Aino Hakkinen^1,2,3*, Jani Huuhtanen, M.D.^1,2,4,5*, Sofie Lundgren, M.D.^1,2,4*, Riitta Niittyvuopio, M.D., Ph.D.^6*, Harri Lähdesmäki, Ph.D.^5*, Mikko A. I. Keränen, M.D., Ph.D.^1,2,4*, Mikko Myllymäki, M.D., Ph.D.^1,2,4 and Satu Mustjoki, MD, PhD^1,2,4

¹Translational Immunology Research Program and Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland
²Hematology Research Unit Helsinki, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland
³iCAN Digital Precision Cancer Medicine Flagship, Helsinki, AL, Finland
⁴iCAN Digital Precision Cancer Medicine Flagship, Helsinki, Finland
⁵Department of Computer Science, Aalto University, Espoo, Finland
⁶Helsinki University Hospital Comprehensive Cancer Center, Stem Cell Transplantation Unit, Helsinki, Finland

Ying WANG^1*, Alicia Huaze Li^2*, Ruqayyah sanders-Braggs^1*, Yan Zhou^3*, Mimi Chen, PhD^4*, Tien Bui^1*, Hongfa Zhu^5*, Jonathan Soboloff^6*, John Elrod^7*, Elizabeth O Hexner, MD, MSTR⁸ and Yi Zhang, MD, PhD⁴

¹Center for Discovery and Innovation, Hackensack University Medical Center, Nutley
²2Fels Institute for Cancer Research and Molecular Biology, Temple University, Philadelphia
³Fox Chase Cancer Center, Temple University, Philadelphia
⁴Center for Discovery and Innovation, Hackensack University Medical Center, Nutley, NJ
⁵Hackensack Meridian Health, Hackensack
⁶Temple University School of Medicine, Philadelphia, PA
⁷Center for Translational Medicine, Temple University, Philadelphia
⁸University of Pennsylvania, Philadelphia

Eduard Schulz, MD, PhD^1,2*, Noa G. Holtzman, MD^1,2, Alen Ostojic, MD^1*, Filip Pirsl^1*, Seth M. Steinberg, PhD^3*, Lauren M. Curtis, MD^4*, Brian C. Shaffer, MD⁵, Theo Heller, MD^6*, Ashley Carpenter, RRN^1*, Frances T. Hakim, PhD^7*, Jeffrey S. Rubin, MD, PhD^8* and Steven Z. Pavletic^1,2

¹Immune Deficiency Cellular Therapy Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD
²Myeloid Malignancies Program, National Institutes of Health, Bethesda, MD
³Biostatistics and Data Management Section, National Cancer Institute, National Institutes of Health, Bethesda, MD
⁴Ascension Saint Agnes Cancer Institute, Baltimore, MD
⁵Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York
⁶Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD
⁷Experimental Transplantation and Immunotherapy Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD
⁸NA, Potomac, MD

Fei Gao, MD^1*, Hengwei Wu, MD^1*, Xin Jin, MD^1*, Jimin Shi^1,2,3*, Yi Luo^1,3,4,5, Yanmin Zhao, MD^6* and He Huang^1*

¹Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
²Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy, Hangzhou, China
³Zhejiang Laboratory for Systems & Precision Medicine, Zhejiang University, Hangzhou, China
⁴Institute of Hematology, Zhejiang University, Hangzhou, China
⁵Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy, Zhejiang University, Hangzhou, China
⁶Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, People's Republic of China, Hangzhou, China

Yoon Seok Choi, MD, PhD^1,2, Na Yeon Seong, BS^2,3*, Yuri Lee, MS^2,3*, Jun Soung Park, MD^3*, Cheongin Yang, MD^2,3*, Minsuk Kwon, MD, PhD^3*, Seong Hyun Jeong, MD^3* and Joon Seong Park, MD^3*

¹Department of Hematology-Oncology, Ajou University School of Medicine, Suwon, South Korea
²Laboratory of Human Immunology and Blood Disorders, Department of Biomedical Science, Ajou University Graduate School, Suwon, Korea, Republic of (South)
³Department of Hematology-Oncology, Ajou University School of Medicine, Suwon, Korea, Republic of (South)

Kevin Quann, MD, PhD¹, Kentin Codispot, BS^2*, Alexander M. Rowe, PhD^3*, Wenzhong Wei^3*, Daniel Wikenheiser, PhD^4*, Emily McFerran, BS^1*, Mark Shlomchik, MD, PhD^3* and Warren Shlomchik, MD^1*

¹Department of Medicine, Division of Hematology/Oncology, University of Pittsburgh, Pittsburgh, PA
²Department of Medicine, Division of Hematology/Oncology, University of Pittsburgh, Pittsburgh
³Department of Immunology, University of Pittsburgh, Pittsburgh, PA
⁴BlueSphere Bio, Pittsburgh, PA

Huanle Gong, PhD^1*, Yaoyao Shen, MD^1*, Xiaojin Wu, MD^2*, Fulian Lv, PhD^1*, Yang Xu^1* and Depei Wu³

¹The First Affiliated Hospital Of Soochow University, Suzhou, China
²The First Affiliated Hospital Of Soochow University, Suzhou, Jiangsu, CHN
³The First Affiliated Hospital of Soochow University, Suzhou, China

Qingxiao Song, MD, PhD^1*, Yuankun Zhang^2*, Kaniel Cassady, PhD^1,3, Qinjian Li^4*, Paul J. Martin, MD⁵ and Defu Zeng, MD²

¹Arthur D. Riggs Diabetes and Metabolism Research Institute, The Beckman Research Institute, City of Hope National Medical Center, Duarte, CA
²Department of Immunology and Theranostics, Arthur Riggs Institute of Diabetes and Metabolism Research, Beckman Research Institute of City of Hope, Duarte, CA
³Regeneron Pharmaceuticals, Tarrytown, NY
⁴Hematologic Malignancies and Stem Cell Transplantation Institute, City of Hope National Comprehensive Cancer Center, Duarte, CA
⁵Fred Hutchinson Cancer Center, Seattle, WA

Wenkai Zhang, MD^1*, Xie-Na Cao, MD, PhD^1*, Wei Shi, PhD^1*, Linghui Xia^1*, Li Li, MD, PhD², Chun-Yan Sun^3* and Yu Hu, MD^4*

¹Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
²Santa Clara Valley Healthcare, San Jose, CA
³Department of Hematology, Union Hospital, Tongji Medical Collage, Huazhong University of Science and Technology, Wuhan, China
⁴Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

Dana Yehudai-Ofir^1,2*, Nasren Eiza^3*, Israel J. Henig, MD^2*, Tsila Zuckerman, MD^1,2 and Zahava Vadasz^3*

¹The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel
²Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus, Haifa, Israel
³Proteomic and Clinical Flow Cytometry Unit, Bnai Zion Medical Center, Haifa, Israel

Jeong-A Kim¹, Jinhang Kim, MD^2*, Saetbyeol Kim^2* and Misuk Yang^2*

¹Department of Hematology, St. Vincent Hospital, The Catholic University of Korea, Suwon, South Korea
²Department of Hematology, St. Vincent Hospital, The Catholic University of Korea, Suwon, Korea, Republic of (South)

Patrick Mellors, MD¹, Ana Nottingham^2,3*, Maksim Shestov^4*, Maria Basil, MD, PhD^2,3* and Saar Gill, MD, PhD^4,5

¹Division of Hematology/Oncology, Department of Medicine, University of Pennsylvania, Rochester, MN
²Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
³Penn-CHOP Lung Biology Institute and Penn Cardiovascular Institute, Perelman School of Medicine, Philadelphia, PA
⁴Division of Hematology/Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, PA
⁵Center for Cellular Immunotherapies, University of Pennsylvania School of Medicine, Philadelphia, PA

Yuyan Shen^1*, Tingting Zhang^2*, Zhangjie Chen^3*, Sisi Zhen^4*, Jieru Wang^5*, Erlie Jiang, PhD⁴, Xudong Liao^6* and Sizhou Feng^7*

¹Institute of Hematology & Blood Diseases Hospital, Tianjin, China
²Institute of Hematology & Blood Disease Hospital,Chinese Academy of Medical Sciences, Tianjin, China
³Institute of Hematology and blood diseases hospital, Chinese Academy of Medical Sciences, Tianjin, China
⁴State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences &Peking Union Medical College, Tianjin, China
⁵Institute of Hematology, Chinese Academy of Medical Sciences, Tianjin, China
⁶State Key Laboratory of Medicinal Chemical Biology, Frontiers Science Center for Cell Responses, Tianjin Key Laboratory of Protein Science, College of Life Sciences, Nankai University, Tianjin, China
⁷National Key Laboratory of Blood Science, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences &Peking Union Medical College, Tianjin, China

Swathi Shrihari^1*, Elisabetta Foppiani^1*, Kyndal Goss^1*, Georgette Gafford^2*, Lisa Daley-Bauer^1* and Edwin Horwitz, MD, PhD²

¹Emory University, Atlanta, GA
²Emory University, Atlanta