-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

801.O2.6 801. Gene Therapies: New Approaches From Bench to Bedside Clinically Relevant Abstract

Symposia: Gene Therapies Program: Oral and Poster Abstracts
Type: Oral
Sunday, December 10, 2023: 9:30 AM-11:00 AM
Ballroom 20CD (San Diego Convention Center)
Moderators:
Allison P Wheeler, MD, The Vanderbilt University and Angela C Weyand, MD,
Disclosures:
No relevant conflicts of interest to declare.
9:30 AM

Gurbind Singh, PhD1*, Mohanashankar A M, MSc2*, Shaji R Velayudhan, PhD3,4*, Gabriela Denning, PhD5*, Abraham Sunder Singh, RN4*, Anbu Jeba, RN6*, Aby Abraham, MD, DM6*, Christopher B Doering, PhD7, H Trent Spencer, PhD8* and Alok Srivastava, MD, FRACP, FRCPA, FRCP9,10

1Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Vellore, India
2Centre for Stem Cell Research (a unit of inStem, Bengaluru), Vellore, India
3Centre for Stem Cell Research (a unit of inStem, Bengaluru), Vellore, Tamil Nadu, India
4Christian Medical College, Vellore (Ranipet Campus), Vellore, India
5Expression Therapeutics, Inc., Tucker, GA
6Christian Medical College Vellore (Ranipet Campus), Vellore, India
7Department of Pediatrics, Aflac Cancer and Blood Disorders Center, Emory University and Children's Healthcare of Atlanta, Atlanta, GA
8Emory University School of Medicine and Children’s Healthcare of Atlanta, Atlanta, GA
9Department of Haematology, Christian Medical College, Vellore, India
10Unit of inStem Bengaluru, Centre for Stem Cell Research, Vellore, India

9:45 AM

Vincent Muczynski, PhD1*, Eric Bun, MSc2*, Lewis Tanner, PhD1*, Jenny H. McIntosh, PhD1*, Olivier D. Christophe, PhD2* and Amit C. Nathwani, MD, PhD3,4

1Cancer Institute, University College London, London, United Kingdom
2UMR-S U1176 - HITh, INSERM, Le Kremlin Bicetre, France
3Royal Free London - NHS Foundation Trust, London, United Kingdom
4Cancer Institute, UCL, London, ENG, United Kingdom

10:00 AM

John DiPersio1, Brenda W Cooper, MD2, Hyung C Suh, MD/PhD3, Divya Koura, MD4, Lea Bernard, MD5, Nirali N. Shah, M.D.6, Roland B. Walter, MD, PhD, MS7, Miguel-Angel Perales, MD8, Markus Mapara, MD9, Roni Tamari, MD8, Michael R. Loken, PhD10*, Kyle Breitschwerdt11*, Sritama Nath, PhD11*, Glen D Raffel, MD12 and Guenther Koehne, MD, PhD13

1Division of Oncology, Washington University School of Medicine, Saint Louis, MO
2University Hospitals Seidman Cancer Center, Cleveland, OH
3Stem Cell Transplantation and Cellular Therapy Program, John Theurer Cancer Center, Hackensack Meridian Health, Hackensack, NJ
4UCSD Moores Cancer Center, La Jolla, CA
5Maisonneuve-Rosemont Hospital, Montreal, QC, CAN
6Pediatric Oncology Branch, National Institutes of Health, Bethesda, MD
7Translational Science and Therapeutics Division, Fred Hutchinson Cancer Research Center, Seattle, WA
8Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
9Blood and Marrow Stem Cell Transplantation Program, Division of Hematology & Oncology, Columbia University Irving Medical Center, New York, NY
10Hematologics, Inc., Seattle, WA
11Vor Biopharma, Cambridge, MA
12Vor Biopharma, Waban, MA
13Baptist Health South Florida, Miami Cancer Institute, Miami, FL

10:15 AM

Stefan Radtke1, Emily Fields2*, Gregory A. Newby, PhD3*, Jonathan S Yen, PhD4, Mitchell Weiss, MD, PhD5, Olivier Humbert, PhD2*, Dnyanada Pande2*, Mark Enstrom, PhD2*, David Liu, PhD6* and Hans-Peter Kiem1

1Fred Hutchinson Cancer Center, Seattle, WA
2Fred Hutchinson Cancer Center, Seattle
3Broad Institute of Harvard and MIT, Harvard University, Cambridge, MA
4Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN
5St. Jude Children's Research Hospital, Memphis, TN
6Harvard University, Cambridge, MA

10:30 AM

Simon N Chu, MD, MS1,2*, Eric Soupene, PhD3*, Beeke Wienert, PhD4*, Han Yin, BS5*, Devesh Sharma, MBBS1,2*, Kun Jia, PhD1,2*, Shota Homma, BA, BS6*, Jessica P Hampton, BS7, Bruce Conklin, MD8*, Tippi C. MacKenzie, MD1,2*, Matthew Porteus, MD, PhD9 and Kyle Cromer, PhD, MPhil, BS1,2,10

1Eli & Edythe Broad Center for Regeneration Medicine, University of California, San Francisco, San Francisco, CA
2Department of Surgery, University of California, San Francisco, San Francisco, CA
3Children’s Hospital of Oakland Research Institute, Oakland, CA
4Department of Medicine, University of California, South San Francisco, CA
5School of Medicine, University of California, San Francisco, San Francisco, CA
6Department of Genetics, Stanford University, Palo Alto, CA
7Stanford University, Stanford, CA
8Department of Medicine, University of California, San Francisco, San Francisco, CA
9Department of Pediatrics, Stanford University, Stanford, CA
10Department of Bioengineering & Therapeutic Sciences, University of California, San Francisco, San Francisco, CA

10:45 AM

Naoya Uchida, MD, PhD1,2, Selami Demirci, PhD3*, Anh Le3*, Rebecca Chu3*, Xiong Liu, PhD3*, Ling Su4*, Xiaolin Wu, PhD4*, Allen Krouse5*, N Seth Linde5*, Aylin Bonifacino5*, So Gun Hong, DVM, PhD6, Cynthia E. Dunbar, MD5, Leanne Lanieri7*, Anjali Bhat7*, Rahul Palchaudhuri, PhD7*, Bindu Bennet7*, Megan D. Hoban, PhD7*, Kirk Bertelsen, PhD7*, Lisa Olson, PhD7*, Robert Donahue, DVM3* and John F. Tisdale, MD3

1Cellular and Molecular Therapeutics Branch, NHLBI/NIDDK, NIH, NHLBI, MCHB, Bethesda, MD
2Division of Molecular and Medical Genetics, Center for Gene and Cell Therapy, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan
3Cellular and Molecular Therapeutics Branch, NHLBI/NIDDK, NIH, Bethesda, MD
4Genomics Technology Laboratory, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD
5Translational Stem Cell Biology Branch, NHLBI, NIH, Bethesda, MD
6Translational Stem Cell Biology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
7Magenta Therapeutics, Cambridge, MA

*signifies non-member of ASH