This symposium aims to guide the audience through the common challenges faced by mid-career hematologists. Some examples of unique challenges for mid-career hematologists include negotiating the first leadership position, principles of leadership, promotion, strategies for managing individuals and teams, conflict management, setting up a successful research program, time management, funding beyond career development awards, performance and compensation metrics, self-care and opportunities to contribute to the Society’s mission. Speakers will include a diverse pool of successful physicians and scientists from academia, regulatory agencies, and the pharmaceutical industry. It is envisioned that this educational session will be organized by a steering committee of Society members who will identify a longitudinal curriculum for the session and speakers and topics.