Peripheral T-cell lymphoma (PTCL) represents a group of heterogeneous and aggressive non-Hodgkin lymphomas with generally poor prognosis. Despite advances in understanding the underlying biology, treatment outcomes have remained suboptimal. This symposium, supported by Acrotech, and provided by the University of Texas MD Anderson Cancer Center with MD Education, will explore groundbreaking therapies and the shifting paradigm in PTCL treatment. Renowned experts will dissect the complexity of PTCL biology, discuss innovative therapeutic strategies, and address the challenges faced in clinical practice. Presentations will include insights into nodal T-cell lymphoma epigenetics, CAR-T cell therapy applications, and novel approaches for rare PTCL subtypes. This educational event promises to answer pivotal questions in PTCL management, focusing on improving patient outcomes and quality of life. With a blend of didactic sessions, interactive panels, and case studies, attendees will be at the forefront of translating emerging research into transformative patient care.