Boya Wang, PhD^1,2, George W. Wright, PhD^3*, Julius C. Enssle, MD^4*, Yandan Yang, PhD^1*, Da Wei Huang, MD^1*, Xin Yu^1*, Arvin E Ruiz^5*, James D. Phelan, PhD^1*, Arthur L Shaffer III, PhD^6*, Thomas Oellerich, MD^4*, Giorgio Inghirami, MD^5* and Louis M. Staudt, MD, PhD⁷

¹Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD
²University of North Carolina at Chapel Hill, Chapel Hill, NC
³Biometric Research Program, National Cancer Institute, National Institutes of Health, Bethesda, MD
⁴Goethe-University Frankfurt, University Hospital, Department of Medicine II - Hematology and Oncology, Frankfurt am Main, Germany
⁵Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY
⁶AstraZeneca, Gaithersburg, MD
⁷Metabolism Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD

Zhijuan Lin, MD^1*, Xingxing Yu^2*, Yan Hong^2*, Long Liu^2*, Zhifeng Li^2*, Jie Zha^2* and Bing Xu³

¹Department of Hematology, The First Affiliated Hospital of Xiamen University and Institute of Hematology, School of Medicine, Xiamen University, Xiamen, China
²Department of Hematology, The First Affiliated Hospital of Xiamen University and Institute of Hematology, School of Medicine, Xiamen University, Xiamen, Fujian, China
³The First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China

Stefano Casola, MD, PhD^1,2, Paola Sindaco, MD³, Silvia Lonardi^4*, Gabriele Varano, PhD⁵, Ilaria Pietrini^6*, Gaia Morello^7*, Piera Balzarini^8*, Hadas Neuman^9*, Filippo Vit, MSc^10*, Giorgio Bertolazzi^11*, Hiroshi Arima, MD, PhD^6,12*, Marco Chiarini, PhD^13*, Luisa Lorenzi^8*, Vilma Pellegrini^14*, Sabrina Giampaolo^6*, Daniel Garzon^6*, Cecilia Ranise^6*, Mattia Bugatti^15*, Chiara Pagani, MD^16*, Rosa Daffini, MD^17*, Federica Mainoldi^6*, Viveka Selvarasa^6*, Anojan Sivacegaram^6*, Henry Yang^18*, Li Ying^18*, Valeria Cancila^7*, Raoul Bonnal^19*, Euplio Visco^20*, Cristina Lopez Gonzalez^21,22*, Pasquale Capaccio^23*, Andrés José María Ferreri, MD²⁴, Alessandra Tucci, MD²⁵, Antonello Cabras^26*, Giancarlo Pruneri, MD^27*, Arianna Di Napoli, MD^28*, Reiner Siebert, PhD^29*, Riccardo Bomben, PhD^30*, Brunangelo Falini³¹, Marco Pizzi^32*, Joo Y. Song, MD³³, Wing Chung Chan, MD³⁴, Maurilio Ponzoni, MD³⁵, Ramit Mehr^36*, Claudio Tripodo^11* and Fabio Facchetti^37*

¹IFOM-ETS, Milan, Italy
²Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
³Inselspital, Universitätsspital Bern, Department of Hematology and Central Hematology Laboratory., Bern, Switzerland
⁴Spedali Civili Brescia, Volta Mantovana, MN, ITA
⁵IFOM-ETS, Milano, Italy
⁶IFOM ETS-The AIRC Institute of Molecular Oncology, Milano, Italy
⁷University of Palermo, Palermo, ITA
⁸Spedali Civili Di Brescia, Brescia, ITA
⁹Bar Ilan University, The Mina and Everard Goodman Faculty of Life Sciences, Ramat Gan, Israel
¹⁰Clinical and Experimental Onco-Haematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy, Italy
¹¹University of Palermo, Palermo, Italy
¹²Kyoto University, Kyoto, JPN
¹³Clinical Chemistry Laboratory, Diagnostic Department, ASST Spedali Civili Di Brescia, Brescia, Italy
¹⁴Pathology unit; University of Brescia, Spedali Civili, Department of Molecular and Translational Medicine, Brescia, Italy, Brescia, Italy
¹⁵BRESCIA UNIVERSITY, BRESCIA, ITA
¹⁶ASST Spedali Civili di Brescia, Brescia, Italy
¹⁷Hematology, ASST Spedali Civili di Brescia, Brescia, Italy
¹⁸Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore
¹⁹The AIRC Institute of Molecular Oncology (IFOM), Milan, Italy
²⁰Pathology unit, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milano, Italy
²¹University Medical Center JGU Mainz, Mainz, DEU
²²Hematopathology Unit, Hospital Clínic Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS),, Barcelona, Spain
²³University of Milan, Milano, Italy
²⁴Unit of Lymphoid Malignancies, Department of Onco-Haematology, IRCCS San Raffaele Scientific Institute, Milano, Italy
²⁵UOC Ematologia, Brescia, Italy
²⁶Istituto Nazionale Tumori, Milan, Mi, ITA
²⁷Istituto Nazionale dei Tumori Foundation, Milan, Italy
²⁸Sapienza University of Rome-sant'Andrea Hospital, Rome, ITA
²⁹Institute of Human Genetics, Ulm University and Ulm University Medical Center, Ulm, Ulm, DEU
³⁰Clinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy
³¹Institute of Hematology and Center for Hemato-Oncology Research, University and Hospital of Perugia, Perugia, Italy
³²University of Padua, Padova, ITA
³³Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA
³⁴Department of Pathology, City of Hope National Medical Center, Duarte, CA
³⁵Pathology Unit, IRCCS San Raffaele Scientific Institute and Università Vita-Salute San Raffaele, Milan, Italy
³⁶Bar-Ilan University, Ramat-Gan, ISR
³⁷University of Brescia, Brescia, ITA

Takeshi Sugio, MD, PhD^1*, Monica Nesselbush^2*, Navika Shukla, MD¹, Andrea Garofalo, BS, BA¹, Jurik A. Mutter, PhD^3*, Mohammad Shahrokh Esfahani, PhD^4*, Stefan K. Alig, MD¹, Shuyu Shi⁵, Troy Noordenbos^1*, Mark P. Hamilton, MD, PhD⁶, Cedric Rossi, MD, PhD⁷, Feng Tian, PhD^1*, Chih Long Liu, PhD^1*, Mari Olsen, BS^1*, Xiaoman Kang, BS^8*, David A Russler-Germain, MD, PhD⁹, Steven Horwitz, MD¹⁰, Koji Kato, MD, PhD¹¹, Ayumu Ito, MD, PhD^12*, Makoto Yamagishi, PhD^13*, Takahiro Fukuda^12*, Koichi Akashi, MD, PhD^14*, Kaoru Uchimaru, MD, PhD^15*, Michael S. Khodadoust, MD, PhD¹⁶, Maximilian Diehn, MD, PhD^17*, Neha Mehta-Shah, MD¹⁸ and Ash A. Alizadeh, MD, PhD¹

¹Department of Medicine, Divisions of Oncology and Hematology, Stanford University, Stanford, CA
²Program in Cancer Biology, Stanford School of Medicine, Stanford, CA
³Divisions of Oncology and Hematology, Stanford University, Stanford, CA
⁴Department of Radiation Oncology, Stanford University, Stanford, CA
⁵Dept. of Bioengineering, Schools of Engineering and Medicine, Stanford, CA
⁶Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University School of Medicine, Palo Alto, CA
⁷CHU Dijon, DIJON, France
⁸Department of Medicine, Division of Oncology, Stanford University, Stanford, CA
⁹Siteman Cancer Center, Division of Oncology, Washington University School of Medicine, Saint Louis, MO
¹⁰Lymphoma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
¹¹Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medicine, Fukuoka, Japan
¹²Department of Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital, Tokyo, Japan
¹³Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, JPN
¹⁴Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
¹⁵Laboratory of Tumor Cell Biology, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan
¹⁶Departments of Dermatology and Medicine - Oncology, Stanford University School of Medicine, Stanford, CA
¹⁷Department of Radiation Oncology, Stanford University Medical Center, Stanford, CA
¹⁸Siteman Cancer Center, Washington University School of Medicine, Olivette, MO

Ranjit Nair, MD^1*, Daniela E. Duenas, MD^2*, Jingjing Liu^3*, Rishab Prakash, BS^4*, Chen Zhou^5*, Ayse A Koksoy, MD, PhD^3*, Jie Xu, MD PhD^6*, Salome A McAllen^3*, Luis Malpica, MD^4*, Raja Luthra, Ph.D^7*, Francisco Vega, MD, PhD⁸, Roberto N. Miranda, MD^6*, Jianhua Zhang, PhD^9*, L. Jeffrey Medeiros, MD⁶, Cara L Haymaker, PhD^2*, Christopher R. Flowers, MD, MS⁴, Sattva S. Neelapu, MD⁴ and Swami P. Iyer, MD⁴

¹The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX
³University of Texas MD Anderson Cancer Center, Houston
⁴Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
⁵Penn State University, State College, PA
⁶Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
⁷Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
⁸MD Anderson Cancer Center , Houston, TX
⁹Departments of Genomic Medicine, M. D. Anderson Cancer Center, Houston, TX

Dylan T. Jochum, BS^1,2, Alyssa Bouska, PhD^1*, Sunandini Sharma, PhD^1*, Suchita Vishwakarma, M.Pharm^3*, Catalina Amador, MD^4*, Waseem Gul Lone, PhD^1*, Ab Rauf Shah, Ph.D^1*, Abdul Rouf Mir, PhD^1*, Mahfuza Afroz Soma, MS^1*, Syed Mohsin Mehmood, MBBS^1*, Zaina Nasser^5*, Andrew L. Feldman, MD⁶, Timothy C. Greiner, MS, MD^1*, Julie M. Vose, MD, MBA⁷, James R. Cook, MD, PhD⁸, Sarah L. Ondrejka, DO⁸, Elaine S. Jaffe, MD^9*, Andreas Rosenwald^10*, German Ott, MD^11*, Phillipp W. Raess, MD, PhD^12*, Kerry J. Savage, MD, MSc¹³, Graham W. Slack, MD^14*, David W. Scott, MBChB, PhD¹⁵, Joo Y Song, MD^16*, Elias Campo, MD, PhD^17,18*, Louis M. Staudt, MD, PhD¹⁹, Lisa M. Rimsza, MD²⁰, Dennis D Weisenburger, MD^1*, Giorgio Inghirami, MD^21*, Amar Natarajan, PhD^2,3*, Javeed Iqbal, PhD, MSc^1* and Wing Chung Chan, MD¹⁶

¹Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE
²Eppley Institute for Cancer Research, University of Nebraska Medical Center, Omaha, NE
³Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE
⁴Division of Hematopathology, University of Miami, Miami, FL
⁵College of Arts and Sciences, University of Nebraska, Lincoln, NE
⁶Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
⁷Department of Hematology and Oncology, University of Nebraska Medical Center, Omaha, NE
⁸Department of Pathology and Laboratory Medicine, Cleveland Clinic, Cleveland, OH
⁹Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, MD
¹⁰Institute of Pathology, University Hospital of Wuerzburg, and Comprehensive Cancer Center Mainfranken, Würzburg, Germany
¹¹Department of Clinical Pathology, Robert-Bosch-Krankenhaus, and Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany
¹²Department of Pathology and Laboratory Medicine, Oregon Health & Science University, Portland, OR
¹³BC Cancer, Vancouver, BC, Canada
¹⁴Centre for Lymphoid Cancer, BC Cancer, Vancouver, BC, Canada
¹⁵Centre for Lymphoid Cancer, British Columbia Cancer, Vancouver, BC, Canada
¹⁶Department of Pathology, City of Hope National Medical Center, Duarte, CA
¹⁷Hematopathology Unit, Hospital Clinic, Barcelona, Spain
¹⁸Institute of Biomedical Research August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain
¹⁹Metabolism Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD
²⁰Department of Laboratory Medicine and Pathology, Mayo Clinic, Scottsdale, AZ
²¹Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY