Session: 900. Health Services and Quality Improvement: Hemoglobinopathies: Poster II
Hematology Disease Topics & Pathways:
Research, Sickle Cell Disease, Clinical Practice (Health Services and Quality), Clinical Research, Hemoglobinopathies, Diseases
Methods: We conducted semi-structured interviews with health care team members at 3 sites with varying levels of SNAP implementation: Boston Medical Center (BMC, extensive SNAP use), Children’s Medical Center Dallas (CMCD, limited SNAP use), and Children’s Hospital Pittsburgh (CHP, no SNAP use) about their experiences with and/or perceptions of SNAP. Interviews and a priori codes for the preliminary codebook were guided by the Promoting Action Research on Implementation in Health Services (PARiHS) framework using the Evidence, Context, and Facilitation constructs. Interview transcripts were double coded by three team members using NVivo 12. The codebook was refined until consensus was reached. Team members independently reviewed data to identify preliminary themes and subsequently consolidated themes as a group. Here we present unit- and institutional-level contextual factors, facilitators, and barriers to implementation of SNAP in hospitalized patients with SCD.
Results: Interviews were completed with 29 participants (BMC, n=11, CMCD, n=6, CHP, n=12) until thematic saturation was reached, including: physicians (hospitalists, hematologists, and pulmonologists), nurses, respiratory therapists (RT), child life specialists, psychologists, and clinical leadership. Themes included: 1) Communication among the different clinical staff involved is critical for successful implementation of SNAP. 2) Nurses are key to implementation success, including daytime nurses because many patients with SCD will sleep during the day, and this can help with BiPAP acclimatization. 3) Multidisciplinary support to facilitate daytime BiPAP trials would alleviate some of the burden on overnight nurses, and aid both implementation and patient acceptability. Integration of RT and Child Life is helpful in this process. 4) Specific institutional facilitators and barriers impact implementation, including unit size, whether patients with SCD are admitted to a specific unit, staffing levels, equipment availability, buy-in from leadership, and culture of innovation.
Conclusions/Future directions: Members of health care teams at 3 sites perceive that optimizing communication among clinical team members, improving integration of RT and child life, and incorporating day shift team members into the implementation of SNAP would improve success. Each institution has its own specific and distinct facilitators and barriers to implementation, and strategies will need to adapt to those unique features. These data offer important insights as we develop a protocol for a multi-center hybrid effectiveness/implementation trial of SNAP for hospitalized children with SCD.
Disclosures: Klings: CSL Behring: Consultancy, Membership on an entity's Board of Directors or advisory committees; Pfizer: Consultancy, Membership on an entity's Board of Directors or advisory committees; United Therapeutics: Research Funding; Novartis: Research Funding; Novo Nordisk: Consultancy, Membership on an entity's Board of Directors or advisory committees, Research Funding. Cohen: Sanofi: Other: Member of an independent data safety monitoring board for a clinical trial unrelated to any hematologic condition.
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