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Curative Therapies for Sickle Cell Disease: Option for Some but Not Quite All

Sponsor: Education
Program: Spotlight Sessions
Hematology Disease Topics & Pathways:
Sickle Cell Disease, Hemoglobinopathies, Diversity, Equity, and Inclusion (DEI), Diseases, Gene Therapy, Treatment Considerations, Biological therapies, Transplantation (Allogeneic and Autologous)
Sunday, December 8, 2024: 4:30 PM-5:45 PM
Room 30 (San Diego Convention Center)
Chair:
Kenneth I. Ataga, MD, University of Tennessee Health Science Center
Disclosures:
Ataga: GSK: Consultancy, Honoraria; Hillhurst Biopharmaceuticals: Consultancy, Honoraria; Novartis: Honoraria; Novo Nordisk: Research Funding; Sanofi: Consultancy; Vertex: Membership on an entity's Board of Directors or advisory committees; Vitalant: Membership on an entity's Board of Directors or advisory committees; Forma Therapeutics: Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Agios Pharmaceuticals: Honoraria, Membership on an entity's Board of Directors or advisory committees.
Despite substantial improvements in care, individuals with sickle cell disease continue to experience substantial morbidity and a shortened life expectancy. With recent advances in the development of curative therapies, including allogeneic stem cell transplantation and gene therapy, it is important to identify barriers to accessing these treatments and adequately define suitable candidates for curative therapies.

In this session, Dr. Santosh Saraf will review the current guidelines for curative therapies, discuss the potential benefits and risks of the different curative therapies, and provide insight on when to refer patients for curative therapy.

In the second presentation, Dr. Payal Desai will discuss the various barriers to accessing curative therapies as well as the need for development of an integrated care approach.

Santosh L. Saraf, MD

University of Illinois Chicago, Chicago, IL

Payal Desai, MD

Wake Forest University, Charlotte, NC; Levine Cancer Institute, Department of Hematology, Atrium Health, Charlotte, NC

See more of: Spotlight Sessions