-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
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721.O1.6 721. Allogeneic Transplantation: Conditioning Regimens, Engraftment and Acute Toxicities: Improving Outcomes by Reducing Transplant-Related Complications

Symposia: Allogeneic Transplantation: Conditioning Regimens, Engraftment and Acute Toxicities Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Biological therapies, Therapies, Transplantation
Saturday, December 9, 2023: 9:30 AM-11:00 AM
Room 11 (San Diego Convention Center)
Moderators:
Christina Cho, MD, John Theurer Cancer Center, Hackensack University Medical Center and Kris Michael Mahadeo, MD, Duke University Hospital
Disclosures:
Mahadeo: Jazz: Honoraria, Research Funding.
A major barrier to the success of allogeneic hematopoietic cell transplantation is early transplant-related morbidity and mortality. This session describes a novel method of risk-stratification of transplant candidates and unconventional approaches to selected, potentially serious complications.
9:30 AM

Andrew Artz, MD, MS1, Brent R. Logan, PhD2*, Wael Saber, MD, MS3, Nancy Geller, PhD4*, Anna Bellach, Ph.D.4*, Jianqun Kou, MS5*, William Wood, MD, MPH6, John M. McCarty, MD7, Thomas G. Knight, MD8, Lyndsey Runaas9*, Laura Johnston10, Jeremy Walston11*, Ryotaro Nakamura, MD12, Tammy Schuler13*, Asmita Mishra, MD, MBA14, Joseph Uberti, MD, PhD15, Parastoo B. Dahi, MD16*, Jennifer N. Saultz, DO17, Shannon R McCurdy, MD18, Lawrence Morris, MD19, Philip Imus, MD20, William J. Hogan, MD21, Kalyan Nadiminti, MBBS22, Vijaya Raj Bhatt, MD23, Deborah Mattila, BA24*, Bailey Protz25*, Steven M. Devine, MD26, Mary M. Horowitz, MD27 and Mohamed Sorror, MD, MSc28

1City of Hope, Duarte, CA
2Division of Biostatistics, Institute for Health and Equity, Medical College of Wisconsin, Milwaukee, WI
3Medical College of Wisconsin, Milwaukee, WI
4National Heart, Lung, and Blood Institute, Bethesda, MD
5CIBMTR® (Center for International Blood and Marrow Transplant Research), Department of Medicine, Medical College of Wisconsin, Milwaukee, WI
6Division of Hematology, Department of Medicine, University of North Carolina At Chapel Hill Hospital, Chapel Hill, NC
7Virginia Commonwealth University Medical Center, Richmond, VA
8Department of Hematologic Oncology and Blood Disorders, Atrium Health Levine Cancer Institute, Charlotte, NC
9Froedtert Hospital, Milwaukee, WI
10Stanford University, Stanford, CA
11Johns Hopkins University, Baltimore, MD
12Hematologic Malignancies and Stem Cell Transplantation Institute, City of Hope National Comprehensive Cancer Center, Duarte, CA
13Fred Hutchinson Cancer Research Center, Seattle, WA
14Moffitt Cancer Center, Tampa, FL
15Karmanos Cancer Institute/Wayne State University, Detroit, MI
16Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
17Oregon Health & Science University, Portland, OR
18Division of Hematology/Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, PA
19Blood and Marrow Transplant Program, Northside Hospital Cancer Institute, Atlanta, GA
20Johns Hopkins, Baltimore, MD
21Division of Hematology, Mayo Clinic, Rochester, MN
22Department of Medicine Division of Hematology, Medical Oncology and Palliative Care, University of Wisconsin–Madison, Madison, WI
23The Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE
24National Marrow Donor Program/Be The Match, Center for International Blood and Marrow Transplant Research, Minneapolis, MN
25National Marrow Donor Program/Be The Match, Center for International Blood and Marrow Transplant Research, Minnneapolis, MN
26Be the Match Foundation, Minneapolis, MN
27Center for International Blood and Marrow Transplant Research, Milwaukee, WI
28Fred Hutchinson Cancer Center, Seattle, WA

9:45 AM

Anita Lawitschka, anita.lawitschka@stanna.at1,2*, Jean-Hugues Dalle, MD, PhD3*, Ulrike Pötschger, PhD2*, Helga Arnardottir2*, Petr Sedlacek, MD, PhD4*, Jochen Büchner, MD, PhD5*, Marianne Ifversen, MD6*, Peter Svec, MD, PhD7*, Jerry Stein, MD8*, Tayfun Güngör, MD, PhD9*, Jacek Toporski, MD, PhD10*, Cristina Díaz De Heredia, MD11*, Marc Bierings, MD12, Roland Meisel, MD13*, Marc Ansari, MD, PhD14, Adriana Balduzzi, MD15,16, Franco Locatelli, MD, PhD17,18, Christina Peters, MD2,19* and Peter Bader, MD, PhD20

1St. Anna Children's Hospital, Vienna, Austria
2Children’s Cancer Research Institute, Vienna, Austria
3Pediatric Hematology and Immunology Department, GHU APHP Nord - Université Paris Cité, Robert Debré Hospital, Paris, France
4Department of Pediatric Hematology and Oncology, Motol University Hospital, Prague, Czech Republic
5Oslo University Hospital, Oslo, Norway
6Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
7Bone Marrow Transplantation Unit, Department of Pediatric Hematology and Oncology, National Institute of Children's Diseases, Comenius University, Bratislava, Slovakia
8Schneider Children's Medical Center of Israel and Sackler Faculty of Medicine Tel Aviv University, Petach Tikva, Israel
9University children’s Hospital, Zürich, Zürich, Switzerland
10Department Cell Therapy and Allogeneic Stem Cell Transplant (CAST), Karolinska University Hospital, Stockholm, Sweden
11Hospital Universitari Vall d’Hebron, Vall d’Hebron Institut de Recerca, Barcelona, Spain
12Princess Máxima Center, University Hospital for Children, Utrecht, Netherlands
13Division of Pediatric Stem Cell Therapy, Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich-Heine-University, Duesseldorf, Germany
14Geneva University Hospital, Geneva, Switzerland
15Pediatrics, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy
16School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy
17Catholic University of the Sacred Heart, Rome, Italy
18Department of Pediatric Hematology and Oncology, Sapienza University of Rome, IRCCS Ospedale Pediatrico Bambino Gesù, Roma, Italy
19Department of Pediatric Hematology and Oncology, St. Anna Children's Hospital, Vienna, Austria
20Department of Pediatrics, Division for Stem Cell Transplantation, Immunology and Intensive Care, Goethe University Frankfurt, University Hospital, Frankfurt, Germany

10:00 AM

Madhavi Lakkaraja, MD, MPH1,2, Audrey Mauguen, PhD3*, Kinga K Hosszu, PhD4*, Devin McAvoy, BS4*, Valerie Stewart, MSc, PhD5*, Gabrielle Schmidt, MPH5*, John Levine, MD6, Miguel-Angel Perales, MD7,8, Sergio A. Giralt, MD, FACP7,8, K. Scott Baker, MD, MS1,2 and Jaap Jan Boelens, MD9,10

1Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA
2Department of Pediatrics, Division of Hematology/Oncology, University of Washington School of Medicine, Seattle, WA
3Epidemiology-Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY
4Department of Pediatrics and Immune Discovery & Modeling Service, Memorial Sloan Kettering Cancer Center, New York, NY
5Center for International Blood and Marrow Transplant Research (CIBMTR), National Marrow Donor Program/Be The Match, Minneapolis, MN
6Icahn School of Medicine at Mount Sinai, New York, NY
7Department of Medicine, Weill Cornell Medical College, New York, NY
8Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
9Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY
10Department of Pediatrics, Weill Cornell Medicine, New York, NY

10:15 AM

Michael Grimley, MD1, Gabriela Maron, MD, MSc2*, Carlos A Gomez, MD3*, Vinod K. Prasad, MBBS, MD4*, Jasmeen Dara, MD, MS5*, Genovefa A Papanicolaou, MD6*, Koji Fukushima, MD, PhD7*, Robert F. Wynn, MRCP, MD, FRCPath8* and Michael Boeckh, MD9*

1Cincinnati Children's Hospital Medical Center, Cincinnati, OH
2St. Jude Children's Research Hospital, Memphis, TN
3University of Nebraska Medical Center, Omaha, NE
4PBMT Program, Durham, NC
5University of California, San Francisco, San Francisco, CA
6Memorial Sloan Kettering Cancer Center, New York, NY
7SymBio Pharmaceuticals Limited, Tokyo, Japan
8Royal Manchester Children's Hospital, Manchester, GBR
9Fred Hutchinson Cancer Center, Seattle, WA

10:30 AM

Eric Davis, MPH, CHTC1,2*, Elise Feuer3*, Candice Rapoport2*, Stephanie Lobaugh4*, Sean M. Devlin, PhD5*, Anne Archer1,2*, Stephanie Chinapen2*, Jacob Federman6*, Amanda Kelly2*, Elizabeth Klein1*, Melissa Nhaissi6*, Deborah Wells6*, Juliet N Barker, MBBS6,7, Esperanza B. Papadopoulos, MD6,8, Andromachi Scaradavou, MD1,9, Jaap Jan Boelens, MD1,9, Miguel-Angel Perales, MD6,8, Elena Maryamchik10* and Roni Tamari, MD6,8

1Pediatric Transplantation and Cellular Therapies Service, Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY
2Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York
3Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
4Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY
5Department of Biostatistics and Epidemiology, Memorial Sloan Kettering Cancer Center, New York, NY
6Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
7Department of Medicine, Weill Cornell Medicine, New York
8Department of Medicine, Weill Cornell Medicine, New York, NY
9Department of Pediatrics, Weill Cornell Medicine, New York, NY
10Transfusion Medicine and Cell Therapy, Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY

10:45 AM

Anthony Sabulski, MD1, Sonata Jodele, MD1, Eleanor Cook, MBBS1*, Kasiani Myers, MD2, Adam C. Lane, PhD3*, Samppa Ryhanen Sr., MD, PhD4, Maria Pia Cefalo5*, Francesco Quagliarella, MD5,6*, Stella M Davies, MBBS, PhD, MRCP1, Ashley Teusink-Cross1*, Paibel Aguayo-Hiraldo, MD7, Jessie L. Alexander, MD8, Paul Szabolcs, MD8, Mira Kohorst, MD9, Tiziana Corsetti5*, Franco Locatelli, MD, PhD5 and Pietro Merli, MD5,10*

1Cincinnati Children's Hospital Medical Center, Cincinnati, OH
2Cincinnati Children's Hospital, Cincinnati, OH
3Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
4Hospital For Children and Adolescent, Helsinki University Central Hospital, Helsinki, FIN
5Bambino Gesù Children's Hospital, Rome, Italy
6Department of Haematology-Oncology and Cell and Gene Therapy, Bambino Gesù Children Hospital, Rome, Italy
7Children's Hospital Los Angeles, Los Angeles, CA
8Children's Hospital of Pittsburgh, Pittsburgh, PA
9Mayo Clinic, Rochester, MN
10Hematology/Oncology, Cell and Gene Therapy, Bambino Gesù Children Hospital (IRCCS), Rome, Italy

*signifies non-member of ASH