Peipei Zhang^1,2*, Anlun Li, PhD^3*, Yanyan Liu, MD, PhD^4*, X. Long Zheng, MD, PhD³ and Xinyang Zhao, PhD⁵

¹Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS
²Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, China
³Pathology and laboratory medicine, University of Kansas Medical Center, Kansas City, KS
⁴Department of Internal Medicine, Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, China
⁵Pathology and laboratory Medicine, University of Kansas Medical Center, Kansas City, KS

Christian Andrea Di Buduo, PhD^1*, Carolina Paula Miguel^2*, Giulia Della Rosa^2*, Vittorio Abbonante, PhD^1,3*, Alessandro Malara^4*, Daniele Cattaneo^5*, Delfina Tosi^6*, Umberto Gianelli, Prof^7*, Alessandra Iurlo, MD, PhD^8* and Alessandra Balduini, MD^9,10

¹University of Pavia, Pavia, ITA
²University of Pavia, Pavia, Lombardia, Italy
³Department of Health Sciences, Magna Graecia University, Catanzaro, Italy
⁴Department of Molecular Medicine, University of Pavia, Pavia, Italy
⁵Hematology, Foundation IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano, Italy
⁶University of Milan, Milano, Italy
⁷Department of Health Sciences, Università degli Studi di Milano, Milan, Italy
⁸Hematology Division, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy
⁹Tufts University, Medford, MA
¹⁰University of Pavia, Medford, MA

Huang Wu, Ph.D^1*, Yao Lu^1*, Denglian Sun^1*, Huayu Lin, Ph.D^2*, Wenjun Xia^1*, Ruichi Chen^1*, Jun Chen^1*, Jiaying Xie^1*, Rong Feng^1*, Lijie Ren^1*, Zeqing Miao^1*, Junling Liu, Ph.D^3*, Yang Yu, M.D. & Ph.D^2* and Aiqing Wen, M.D. & Ph.D^1*

¹Department of Blood Transfusion, Daping Hosptial of Army Medical University, Chongqing, China
²Department of Transfusion Medicine, First Medical Center of Chinese PLA General Hospital, Beijing, China
³Department of Biochemistry and Molecular Cell Biology, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Jiaqian Qi, MD, PhD^1,2,3*, Jie Yin^1,2,3*, Meng Zhou, MD, PhD^3,4,5*, Haohao Han, MD, PhD^1*, Depei Wu, MD, PhD^1,3,6 and Yue Han, MD, PhD^3,5*

¹National clinical research center for hematologic diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China
²Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China
³Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, Suzhou, China
⁴Hematology, The First Affiliated Hospital of Soochow University, National clinical research center for hematologic diseases, Institute of Blood and Marrow Transplantation, Suzhou, China
⁵Institute of Blood and Marrow Transplantation, Suzhou, China
⁶Department of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China

Maximilian Englert^1*, Gabriel H.M. Araujo^1*, Harald Schulze, PhD¹, Bernhard Nieswandt, PhD^1,2* and Zoltan Nagy, PhD^1*

¹Institute of Experimental Biomedicine, University Hospital Würzburg, Würzburg, Germany
²Rudolf Virchow Center for Integrative and Translational Bioimaging, University of Würzburg, Würzburg, Germany

Molly Brakhane, MSc¹, Vittorio Abbonante, PhD^2*, Angelo Laranjeira^3*, Christian Andrea Di Buduo, PhD^2*, Brooke Sadler, PhD⁴, Katrina Ashworth^5*, Tim Kong, MSc³, Fan He, PhD¹, Mary Fulbright, MSc^3*, Dong Chen, MD, PhD⁶, Regina Clemens, MD^7*, Elena Pegoraro^8*, Michele P. Lambert, MD⁹, Kandace Gollomp, MD¹⁰, Jorge Di Paola, MD⁵, Alessandra Balduini, MD¹¹ and Stephen Oh, MD, PhD¹²

¹Division of Hematology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO
²University of Pavia, Pavia, ITA
³Division of Hematology, Department of Medicine, Washington University School of Medicine, St Louis, MO
⁴Pediatrics, Washington University School of Medicine, Saint Louis, MO
⁵Department of Pediatrics, Washington University School of Medicine, St Louis, MO
⁶Division of Hematopathology, Mayo Clinic, Rochester, MN
⁷Departmnet of Pediatrics, Washington University at St Louis, St Louis, MO
⁸University of Padova, Padova, ITA
⁹Children's Hospital of Philadelphia, Philadelphia, PA
¹⁰Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA
¹¹University of Pavia, Medford, MA
¹²Washington University School of Medicine, Saint Louis, MO

Kaoru Takasaki, MD¹, Kristin Murphy, PhD^2*, Eric K. Wafula, PhD^3*, Christopher S. Thom, MD, PhD⁴, Sara S. Kumar^1*, Ying Ting Sit, PhD^1*, Alyssa Gagne^5*, Deborah L. French, PhD^5*, Laurie A. Steiner, MD⁶ and Stella T. Chou, MD^1,5

¹Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA
²University of Rochester, Rochester, NY
³Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA
⁴Division of Neonatology, Children's Hospital of Philadelphia, Philadelphia, PA
⁵Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA
⁶Department of Pediatrics, University of Rochester, Rochester, NY

Maria Barrachina, PhD¹, Karen Guo^2*, Daniela Freire^2*, Virginia Camacho, PhD^1,2, Isabelle C Becker, PhD, MSc^1,2, Emma Nikols^2*, Julia Tilburg, PhD^1,2, Joseph E. Italiano, PhD^1,2 and Kellie R Machlus, PhD^1,2

¹Harvard Medical School, Boston, MA
²Vascular Biology Program, Boston Children's Hospital, Boston, MA

Kamaleldin E Elagib^1*, Sijie Liu^2*, Valentin Burguener^1*, Ranjit Sahu^1*, Deepika Kotay^1*, Gerhard Wolber^2*, Ciorsdaidh Watts^3* and Adam Goldfarb^1*

¹Department of Pathology, University of Virginia Health Sciences Center, Charlottesville, VA
²Institut für Pharmazie, Freie Universität Berlin, Berlin, Germany
³School of Chemistry, University of Glasgow, Glasgow, United Kingdom

Roelof H Bekendam, MD, PhD^1,2, Andrew Stone, PhD^1,3, Virginia Camacho, PhD¹, Isabelle C Becker, PhD, MSc¹, Clementine Payne^1*, Estelle Carminita, PhD^1*, Maria Barrachina, PhD⁴, Jakub Kaplan^5*, Luis Batista, PhD⁶, Sharmista Pal, PhD^5*, Joseph E. Italiano, PhD¹ and Kellie R Machlus, PhD¹

¹Vascular Biology Program, Boston Children's Hospital, Boston, MA
²Division of Hematology and Hematologic Malignancies, Beth Israel Deaconess Medical Center, Roslindale, MA
³Biology Department, Brandeis University, Waltham, MA
⁴Harvard Medical School, Boston, MA
⁵Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA
⁶Hematology, Washington University School of Medicine in St. Louis, St. Louis, MO

Christopher J Czura, PhD^1*, Caroline Benner^2*, Brooke Le^2*, Kimiko Harada^1*, Melanie McWade, PhD^1*, Navid Khodaparast, PhD^1* and Alejandro Covalin, PhD^3*

¹Spark Biomedical Inc, Dallas, TX
²Spark Biomedical, Dallas, TX
³Spark Biomedical, Inc., Dallas, TX