Mazyar Shadman, MD, MPH^1,2, Kwang Wooahn, PhD^3*, Manmeet Kaur^4*, Mohamed A. Kharfan-Dabaja, MD, MBA⁵, Alex F. Herrera, MD⁶, Craig S Sauter, MD⁷ and Mehdi Hamadani, MD⁸

¹Division of Medical Oncology, University of Washington, Seattle, WA
²Fred Hutchinson Cancer Center, Seattle, WA
³Medical College of Wisconsin, Cibmtr-Milwaukee, Milwaukee, WI
⁴Medical College of Wisconsin, Milwaukee, WI
⁵Department of Hematology/Oncology, Mayo Clinic, Jacksonville, FL
⁶City of Hope, Duarte, CA
⁷Department of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
⁸Division of Hematology and Oncology, The Medical College of Wisconsin Inc, Milwaukee, WI

Marc-Andrea Baertsch, MD^1,2*, Jana Schlenzka, MD^3*, Thomas Hielscher^4*, Marc S. Raab^2,5,6*, Sandra Sauer, MD^7*, Maximilian Merz, MD⁸, Elias K. Mai, M.D.^9*, Carsten Müller-Tidow, MD^5,10*, Steffen Luntz, MD^11*, Anna Jauch, PhD^12*, Peter Brossart, MD¹³, Martin Goerner, MD^14*, Stefan Klein, MD¹⁵, Bertram Glass, MD^16*, Peter Reimer, MD^17*, Ullrich Graeven, MD^18*, Roland Fenk, MD, PhD^19*, Mathias Hänel, MD²⁰, Ivana von Metzler, MD^21*, Lindemann Hans W., MD^22*, Christof Scheid, MD^23*, Axel Nogai, MD^24*, Hans Salwender, MD^25*, Richard Noppeney^26*, Britta Besemer, MD^27*, Katja Weisel, MD²⁸ and Hartmut Goldschmidt^5,29

¹Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany
²Department of Hematology, Oncology and Rheumatology, University Hospital Heidelberg, Heidelberg, Germany
³Department of Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany
⁴German Cancer Research Center, Heidelberg, DEU
⁵National Center for Tumor Diseases (NCT), Heidelberg University Hospital, Heidelberg, Germany
⁶Clinical Cooperation Unit (CCU) Molecular Hematology/Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany
⁷Department of Hematology, Oncology and Rheumatology, University Hospital Heidelberg, Heidelberg, DEU
⁸Department of Hematology, Cellular Therapy, Hemostaseology and Infectious Diseases, University Leipzig Medical Center, Leipzig, Germany
⁹Heidelberg Myeloma Center, Department of Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany
¹⁰Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany
¹¹Coordination Center for Clinical Trials (KKS), University Hospital Heidelberg, Heidelberg, Germany
¹²Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany, Heidelberg, DEU
¹³Department of Oncology, Hematology, Immuno-Oncology and Rheumatology, Med. Klinik und Poliklinik III, University Hospital Bonn, Bonn, Germany
¹⁴Department of Hematology, Oncology and Palliative Care, Community Hospital Bielefeld, Heidelberg, Germany
¹⁵Department of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, Mannheim, Germany
¹⁶Department of Hematology, HELIOS Klinikum Berlin-Buch, Berlin, Germany
¹⁷Evang. Kliniken Essen-Mitte, Evang. Krankenhaus Essen-Werden, Essen, Germany, Essen, Germany
¹⁸Department of Hematology, Oncology and Gastroenterology, Medical Clinic I, Hospital Maria Hilf GmbH, Mönchengladbach, Germany, Mönchengladbach, DEU
¹⁹Department of Hematology, Oncology and Clinical Immunology,, University Hospital Düsseldorf, Duesseldorf, Germany
²⁰Department of Internal Medicine III, Hematology, Oncology and Cellular Therapies, Hospital Chemnitz, Chemnitz, Germany
²¹Department of Internal Medicine II, University Hospital Frankfurt a.M., Frankfurt a.M., Germany, Frankfurt am Main, Germany
²²Department of Hematology and Oncology, Kath. Krankenhaus Hagen gem. GmbH, Hagen, Germany
²³Department of Internal Medicine I, University Hospital Cologne, Cologne, Germany, Cologne, Germany
²⁴Department of Hematology, Oncology and Cancer Immunology, Campus Benjamin Franklin, Charité-Universitätsmedizin Berlin, Berlin, Germany
²⁵Asklepios Tumorzentrum Hamburg, AK Altona and AK St. Georg, Hamburg, Germany
²⁶Department of Hematology, University Hospital Essen, Essen, Germany
²⁷University Hospital of Tuebingen, Tuebingen, Germany
²⁸Department of Oncology, Hematology and Bone Marrow Transplantation with Section of Pneumology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
²⁹Internal Medicine V, GMMG-Study Group, University Hospital Heidelberg, Heidelberg, Germany

Gordon Cook, PhD^1,2,3*, A J Ashcroft^4*, Ethan R Senior, MMath^2*, Catherine Olivier^2*, Anna Hockaday^5*, Jeanine Richards^2*, James D. Cavenagh, MD⁶, John Snowden, MD^7*, Mark Drayson^8*, Ruth M de Tute, MSc, PhD, FRCPath^9*, Roger Owen, MD, MRCP, FRCPath^10*, Kwee Yong¹¹, Mamta Garg, MD, MBBS, FRCP, FRCPath^12*, Kevin Boyd^13*, Hamdi Sati^14*, Sharon Gillson, BSc^15*, Mark Cook, MBChB, PhD¹⁶, David Allan Cairns, PhD^17* and Christopher Parrish, MBBChir, MRCP, FRCPath, MA, PhD^2,18

¹Leeds Cancer Centre, Leeds Teaching Hospital NHS Trust, Leeds, United Kingdom
²Leeds Institute of Clinical Trials Research, Cancer Research UK Clinical Trials Unit, Leeds, United Kingdom
³Leeds Myeloma Research Group and NIHR Leeds Biomedical Research Centre, Leeds, United Kingdom
⁴Mid-Yorks NHS Trust, Wakefield, GBR
⁵Leeds Cancer Research UK Clinical Trials Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, United Kingdom
⁶Department of Haematology, St. Bartholomew's Hospital, London, GBR
⁷Department of Haematology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom
⁸University of Birmingham, Institute of Immunology and Immunotherapy, Birmingham, United Kingdom
⁹HMDS, Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
¹⁰Leeds Teaching Hospitals NHS Trust, Haematological Malignancies Diagnostics Service, Leeds, United Kingdom
¹¹Department of Haematology, University College London, London, United Kingdom
¹²Leicester Royal Infirmary, Leicester, United Kingdom
¹³The Royal Marsden NHS Foundation Trust, London, United Kingdom
¹⁴Department of Haematology, Singleton Hospital, Swansea, GBR
¹⁵Leeds Institute of Clinical Trials Research, Cancer Research UK Clinical Trials Unit, Leeds, GBR
¹⁶Bristol Myers Squibb, Boudry, Switzerland
¹⁷Leeds Institute of Clinical Trials Research, Cancer Research UK Clinical Trials Unit, Leeds, ENG, United Kingdom
¹⁸Leeds Teaching Hospitals NHS Trust, Leeds Cancer Centre, Leeds, United Kingdom

June-Wha Rhee^1*, Raju Pillai, MD^2*, Sitong Chen, MPH^1*, Alysia Bosworth^1*, Liezl Atencio^1*, Artem Oganesyan^1*, Kendall Freeman^1*, Tati Guzman^1*, Kara Lukas^1*, Kelly Peng^1*, Brianna Sigala^1*, Aleksi Iujuridze^1*, Lanie Lindenfeld^1*, Faizi Jamal^3*, Alex F. Herrera, MD⁴, Matthew G. Mei, MD¹, Ryotaro Nakamura, MD⁵, F. Lennie Wong, PhD¹, Stephen J. Forman, MD, FACP⁶ and Saro Armenian, DO, MPH¹

¹City of Hope National Medical Center, Duarte, CA
²Department of Pathology, City of Hope National Comprehensive Cancer Center, Duarte, CA
³Division of Cardiology, Department of Medicine, City of Hope National Medical Center, Duarte, CA
⁴City of Hope, Duarte, CA
⁵Hematologic Malignancies and Stem Cell Transplantation Institute, City of Hope National Comprehensive Cancer Center, Duarte, CA
⁶Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope National Medical Center, Duarte, CA

Shohei Mizuno, MD, PhD^1*, Luuk Gras Sr., MD, PhD^2*, Laurien Baaij^3*, Linda Koster^3*, Anita D'Souza, MD, MS⁴, Parameswaran N. Hari, MD, MBBS⁵, Noel Estrada-Merly, MS^6*, Wael Saber, MD, MS⁷, Andrew J. Cowan, MD⁸, Minako Iida, MD, PhD^9*, Shinichiro Okamoto^10*, Hiroyuki Takamatsu, MD, PhD¹¹, Koji Kawamura, MD, PhD/Professor^12*, Yoshihisa Kodera, MD^13*, Nada Hamad, BSc MSc MBBS FRACP FRCPA¹⁴, Bor-Sheng Ko, M.D. Ph.D.^15*, Christopher Liam, MRCP^16*, KIM Wah HO, MBBS, MRCP^17*, Ai Sim Goh^18*, S. Keat Tan^19*, Alaa M. Elhaddad, MD²⁰, Ali Bazarbachi, MD, PhD²¹, Brig Qamar Un N Chaudhry, MBBS, FCPS^22*, Rozan Alfar^23*, Mohamed Amine Bekadja^24*, Malek Benakli, MD^25*, Cristobal Augusto Frutos, MD^26*, Eloisa Riva^27*, Sebastian Galeano, MD^28*, Francisca Bass, MD^29*, Hira Mian, MD³⁰, Arleigh McCurdy, MD, BSc³¹, Feng Rong Wang^32*, Daniel Neumann^33*, Mickey Boon Chai Koh, MD, PhD^34*, John Snowden, MD^35*, Stefan Schönland, MD^36*, Donal P McLornan, MD, PhD^37*, Patrick J Hayden, MD, PhD^38*, Anna Maria Sureda Balari, MD, PhD³⁹, Hildegard T. Greinix, MD⁴⁰, Mahmoud Aljurf, MD^41*, Yoshiko Atsuta, MD, PhD^42*, Dietger W. Niederwieser, MD⁴³ and Laurent Garderet, MD, PhD^44*

¹Aichi Medical University, Nagakute, AIC, Japan
²EBMT Statistical Unit, Leiden, Netherlands
³EBMT Leiden Study Unit, Leiden, Netherlands
⁴Medical College of Wisconsin, Milwaukee, WI
⁵Department of Medicine, Medical College of Wisconsin, Milwaukee
⁶BMT and Cellular Therapy Program, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI
⁷CIBMTR® (Center for International Blood and Marrow Transplant Research), National Marrow Donor Program/Be The Match, Minneapolis, MN
⁸Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA
⁹Aichi Medical University School of Medicine, Nagakute-cho, Aichi, JPN
¹⁰Keio University School of Medicine, Tokyo, JPN
¹¹Kanazawa University, Kanazawa, ISH, Japan
¹²Hematology, Tottori University Hospital, Yonago, Japan
¹³Aichi Medical University, Nagakute, AIC, JPN
¹⁴Haematology Department, The Kinghorn Cancer Centre, St Vincent's Hospital, Darlinghurst, NSW, Australia
¹⁵National Taiwan University Hospital, Taipei, Taiwan
¹⁶Hospital Sultanah Aminah, Johor Bahru, Malaysia
¹⁷Hospital Ampang, Ampang, Malaysia
¹⁸Hospital Pulau Pinang, Pinang, Malaysia
¹⁹Hospital Pulau Pinang, Pulau Pinang, Malaysia
²⁰Cairo University, Cairo, EGY
²¹American University of Beirut Dept. of Medicine, Beirut, Lebanon
²²Armed Forces Institute of Transplantation, Rawalpindi, PAK
²³King Hussein Cancer Center, Amman, Jordan
²⁴Établissement Hospitalier Universitaire 1 et Novembre, Ahmed Benbella 1 University, Oran, Algeria
²⁵Pierre and Marie Curie Center, Algiers, Algeria
²⁶Instituto de Prevision Social, Asuncion, Paraguay
²⁷Clinical Hospital Dr. Manuel Quintela De Clinicas, Montevideo, Uruguay
²⁸British Hospital, Montevideo, URY
²⁹Intensive Hematology Unit, Hospital Del Salvador, Santiago, Chile
³⁰McMaster University, Hamilton, ON, Canada
³¹The Ottawa Hospital, Ottawa, ON, Canada
³²Peking University, Peking, China
³³IMISE, university of Leipzig, Leipzig, Germany
³⁴St George's University Hospitals, London, United Kingdom
³⁵Department of Haematology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom
³⁶Universitätsklinikum Heidelberg, Heidelberg, Germany
³⁷University College London Hospitals NHS Trust, London, United Kingdom
³⁸Trinity College Dublin, St. James's Hospital, Dublin, IRL
³⁹Universitat de Barcelona, Barcelona, Spain
⁴⁰Medical University Graz, Graz, Austria
⁴¹King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
⁴²Japanese Data Center For Hematopoietic Cell Transplantation, Nagakute, Japan
⁴³University of Leipzig, Leipzig, Germany
⁴⁴Hôpital la pitié salpetriere, Paris, FRA

Leyre Bento^1*, Antonio Gutiérrez, MD, PhD^1*, Carmen Martínez^2*, Consejo Ortí^3*, Marina Sorribes^4*, Ana Carolina Caballero^4*, Marta Peña^5*, Ariadna Pérez^6*, Ana Jimenez Ubieto^7*, Mariana Bastos-Oreiro^8*, Paula Fernández Caldas-González^8*, Belén Navarro^9*, Isabel Salcedo^10*, Pau Abrisqueta Costa^11*, Ignacio Español^12*, Javier Cornago^13*, Fernando Martín-Moro^14*, Lucía García^15*, Pilar Gómez^16*, Rosario Varela^17*, María Puente^18*, Joud Zanabili^19*, Teresa Zudaire^20*, Izaskun Zeberio^21*, Raquel Del Campo^22*, Leslie González^23*, Pedro Gonzalez-Sierra^24*, Cristina Blázquez Goñi^25*, Jordina Rovira^26*, Marta Sitges^27*, Mireia Franch^28*, Almudena Cabero^29*, Alberto Mussetti^5*, Juan Montoro^3*, Antonia Sampol Mayol^1*, Anna Maria Sureda Balari, MD, PhD⁵, Dolores Caballero^29* and Alejandro Martín García-Sancho^29*

¹Hematology Department, Hospital Universitario Son Espases, IdISBa, Palma de Mallorca, Spain
²Hematology Department, Hospital Clinic, Barcelona, Spain
³Hematology Department, Hospital La Fe, Valencia, Spain
⁴Hematology Department, Hospital Santa Creu i Sant Pau, Barcelona, Spain
⁵Clinical Hematology Department, Institut Català d’Oncologia-Hospitalet, IDIBELL, Barcelona, Spain
⁶Hematology Department, Hospital Clínico de Valencia, Valencia, Spain
⁷Hospital Universitario 12 de Octubre, MADRID, MADRID, Spain
⁸Hematology Department, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain
⁹Hospital Universitario Puerta de Hierro, Majadahonda, Spain
¹⁰Hematology Department, Hospital Universitario Puerta de Hierro, Majadahonda, Spain
¹¹Vall d'Hebron University Hospital, Barcelona, Spain
¹²Hematology Department, Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain
¹³Hematology Department, Fundación Jiménez Díaz, Madrid, ESP
¹⁴Hematology Department, Hospital Ramón y Cajal, Madrid, Spain
¹⁵Hospital Morales Meseguer, Murcia, Spain
¹⁶Hematology Department, Hospital La Paz, Madrid, Spain
¹⁷Hematology Department, Complejo Hospitalario Universitario A Coruña, A Coruna, ESP
¹⁸Hematology Department, Hospital Universitario Marqués de Valdecilla, Santander, Spain
¹⁹Hematology Department, Hospital Universitario Central de Asturias, Oviedo, Spain
²⁰Hematology Department, Complejo Hospitalario de Navarra, Pamplona, ESP
²¹Hematology Department, Hospital Universitario Donostia, San Sebastian, ESP
²²Hematology Department, Hospital Universitario Son Llàtzer, Palma de Mallorca, ESP
²³Hematology Department, Hospital Universitario de Gran Canaria Dr. Negrín, Las Palmas de Gran Canaria, Spain
²⁴Hematology Department, Complejo Universitario de Granada, Granada, ESP
²⁵Hematology Department, Hospital Universitario Virgen del Rocío, Instituto de Biomedicina de Sevilla (IBIS / CSIC / CIBERONC), Sevilla, Spain
²⁶Hematology Department, Hospital Universitari de Tarragona Joan XXIII, Institut Català d`Oncologia, Tarragona, ESP
<sup>27</sup>Hematology Department, Institut Català d`Oncologia, Girona, ESP
²⁸ICO-IJC-Hospital Germans Trias i Pujol, Barcelona, Spain
²⁹Hematology Department, Hospital Universitario de Salamanca, IBSAL, CIBERONC, University of Salamanca, Salamanca, Spain