-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

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An Interactive Case-based Review of Chronic Lymphocytic Leukemia: Experts Explore the Latest Evidence and Guideline Updates

Sponsor: educational grants from AstraZeneca, BeiGene, and Lilly. Provided by the National Comprehensive Cancer Network in collaboration with Clinical Care Options.
Program: Friday Satellite Symposia
Hematology Disease Topics & Pathways:
Lymphoid Leukemias, Combination therapy, Antibody Therapy, CLL, Chimeric Antigen Receptor (CAR)-T Cell Therapies, Diseases, Therapy sequence, Treatment Considerations, Biological therapies, Lymphoid Malignancies, Technology and Procedures, Molecular testing
Friday, December 6, 2024: 7:00 AM-10:00 AM
Grand Hall C (Manchester Grand Hyatt San Diego)
Chair:
Brian T. Hill, MD, PhD, The Cleveland Clinic Foundation
Disclosures:
Hill: Genentech: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Pharmacyclics: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; AstraZeneca: Consultancy, Honoraria, Research Funding; Abbvie: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; BMS: Consultancy, Honoraria, Research Funding; Beigene: Consultancy, Honoraria, Research Funding.
Speakers:
Sameer A. Parikh, MBBS, Mayo Clinic and Danielle M. Brander, MD, Duke University
Disclosures:
Parikh: Pharmacyclics: Consultancy; Merck: Consultancy, Research Funding; Janssen: Consultancy, Research Funding; MingSight: Consultancy; AbbVie: Consultancy; Genentech: Consultancy, Research Funding; AstraZeneca: Consultancy, Research Funding; Kite: Consultancy; Novalgen Limited: Consultancy; BeiGene: Consultancy; Amgen: Consultancy. Brander: Nurix: Other: site PI clinical trial (grant paid to institution); NeWave: Other: site PI clinical trial (grant paid to institution); Juno/Celegene/BMS: Other: site PI clinical trial (grant paid to institution); Genentech: Consultancy, Other: site PI clinical trial (grant paid to institution); DTRM: Other: site PI clinical trial (grant paid to institution); Catapult: Other: site PI clinical trial (grant paid to institution); BeiGene: Consultancy, Other: site PI clinical trial (grant paid to institution); AstraZeneca/Acereta: Other: site PI clinical trial (grant paid to institution); ArQule/Merck: Other: site PI clinical trial (grant paid to institution); AbbVie: Consultancy, Other: site PI clinical trial (grant paid to institution); Pharmacyclics: Consultancy, Other: site PI clinical trial (grant paid to institution); TG therapeutics: Other: site PI clinical trial (grant paid to institution); BMS: Other.

Recent advancements in CLL management include evolving treatment strategies, featuring novel targeted therapies and updated clinical guidelines. The NCCN and CCO are proud to present this interactive opportunity to engage with leading experts to discuss the latest evidence and work through challenging cases. Indeed, this satellite symposium is not just a passive learning experience, but an interactive platform for healthcare professionals to stay fully informed and be equipped to apply the latest treatment advances in CLL. This event delivers an in-depth review of the most recent NCCN Guideline updates and innovative clinical approaches, highlighted through immersive case-based discussions. Attendees will glean critical insights into optimizing treatment strategies, fortified by expert recommendations and comprehensive clinical data. The symposium also provides invaluable resources, including NCCN patient handouts, detailed guideline slides, a review of the 2025 algorithm, and interactive Q&A sessions for direct engagement with the distinguished panel.