Laura Girardi, MD^1,2*, Rebecca Auer, MD, MSc^3*, Ranjeeta Mallick, PhD, MSc^4*, Tzu-Fei Wang, MD, MPH⁵ and Marc Carrier, MD⁵

¹Department of Medicine and Surgery, University of Insubria, Ottawa, ON, Canada
²Department of Medicine, The Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada
³Department of Surgery, The Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada
⁴Ottawa Hospital Research Institute, Ottawa, Canada
⁵Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada

Joao Manoel Da Silveira Lara, MD^* and Claudia Dourado, MD

Einstein Medical Center, Philadelphia, PA

Jennifer Alami, PharmD^1*, Henry A Feldman, PhD^2*, Alison Hanson, PharmD, BCPPS^1*, Riten Kumar, MBBS³, Martha Sola-Visner, MD⁴ and Patricia Ellen Davenport, MD^4*

¹Department of Pharmacy, Boston Children's Hospital, Boston, MA
²Institutional Centers for Clinical and Translational Research, Boston Children's Hospital, Boston, MA
³Dana Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA
⁴Division of Newborn Medicine, Boston Children's Hospital, Boston, MA

Jean M. Connors, MD¹, Tamara A Sussman, MD^2*, Ian D Dryg, PhD^3*, Anita Giobbe-Hurder, MS^3*, Michael P Manos, BS^4*, Jason L. Weirather, PhD^5* and Stephen Hodi, MD^6*

¹Hematology Division, Brigham and Women's Hospital, Boston, MA
²Dana Farber cancer Institute, Boston, MA
³Department of Data Sciences, Dana Farber Cancer Institute, Boston, MA
⁴Center for Melanoma Oncology, Dana Farber Cancer Institute, Boston, MA
⁵Department of Data Science, Dana-Farber Cancer Institute, Boston, MA
⁶Dana Farber Cancer Institute, Boston, MA

Steven Callori, MPH, BS^1*, Robert D. McBane, MD^2*, Danielle T. Vlazny, PA-C^2*, Damon E. Houghton, MD, MS^2,3, David Froehling, MD^4*, David O. Hodge^5*, Ana I. Casanegra, MD^2* and Waldemar E. Wysokinski, MD, PhD^2*

¹Mayo Clinic Alix School of Medicine, Rochester, MN
²Gonda Vascular Center, Mayo Clinic, Rochester, MN
³Department of Cardiovascular Diseases, Division of Vascular Medicine & Dept of Medicine, Division of Hematology, Mayo Clinic, Rochester, MN
⁴Mayo Clinic, Rochester, MN
⁵Mayo Clinic, Jacksonville, FL

Asaad Trabolsi, MD¹, Thomas Plate IV, MD¹, Rachel S. Kronenfeld, MD², Leticia E. Campoverde, MD³, Dan Morgenstern Kaplan, MD, MSc^4*, Alyssa Mercadel, MD^5*, Michael Caballero, PhD^6*, Wei Zhao^7*, Izidore S. Lossos, MD⁸, Craig H. Moskowitz, MD⁹ and Gerald A. Soff, MD¹⁰

¹Sylvester Comprehensive Cancer Center, University of Miami/ Jackson Memorial Hospital, Miami, FL
²Division of Pediatric Hematology/Oncology, University of Miami/Jackson Memorial Hospital, Miami, FL
³Internal Medicine Residency program, Department of Medicine, University of Miami/ Jackson Memorial Hospital, Miami, FL
⁴Internal Medicine Residency program, division of internal medicine, Department of Medicine, University of Miami/ Jackson Memorial Hospital, Miami
⁵Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Miami Leonard M. Miller School of Medicine, Miami
⁶Data Science and Engineering, UHealth Information Technology, University of Miami, Miami, FL
⁷Biostatistics and Bioinformatics Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL
⁸Sylvester Comprehensive Cancer Center, Division of Hematology, University of Miami School of Medicine, Miami, FL
⁹Sylvester Comprehensive Cancer Center, University of Miami, Coral Gables, FL
¹⁰Sylvester Comprehensive Cancer Center, University of Miami Miller School of medicine, Miami, FL

Evangelia Vlachodimtropoulou Koumoutsea, MBBS, PhD, BSc^1*, A. Kinga Malinowski, MD², Adam Cuker, MD, MS^3*, Eric Kaplovitch, MD^4* and Nadine Shehata, MD^5*

¹King's College Hospital, London, United Kingdom
²Department of Obstetrics and Gynaecology, Division of Maternal-Fetal Medicine, Lunenfeld-Tanenbaum Research Institute, Sinai Health, University of Toronto, Toronto, ON, CAN
³University of Pennsylvania, Philadelphia, PA
⁴Internal Medicine & Thrombosis, Mount Sinai Hospital, Toronto, ON, Canada
⁵Mount Sinai Hospital, Toronto, ON, Canada

Anuj Bharatkumar Patel, MD^1*, Vicky Mai, MD, MSc^1*, Lucia Caiano, MD^2*, Mathieu Mercier, MD^1*, Marc Carrier, MD³, Gregoire Le Gal, MD, PhD¹ and Lana Castellucci, MD, MSc¹

¹Department of Medicine, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada
²University of Insubria, Varese, Italy
³Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada

Janneke Spiegelenberg, MD^1,2*, Mark Roest^3*, Bas De Laat⁴, Marleen van Gelder, PhD^5*, Saskia Middeldorp, MD, PhD¹, Anil Tuladhar, MD, PhD^6,7*, Jenneke Leentjens, MD, PhD^1* and Frank-Erik De Leeuw, MD, PhD^6,7*

¹Internal medicine, Radboud University Medical Center, Nijmegen, Netherlands
²Synapse Research Institute, Maastricht, Netherlands
³Department of Platelet Pathophysiology, Synapse Research Institute, Maastricht, Netherlands
⁴Department of Functional Coagulation, Synapse Research Institute, Maastricht, Netherlands
⁵Department for Health Evidence, Radboud University Medical Center, Nijmegen, Netherlands
⁶Department of Neurology, Center for Neuroscience, Radboud University Medical Center, Nijmegen, Netherlands
⁷Donders Institute for Brain, Cognition and Behaviour, Nijmegen, Netherlands

Isabelle Mahe, MD, PhD^1*, Céline Chapelle^2*, Luis Jara-Palomares^3*, Olivier Sanchez^4*, Philippe Girard^5*, Guy Meyer^6*, Agnes Yuet Ying Lee, MD, MSc⁷, Géraldine Poénou^8* and Silvy Laporte, MS, PhD^9*

¹Internal Medicine department, Paris Cité University, Louis Mourier Hospital , APHP, Inserm UMR-S1140, Innovations Thérapeutiques en Hémostase, Paris, France; F-CRIN INNOVTE Network, France, COLOMBES, France
²Univ. Jean Monnet, Mines Saint-Etienne, INSERM, U1059, SAINBIOSE, CHU Saint-Etienne ; Service de pharmacologie clinique, F-42023, Saint-Etienne; F-CRIN INNOVTE Network, France, Saint-Etienne, France
³Medical Surgical Unit of Respiratory Diseases, Instituto de Biomedicina de Sevilla (IBiS), Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Hospital Universitario Virgen del Rocio, Seville, Spain, Séville, Spain
⁴Université Paris Cité, Service de Pneumologie et Soins Intensifs, Hôpital Européen Georges Pompidou, APHP, Paris, France; INSERM UMR_S1140, Innovations Thérapeutiques en Hémostase, Laboratoire de Chirurgie expérimentale, Fondation Alain Carpentier, Paris;, Paris, France
⁵Département de Pneumologie, Institut Mutualiste Montsouris, Paris; F-CRIN INNOVTE Network, France., Paris, France
⁶Université Paris Descartes, Paris, FRA
⁷BC Cancer Center, Vancouver, BC, CAN
⁸Univ. Jean Monnet, Mines Saint- Etienne, INSERM, U1059, SAINBIOSE, CHU Saint-Etienne; Service de Médecine Vasculaire et Thérapeutique, CHU Saint-Etienne, Hôpital Nord, Saint-Etienne, France. F-CRIN INNOVTE Network, France, Saint-Etienne, France
⁹Univ. Jean Monnet, Mines Saint-Etienne, INSERM, U1059, SAINBIOSE, CHU Saint-Etienne ; Service de pharmacologie clinique, F-42023, Saint-Etienne; F-CRIN INNOVTE Network, France., SAINT-ETIENNE, FRA

Amy L Kiskaddon^1*, Marisol Betensky, MD², Nhue Do, MD, MBA^3*, Arabela Stock, MD^2*, James Quintessenza, MD^2* and Neil Goldenberg, MD, PhD²

¹Johns Hopkins All Children's Hospital, Tarpon Springs, FL
²Johns Hopkins All Children's Hospital, Saint Petersburg, FL
³Vanderbilt University Medical Center, Nashville, TN

Joshua S Brunton, DO^1*, Danielle T. Vlazny, PA-C^2*, Damon E. Houghton, MD, MS³, Waldemar E. Wysokinski, MD, PhD^2*, Carl H Rose, MD^4* and Ana I. Casanegra, MD^2*

¹Division of Obstetrics, Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN
²Gonda Vascular Center, Mayo Clinic, Rochester, MN
³Department of Cardiovascular Diseases, Division of Vascular Medicine & Dept of Medicine, Division of Hematology, Mayo Clinic, Rochester, MN
⁴Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN

Thomas Plate IV, MD¹, Asaad Trabolsi, MD¹, Rachel S. Kronenfeld, MD², Leticia E. Campoverde, MD³, Dan Morgenstern Kaplan, MD, MSc^4*, Alyssa Mercadel, MD^5*, Michael Caballero, PhD^6*, Wei Zhao, MD, MS^7* and Gerald A. Soff, MD⁸

¹Sylvester Comprehensive Cancer Center, University of Miami/ Jackson Memorial Hospital, Miami, FL
²Division of Pediatric Hematology/Oncology, University of Miami/Jackson Memorial Hospital, Miami, FL
³Internal Medicine Residency program, Department of Medicine, University of Miami/ Jackson Memorial Hospital, Miami, FL
⁴Internal Medicine Residency program, division of internal medicine, Department of Medicine, University of Miami/ Jackson Memorial Hospital, Miami
⁵Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Miami Leonard M. Miller School of Medicine, Miami
⁶Data Science and Engineering, UHealth Information Technology, University of Miami, Miami, FL
⁷Sylvester Comprehensive Cancer Center, Department of Public Health Sciences, Miami
⁸Sylvester Comprehensive Cancer Center, University of Miami Miller School of medicine, Miami, FL

Rushad Machhi, MD^1*, Wafik Sedhom, MD^2*, Rachel Kasimer, MD^3* and Karlyn A. Martin, MD, MS⁴

¹McGaw Medical Center of Northwestern University, Department of Medicine, Chicago, IL
²Division of Hematology/Oncology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL
³Division of Hospital Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL
⁴University of Vermont Larner College of Medicine, Burlington, VT

Ce Cheng, DO¹, Anqi Lang, MS^2*, Stephanie J Hoffman, MD, BS³ and Jerome D Winegarden, MD³

¹Trinity Health Ann Arbor, Canton, MI
²Banner Health, Phoenix, AZ
³Trinity Health Ann Arbor, Ypsilanti, MI

Tzu-Fei Wang, MD, MPH^1,2, Roger Kou, BHSc^3*, Marc Carrier, MD^1,2 and Aurélien Delluc, MD, PhD^1,2*

¹Department of Medicine, The Ottawa Hospital and the University of Ottawa, Ottawa, ON, Canada
²Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada
³Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada

Laura Girardi, MD^1,2*, Leonardo Ciuffini, MD^3*, Vicky Mai, MD, MSc^4*, Marc Carrier, MD⁵ and Gregoire Le Gal, MD, PhD⁴

¹Department of Medicine and Surgery, University of Insubria, Ottawa, ON, Canada
²Department of Medicine, The Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada
³Thrombosis and Haemorragic Diseases Unit, IRCCS Humanitas Research Hospital, Milan, Italy
⁴Department of Medicine, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada
⁵Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada

Zeina Kayali, MBBS¹, Gustavo Garcia, MD^1*, Karen Hamad, MD, FAAP, FACP^2*, Wilhelmine Wiese-Rometsch, MD, FACP^2* and Ke Ning, MD^3*

¹Florida State University / Sarasota Memorial Hospital, Sarasota, FL
²Sarasota Memorial Hospital, Sarasota, FL
³Florida Cancer Specialists, Sarasota, FL

Cameron Brown^1*, Sarah Ng, MD^2,3*, Farah Zarka, MD^4*, Aurélien Delluc, MD, PhD^5,6* and Marc Carrier, MD^5,6

¹Department of Medicine, Ottawa Hospital Research Institute, Ottawa, ON, Canada
²University Of South Wales, Sydney, Australia
³Department of Haematology, Liverpool Hospital, Sydney, Australia
⁴Department of Medicine, Ottawa Hosptial Research Institute, Ottawa, ON, Canada
⁵Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada
⁶Department of Medicine, The Ottawa Hospital and the University of Ottawa, Ottawa, ON, Canada

Tony Owusu^1*, Andriy Derkach, PhD^2*, Miranda Burge^3*, David Nemirovsky, MS^2* and Jeffrey I. Zwicker, MD^3,4,5

¹Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, New York, NY
²Department of Biostatistics and Epidemiology, Memorial Sloan Kettering Cancer Center, New York, NY
³Memorial Sloan Kettering Cancer Center, New York, NY
⁴Beth Israel Deaconess Medical Center Harvard Medical School, Boston, MA
⁵Department of Medicine, Weill Cornell Medical College, New York, NY

Evgeny Grishin^1*, Michalle Soudack^2*, Aaron Lubetsky, MD, MSc³, Sarina Levy-Mendelovich, MD⁴, Omri Cohen^5*, Amos Toren, MD, PhD^6*, Bella Bielorai, MD^7*, Gili Kenet, MD^8* and Assaf Arie Barg^5*

¹Tel Aviv University, Tel Aviv, Israel
²Sheba Medical center, Tel-Aviv University, Tel Aviv, Israel
³National Hemophilia Center, Sheba Medical Center, Tel Hashomer, Israel; Amalia Biron Research Institute of Thrombosis and Hemostasis, Tel Aviv University, Israel., Tel Hashomer, ISR
⁴Tel Aviv University, Kiryat Ono, ISR
⁵National Hemophilia Center, Sheba Medical Center, Tel Hashomer, Israel; Amalia Biron Research Institute of Thrombosis and Hemostasis, Tel Aviv University, Israel., Tel Aviv, Israel
⁶Sheba Medical Center, Ramat Gan, Israel
⁷Tel Aviv University, Ramat-Gan, AL, ISR
⁸National Hemophilia Center, Sheba Medical Center, Tel Hashomer, Israel; Amalia Biron Research Institute of Thrombosis and Hemostasis, Tel Aviv University, Tel Aviv, Israel

Maria J. Fernandez Turizo¹, Shriram K. Sundararaman, MD^1*, Laura Dodge, ScD^2*, Eric J. Miller, MD^1*, Erik J. Uhlmann, MD^3*, Deepa Rangachari, MD^4*, Jeffrey I. Zwicker, MD⁵ and Rushad Patell, MBBS⁶

¹Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
²Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA
³Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
⁴Division of Medical Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
⁵Beth Israel Deaconess Medical Center Harvard Medical School, Boston, MA
⁶Division of Medical Oncology and Hematology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA