-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

705.O4.6 705. Cellular Immunotherapies: Late Phase and Commercially Available Therapies: Translational Data and Prognostic Factors

Symposia: Cellular Immunotherapies: Late Phase and Commercially Available Therapies Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Research, Lymphoid Leukemias, ALL, Translational Research, Lymphomas, B Cell lymphoma, Diseases, aggressive lymphoma, Therapies, Lymphoid Malignancies
Saturday, December 9, 2023: 2:00 PM-3:30 PM
Room 6CF (San Diego Convention Center)
Moderators:
Jason Westin, MD, The University of Texas M D Anderson Cancer Center and Michael D. Jain, MD, PhD, Moffitt Cancer Center
Disclosures:
Westin: Kite/Gilead: Consultancy, Research Funding; Genentech: Consultancy, Research Funding; AstraZeneca: Consultancy, Research Funding; Morphosys/Incyte: Consultancy, Research Funding; ADC Therapeutics: Consultancy, Research Funding; Abbvie: Consultancy; SeaGen: Consultancy; Nurix: Consultancy; MonteRosa: Consultancy; Novartis: Consultancy, Research Funding; BMS: Consultancy, Research Funding; Calithera: Research Funding; Kymera: Research Funding. Jain: Kite/Gilead: Consultancy, Honoraria, Research Funding; Myeloid Therapeutics: Consultancy, Honoraria; Loxo@Lilly: Research Funding; Incyte: Research Funding.
This session includes translational and prognostic data from commercially available CAR T-cells.  This includes data regarding characteristics of the CAR T-cell product as well as biomarkers of response.
2:00 PM

Katie Maurer, MD, PhD1,2,3, Isabella N. Grabski, PhD4*, Roch Houot, MD, PhD5,6*, Satyen H Gohil1,7*, Shogo Miura1*, Robert A. Redd, MS8*, Haoxiang Lyu, BS1,9*, Wesley S Lu, BS1,9*, Brodie Miles, PhD10*, Mike Mattie, PhD11*, Yohei Arihara, MD, PhD1*, Mikaela M. McDonough, BS12*, Carol Reynolds, PhD12*, Michela Ansuinelli, MD12*, Shuqiang Li, PhD1,9*, Kenneth J. Livak, PhD1,9*, Jerome Ritz, MD1, Scott Rodig, MD, PhD13, Rafael A. Irizarry, PhD4,14*, Philippe Armand, MD, PhD1, Catherine J Wu, MD1,2,3 and Caron A Jacobson, MD, MMSc12

1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
2Harvard Medical School, Boston, MA
3Broad Institute of MIT and Harvard, Cambridge, MA
4Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA
5Centre Hospitalier Universitaire Rennes, Université de Rennes, Rennes Cedex, FRA
6CHU de Rennes, Rennes, France
7Haematology, University College Hospital, London, United Kingdom
8Department of Data Science, Dana-Farber Cancer Institute, Boston, MA
9Translational Immunogenomics Lab, Dana-Farber Cancer Institute, Boston, MA
10Kite Pharma, a Gilead Company, Santa Monica, CA
11Kite Pharma, a Gilead company, Santa Monica, CA
12Dana-Farber Cancer Institute, Boston, MA
13Department of Pathology, Brigham and Women's Hospital, Boston, MA
14Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA

2:15 PM

Sandeep Raj, MD1, Jin Xie, PhD2*, Teng Fei, PhD3*, Qinghua Song, PhD2*, Jenny J. Kim, MD, MS2, Christina To, MD2, Marcel R.M. van den Brink4, Miguel-Angel Perales, MD5, Mike Mattie, PhD2* and Roni Shouval, MD, PhD6

1Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY
2Kite Pharma, a Gilead company, Santa Monica, CA
3Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY
4Adult Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center, New York, NY
5Cellular Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY
6Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY

2:30 PM

Lara Stepan, BS1*, Sahar Ansari, PhD1*, Abood Okal, PhD2*, Justine Dell’Aringa, BS1*, Ethan Thompson, PhD1*, Alessandro Crotta, MD3*, Victor A Chow, MD1*, Jeremy S. Abramson, MD4, Manali Kamdar, MD5*, Jacob J. Chabon6*, Gregory Hogan, PhD6*, David M. Kurtz, MD, PhD7, Ash A. Alizadeh, MD, PhD8 and Leanne Peiser, DPhil1*

1Bristol Myers Squibb, Seattle, WA
2Bristol Myers Squibb, Princeton, NJ
3Celgene, a Bristol-Myers Squibb Company, Boudry, Switzerland
4Massachusetts General Hospital Cancer Center, Boston, MA
5University of Colorado Cancer Center, Aurora, CO
6Foresight Diagnostics, Aurora, CO
7Department of Medicine, Divisions of Oncology and Hematology, Stanford University, Stanford, CA
8Stanford Cancer Institute, Stanford University, Stanford, CA

2:45 PM

Mike Mattie, PhD1*, Melanie Grosso2*, Aurelie Auguste, PhD2*, Denis Arnaud, MBA2*, Frederick L. Locke, MD3, Sattva S. Neelapu, MD4, David B. Miklos, MD, PhD5, Caron A Jacobson, MD, MMSc6, Lazaros J. Lekakis7*, Yi Lin, MD, PhD8, Armin Ghobadi, MD9, Jenny J. Kim, MD, MS1, Jenny Nater1*, Rhine R. Shen, PhD10* and Jerome Galon2,11*

1Kite Pharma, a Gilead company, Santa Monica, CA
2Veracyte, Marseille, France
3Department of Blood and Marrow Transplantation and Cellular Immunotherapy, Moffitt Cancer Center, Tampa, FL
4Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
5Center for Cancer Cell Therapy, Stanford Cancer Institute, Stanford University, Stanford, CA
6Dana-Farber Cancer Institute, Boston, MA
7Sylvester Comprehensive Cancer Center, University of Miami Health System, Miami, FL
8Mayo Clinic Cancer Center, Rochester, MN
9Division of Oncology, Washington University School of Medicine, Saint Louis, MO
10Kite, a Gilead Company, Santa Monica, CA
11Universite de Paris, Centre de Recerche des Cordeliers, Equipe Labellisee Ligue Contre le Cancer, Laboratory of Integrative Cancer Immunology, INSERM, Sorbonne Universite, Paris, France

3:00 PM

Gloria Iacoboni, MD1*, Victor Navarro Garces2*, Josu Iraola1*, Pierre Sesques3*, Kai Rejeski, MD4, Fabio Serpenti, MD5*, Mariana Bastos-Oreiro6*, ANA Africa Martin Lopez, MD7*, Javier Delgado, MD8*, Ariadna Perez9*, Manuel Guerreiro, MD10*, Ana Carolina Caballero Gonzalez11*, Nuria Martinez-Cibrian, MD12*, Hugo Daniel Luzardo Henriquez, MD13*, Jose Maria Sanchez Pina14*, Juan-Manuel Sancho, MD, PhD15*, Herve Ghesquieres, MD3*, Alberto Mussetti, MD16*, Pere Barba, MD1, Lucia Lopez Corral, MD, PhD7*, Rafael Hernani9*, Juan Luis Reguera, MD8*, Anna Maria Sureda Balari, MD, PhD16, Francesc Bosch, MD, PhD1*, Alejandro Martin Garcia-Sancho, MD7*, Mi Kwon17, Andrea Kuhnl5*, Marion Subklewe, MD4, Emmanuel Bachy, MD, PhD18*, Guillermo Villacampa19* and Pau Abrisqueta Costa1*

1Vall d'Hebron University Hospital, Barcelona, Spain
2Oncology Data Science (ODysSey) Group, Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain
3Lyon Sud Hospital, Lyon, France
4LMU University Hospital, Munich, Germany
5King’s College Hospital NHS Foundation Trust, London, United Kingdom
6Hospital General Universitario Gregorio Marañón, Madrid, Spain
7Hospital Universitario de Salamanca, Salamanca, Spain
8University Hospital Virgen del Rocío, Sevilla, Spain
9Hospital Clínico Universitario, Valencia, Spain
10Hospital Universitario La Fe, Valencia, Spain
11Hematology Department, Hospital Santa Creu i Sant Pau, Barcelona, Spain
12Hospital Clinic Barcelona, Barcelona, Spain
13Hospital Universitario de Gran Canaria Doctor Negrín, Las Palmas de Gran Canaria, Spain
14Department of Hematology, Hospital Universitario 12 de Octubre, Madrid, Spain
15Hematology Department, ICO Badalona, Germans Trias i Pujol University Hospital. Universitat Autònoma de Barcelona. Josep Carreras Leukemia Research Institute, Barcelona, Spain
16Hospital Duran i Reynals (Institut Català d'Oncologia), Hospitalet de Llobregat, Barcelona, Spain
17General University Hospital Gregorio Marañón, Madrid, Spain
18Hematology Department, Lyon Sud Hospital, Pierre-Bénite, France
19Oncology Data Science Group, Vall D'Hebron Institute of Oncology. Barcelona, Spa, Barcelona, Spain

3:15 PM

Gloria Iacoboni, MD1*, Gilles Crochet, MD2*, Audrey Couturier, MD3*, Emmanuel Bachy, MD, PhD4*, Josu Iraola1*, Thomas Gastinne, MD5*, Charles Herbaux, MD, PhD6*, Tom Fradon7*, Mi Kwon8, Romain Gounot9*, Nuria Martinez-Cibrian, MD10*, Cristina Castilla-Llorente, MD11*, Manuel Guerreiro, MD12*, Clementine Sarkozy13*, Jose Aspa-Cilleruelo1*, Vincent Camus, MD14*, Stephanie Guidez15*, Adrien Chauchet16*, Eric Deconinck16, Krimo Bouabdallah, MD17*, Pere Barba, MD1, Roch Houot, MD, PhD3* and Franck Morschhauser18

1Vall d'Hebron University Hospital, Barcelona, Spain
2Hematology Department, CHU UCL Namur, Yvoir, Belgium
3CHU de Rennes, Rennes, France
4Hematology Department, Lyon Sud Hospital, Pierre-Bénite, France
5Hématologie, Hôpital Hôtel Dieu, Nantes Cedex 1, France
6Clinical Hematology Department, Montpellier University Hospital, MONTPELLIER, France
7LYSARC, Lyon, France
8General University Hospital Gregorio Marañón, Madrid, Spain
9Lymphoid Malignancies Unit, HôPital Universitaire Henri Mondor, Assistanc, CréTeil, FRA
10Hospital Clinic Barcelona, Barcelona, Spain
11Department of Hematology, Gustave Roussy Cancer Campus, Villejuif, France
12Hospital Universitario La Fe, Valencia, Spain
13Hematology department, Institut Curie, Saint Cloud, France
14Department of Hematology, Centre Henri Becquerel, Rouen, France
15Hematolgy department, University Hospital of Poitiers, Poitiers, France
16Besançon University Hospital, Besançon, France
17CHU Bordeaux Pessac, Bordeaux, FRA
18University of Lille, Centre Hospitalier Universitaire de Lille, Lille, AL, France

*signifies non-member of ASH