Min Zhu^*, Daniela Conrado^*, Kamal Srinivasan^*, Jurriaan Brouwer-Visser^*, Hong Yan^*, Hesham Mohamed, Aafia Chaudhry, Srikanth Ambati^*, Lutz Harnisch^* and John D Davis^*

Regeneron Pharmaceuticals, Inc., Tarrytown, NY

Dipti Talaulikar, PhD, FRACP, FRCPA, MBBS¹, Abhimanu Pandey, PhD^2*, Shweta Venkataraman^3*, Dhanvi Vedantham^2* and Si Ming Man^2*

¹Australian National University, Canberra, ACT, Australia
²Division of Immunology and Infectious Disease, John Curtin School of Medical Research, Australian National University, Canberra, Australia
³Division of Immunology and Infectious Disease, John Curtin School of Medical Research, Australian National University, Canberra, ACT, Australia

Jutta Deckert, PhD¹, Jenny Thirlway, PhD^1*, Justyna Mysliwy, PhD^2*, Adam Lodge, PhD^2* and Robert J Lutz, PhD^2*

¹Iksuda Therapeutics Ltd, Newcastle-upon-Tyne, United Kingdom
²Iksuda Therapeutics Ltd, Newcastle upon Tyne, United Kingdom

George Ward^1*, Zhiqiang Zhang, PhD^1*, Simone Jueliger, PhD^1*, Ilya Potapov, PhD^1*, Matthew P Davis, PhD^1*, Adam Boxall^1*, Jason A Taylor, MD, PhD², Harold N. Keer, MD, PhD², Andrea Biondo, MD, PhD^1*, John F Lyons, PhD^1*, Martin Sims, PhD^1* and Tomoko Smyth, PhD^1*

¹Astex Pharmaceuticals, Cambridge, United Kingdom
²Astex Pharmaceuticals, Inc., Pleasanton, CA

Kevin J. Hamblett^*, Julia Cochran^*, Katie Snead^*, Steven Jin^*, Roma Yumul^*, Jessica Simmons^*, Ivan Stone^*, Ryan Lyski^*, Jason P. Schrum^*, Andrea R. Lim^* and Astrid Clarke^*

Seagen, Inc., Bothell, WA

Masaya Abe, MD^1*, Noboru Asada, MD, PhD², Maiko Kimura^1*, Chie Fukui^3*, Daisuke Yamada^4*, Ziyi Wang^5*, Masayuki Miyake^6*, Takeshi Takarada^4*, Mitsuaki Ono^5*, Michinori Aoe^6*, Wataru Kitamura^1*, Masayuki Matsuda^1*, Takashi Moriyama^1*, Akifumi Matsumura^1* and Yoshinobu Maeda, MD, PhD¹

¹Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
²Department of Hematology and Oncology, Okayama University Hospital, Okayama, Japan
³Division of Hematology, Department of Medicine, Kobe University Hospital, Kobe, Japan
⁴Department of Regenerative Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
⁵Department of Molecular Biology and Biochemistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
⁶Division of Medical Support, Okayama University Hospital, Okayama, Japan

Ning Ding^1*, Yan Xie^2*, Yong Guo, MD^3*, Kecheng Li^3*, Tingting DU^2*, Zhenjun Li^2*, Yuejiao Li^2*, Jiaowu Cao^1*, Dingyao Hu^2*, Lih-Yun Hsu^4*, Richard Miller^4*, Jun Zhu, PhD⁵ and Yuqin Song, MD⁶

¹Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Lymphoma, Peking University Cancer Hospital & Institute (Beijing Cancer Hospital), Beijing, China
²Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Lymphoma, Peking University Cancer Hospital & Institute (Beijing Cancer Hospital), BEIJING, China
³Angel Pharmaceuticals Co., Ltd., Jiaxing, China
⁴Corvus Pharmaceuticals Inc, Burlingame
⁵Department of Lymphoma, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, Beijing, China
⁶Department of Lymphoma, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, BEIJING, China

Irfan Azaman, BSc^1*, Wee-Joo Chng, MBBS, PhD, FRCPath, FRCP^1,2,3,4,5, Nurulhuda Mustafa, PhD^1,6* and Sanjay De Mel, BSc, FRCPath, MRCP^3,7*

¹Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore
²National University Hospital National University Cancer Institute, Singapore, Singapore
³National University Hospital, Singapore, SGP
⁴Department of Haematology-Oncology, National University Cancer Institute, Singapore, Singapore
⁵Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
⁶Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
⁷Department of Haematology-Oncology, National University Cancer Institute, Singapore, Singapore, Singapore

Yoshihito Horisawa^1*, Kotaro Shirakawa, MD, PhD¹, Suguru Takeuchi, MD^1*, Ryosuke Nomura, MD^1*, Yusuke Tashiro^1*, Stanford Emani^1*, Jelagat Caroline^1*, Yasuhiro Kazuma, MD, PhD^1*, Kosuke Yusa, PhD^2* and Akifumi Takaori-Kondo, MD, PhD¹

¹Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
²Laboratory of Stem Cell Genetics, Institute for Life and Medical Sciences, Kyoto University, Kyoto, Japan

Tatsuya Terasaki, MD^1*, Yuichiro Semba, MD, PhD^2*, Kensuke Sasaki, MD, PhD^2*, Kiyoko Miyata, PhD^2*, Takuji Yamauchi, MD, PhD^2*, Hiroshi Imanaga, MD^2*, Fumihiko Nakao, MD^3*, Shigeki Hirabayashi, MD, PhD^2*, Jumpei Nogami, PhD^2*, Koshi Akahane, MD, PhD^4*, Takeshi Inukai, MD, PhD^4*, Koichi Akashi, MD, PhD^2* and Takahiro Maeda, MD, PhD²

¹Kyushu University Graduate School of Medical Sciences, Fukuoka, FKO, Japan
²Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
³National Hospital Organization Kyushu Medical Center, Fukuoka, Japan
⁴Department of Pediatrics, School of Medicine, University of Yamanashi, Chuo, Japan

Stefanie Enzenmüller, PhD^1*, Alexandra Niedermayer, MSc^1*, Felix Seyfried^1*, Alexander Groß, PhD^2*, Klaus-Michael Debatin, Prof. Dr.¹ and Lüder Hinrich Meyer, Prof. Dr.^1*

¹Department of Pediatrics and Adolescent Medicine, Ulm University Medical Center, Ulm, Germany
²Department of Medical Systems Biology, Ulm University Medical Center Ulm, Ulm, Germany

Faryal Munir, MD, MBBS^1,2, Shayaun Khazaei, BS^1*, Phoebe H. Calkins^1*, Darah Scruggs, MS^1*, Hideaki Mizuno, MD, PhD^1*, Lauren B. Ostermann, BSc^1*, Branko Cuglievan³, Miriam B. Garcia, DO^2*, Dong Chen, PhD^4*, Youzhi Tong, PhD^4*, Zhihua Ren, PhD^4*, Michael Andreeff, MD PhD⁵ and Yuki Nishida, MD, PhD¹

¹Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, TX
³The University of Texas MD Anderson Cancer Center, Houston, TX
⁴Kintor Pharmaceutical Ltd, Suzhou, China
⁵Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX

Victoria da Silva-Diz, PhD¹, Maya Aleksandrova^2*, Amartya Singh^2*, Eric Chiles^2*, Xiaoyang Su^2* and Daniel Herranz, PharmD, PhD³

¹Rutgers University, Highland Park, NJ
²Rutgers University, New Brunswick, NJ
³Cancer Institute of New Jersey-Rutgers University, New Brunswick, NJ

Anna Pia Enblad^1,2*, Olga Krali^2*, Kristin Blom^2*, Claes Andersson^2*, Britt-Marie Frost^1*, Josefine Palle^1*, Arja Harila^1*, Erik Forestier^3,4*, Jukka Kanerva^4,5*, Trond Flægstad^4,6*, Ólafur G Jónsson^4,7*, Kjeld Schmiegelow, MD^4,8,9, Mats Heyman^4,10,11, Peter Nygren^12*, Rolf Larsson^2*, Gudmar Lönnerholm^1* and Jessica Nordlund^2*

¹Department of Women’s and Children’s Health, Uppsala University, Uppsala, Sweden
²Department of Medical Sciences and Science for Life Laboratory, Uppsala University, Uppsala, Sweden
³Department of Medical Biosciences, Umeå University, Umeå, Sweden
⁴For the Nordic Society of Pediatric Hematology and Oncology (NOPHO), Stockholm, Sweden
⁵Division of Hematology, Oncology and Stem Cell Transplantation, Helsinki University Central Hospital, Helsinki, Finland
⁶Department of Pediatrics, Tromsø University and University Hospital, Tromsø, Norway
⁷Pediatric Hematology-Oncology, Children’s Hospital, Barnaspitali Hringsins, Landspitali University Hospital, Reykjavík, Iceland
⁸Medical Faculty, Institute of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
⁹Department of Pediatrics and Adolescent Medicine, Rigshospitalet, Copenhagen, Denmark
¹⁰Childhood Cancer Research Unit, Karolinska Institute, Stockholm, Sweden
¹¹Astrid Lindgren Children’s Hospital, Karolinska University Hospital, Stockholm, Sweden
¹²Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden

Kimberly Johansson, BA^1,2, Iryna V Dmytrenko, PhD^2*, Megan Gauthier, MD^2*, Feng Gao, MD, PhD^2* and Daniel C. Link, MD²

¹Medical Scientist Training Program, Washington University in St. Louis, St. Louis, MO
²Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO

Jay Kang, MS^1*, Jason Ostergaard, BS^1* and Peter Gordon, MD/PhD²

¹Pediatric Hematology/Oncology, University of Minnesota, Minneapolis, MN
²Masonic Cancer Center, University of Minnesota, Minneapolis, MN

Xiaoyun Wu^1*, Shariful Islam, PhD^1*, Derek B Oien, PhD^1*, Collin Tokheim, PhD^1*, Alex Beacom^1*, Neeraj Aryal, PhD^1*, Michelle Hsueh^2*, Muskan Floren, PhD², Douglas Ross-Thriepland, PhD^3*, Daniel Barrell^3*, Ultan McDermott, PhD^3*, Veerendra Munugalavadla, PhD², Daniel Auclair, PhD¹, Simon Rule, MD^4*, Arthur Shaffer^5*, Jude Fitzgibbon, PhD^1* and Lisa Drew, PhD^1*

¹AstraZeneca, Waltham, MA
²AstraZeneca, South San Francisco, CA
³AstraZeneca, Cambridge, United Kingdom
⁴AstraZeneca, Mississauga, ON, Canada
⁵AstraZeneca, Gaithersburg, MD

Shady I. Tantawy, MD¹, Natalia Timofeeva, MD¹, Hitomi Fujiwara, PhD^2*, Mariko Hatakeyama^2*, Breana Herrera^1*, Lizbeth Loza^1*, Tokiko Asami^2*, Hiroshi Ohmoto^2*, Kyoko Miyamoto^3*, Yu Nishioka^2*, Akinori Arimura, PhD^3*, Masaaki Sawa, PhD^2*, Nitin Jain, MD⁴ and Varsha Gandhi, PhD^1,4

¹Department of Experimental Therapeutics, MD Anderson Cancer Center, Houston, TX
²Carna Biosciences, Inc., Kobe, Japan
³CarnaBio USA, Inc., South San Francisco, CA
⁴Department of Leukemia, MD Anderson Cancer Center, Houston, TX

Ismini Halmer, MD^1,2,3*, Laura Beckmann, MD^1,2,3*, Gero Knittel, PhD^1,3,4*, Hamid Kashkar, PhD^5*, Hans Christian Reinhardt, MD^1,3,6, Michael Hallek, MD^1,2,3*, Alexandra Da Palma Guerreiro, PhD^1,2,3* and Lukas Peter Frenzel, MD^1,2,3*

¹Faculty of Medicine and Cologne University Hospital, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, University of Cologne, Cologne, Germany, Cologne, Germany
²CECAD, Center of Excellence on Cellular Stress Responses in Aging-Associated Diseases, Center for Molecular Medicine Cologne, Cologne, Germany, Cologne, Germany
³Center of Integrated Oncology Aachen Bonn Cologne Duesseldorf (ABCD), University Hospital Cologne, Cologne, Germany, Cologne, Germany
⁴Department of Hematology and Stem Cell Transplantation, University Hospital Essen, Essen, NRW, Germany
⁵Med. Microbiol. and Immunol. University of Cologne, Cologne, Germany
⁶Department of Hematology and Stem Cell Transplantation, University Hospital Essen, Essen, Germany

Yeong Jer Lim^1,2*, Andrew Duckworth^3*, Kim Clarke^4*, Melanie Oates^3*, Matthew Gornall^5*, Nagesh Kalakonda^1,3*, Joseph Slupsky^3* and Andrew Pettitt, MD, PhD^1,3*

¹The Clatterbridge Cancer Centre NHS Foundation Trust, Liverpool, United Kingdom
²Department of Molecular & Clinical Cancer Medicine, University of Liverpool, Warrington, ENG, United Kingdom
³Department of Molecular & Clinical Cancer Medicine, University of Liverpool, Liverpool, United Kingdom
⁴Computational Biology Facility, University of Liverpool, Liverpool, United Kingdom
⁵Liverpool Clinical Trials Centre, University of Liverpool, Liverpool, United Kingdom