Hartmut Goldschmidt, MD^1,2, Uta Bertsch, MD^3,4*, Ema Pozek^5*, Axel Benner^6*, Roland Fenk, MD, PhD^7*, Britta Besemer, MD^8*, Christine Hanoun^9*, Roland Schroers, MD^10*, Ivana von Metzler, MD^11*, Mathias Hänel, MD¹², Christoph Mann, MD^13*, Lisa Leypoldt, MD^14*, Bernhard Heilmeier^15*, Stefanie Huhn, PhD^16*, Sabine Vogel, PhD^17*, Michael Hundemer, MD^18*, Christof Scheid, MD¹⁹, Igor Wolfgang Blau, MD, PhD^20*, Steffen Luntz, MD^21*, Tobias A.W. Holderried, MD^22*, Karolin Trautmann-Grill, MD^23*, Deniz Gezer, MD^24*, Maika Klaiber-Hakimi^25*, Martin Mueller, MD^26*, Evgenii Shumilov^27*, Wolfgang Knauf, MD^28*, Christian Sebastian Michel, MD^29*, Thomas Geer, MD³⁰, Hendrik Riesenberg^31*, Christoph Lutz^32*, Marc-Steffen Raab^33*, Martin Hoffmann^34*, Katja C. Weisel, MD³⁵, Hans Salwender, MD^36* and Elias K. Mai, MD^37*

¹Internal Medicine V, GMMG - Study Group at University Hospital Heidelberg, Heidelberg, Germany
²National Center for Tumor Diseases (NCT), Heidelberg University Hospital, Heidelberg, Germany
³National Center for Tumor Diseases Heidelberg, Heidelberg, Germany
⁴Internal Medicine V, Hematology, Oncology and Rheumatology, GMMG Studygroup, Heidelberg University Hospital, Heidelberg, Germany
⁵German Cancer Research Center, Heidelberg, DEU
⁶Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany
⁷Department of Haematology, Oncology, and Clinical Immunology, University Hospital Düsseldorf, Düsseldorf, Germany
⁸Department of Internal Medicine II, University Hospital Tübingen, Tübingen, Germany
⁹Department of Hematology and Stem Cell Transplantation, West German Cancer Center and German Cancer consortium (DKTK partner site Essen), University Hospital Essen, University of Duisburg-Essen, Essen, Germany
¹⁰Knappschaftskrankenhaus Bochum, University Hospital Bochum, Bochum, Germany
¹¹Department of Medicine II – Hematology and Oncology, Goethe-University Frankfurt, University Hospital, Frankfurt am Main, Germany
¹²Department of Internal Medicine III, Klinikum Chemnitz, Chemnitz, Germany
¹³Department of Haematology, Oncology and Immunology, Philipps-University Marburg, Marburg, Germany
¹⁴University Medical Center Hamburg Eppendorf, Hamburg, Germany
¹⁵Clinic for Oncology and Hematology, Hospital Barmherzige Brueder Regensburg, Regensburg, Germany, Regensburg, DEU
¹⁶Department of Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany
¹⁷Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany, Heidelberg, Germany
¹⁸Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany
¹⁹Department of Internal Medicine I, University Hospital Cologne, Cologne, Germany
²⁰Medical Clinic, Charité University Medicine Berlin, Berlin, Germany
²¹Coordination Centre for Clinical Trials (KKS), Heidelberg, Germany
²²Department of Hematology, Oncology, Stem Cell Transplantation, Immune and Cell Therapy, Clinical Immunology and Rheumatology, University Hospital Bonn, Bonn, Germany
²³University Hospital Carl Gustav Carus, Dresden, Germany
²⁴Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, DEU
²⁵Clinic for Hematology, Oncology and Palliative Care, Marien Hospital Düsseldorf, Düsseldorf, Germany, Duesseldorf, DEU
²⁶Klinikum Siloah Hannover, Hannover, Germany, Hannover, AL, DEU
²⁷Department of Medicine A, Hematology, Oncology and Pneumology, University Hospital Muenster, Muenster, Germany
²⁸Center for Hematology and Oncology, Bethanien, Frankfurt a.M., Germany, Frankfurt a.M., Germany
²⁹Department of Internal Medicine III, University Hospital Mainz, Mainz, Germany
³⁰Medizinische Klinik Schwäbisch-Hall, Schwabisch Hall, DEU
³¹Hematology / Oncology Center, Bielefeld, Germany, Bielefeld, Germany
³²Hematology / Oncology Center, Koblenz, Germany, Koblenz, Germany
³³Department of Medicine V, Heidelberg Myeloma Center, University Hospital Heidelberg, Heidelberg, Germany
³⁴Medical Clinic A, Clinic Ludwigshafen, Ludwigshafen, Germany, Ludwigshafen, Germany
³⁵Department of Oncology, Hematology and BMT, University Medical Center of Hamburg-Eppendorf, Hamburg, Germany
³⁶Asklepios Tumorzentrum Hamburg, Asklepios Hospital Hamburg Altona and St. Georg, Hamburg, Germany
³⁷Heidelberg Myeloma Center, Department of Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany

Robert Z. Orlowski, MD, PhD¹, Meletios-Athanasios Dimopoulos², Xavier Leleu³, Zhuogang Liu^4*, Tadao Ishida⁵, Roman Hajek, MD, PhD⁶, Ivan Špička^7*, Joanna Romejko-Jarosinska, MD, PhD^8*, Vladimir I. Vorobyev, PhD^9*, Britta Besemer, MD^10*, Sevgi Beşışık, MD^11*, Pawel Robak^12*, Hartmut Goldschmidt, MD¹³, Thomas Martin, MD¹⁴, Mohamad Mohty, MD, PhD¹⁵, Sandrine Macé, PhD^16*, Ercem Kodas, PhD^16*, Christina Tekle^17*, Andrea Shafer^17* and Philippe Moreau, MD, PhD^18*

¹Department of Lymphoma & Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
³Service d'Hématologie et Thérapie Cellulaire, CHU and CIC Inserm 1402, Poitiers, France
⁴Shengjing Hospital of China Medical University, Shenyang, China
⁵Japanese Red Cross Medical Center, Tokyo, Japan
⁶Department of Hemato-Oncology, University Hospital Ostrava and Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic
⁷Charles University and General Hospital in Prague, Prague, Czech Republic
⁸Department of Lymphoid Malignancies, Marie Sklowdoska-Curie National Research Institute of Oncology, Warszawa, Poland
⁹S.P. Botkin Moscow City Clinical Hospital, Moscow, Russian Federation
¹⁰Department of Hematology, Oncology, Immunology and Rheumatology, University Hospital of Tuebingen, Tuebingen, Germany
¹¹Department of Internal Medicine, Istanbul Medical Faculty, Istanbul, Turkey
¹²Department of General Hematology, Copernicus Memorial Hospital, Comprehensive Cancer Center and Traumatology, Łódź, Poland
¹³Internal Medicine V, Hematology, Oncology and Rheumatology, GMMG Studygroup, Heidelberg University Hospital, Heidelberg, Germany
¹⁴Department of Hematology, University of California at San Francisco, San Francisco, CA
¹⁵Department of Hematology, Hôpital Saint-Antoine, Sorbonne University and INSERM, Paris, France
¹⁶Sanofi, R&D, Vitry-sur-Seine, France
¹⁷Sanofi, Cambridge, MA
¹⁸University Hospital Hôtel-Dieu, Nantes, France

Charlotte Pawlyn, PhD^1,2, Faith E Davies, MD³, Martin F Kaiser, MD, FRCP, FRCPath^1,2, Ruth M de Tute, MSc, PhD, FRCPath^4*, Heather McIntyre^5*, Jeanine Richards^5*, Sharon Jackson^5*, Elizabeth Hodson^5*, Anna Hockaday^5*, Catherine Olivier^5*, John R Jones^6,7,8*, Matthew W. Jenner^9*, Gordon Cook, PhD, DSc^10*, Walter Martin Gregory, PhD^5*, Mark Drayson^11*, Roger G Owen, MD, MRCP, FRCPath^4*, Gareth Morgan, M.D., Ph.D.^3*, David A. Cairns, PhD^10* and Graham Jackson, MD^12*

¹The Institute of Cancer Research, London, United Kingdom
²The Royal Marsden NHS Foundation Trust, London, United Kingdom
³Perlmutter Cancer Center, Multiple Myeloma Research Program, NYU Langone Health, New York, NY
⁴HMDS, Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
⁵Leeds Cancer Research UK Clinical Trials Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, United Kingdom
⁶Kings College Hospital, London, United Kingdom
⁷Brighton and Sussex Medical School, Brighton, United Kingdom
⁸East Sussex NHS Trust, Eastbourne, United Kingdom
⁹University Hospital Southampton, Southampton, United Kingdom
¹⁰Cancer Research UK Clinical Trials Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, United Kingdom
¹¹University of Birmingham, Institute of Immunology and Immunotherapy, Birmingham, United Kingdom
¹²University of Newcastle, Department of Haematology, Newcastle, United Kingdom

Vania Hungria, MD, PhD¹, Pawel Robak, MD, PhD^2*, Marek Hus, MD, PhD^3*, Vera Zherebtsova, MD^4*, Christopher Ward, MD, PhD^5*, Phoebe Joy Ho, MBBS⁶, Roman Hajek, MD, PhD⁷, Kihyun Kim, MD^8*, Sebastian Grosicki, MD, PhD^9*, Hanlon Sia, MBBS FRACP FRCPA^10*, Adam Bryant, MBBS, PhD¹¹, Marcelo Pitombeira de Lacerda, MD, PhD^12*, Gracia Aparecida Martinez, MD, PhD^13*, Anna Maria Sureda Balarí, MD, PhD¹⁴, Irwindeep Sandhu, MD¹⁵, Claudio Cerchione, MD¹⁶, Peter Ganly, BMBCh, PhD¹⁷, Meletios Dimopoulos, MD¹⁸, Chengcheng Fu^19*, Mamta Garg, MD^20*, Al-Ola Abdallah, MD²¹, Moshe E Gatt, MD²², Albert Oriol, MD^23*, Michele Cavo, MD^24*, Robert Rifkin, MD, FACP²⁵, Tomoaki Fujisaki, MD, PhD^26*, Michał Mielnik, MD^3*, Nick Pirooz, MHA^27*, Joe Lee, PhD^28*, Astrid McKeown, PhD^29*, Rachel Rogers, MS^27*, Hena Baig, BS^30*, Lydia Eccersley, MBBS, MRCP, FRCPath, PhD^28*, Sumita Roy-Ghanta, MD^27* and Maria Victoria Mateos, MD, PhD³¹

¹Clinica São Germano, São Paulo, Brazil
²Medical University of Lodz, Lodz, Poland
³Medical University of Lublin, Lublin, Poland
⁴Gorodskaya Klinicheskaya Bol’nitsa Im. S.p. Botkina, Moscow, Russian Federation
⁵Royal North Shore Hospital, Sydney, NSW, Australia
⁶Royal Prince Alfred Hospital, Camperdown, NSW, Australia
⁷University Hospital Ostrava and University of Ostrava, Ostrava, Czech Republic
⁸Sungkyunkwan University, Samsung Medical Center, Seoul, Korea, Republic of (South)
⁹Medical University of Silesia, Katowice, Poland
¹⁰Pindara Private Hospital, Gold Coast, Australia
¹¹Liverpool Hospital, Sydney, Australia
¹²Universidade da Região de Joinville (Univille), Joinville, Santa Catarina, Brazil
¹³Hospital das Clínicas and Instituto do Câncer do Estado de São Paulo, Universidade de São Paulo, São Paulo, Brazil
¹⁴Institut Català d'Oncologia-L'Hospitalet L.-Barcelona, Barcelona, Spain
¹⁵Cross Cancer Institute, Edmonton, AB, Canada
¹⁶Hematology Unit, Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST IRCCS, Meldola (FC), Italy
¹⁷Christchurch Hospital, Christchurch, New Zealand
¹⁸National and Kapodistrian University of Athens, Athens, Greece
¹⁹The First Affiliated Hospital of Soochow University, Suzhou, China
²⁰University Hospitals of Leicester NHS Trust, Leicester, United Kingdom
²¹University of Kansas Cancer Center, Fairway, KS
²²Department of Haematology, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel
²³Institut Català d’Oncologia and Josep Carreras Research Institute, Hospital Germans Trias i Pujol, Badalona, Spain
²⁴Istituto di Ematologia "Seràgnoli", IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
²⁵Rocky Mountain Cancer Centers - Denver – Midtown, Denver, CO
²⁶Matsuyama Red Cross Hospital, Matsuyama, Japan
²⁷GSK, Upper Providence, PA
²⁸GSK, London, United Kingdom
²⁹GSK, Stevenage, United Kingdom
³⁰GSK, Mississauga, Ontario, CAN
³¹Hospital Universitario de Salamanca/IBSAL/CIC/Ciberonc, Salamanca, Spain

Meletios-Athanasios Dimopoulos¹, Peter M. Voorhees, MD², Fredrik Schjesvold, MD, PhD³, Yael C. Cohen⁴, Vania Hungria, MD, PhD⁵, Irwindeep Sandhu, MD^6*, Jindriska Lindsay, FRCP FRCPath^7*, Ross Ian Baker, MBBS, BSc, FRACP, FRCPA⁸, Kenshi Suzuki, MD, PhD⁹, Hiroshi Kosugi, MD^10*, Mark-David Levin¹¹, Meral Beksac^12*, Keith Stockerl-Goldstein^13*, Albert Oriol^14*, Gabor Mikala^15*, Gonzalo Martin Garate, MD^16*, Koen Theunissen^17*, Ivan Spicka, CSc^18*, Anne K. Mylin^19*, Sara Bringhen, MD, PhD²⁰, Katarina Uttervall^21*, Bartosz Michal Pula, MD, PhD^22*, Eva Medvedova, MD^23*, Andrew J. Cowan, MD^24*, Philippe Moreau, MD, PhD^25*, Maria-Victoria Mateos, MD, PhD²⁶, Hartmut Goldschmidt, MD²⁷, Tahamtan Ahmadi, MD, PhD^28*, Linlin Sha, PhD^29*, Els Rousseau^30*, Liang Li^29*, Robyn M. Dennis^31*, Robin Carson, MD³² and Vincent Rajkumar, MD^33*

¹National and Kapodistrian University of Athens, Alexandra General Hospital, Athens, Greece
²Levine Cancer Institute, Atrium Health Wake Forest University School of Medicine, Charlotte, NC
³Oslo Myeloma Center, Department of Hematology, Oslo University Hospital, Oslo, Norway
⁴Tel-Aviv Sourasky (Ichilov) Medical Center, and Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⁵Clinica São Germano, São Paulo, Brazil
⁶University of Alberta, Cross Cancer Institute, Edmonton, AB, Canada
⁷Kent and Canterbury Hospital, Kent, United Kingdom
⁸Perth Blood Institute, Murdoch University, Perth, Australia
⁹Japanese Red Cross Medical Center, Tokyo, Japan
¹⁰Ogaki Municipal Hospital, Ogaki City, Japan
¹¹Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, Netherlands
¹²Ankara Liv Hospital, Istinye University, Ankara, Turkey
¹³Washington University School of Medicine, St. Louis, MO
¹⁴Institut Català d'Oncologia and Institut Josep Carreras, Hospital Germans Trias i Pujol, Barcelona, Spain
¹⁵South Pest Central Hospital, National Institute for Hematology and Infectious Diseases, Budapest, Hungary
¹⁶Department of Hematology, Hospital Alemán, Buenos Aires, Argentina
¹⁷Jessa Hospital, Hasselt, Belgium
¹⁸Charles University and General Hospital, Prague, Czech Republic
¹⁹Department of Hematology, Rigshospitalet, Copenhagen, Denmark
²⁰SSD Clinical Trials in Oncol-ematologia e Mieloma Multiplo, AOU Città della Salute e della Scienza di Torino, Torino, Italy
²¹Hematology Medical Unit, Karolinska University Hospital, Stockholm, Sweden
²²Institute of Hematology and Transfusion Medicine, Warszawa, Poland
²³Knight Cancer Institute, Oregon Health & Science University, Portland, OR
²⁴University of Washington and Fred Hutchinson Cancer Center, Seattle, WA
²⁵University Hospital Hôtel-Dieu, Nantes, France
²⁶University Hospital of Salamanca/IBSAL/Cancer Research Center-IBMCC (USAL-CSIC), Salamanca, Spain
²⁷GMMG-Study Group at University Hospital Heidelberg, Internal Medicine V, Heidelberg, Germany
²⁸Genmab, Plainsboro, NJ
²⁹Janssen Research & Development, LLC, Shanghai, China
³⁰Janssen Research & Development, Beerse, Belgium
³¹Janssen Research & Development, LLC, Raritan, NJ
³²Janssen Research & Development, LLC, Spring House, PA
³³Division of Hematology, Mayo Clinic, Rochester, MN

Salomon Manier, MD, PhD¹, Jérome Lambert, MD, PhD^2*, Cyrille Hulin, MD^3*, Kamel Laribi, MD^4*, Carla Araujo^5*, Gian Matteo Pica, MD^6*, Cyrille Touzeau, MD, PhD^7*, Pascal Godmer^8*, Bohrane Slama^9*, Lionel Karlin^10*, Frederique Orsini Piocelle, MD^11*, Mamoun Dib^12*, Magaret Macro, MD^13*, Laurence Sanhes, MD^14*, Lydia Montes, MD^15*, Abderrazak El Yamani, MD^16*, Mourad Tiab, MD^17*, Reza Tabrizi^18*, Laurent Garderet, MD, PhD^19*, Bruno Royer, MD^20*, Benoit Bareau^21*, Aurore Perrot, MD, PhD²², Jean Yves Mary^23*, Jill Corre, PharmD, PhD^24*, Herve Avet Loiseau, MD, PhD²⁵, Philippe Moreau, MD, PhD^26*, Xavier Leleu²⁷ and Thierry Facon, MD²⁸

¹Lille University Hospital, Lille, France
²Biostatistics and Medical Information Department, Saint Louis University Hospital, AP-HP, Université Paris Cité, Paris, FRA
³Hôpital Haut Lévêque, University Hospital, Pessac, France
⁴Hematology Department, Le Mans Hospital, Le Mans, France
⁵CH Bayonne, Bayonne, FRA
⁶Département d'Hématologie, CH Chambery, Chambéry, France
⁷Centre Hospitalier Universitaire de Nantes, Nantes, France
⁸CH Vannes, Vannes, FRA
⁹Service d'onco-hématologie, Centre Hospitalier Général d'Avignon, Avignon, FRA
¹⁰Department of Hematology, Lyon Sud Hospital, Pierre Benite, France
¹¹hematology, ANNECY Hospital, annecy, France
¹²Chu Angers, Angers, FRA
¹³CHU de Caen, Caen, France
¹⁴Centre Hospitalier Perpignan, Perpignan, France
¹⁵CHU Amiens-Picardie, Amiens, France
¹⁶Centre Hospitalier de Blois, Blois, FRA
¹⁷Centre Hospitalier Departemental, La Roche Sur Yon Cedex 9, FRA
¹⁸CH Mont de Marsan, Mont De Marsan, FRA
¹⁹Hôpital la pitié salpetriere, Paris, FRA
²⁰Department of Immuno-hematology, Hôpital Saint Louis, APHP, Paris, France
²¹Cabinet Medicale, Rennes, FRA
²²Hématologie, Institut Universitaire du Cancer de Toulouse (IUCT) Oncopole, Toulouse, France
²³INSERM, Paris, FRA
²⁴Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France
²⁵Unité Génomique du Myélome, University Hospital Toulouse, IUCT Oncopole, Toulouse, France
²⁶Hematology, University Hospital of Nantes, Nantes, France
²⁷Poitiers University Hospital, Poitiers, France
²⁸University of Lille, CHU Lille, Service des Maladies du Sang, Lille, France