Disclosures: Konopleva: AbbVie: Consultancy, Membership on an entity's Board of Directors or advisory committees, Other: clinical trials, Research Funding; Vincerx: Consultancy; Servier: Speakers Bureau; Janssen: Consultancy, Other: clinical trials; Curis: Consultancy; Klondike Biopharma: Research Funding; Syndax: Membership on an entity's Board of Directors or advisory committees; Menarini Group: Consultancy, Membership on an entity's Board of Directors or advisory committees; Adaptive: Consultancy; Intellisphere: Speakers Bureau; Dark Blue Therapeutics: Membership on an entity's Board of Directors or advisory committees; MEI Pharma: Consultancy, Membership on an entity's Board of Directors or advisory committees; Legend Biotech: Membership on an entity's Board of Directors or advisory committees; Novartis: Membership on an entity's Board of Directors or advisory committees; Auxenion GmbH: Membership on an entity's Board of Directors or advisory committees; Sanofi Aventis: Consultancy.