Yanmin Zhao, MD^1,2,3*, Yi Luo^2,3,4, Jimin Shi^1,2,3*, Shunqing Wang^5*, Caixia Wang^5*, Erlie Jiang⁶, Chen Liang^7*, Xiaoyu Zhu⁸, Xuejun Zhang^9*, Fankai Meng^10*, Hua Jin^11*, Yeqian Zhao^2,3,12*, Jian Yu, MD^1,2,3*, Xiaoyu Lai, MD^2,3,12*, Lizhen Liu^2,3,12*, Huarui Fu, MD^1,2,3*, Yishan Ye, MD^1,2,3*, Congxiao Zhang, MD^2,3,13*, Tao Wang^14*, Lifan Tu^15*, Xunqiang Wang^16* and He Huang, MD^2,3,17*

¹Bone Marrow Transplantation Center of The First Affiliated Hospital Liangzhu Laboratory, Zhejiang University School of Medicine, Hangzhou, China
²Institute of Hematology, Zhejiang University, Hangzhou, China
³Zhejiang Province Engineering Research Center for Stem Cell and Immunity Therapy, Hangzhou, China
⁴Bone Marrow Transplantation Center of The First Affiliated Hospital & Liangzhu Laboratory, Bone Marrow Transplantation, the First Affiliated Hospital of Zhejiang Universit, Hangzhou, China
⁵Department of Hematology, Guangzhou First People's Hospital, Guangzhou, China
⁶Department of Hematology, Hematology Hospital, Chinese Academy of Medical Sciences, Tianjin, China
⁷Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
⁸Department of Hematology, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China
⁹Department of Hematology, The Second Hospital of Hebei Medical University, Shijiazhuang, China
¹⁰Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
¹¹Department of Hematology, Nanfang Hospital of Southern Medical University, Guangzhou, China
¹²Bone Marrow Transplantation Center of The First Affiliated Hospital & Liangzhu Laboratory, Zhejiang University School of Medicine, Hangzhou, China
¹³Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
¹⁴Department of Clinical Biostatistics, Chia Tai Tianqing Pharmaceutical Group Co., Ltd, Nanjing, China
¹⁵Chia Tai Tianqing Pharmaceutical Group Co., Ltd, Nanjing, AL, China
¹⁶Chia Tai Tianqing Pharmaceutical Group Co., Ltd, Nanjing, China
¹⁷Bone Marrow Transplantation Center of The First Affiliated Hospital & Liangzhu Laboratory, Zhejiang University School of Medicine, hangzhou, China

Hannah Choe, MD¹, Amandeep Salhotra, MD², Nosha Farhadfar, MD^3*, Mi Kwon^4*, Britnie Thomas, PhD^5*, Vedran Radojcic^6*, Chuan Tian^5*, Shuyuan Lou^5*, Daniel Wolff, MD^7* and Stephanie J. Lee^8*

¹Department of Internal Medicine, Division of Hematology, The Ohio State University Comprehensive Cancer Center - James Cancer Hospital, Columbus, OH
²Hematology and HCT, City of Hope National Medical Center, Duarte, CA
³Sarah Cannon Transplant and Cellular Therapy Program, Methodist Hospital, San Antonio, TX
⁴Hospital General Universidad Gregorio Marañon, Madrid, Spain
⁵Incyte Corporation, Wilmington, DE
⁶Syndax Pharmaceuticals, Inc., Waltham, MA
⁷Department of Internal Medicine III, Hematology and Oncology, University Hospital Regensburg, Bonn, Germany
⁸Fred Hutchinson Cancer Center, Seattle, WA

Xiaodong Mo^1*, He Huang, MD^2*, Feng Chen^3*, Yi Luo², Jia Chen^3*, Erlie Jiang⁴, Yicheng Zhang^5*, Linghui Xia^6*, Chengwei Luo Luo, M.D.^7*, Xinchuan Chen, MD, PhD^8*, Nainong Li, MD, PhD⁹, Ming Jiang^10*, Sujun Gao^11*, Dongqin Yang^12*, Qingli Zuo^12*, Yimin Chen^12*, Li Yao^12*, Pan Liang^12* and Depei Wu, MD, PhD³

¹Peking University Institute of Hematology, Peking University Peoples’ Hospital, Beijing, China
²Bone marrow transplantation department, The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China
³Department of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China
⁴Department of Hematology, Hematology Hospital, Chinese Academy of Medical Sciences, Tianjin, China
⁵Department of hematopathology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⁶Department of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⁷Department of Hematology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China
⁸Department of Hematology, West China Hospital, Sichuan University, Chengdu, China
⁹Department of Hematology, Fujian Medical University Union Hospital, Fuzhou, China
¹⁰Department of Hematology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China
¹¹Department of Hematology, The First Hospital of Jilin University, Changchun, China
¹²Abbisko Therapeutics Co, Ltd, Shanghai, China

Robert Zeiser, MD^1,2,3,4, Hannah Choe, MD⁵, Holger Adelmann, MD, PhD^6*, Nader N. Youssef, MD, MBA^7*, Anastasia Eremeeva^6*, François Collin^6* and Yi-Bin Chen, MD, MS⁸

¹German Cancer Consortium (DKTK), Partner Site Freiburg and German Cancer Research Center (DKFZ), Heidelberg, Germany
²Comprehensive Cancer Center Freiburg (CCCF), Medical Center – University of Freiburg, Freiburg, Germany
³Department of Internal Medicine I, Hematology, Oncology and Stem Cell Transplantation, Medical Center - University of Freiburg, Faculty of Medicine, Freiburg, Germany
⁴Center for Integrative Biological Signaling Studies (BIOSS and CIBSS), University of Freiburg, Freiburg im Breisgau, Germany
⁵Blood and Marrow Transplantation Program, James Cancer Hospital, The Ohio State University, Columbus, OH
⁶Ironwood Pharmaceuticals, Inc., Basel, Switzerland
⁷Ironwood Pharmaceuticals, Inc., Boston
⁸Hematopoietic Cell Transplant and Cell Therapy Program, Massachusetts General Hospital, Boston, MA

Zengkai Pan, MD, PhD^1*, Yujun Deng, M.S.^2*, Jingtao Huang^3*, Aijie Huang, MD^4*, Xiong Ni, MD, PhD^5*, Lei Gao, MD, PhD^6*, Chuanhe Jiang, MD, PhD^7*, Luxiang Wang, MD, PhD^7*, Zilu Zhang, MD, PhD^7*, Quan Gu, PhD^8*, Hui Cheng^9*, Jianmin Wang, MD, PhD¹⁰, Hongbo Hu, PhD^11* and Xiaoxia Hu^7*

¹Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital，Shanghai Jiao Tong University School of Medicine, Shanghai, China
²Center for Hematology and Immunology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Collaborative Innovation Center for Biotherapy, Chengdu, CHN
³Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, Nati, Shanghai, China
⁴The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Shanghai, China
⁵Department of Hematology, Institute of Hematology, Changhai Hospital, Shanghai, CHN
⁶Department of Hematology, Institute of Hematology, Changhai Hospital, Shanghai, China
⁷Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
⁸Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, tianjin, China
⁹State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences &Peking Union Medical College, Tianjin, China
¹⁰Changhai Hospital, Shanghai, China
¹¹Center For Hematology and Immunology, State Key Laboratory of Biotherapy, West C, Chengdu, CHN

Nicoletta Cieri, MD, PhD^1,2,3, Yiren Shao^4*, Kaila Power^2*, Vincent T. Ho, MD^2,3*, Jonathan Stevens^5*, William J. Lane^5*, Haesook T. Kim, PhD⁴, Donna S. Neuberg, ScD⁴, Chip Stewart, PhD^1*, Gad Getz, PhD^1,3,6*, Jerome Ritz, MD^2,3, Robert J. Soiffer, MD^2,3 and Catherine J. Wu, MD^1,2,3*

¹Broad Institute of MIT and Harvard, Cambridge, MA
²Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
³Harvard Medical School, Boston, MA
⁴Department of Data Science, Dana-Farber Cancer Institute, Boston, MA
⁵Brigham and Women's Hospital, Boston, MA
⁶Department of Pathology, Massachusetts General Hospital, Boston, MA