Tetsuya Eto14*, Mitsuhiro Itagaki15*, Masashi Sawa16*, Yuta Hasegawa17*, Takahiro Fukuda18*, Makoto Onizuka19, Yoshiko Atsuta20,21*, Shinji Nakao, MD, PhD2 and Takamasa Katagiri22*

1Department of Clinical Laboratory Science, Kanazawa University, Kanazawa, ISH, Japan
2Department of Hematology, Kanazawa University, Kanazawa, Japan
3Kyoto University, Sakyoku, KYO, Japan
4Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan
5Department of Medicine, Karolinska Institute, Stockholm, Sweden
6Department of Pediatrics, Nagoya University, Nagoya, Japan
7Department of Pediatrics, Osaka University Hospital, Osaka, Japan
8Department of Hematology, Tohoku University Hospital, Sendai, Japan
9Department of Pediatrics, Tokai University, Isehara, Japan
10Department of Hematology, Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital, Nagoya, Japan
11Department of Hematology, Federation of National Public Service Personnel Mutual Aid Associations TORANOMON HOSPITAL, Tokyo, Japan
12Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan
13Department of Hematology, Kanagawa Cancer Center, Yokohama, Japan
14Department of Hematology, Hamanomachi Hospital, Fukuoka, Japan
15Department of Hematology, Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital, Hiroshima, Japan
16Department of Hematology and Oncology, Anjo Kosei Hospital, Anjyo, Japan
17Department of Hematology, Hokkaido University Hospital, Sapporo, Japan
18Department of Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital, Tokyo, Japan
19Department of Hematology/Oncology, Tokai University, Isehara, Japan
20Department of Registry Science for Transplant and Cellular Therapy, Aichi Medical University, Nagakute, Japan
21The Japanese Data Center for Hematopoietic Cell Transplantation, Nagakute, Japan
22Department of Clinical Laboratory Science, Kanazawa University, Kanazawa, Japan

Naoko Hosono, MD, PhD1, Ken Ishiyama, MD, PhD2, Hiroki Yamaguchi, MD3, Masahide Yamazaki, MD, PhD4*, Hiroyuki Maruyama, MD, PhD5*, Kensuke Usuki, MD, PhD6, Kazuki Tanimoto, MD, PhD7*, Hiroyuki Sugiura, MD8*, Noboru Asada, MD, PhD9, Seishi Ogawa, MD, PhD10, Yuzuru Kanakura, MD, PhD11, Itaru Matsumura, MD12, Koichi Akashi, MD, PhD13* and Shinji Nakao, MD, PhD14,15

1Department of Hematology and Oncology, Faculty of Medical Sciences, University of Fukui, Fukui, Japan
2Department of Hematology, National Center for Global Health and Medicine, Tokyo, Japan
3Department of Hematology, Nippon Medical School Hospital, Tokyo, Japan
4Keiju Medical Center, Nanao, Japan
5Kanazawa University Graduate School of Medical Science, Kanazawa-Shi, JPN
6NTT Medical Center Tokyo, Tokyo, Japan
7Division of Hematology and Oncology, Japanese Red Cross Fukuoka Hospital, Fukuoka, FKO, JPN
8Department of Hematology, Chugoku Central Hospital of Japan Mutual Aid Association of Public School Teachers, Fukuyama, Japan
9Department of Hematology and Oncology, Okayama University Hospital, Okayama, Japan
10Kyoto University, Sakyoku, KYO, Japan
11Department of Hematology, Sumitomo Hospital, Osaka, Japan
12Department of Hematology and Rheumatology, Kindai University Faculty of Medicine, Osaka-Sayama, Japan
13Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
14Department of Hematology, Kanazawa University, Kanazawa, Japan
15Japanese Red Cross Ishikawa Blood Center, Kanazawa, Japan

Phillip Scheinberg, MD1, Diego Villa Cle, MD, MBA, PhD2*, Berangere Devalet3*, Valentina Giai, MD, PhD4*, Cristina Barrenetxea Lekue, PhD5*, Hsuan-Yu Lin6*, Zsolt Nagy, MD7*, Jun-ichi Nishimura, MD, PhD8, Jens Panse, MD9,10, Agnieszka Piekarska11*, Jörg Schubert, MD12*, Kazutaka Sunami, MD, PhD13, Mustafa Yenerel14*, Anita Appius, PhD15*, Brittany Gentile, PhD16*, Shino Iwase17*, Himika Patel, PharmD18*, Sasha Sreckovic, MD19* and Austin G. Kulasekararaj, MD, MBBS, FRCPath, MRCP20,21

1Hospital A Beneficência Portuguesa, Sao Paulo, SP, Brazil
2Ribeirão Preto School of Medicine, University of São Paulo, Ribeirão Preto, Brazil
3Department of Hematology, Université Catholique de Louvain (UCLouvain), CHU UCL Namur, Yvoir, Belgium
4Hematology, AOU Città della Salute e della Scienza di Torino, Turin, Italy
5Hospital Universitario de Basurto, Bilbao, Spain
6Division of Hematology/Oncology, Department of Internal Medicine,, Changhua Christian Hospital, Changhua, Taiwan
7Department of Internal Medicine and Hematology, Semmelweis University, Budapest, Hungary
8Osaka University Graduate School of Medicine, Osaka, Japan
9Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, University Hospital RWTH Aachen, Aachen, Germany
10Department of Oncology, Hematology, Hemostaseology and Stem Cell Transplantation, University Hospital RWTH Aachen, Aachen, Germany
11Department of Hematology and Transplantology, Medical University of Gdansk, Gdansk, Poland
12Elblandklinikum Riesa, Riesa, Germany
13Department of Hematology, NHO, Okayama Medical Center, Okayama, Japan
14Istanbul University, Istanbul, Turkey
15F. Hoffmann-La Roche Ltd, Basel, Switzerland
16Genentech, Inc., South San Francisco, CA
17F. Hoffmann-La Roche Ltd, Basel, Switzerland, Basel, Switzerland
18Genentech, Inc., Simi Valley, CA
19Genentech, Inc, South San Francisco
20King’s College Hospital-NHS Foundation Trust, NIHR/Wellcome King’s Clinical Research Facility, and King’s College London, London, United Kingdom
21King's College London, National Institute for Health and Care Research and Wellcome King’s Research Facility, London, United Kingdom

Eléonore Kaphan, MD1*, Anouk Walter Petrich, MD2*, Lise Larcher3*, Thierry Leblanc4*, Mony Fahd, MD MSc5,6*, Benedicte Bruno7*, Edouard Forcade, MD, PhD8*, Cecile Renard, MD9*, Arthur Sterin10*, Michael Loschi, MD, PhD11*, Elodie Lainey, PhD, PharmD12*, Jean Soulier, MD13,14*, Caroline Kannengiesser15*, Gerard Socie, MD, PhD16,17,18, Regis Peffault De Latour1,19,20,21,22*, Jerome Lambert, MD, PhD23* and Flore Sicre de Fontbrune, MD24*

1Hematology / Transplantation, Hospital St Louis, Paris, France
2Biostatistics and Medical Information Department, Saint Louis University Hospital, AP-HP, Université Paris Cité, Paris, France
3Hopital Saint-Louis and University De Paris, Paris, FRA
4Service d’Hematologie et d’Immunologie Pédiatrique, Centre de Reference Aplasies Medullaires Acquises et Constitutionnelles, Hôpital Robert-Debré, Assistance Publique Hôpitaux de Paris and Université Paris Cité, Paris, France
5Saint-Louis Academic Hospital, GHU Ap-HP Nord Université Paris Cité, French National Reference Center for Severe Aplastic Anemia, Paris, France
6Pediatric hematology and immunology department, Robert-Debré Hospital, GHU APHP Nord Université Paris-Cité, Paris, France
7Chru Lille, Jeanne De Flandre Hématologie Pédiatrique, Lille, FRA
8Service d'Hématologie Clinique et Thérapie Cellulaire, CHU Bordeaux, Hopital Haut-Leveque, Pessac, France
9Institute of Hematology and Pediatric Oncology, Lyon, France
10Department of Pediatric Hematology, Immunology and Oncology, APHM, La Timone Children Hospital, Department of Pediatric Hematology, Immunolog, Marseille, France
11Hematology Department, Nice University Hospital, Nice, France
12Robert Debre Hospital, Paris, FRA
13Hopital Saint-Louis Centre Hayem 2ETG, Paris, France
14INSERM U944/CNRS UMR7212, Institut de Recherche Saint-Louis, Paris, France
15Assistance Publique-hôPitaux De Paris, Bichat, Paris, FRA
16INSERM UMR 976, Université Paris Cité, Institut de Recherche Saint-Louis (IRSL), Paris, France
17Hematology / Transplantation, Hematology Transplantation, Paris, France
18French Reference Center for Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria, Saint Louis Hospital and University Paris Diderot, Paris, France
19French Reference Center for Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria, Paris, France
20Hematology Branch, NHLBI, NIH, Bethesda, MD
21Severe Aplastic Anemia Working Party, European Group for Blood and Marrow Transplantation (EBMT), Leiden, Netherlands
22Société Française de Greffe de Moelle et de Thérapie Cellulaire (SFGM-TC), Hôpital Henri Herriot, CHU, Lyon, France
23Hôpital Saint Louis, Biostatistics and Medical Information Department, Saint Louis University Hospital, AP-HP, Université Paris Cité, Paris, FRA
24Centre de Référence Aplasie Médullaire, Service d’Hématologie Greffe, Assistance Publique des Hôpitaux de Paris, Hôpital Saint-Louis, Paris, France

Erika Ren, BSc1*, Katayoun Elizabeth Khalilian, BS1*, Mutlu Mete2*, Carmelo Gurnari, MD, PhD3,4, Jaroslaw Maciejewski5, Carlos Bravo-Perez, MD5,6* and Taha Bat7

1University of Texas Southwestern Medical Center, Dallas, TX
2Department of Information Science, University of North Texas, Denton, TX
3Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
4Cleveland Clinic Foundation, Cleveland, OH
5Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
6Centro Regional de Hemodonación, IMIB-Arrixaca, CIBERER, University of Murcia, Murcia, Spain
7Department of Hematology and Oncology, University of Texas Southwestern Medical Center, Dallas, TX

Lauren T. Reiman, BSc1*, My H. Vu, MS2*, Michael Cotez-Bacolot, BS3*, Brent L. Wood, MD, PhD4,5 and Alexandra E. Kovach, MD4,6*

1Keck School of Medicine, University of Southern California, Los Angeles, CA
2Biostatistics, Children's Hospital Los Angeles, Los Angeles, CA
3Department of Pathology and Laboratory Medicine, Children's Hospital of Los Angeles, Los Angeles
4Keck School of Medicine of University of Southern California, Los Angeles, CA
5Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA
6Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA

Elena E. Solomou, MD1, Alkmini Anastasiadi2*, Maria Papaioannou3*, Maria Angelopoulou4*, Panagiotis Zikos, MD5*, Ioannis Assimakopoulos6*, Maria Dimou, MD7*, Panagiotis Tsaftaridis8*, Jens Panse, MD9,10 and Vasileios Tzounakas, PhD11*

1Department of Internal Medicine, University of Patras Medical School, Rion, Greece
2Department of Biochemistry, University of Patras Medical School, Patras, GRC
31st Department of Internal Medicine, AHEPA University Hospital of Thessaloniki, Thessaloniki, Greece
4Hematology Department – BMT Unit, Laikon General Hospital, Athens, Greece
5Department of Hematology, Aghios Andreas General Hospital, Patras, Greece, Patras, Greece
6Department of Hematology, University of Athens Medical School , Laikon Hospital, ATHENS, GRC
7Department of Hematology and Bone Marrow transplantation Unit, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece
8Laikon Hospital of Athens, Athens, GRC
9Center for Integrated Oncology - Aachen Bonn Cologne Duesseldorf (CIO-ABCD), Aachen, Germany
10Center for Integrated Oncology - Aachen Bonn Cologne Duesseldorf (CIO-ABCD), Aachen, Aachen, Germany
11Department of Biochemistry, University of Patras Medical School, Patras, Greece

Lucy C Fox, BSc, FRACP, FRCPA, MBBS1,2,3, Sally Hunter4*, Stephen Ting, MBBS, FRACP, FRCPA, PhD5,6, Le Thi Phuong Thao, PhD7*, Stephane Heritier, PhD8*, Anthony K. Mills, MBBS, FRACP, FRCPA9, Dominic Pepperell10*, William S Stevenson, MBBS, FRACP, FRCPA, PhD11*, Ilona Cunningham, MBBS FRACP FRCPA12, Jennifer Curnow, MBBS, FRACP, FRCPA, PhD13*, Devendra Hiwase, MD, MBBS, PhD, FRACP, FRCPA14,15, Robin Filshie, PhD, FRACP, FRCPA16, Kylie Mason, MBBS, PhD, FRACP, FRCPA17, Sushrut S. Patil18*, Sonali Ashok Sadawarte, MD, DM, FRACP, MBBS19*, Frank Caleb Firkin20*, Jeffrey Szer, MBBS21,22, Paul Lacaze23*, Kate Wilson24*, Lisa Higgins25*, Lauren Young, PhD8*, Vanessa Fox, BSc8*, Robyn Sutherland, BN, BSc8*, Neil A Waters, BSc26*, Erica M. Wood, MBBS, PhD, FRACP, FRCPA27,28*, Zoe K McQuilten, MBBS, PhD29,30 and Piers Blombery, MBBS31,32

1Department of Clinical Haematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, Australia
2Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia
3Transfusion Research Unit, Monash University, Melbourne, Australia
4Peter MacCallum Cancer Centre, Melbourne, Australia
5Monash University-Alfred Health, Box Hill, Vic, AUS
6Department of Haematology, Eastern Health and Monash University, Elwood, VIC, Australia
7School of Public Health and Preventive Medicine, Monash University, Melbourne, AUS
8School of Public Health and Preventative Medicine, Monash University, Melbourne, Australia
9Division of Cancer Services, Princess Alexandra Hospital, Brisbane, QLD, Australia
10Fiona Stanley Hospital, Murdoch, AUS
11Royal North Shore Hospital, Sydney, AUS
12Haematology Department Concord Hospital, Concord and University of Sydney, Sydney, Australia
13Westmead Hospital, Sydney, AUS
14University of Adelaide, Adelaide, SA, Australia
15Royal Adelaide Hospital, Adelaide, SA, Australia
16St. Vincent's Hospital Melbourne, Fitzroy, VIC, AUS
17Royal Melbourne Hospital, Parkville, VIC, AUS
18Department of Malignant Haematology & Stem Cell Transplantation, The Alfred Hospital, Melbourne, VIC, Australia
19Royal Hobart Hospital, Hobart, TAS, AUS
20St. Vincent's Hospital, Fitzroy, VIC, AUS
21Department of Clinical Haematology, Peter MacCallum Cancer Centre and The Royal Melbourne Hospital, Melbourne, VIC, Australia
22Department of Medicine, The University of Melbourne, Parkville, VIC, Australia
23Monash University, Melbourne, AUS
24University of Sydney, Sydney, Australia
25Monash University, Melbourne, Australia
26Transfusion Research Unit, School of Public Health and Preventive Medicine, Monash University, Melbourne, AUS
27School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia
28Monash Health, Melbourne, Australia
29Department of Haematology, Monash Health, Melbourne, Australia
30Transfusion Research Unit, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia
31Peter Maccallum Cancer Centre, East Melbourne, VIC, Australia
32Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC, Australia

Mengran Gao1,2*, Ling Deng1,2*, Xinrui Zhang1,2*, Chunyan Liu1,2* and Rong Fu, MD1,2

1Department of Hematology, Tianjin Medical University General Hospital, Tianjin, China
2Tianjin Key Laboratory of Bone Marrow Failure and Malignant Hemopoietic Clone Control, Tianjin, China

Yilin Liu1*, Meili Ge2*, Yingchang Mi, MD1 and Jinbo Huang1*

1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China, Tianjin, China
2State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China

Flore Sicre de Fontbrune, MD1*, Edouard Forcade, MD, PhD2*, Louis Terriou, M.D3*, Alice Garnier, MD4*, Vincent Alcazer, MD5*, Nicolas Daguindau6*, Lynda Maafa7*, Isabelle Brindel, PhD8*, Regis Peffault de Latour, MD, PhD9,10,11* and Sylvie Chevret12*

1Centre de Référence Aplasie Médullaire, Service d’Hématologie Greffe, Assistance Publique des Hôpitaux de Paris, Hôpital Saint-Louis, Paris, France
2Service d'Hématologie Clinique et Thérapie Cellulaire, CHU Bordeaux, Hopital Haut-Leveque, Pessac, France
3Hopital Cl HURIEZ, LILLE, FRA
4CHU Nantes Hôpital Hôtel Dieu Hématologie Clinique, Nantes, France
5Hematology department, Centre Hospitalier Lyon Sud, Pierre Bénite, FRA
6Hematologie, Centre Hospitalier Annecy Genevois, Metz-Tessy, FRA
7Saint-Louis Hospital, GHU AP-HP Nord Université Paris Cité, French National Reference Center for Severe Aplastic Anemia, Paris, France
8Saint-Louis Hospital, GHU AP-HP Nord Université Paris Cité, French National Reference Center for Severe Aplastic Anemia, PARIS, France, FRA
9French Référence Center for Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria, Paris, France
10Hôpital Saint-Louis, Université Paris Cité, Paris, France
11Hematology and Transplant Unit, French National Reference Center for Aplastic Anemia, Hopital Saint Louis, APHP, Paris, France
12Biostatistics and Medical Information Department, Saint Louis Hospital, Assistance Publique — Hôpitaux de Paris (AP-HP), Paris, France

Zixi Yin1*, Xiaofan Zhu, MD2,3,4,5, Yang Wan, MD PhD6*, Yangyang Gao1* and Jun Li7*

1State Key Laboratory of Experimental Hematology Chinese Academy of Medical Sciences Institute of Hematology and Blood Diseases Hospital, Tianjin, China
2Tianjin Institutes of Health Science, Tianjin, China
3Hospital, Tianjin, China
4Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, Tianjin, Tianjin, China
5Tianjin Institutes of Health Science, Tianjin 301600, China
6Department of Pediatric Hematology and Oncology, State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology& Blood Diseases Hospital, Chinese Academy of Medical Sciences& Peking Union Medical College, Tianjin, China
7State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences&Peking Union Medical College, Tianjin, China

Austin G. Kulasekararaj, MD, MBBS, FRCPath, MRCP1,2,3, Jaroslaw Czyz4*, Catherine Flynn5*, Gabriela Roncone Gastal6*, Marek Hus7*, Chrysavgi Lalayanni, MD8*, Erfan Nur9,10*, Phillip Scheinberg, MD11, Yasutaka Ueda12*, Alessandro Maria Vannucchi13*, Maria Vidriales Vicente14*, Iige Viigimaa15*, Simon Buatois16*, Alice C. Chang17*, Sammy Chebon16* and Alexander Röth, MD18

1National Institute for Health Research and Wellcome King's Clinical Research Facility, London, United Kingdom
2King's College Hospital, London, United Kingdom
3Department of Hemato-oncology, Kings College London, London, United Kingdom
4Department of Hematology, Nicolaus Copernicus University, Bydgoszcz, Poland
5Department of Haematology, St. James' Hospital, Dublin, Ireland
64. Centro de Hematologia e Oncologia (C.H.O.), Joinville, Brazil
7Department of Hemato Oncology and Bone Marrow Transplantation, Medical University of Lublin, Lubin, Poland
8Hematology Department – BMT Unit, G Papanicolaou Hospital, Thessaloniki, Greece
9Department of Hematology, Amsterdam University Medical Centers, Amsterdam, Netherlands
10Department of Molecular Hematology, Sanquin Research and Landsteiner Laboratory, Amsterdam, Netherlands
11Division of Hematology, Hospital A Beneficencia Portuguesa de São Paulo, São Paulo, Brazil
12Osaka University Graduate School of Medicine, Osaka, Japan
13CRIMM, Center Research and Innovation of Myeloproliferative Neoplasms, University of Florence and AOU Careggi, Florence, Italy
14Hospital Universitario de Salamanca, Salamanca, Spain
15Hematology Department, North Estonia Medical Centre, Tallinn, Estonia
16F. Hoffmann-La Roche Ltd, Basel, Switzerland
17Genentech, Inc., South San Francisco
18Department of Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

*signifies non-member of ASH