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Phylogenetic Reconstruction of Hematopoiesis

PhD Trainee  Ticketed Session
Sponsor: Scientific
Program: Spotlight Sessions
Hematology Disease Topics & Pathways:
Genomics, Biological Processes, Technology and Procedures
Monday, December 9, 2024: 10:30 AM-11:45 AM
Room 7 (San Diego Convention Center)
Co-chairs:
Jyoti Nangalia, MBBChir, Wellcome Sanger Institute and Charles Gawad, MD, Stanford University
Disclosures:
Nangalia: Astra Zeneca: Consultancy, Speakers Bureau; Bioskryb: Consultancy.

Hematopoiesis is a complex and highly regulated process that has been increasingly understood through advances in genetics, epigenetics, and single-cell genomics technologies. Recent work has focused on increasingly nuanced and detailed phylogenies of hematopoietic cells in normal and aged individuals, and multidimensional understanding of phylogenetic trees of stem cells, progenitors, and mature progeny. Genomics, epigenetics, advanced computational analyses, large scale datasets, and single-cell approaches are all integral in this effort. This session will present some of the latest advances in the field and serve to educate the audience of how these may inform our understanding of physiological and pathological mechanisms in hematopoiesis.

Jyoti Nangalia, MBBChir

Wellcome Sanger Institute, Hinxton, United Kingdom

See more of: Spotlight Sessions