Camila Guerrero, MSc^1*, Rosalinda Termini^2*, Juan-José Garcés, PhD^3*, Maria Jose Calasanz, PhD^4*, Rafael Ríos, MD, PhD^5*, Elena Cabezudo^6*, Laura Rosiñol, MD, PhD^7*, Bargay Joan^8*, Albert Pérez-Montaña, MD^9*, Albert Oriol Rocafiguera, MD^10*, Valentin Cabanas Perianes, MD^11*, Maria-Josefa Najera^12*, Esther Gonzalez Garcia, MD^13*, Enrique M Ocio, MD, PhD¹⁴, Anna Maria Sureda Balari, MD, PhD¹⁵, Felipe De Arriba, MD, PhD^16*, Miguel Teodoro Hernández Garcia, MD, PhD^17*, Antonio Garcia^18*, Joaquin Martinez-Lopez, MD, PhD^19*, María-Jesús Blanchard^20*, Marta Sonia Gonzalez Perez^21*, Rebeca Iglesias^22*, Alberto Orfao, MD, PhD^23*, Maria Victoria Mateos, MD, PhD²⁴, Juan Jose Lahuerta Palacios^25*, Joan Bladé, MD, PhD^26*, Jesus San-Miguel, MD, PhD²⁷, María T Cedena^28*, Noemi Puig, MD, PhD²⁹ and Bruno Paiva^30*

¹Cancer Center Clinica Universidad de Navarra (CCUN), Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IdiSNA), CIBER-ONC numbers CB16/12/00369 and CB16/12/00489, Pamplona, Spain
²Cancer Center Clinica Universidad de Navarra (CCUN), Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IdiSNA), CIBER-ONC numbers CB16/12/00369 and CB16/12/00489, Madrid, Spain, Pamplona, Spain
³Cancer Center Clinica Universidad de Navarra (CCUN), Pamplona, Spain
⁴CIMA LAB Diagnostics, Universidad de Navarra, Pamplona, Spain
⁵Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, Spain
⁶Hospital De Sant Joan Despí Moisès Broggi, Sant Joan Despí, Barcelona, ESP
⁷Amyloidosis and Multiple Myeloma Unit, Department of Hematology, IDIBAPS, Hospital Clinic, Barcelona, Spain
⁸Hospital Son Llazter, Palma de Mallorca, Spain
⁹Hospital Universitario Son Espases, Palma, Spain
¹⁰Institute of Oncology and Josep Carreras Institute, Hospital Germans Trias i Pujol, Badalona, Spain
¹¹Department of Hematology, IMIB-Virgen de la Arrixaca University Hospital. University of Murcia., Murcia, Spain
¹²Hospital Universitario San Pedro, Logroño, Spain
¹³University Hospital Cabueñes, Gijón, Spain
¹⁴Hospital Universitario Marques de Valdecilla, IDIVAL, Santander, Spain
¹⁵Hospital Duran i Reynals, Institut d’Investigacio Biomedica de Bellvitge (IDIBELL), Universitat de Barcelona, Barcelona, Spain, Barcelona, Spain
¹⁶Hospital Morales Meseguer, IMIB-Arrixaca, Universidad de Murcia, Murcia, Spain
¹⁷Hospital Universitario de Canarias, Tenerife, Spain
¹⁸Hospital Universitario Arnau de Vilanova, LLEIDA, ESP
¹⁹Department of Hematology, Hospital Universitario 12 de Octubre, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Complutense University, CNIO, CIBERONC, Madrid, Spain
²⁰Hematology, Hospital Universitario Ramon y Cajal, Madrid, Spain
²¹University Hospital of Santiago de Compostela, Santiago de Compostela, Spain
²²MD Anderson Cancer Center Madrid (Hospital MD Anderson Cancer Center Madrid), Madrid, ESP
²³Cancer Research Center (IBMCC-CSIC/USAL-IBSAL), Cytometry Service (NUCLEUS) and Department of Medicine, University of Salamanca, Salamanca, Spain
²⁴University Hospital of Salamanca/IBSAL/Cancer Research Center-IBMCC (USAL-CSIC), CIBERONC, Salamanca, Salamanca, Spain
²⁵Hospital Universitario 12 de Octubre, CIBER-ONC CB16/12/00369, CNIO, Madrid, Spain
²⁶Hematology Department, Hospital Clinic, IDIBAPS, Barcelona, Spain
²⁷CIMA (Pamplona)Cancer Center Clinica Universidad de Navarra (CCUN), Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IdiSNA), CIBER-ONC numbers CB16/12/00369 and CB16/12/00489, Pamplona, Spain
²⁸University Hospital 12 de octubre, Madrid, Spain
²⁹Hospital Universitario de Salamanca, Instituto de Investigacion Biomedica de Salamanca (IBSAL), University of Salamanca, Salamanca, Spain
³⁰Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada (CIMA), IDISNA, CIBER-ONC number CB16/12/00369 and CB16/12/00489, Pamplona, Spain

Elizabeth D. Lightbody, PhD^1,2,3, Romanos Sklavenitis-Pistofidis, MD^1,2,3, Danielle T. Firer, BS^2*, Junko Tsuji, PhD^2*, Mike P. Agius, PhD^1,2,3*, Ankit K. Dutta, PhD^1,2,3*, Ting Wu, MS^2*, Hadley Barr, BSc^1*, Sungjae Kim, PhD^2*, Tim Coorens, PhD^2*, Jean-Baptiste Alberge, PhD^1,2,3, Michelle P. Aranha, PhD^1,2,3*, Nicholas J Haradhvala, PhD^2*, Nang Kham Su, MSc^1*, Cody J. Boehner, BSc^1*, Kelly Walsh, PA-C^4*, Mahshid Rahmat, PhD^1,2,3*, Yoshinobu Konishi, MD, PhD^1,2,3, Laura Hevenor, BS^1*, Katherine Towle, BS^1*, Erica M. Horowitz, BA^1*, Jacqueline Perry, MPH^1*, Grace Fleming, BSc^1*, Habib El-Khoury, MD^1*, Michael Vinyard, BA^2*, Annie Cowan, BA^1*, Daniel Auclair, PhD⁵, John E. Ready, MD^3,4*, Catherine R. Marinac, PhD¹, Gad Getz, PhD^2,3,6* and Irene M. Ghobrial, MD^1,2,3

¹Dana-Farber Cancer Institute, Boston, MA
²Broad Institute of MIT and Harvard, Cambridge, MA
³Harvard Medical School, Boston, MA
⁴Department of Orthopaedic Surgery, Brigham and Women's Hospital, Boston, MA
⁵AstraZeneca, Waltham, MA
⁶Cancer Center, Massachusetts General Hospital, Boston, MA

Hua Wang, PhD^1*, Luz Yurany Moreno Rueda, PhD, MSc^1*, Minghao Dang, PhD^2*, Luz Yurany Moreno Rueda, PhD, MSc^3*, Hans Lee, MD¹, Krina K. Patel, MD, MSc⁴, Sheeba K. Thomas, MD⁵, Donna M. Weber, MD¹, Elisabet E. Manasanch, MD^1*, David E. Symer, MD, PhD¹ and Robert Z. Orlowski, MD, PhD^5,6

¹Department of Lymphoma & Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Lymphoma/ Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
⁴University of Texas MD Anderson Cancer Center, Houston, TX
⁵Department of Lymphoma/Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
⁶Department of Experimental Therapeutics, MD Anderson Cancer Center, Houston, TX

Anthony Cirrincione, PhD^1*, Marcella Kaddoura, M.D.^2*, Alexandra Maria Poos, PhD^3*, Bachisio Ziccheddu^2*, Kylee H Maclachlan, MBChB, PhD⁴, Monika Chojnacka, B.S.², Benjamin Diamond, M.D.^1*, Patrick Blaney, MS^5*, Dylan Gagler, B.S.^6*, Yanming Zhang, M.D.⁷, Ahmet Dogan, MD, PhD⁸, Alexander Lesokhin, MD⁴, Faith E. Davies, MD⁵, Hartmut Goldschmidt⁹, Katja Weisel, MD¹⁰, Roland Fenk, MD, PhD^11*, Elias K. Mai, M.D.^3*, Neha Korde, MD⁴, Gareth J. Morgan, M.D., Ph.D.^12*, Marc S. Raab, M.D.^13*, Saad Z Usmani, MD⁴, Ola Landgren, MD², Niels Weinhold, PhD^3* and Francesco Maura, MD²

¹Sylvester Comprehensive Cancer Center, Myeloma Division, University of Miami, Miami, FL
²Myeloma Service, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL
³Heidelberg Myeloma Center, Department of Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany
⁴Myeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
⁵Myeloma Research Program, NYU Langone, Perlmutter Cancer Center, New York, NY
⁶Perlmutter Cancer Center, Multiple Myeloma Research Program, NYU Grossman School of Medicine, NYU Langone Health, New York, NY
⁷Cytogenetics Laboratory, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY
⁸Department of Pathology and Laboratory Medicine, Hematopathology Service, Memorial Sloan Kettering Cancer Center, New York, NY
⁹University Clinic Heidelberg, Heidelberg, Germany
¹⁰Department of Oncology, Hematology and Bone Marrow Transplantation with Section of Pneumology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
¹¹Department of Hematology, Oncology and Clinical Immunology,, University Hospital Düsseldorf, Duesseldorf, Germany
¹²Myeloma Research Program, Perlmutter Cancer Center, NYU Langone Health, New York, NY
¹³Heidelberg Myeloma Center, Department of Medicine V, University Hospital Heidelberg, Heidelberg, Germany

Katia Beider^1*, Ilana Kalnitsky^1*, Nira Varda-Bloom, PhD^1*, Olga Ostrovsky, PhD^1*, Avichai Shimoni, MD^1*, Hila Magen, MD^1* and Arnon Nagler, MD²

¹Tel-Hashomer, Chaim Sheba Medical Center, Ramat-Gan, Israel
²Division of Hematology and Bone Marrow Transplantation, Chaim Sheba Medical Center, Tel Hashomer, Israel

Yubin Kang, MD¹, Xiaobei Wang, PhD^1*, Jian Wu, MD, PhD^1*, Shaima Jabbar, PhD^1*, Chongming Tom Jiang, PhD^2*, Xiling Shen, PhD^2* and Besim Ogretmen, PhD^3*

¹Division of Hematologic Malignancies and Cellular Therapy, Duke University, Durham, NC
²Terasaki Institute, Los Angeles, CA
³Departments of Biochemistry and Molecular Biology and Hollings Cancer Center, Medical University of South Carolina, Charleston, SC