-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

704A.O1.6 704. Cellular Immunotherapies: Early Phase and Investigational Therapies: Improving CAR-T Therapies for B Cell Malignancies Clinically Relevant Abstract

Symposia: Cellular Immunotherapies: Early Phase and Investigational Therapies Program: Oral and Poster Abstracts
Type: Oral
Monday, December 11, 2023: 2:45 PM-4:15 PM
Room 6A (San Diego Convention Center)
Moderators:
Azra Borogovac, MD, and Jennifer N Brudno, MD, National Cancer Institute, National Institutes of Health
Disclosures:
Borogovac: Takeda Pharmaceutical: Honoraria. Brudno: Kyverna Therapeutics, Inc.: Other: unpaid position on Scientific Advisory Board.
2:45 PM

Liqing Kang1*, Jinfeng Ma2*, Xiaoyan Lou1*, Xiaowen Tang2*, Shengli Xue2*, Suning Chen2*, Huiying Qiu3*, Miao Miao2*, Yue Han2*, Ying Wang2*, Aining Sun2*, Haiping Dai2*, Yang Xu, M.D.4*, Limin Li5*, Shengjin Fan5*, Chongsheng Qian2*, Wenjie Gong2*, Mingzhu Xu2*, Haixia Zhou2*, Zhen Yao2*, Wei Wang1*, Minghao Li1*, Nan Xu1*, Zhou Yu1*, Depei Wu2,6 and Lei Yu1*

1Shanghai Unicar-Therapy Bio-Medicine Technology Co.,Ltd, Shanghai, China
2The First Affiliated Hospital of Soochow University, Suzhou, China
3Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China
4National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China
5Department of Hematology, The First Affiliated Hospital of Harbin Medical University,The Institute of The Hematology and Oncology of Heilongjiang Province, Harbin, China
6National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, Suzhou, China

3:00 PM

Robert Weinkove, PhD1,2*, Philip George, MBBS1,2*, Robert Fyfe, MBBS1,2*, Nathaniel Dasyam, PhD1*, Yasmin Nouri, PhD1,3*, Tess Ostapowicz1,4*, Stefan Mullins, MB BCh1,2*, Brigitta Mester, PhD1*, Giulia Giunti, PhD5,6*, Catherine M. Bollard, MD7, Travis Perera, MBBS2*, Hayden Jina, MD2*, Alwyn D'Souza, MBBS2*, Le Qin, PhD8*, David S. Ritchie, MD, PhD, FRACP, FRCPA9, Chris M.A. Frampton, PhD10*, Rachel Perret, PhD1*, Peng Li, PhD8,11* and Ian Hermans, PhD1*

1Cancer Immunotherapy Programme, Malaghan Institute of Medical Research, Wellington, New Zealand
2Te Rerenga Ora Wellington Blood & Cancer Centre, Te Whatu Ora Health New Zealand Capital Coast & Hutt Valley, Wellington, New Zealand
3Division of Immunology, The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia
4Clinical Trials Unit, Te Whatu Ora Health New Zealand Capital Coast & Hutt Valley, Wellington, New Zealand
5Clinical Human Immunology Laboratory, Malaghan Institute of Medical Research, Wellington, New Zealand
6BioOra, Wellington, New Zealand
7Children’s National Hospital, Washington, DC
8Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
9Department of Medicine, The University of Melbourne, Parkville, VIC, Australia
10Department of Medicine, University of Otago Christchurch, Christchurch, New Zealand
11Wellington Zhaotai Therapies Limited, Wellington, New Zealand

3:15 PM

Mingming Zhang1,2,3,4*, Yongxian Hu1,2,3,4*, Guoqing Wei2,3,4,5*, Shan Fu1*, Jingjing Feng1*, Ruimin Hong1*, Alex H. Chang6* and He Huang2,3,4,5*

1Bone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
2Institute of Hematology, Zhejiang University, Hangzhou, China
3Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy, Hangzhou, China
4Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou, China
5Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
6Shanghai YaKe Biotechnology Ltd, Shanghai, China

3:30 PM

Jae H. Park, MD1, Maria Lia Palomba, MD2, Sean M. Devlin, PhD3*, Yannis K. Valtis, MD1, Devanjan S Sikder4*, Brigitte Senechal4*, Xiuyan Wang, PhD4*, Elizabeth Cathcart5*, Kelly Liotta6*, Alina Yu6*, Kelsey Stocker6*, Honglei Zhang7*, Heiko Schoder, MD8*, Doris Leithner, MD9*, Jia Li10*, Leopold Sellner11*, Jorge Mansilla-Soto1*, Isabelle Riviere11* and Michel Sadelain, MD PhD12

1Memorial Sloan Kettering Cancer Center, New York, NY
2Cellular Therapy Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
3Department of Biostatistics and Epidemiology, Memorial Sloan Kettering Cancer Center, New York, NY
4Cell Therapy and Cell Engineering Facility, Memorial Sloan Kettering Cancer Center, New York, NY
5Cellular Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY
6Cellular Therapy Service, Memorial Sloan Kettering Cancer Center, New York
7Memorial Sloan Kettering Cancer Center, New York
8Molecular Imaging and Therapy Service, Memorial Sloan Kettering Cancer Center, New York
9Molecular Imaging and Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY
10Takeda Development Center Americas, Inc., Cambridge, MA
11Takeda Development Center Americas, Inc., Lexington, MA
12Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, NY

3:45 PM

Pierre Sesques1*, Roch Houot, MD, PhD2*, Yassine Al Tabaa, MD, PhD, PharmD3*, Fabien Le Bras, MD4*, Loic Ysebaert, MD, PhD5*, Fabrice Jardin, MD PhD6*, Choquet Sylvain7*, Jacques-Olivier Bay, MD, PhD8*, Francois Xavier Gros, MD9*, Franck Morschhauser, MD PhD10, Olivier Casasnovas11*, Thomas Gastinne, MD12*, Catherine Thieblemont, MD13*, Magalie Joris, MD14*, Laure Ricard, MD15*, Caroline Regny16*, Laurianne Drieu La Rochelle17*, Pierre Feugier18*, Ambroise Marcais, MD19*, Karin Tarte, PhD, PharmD20*, Camille Laurent, MD, PhD21* and Guillaume Cartron, MD, Ph-D22*

1CHU LYON SUD, PIERRE BENITE CEDEX, France
2Clinical Hematology, INSERM U1236, EFS, Hopital Pontchaillou, Rennes University Hospital, Rennes, France
3scintidoc, Montpellier, FRA
4Clinical Hematology, Henri-Mondor Hospital, Assistance Publique - Hôpitaux de Paris, Paris, FRA
5Hematology Department, Institut Universitaire du Cancer Toulouse Oncopole, Toulouse, France
6Centre Henri-Becquerel and University of Rouen, Rouen, France
7Hopital de la Pitié Salpetrière, APHP, Paris, FRA
8Service d’hématologie, CHU Clermont-Ferrand, Clermont-Ferrand, France
9CHU BORDEAUX, Merignac, FRA
10Hematology Department, Centre Hospitalier Régional Universitaire de Lille, Lille, AL, France
11CHU Dijon, Dijon, FRA
12CHU de Nantes, Nantes, France
13Hematology Department, Hôpital Saint-Louis, Paris, France
14Service d’Hématologie Clinique, Centre Hospitalier Universitaire Amiens-Picardie, Amiens, FRA
15APHP ST ANTOINE, PARIS, France
16CHU GRENOBLE ALPES, GRENOBLE, France
17CHU TOURS, Tours, FRA
18Henri Poincaré University, Vandoeuvre Les Nancy, FRA
19Hôpital Necker, AP-HP, PARIS, France
20CHU RENNES PONCHAILLOU, Rennes, FRA
21Institut Universitaire du Cancer , Oncopole, Toulouse, France
22Centre Hospitalier Universitaire de Montpellier, Montpellier, France

4:00 PM

Julio C. Chavez, MD1, Michael Dickinson, MBBS, D. Med Sci, FRACP, FRCPA2, Javier L. Munoz3, Matthew L. Ulrickson, MD4, Catherine Thieblemont, MD5*, Olalekan O. Oluwole, MBBS6, Alex F. Herrera, MD7, Chaitra S Ujjani, MD8, Yi Lin, MD, PhD9, Peter A. Riedell, MD10, Natasha K. Kekre, MD, MPH, FRCPC11*, Sven de Vos, MD, PhD12*, Christine Lui, MS13*, Jacob Wulff, DrPH13*, Chad M. Williams, PhD13*, Weixin Peng, MS13*, Ioana Kloos, MD13*, Hairong Xu, MD, PhD13* and Sattva S. Neelapu, MD14

1Moffitt Cancer Center, Tampa, FL
2Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia
3Banner MD Anderson Cancer Center, Phoenix, AZ
4Banner MD Anderson Cancer Center, Gilbert, AZ
5Service d'hémato-oncologie, Hôpital Saint-Louis, Paris, France
6Vanderbilt-Ingram Cancer Center, Nashville, TN
7City of Hope, Duarte, CA
8Clinical Research Division, Fred Hutch Cancer Center; and Division of Oncology, University of Washington, Seattle, WA
9Mayo Clinic Cancer Center, Rochester, MN
10David and Etta Jonas Center for Cellular Therapy, University of Chicago, Chicago, IL
11Department of Medicine, The Ottawa Hospital, Ottawa, ON, Canada
12David Geffen School of Med. at UCLA, Los Angeles, CA
13Kite, a Gilead Company, Santa Monica, CA
14Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX

*signifies non-member of ASH