-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
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721.O4.6 721. Allogeneic Transplantation: Conditioning Regimens, Engraftment and Acute Toxicities: Novel Conditioning Regimens for Myeloid Malignancies

Symposia: Allogeneic Transplantation: Conditioning Regimens, Engraftment and Acute Toxicities Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Acute Myeloid Malignancies, AML, MDS, Biological therapies, MPN, Chronic Myeloid Malignancies, Diseases, Therapies, Myeloid Malignancies, Transplantation
Sunday, December 10, 2023: 9:30 AM-11:00 AM
Pacific Ballroom Salons 18-19 (Marriott Marquis San Diego Marina)
Moderators:
Boglarka Gyurkocza, MD, and Cristobal Augusto Frutos, MD, Instituto de Prevision Social and Meng Lv, MD, PhD, Peking University People's Hospital
Disclosures:
Gyurkocza: Actinium Pharmaceuticals, Inc: Research Funding.
This session presents novel approaches to conditioning regimens for patients with myeloid malignances undergoing allogeneic hematopoietic cell transplantation. Innovative regimens for patients with relapsed or refractory disease will be also discussed.
9:30 AM

Hannah Choe, MD1, Ben K. Tomlinson, MD2, Boglarka Gyurkocza, MD3, Rajneesh Nath4*, Stuart Seropian, MD5, Mark R. Litzow, MD6, Camille N. Abboud, MD7, Patrick J. Stiff, MD8, Sunil Abhyankar, MD9, James M. Foran, MD10, Sameem Abedin, MD11, George Chen, MD12,13, Zaid Al-Kadhimi, MD14,15*, Partow Kebriaei, MD16, Mitchell Sabloff, MSc, MD, FRCPC17, Johnnie J. Orozco, MD, PhD18, Katarzyna Joanna Jamieson, MD19*, Margarida Magalhaes-Silverman, MD20, Koen Van Besien, MD, PhD2,21, Michael W. Schuster, MD22, Arjun D. Law, MD23*, Sebastian A. Mayer, MD24, Hillard M. Lazarus, MD25, Jennifer Spross26*, Kate L Li, PhD26*, Elaina Haeuber, MS26*, Madhuri Vusirikala27*, Akash Nahar, MD, MPH26*, Brenda M. Sandmaier, MD28, John Pagel, MD, PhD29, Sergio A. Giralt, MD, FACP30, Avinash Desai, M.D26* and Nebu Koshy, MD31*

1Division of Hematology, Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH
2University Hospitals Seidman Cancer Center, Cleveland, OH
3Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
4Banner MD Anderson Cancer Center, Scottsdale, AZ
5Yale Univ. School of Med., New Haven, CT
6Division of Hematology, Mayo Clinic, Rochester, MN
7Washington University School of Medicine in Saint Louis, St. Louis, MO
8Division of Hematology and Oncology, Loyola University Medical Center, Maywood, IL
9University of Kansas Medical Center, Westwood, KS
10Hematology/Oncology, Mayo Clinic, Jacksonville, FL
11Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI
12MD Anderson Cancer Center, Houston, TX
13Roswell Park Comprehensive Cancer Center, Buffalo, NY
14University of Alabama at Birmingham, Birmingham, AL
15University of Nebraska Medical Center, Omaha, NE
16Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
17Ottawa Hospital, Ottawa, ON, CAN
18Translational Science and Therapeutics Division, Fred Hutch Cancer Research Center, Seattle, WA
19University of North Carolina, Chapel Hill, NC
20Holden Comprehensive Cancer Center, University of Iowa Hospital and Clinics, Iowa City, IA
21Weill Cornell Medical College, New York, NY
22Stony Brook University Cancer Center, Stony Brook, NY
23Hans Messner Allogeneic Transplant Program, Division of Medical Oncology and Haematology, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, ON, Canada
24Weill Cornell Medical Center, New York, NY
25Case Western Reserve University, Cleveland, OH
26Actinium Pharmaceuticals, New York, NY
27Actinium Pharmaceuticals, New York
28Fred Hutchinson Cancer Center, Clinical Research Division; University of Washington School of Medicine, Seattle, WA
29Loxo Oncology at Lilly, Stamford, CT
30Weill Cornell Medical College, Memorial Sloan Kettering Cancer Center, New York, NY
31Texas Oncology Baylor Charles A. Sammons Cancer Center, Dallas, TX

9:45 AM

Arpita Gandhi, MD1, Andrew Artz, MD, MS2, Catherine J. Lee, MD3, Ankur Varma, MD4, Bart L. Scott, MD5, Hye-Sook Kwon, PhD6*, Minyoung Youn, PhD7*, Chikako Yanagiba6*, Jeyakavitha Arulprakasam7*, Anne Le7*, Judith Shizuru, MD, PhD8*, Wendy W Pang, MD, PhD6 and Lori S. Muffly, MD9

1Division of Hematology/Medical Oncology, Knight Cancer Institute, Oregon Health and Science University, Portland, OR
2City of Hope, Duarte, CA
3Huntsman Cancer Institute, University of Utah, Salt Lake City, UT
4Rush University, Chicago, TX
5Fred Hutchinson Cancer Research Center, Seattle, WA
6Jasper Therapeutics, Redwood City, CA
7Jasper Therapeutics, Redwood City
8Stanford U Med Ctr, Stanford, CA
9Division of Blood and Marrow Transplantation & Cellular Therapy, Stanford University School of Medicine, Stanford, CA

10:00 AM

Hao Zheng1*, Meng Lv, MD, PhD1, Chenhua Yan, MD2*, Jing Liu, MD3*, Yuanyuan Zhang, MD4*, Xiao-Dong Mo, MD1*, Yuqian Sun, MD5*, Yu Wang, MD3*, Xiaohui Zhang5*, Lanping Xu, MD1* and Xiao-Jun Huang, MD6

1Peking University People's Hospital, Beijing, China
2Peking University People's Hosital, Beijing, China
3Peking University People’s Hospital, Beijing, China
4Peking University People’s hospital, Beijing, China
5Peking University People's Hospital, Peking University Institute of Hematology, Beijing, China
6Peking University People’s Hospital, Peking University Institute of Hematology, Beijing, China

10:15 AM

Noureddine Henoun Loukili1*, Luuk Gras Sr., MD, PhD2*, Linda Koster3*, Didier Blaise, MD, PhD4, Tobias Gedde-Dahl, MD5*, Johan Maertens, MD, PhD6*, Regis Peffault De Latour7,8,9,10,11,12,13,14,15*, Henrik Sengeloev16*, Stephan Mielke, MD17, Patrice Chevallier, MD18, Jakob R. Passweg, MD, MS19, Jenny Louise Byrne, MD, PhD20*, Urpu Salmenniemi21*, Anne Sirvent, MD22*, Denis Guyotat, MD23*, Simona Sica24*, Liesbeth C. de Wreede, PhD25*, Francesco Onida, MD26*, Christoph Scheid27*, Carmelo Gurnari, MD28,29, Joanna Drozd-Sokolowska, MD, PhD30*, Kavita Raj, MD, PhD31, Marie Robin, MD32*, Donal P McLornan, MD, PhD31* and Ibrahim Yakoub-Agha, MD, PhD33*

1CHU de Lille, Univ Lille, INSERM U1286, Infinite, 59000, Lille, AL, France
2EBMT Statistical Unit, Leiden, Netherlands
3EBMT Leiden Study Unit, Leiden, Netherlands
4Institut Paoli Calmettes, Marseille, FRA
5Oslo University Hospital, Oslo, NOR
6Department of Hematology, University Hospitals Leuven, Leuven, Belgium
7French Référence Center for Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria, Paris, France
8BMT Unit, Assistance Publique Hôpitaux de Paris, Université Paris Cité, Paris, France
9Hematology and Transplantation Unit, Hôpital Saint Louis, AP-HP, Paris, France
10Saint-Louis Hospital, Paris, France
11Hôpital Saint-Louis,, Paris, France
12Hopital St. Louis, Department of Hematology - BMT, Paris, France
13Hôpital Saint-Louis, Hematology Department, AP-HP, Paris, France
14Hôpital Saint-Louis, Paris, France
15French Reference Center for Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria, Paris, France
16Rigshospitalet, Copenhagen, Denmark
17Department of Cellular Therapy and Allogeneic Stem Cell Transplantation, Karolinska Institute & University Hospital, Stockholm, Stockholms Laen, Sweden
18CHU De NANTES, Nantes Cedex 1, France
19Department of Hematology University Hospital of Basel, Basel, Switzerland
20Nottingham University, Nottingham, ENG, GBR
21Turku University Hospital, Turku, FIN
22CHU Montpellier, Montpellier, France
23Institut de Cancerologie Lucien Neuwirth, CHU Saint Etienne, Saint Etienne, FRA
24Sezione di Ematologia, Dipartimento di Scienze Radiologiche ed Ematologiche, Università Cattolica del Sacro Cuore, Rome, Italy
25Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Netherlands
26Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico - University of, Milan, Italy
27University of Cologne, Cologne, Germany
28Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
29Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
30Central Clinical Hospital, The Medical University of Warsaw, Warsaw, Poland
31University College London Hospitals NHS Trust, London, United Kingdom
32Hopital Saint-Louis, Paris, France
33CHU de Lille, Univ Lille, INSERM U1286, Infinite, 59000, LILLE, FRA

10:30 AM

Marie Robin, MD1*, Simona Iacobelli, PhD2*, Jakob R. Passweg, MD, MS3, Linda Koster4*, Victoria Potter5*, Keith Wilson, FRCP, FRCPath6*, Urpu Salmenniemi7*, Dr. Dreger, MD, PhD8*, Peter von dem Borne Sr.9*, John Snowden, MD10*, Stephen Robinson Jr.11*, Maria Chiara Finazzi, MD12, Thomas Schroeder13*, Matthew P. Collin Sr., MD, PhD14, Matthias Eder15*, Edouard Forcade, MD, PhD16*, Michael Loschi, MD, PhD17*, Stefania Bramanti18*, Jose A. Perez-Simon, MD, PhD19*, Tomasz Czerw20*, Nicola Polverelli, MD21, Joanna Drozd-Sokolowska, MD, PhD22*, Kavita Raj, MD, PhD23, Juan Carlos Hernandez Boluda, MD, PhD24* and Donal P McLornan, MD, PhD23*

1Hopital Saint-Louis, Paris, France
2University of Rome Tor Vergata (Dept. of Biology), Rome, ITA
3Department of Hematology University Hospital of Basel, Basel, Switzerland
4EBMT Leiden Study Unit, Leiden, Netherlands
5Department of Haematological Medicine, King's College Hospital NHS, London, United Kingdom
6University Hospital of Wales, Cardiff, GBR
7Turku University Hospital, Turku, FIN
8University of Heidelberg, Heidelberg, Baden-Wuerttemberg, DEU
9Leiden University Medical Center, Leiden, Netherlands
10Sheffield Blood & Marrow Transplant and Cellular Theraphy Programme, Sheffield, United Kingdom
11University Hospitals Bristol, Bristol, GBR
12ASST Papa Giovanni XXIII and University of Milan, Bergamo, ITA
13Department of Hematology and Stem Cell Transplantation, University Hospital Essen, Essen, Germany
14Northern Centre for Bone Marrow Transplantation, Newcastle University, Newcastle Upon Tyne, GBR
15Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany
16Service d'Hématologie Clinique et Thérapie Cellulaire, CHU Bordeaux, F-33000, Bordeaux, France
17Centre Hospitalier Universitaire de Nice, Nice, France
18Humanitas Clinical and Research Center, IRCCS, Rozzano, Italy
19Department of Hematology, University Hospital Virgen del Rocio-IBIS. Universidad de Sevilla., Sevilla, Spain
20Maria Skłodowska-Curie National Research Institute of Oncology, Gliwice, POL
21Unit of Blood Diseases and Bone Marrow Transplantation, Department of Clinical and Experimental Sciences, University of Brescia, ASST Spedali Civili di Brescia, Brescia, Italy
22Central Clinical Hospital, The Medical University of Warsaw, Warsaw, Poland
23University College London Hospitals NHS Trust, London, United Kingdom
24Hospital Clínico Universitario-INCLIVA, Valencia, Spain

10:45 AM

Xiaoyu Zhang1*, Shulian Chen1*, Weihua Zhai1*, Yi He1*, Sizhou Feng2*, Mingzhe Han1*, Ting Niu, MD, PhD3, Yajing Xu, MD4*, Guangxun Gao5*, Shengjin Fan6*, Zepin Zhou, PhD7*, Fang Zhou8*, Rui Xi9*, Li Liu10*, Wei Yang, MD11*, Xi Zhang, PhD12, Qifa Liu, MD13 and Erlie Jiang, PhD1

1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences &Peking Union Medical College, Tianjin, China
2National Key Laboratory of Blood Science, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences &Peking Union Medical College, Tianjin, China
3West China Hospital Sichuan University, Chengdu, Sichuan, China
4Department of Hematoogy, Xiangya Hospital, Central South University, Changsha, China
5Department of Hematology, Xijing Hospital, Xi’An, China
6The First Affiliated Hospital of Harbin Medical University, Harbin, CHN
7Department of Hematology, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China, Kunming, China
8Department of Hematology, the 960th Hospital of the People's Liberation Army of China, Jinan, China
9The 940th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army, Lanzhou, China
10Department of Hematology, the Second Affiliated Hospital (Tangdu Hospital) of Air Force Medical University, Xi'an, China
11Shengjing Hospital of China Medical University, Shenyang, China
12Army medical University affiliated Xinqiao Hospital, Chongqing, China
13Nanfang Hospital, Southern Medical University, Guangzhou, China

*signifies non-member of ASH