Peter Hillmen, MB ChB, PhD¹, David Allan Cairns, PhD^2*, Adrian John Clifton Bloor, PhD, FRCPath, FRCP^3*, David Allsup, MD^4*, Kate Cwynarski, MBBS, PhD, FRCP, FRCPath^5*, Andrew Pettitt^6*, Shankaranarayana Paneesha, MD⁷, Christopher P. Fox, MD, PhD⁸, Toby A. Eyre^9*, Francesco Forconi, MD, PhD, DM, FRCPath^10*, Nagah Elmusharaf^11*, Ben Kennedy^12*, John G. Gribben, MD, DSc¹³, Nicholas Pemberton^14*, Oonagh Sheehy^15*, Gavin Preston, PhD, MBBS, FRCP, FRCPath^16*, Anna Schuh, MD, PhD, FRCP, FRCPath¹⁷, Dena Howard^18*, Anna Hockaday^18*, Sharon Jackson^18*, Natasha Greatorex^18*, Sean Girvan^18*, Sue Bell^18*, Julia Brown^19*, Nichola Webster^20,21*, Surita Dalal, PhD^20,21*, Ruth M de Tute, MSc, PhD, FRCPath^20*, Andrew Rawstron, PhD^22*, Piers EM Patten, FRCP, FRCPath, PhD^23,24 and Talha Munir, MBBS, MRCP, FRCPath, PhD^25*

¹Leeds Institute of Medical Research, St. James's University Hospital, Leeds, United Kingdom
²Leeds Institute of Clinical Trials Research, Cancer Research UK Clinical Trials Unit, Leeds, ENG, United Kingdom
³Haematology and Transplant Unit, Christie NHS Foundation Trust, Manchester, United Kingdom
⁴Castle Hill Hospital, Cottingham, GBR
⁵University College London, London, United Kingdom
⁶Royal Liverpool University Hospital, Liverpool, GBR
⁷Birmingham Heartlands Hospital, Birmingham, United Kingdom
⁸School of Medicine, University of Nottingham, Nottingham, United Kingdom
⁹Churchill Hospital, Oxford University, Oxford, United Kingdom
¹⁰Department of Haematology, Southampton University Hospital Trust, Southampton, United Kingdom
¹¹University Hospital of Wales, Cardiff, GBR
¹²Leicester Royal Infirmary, Leicester, GBR
¹³Barts Cancer Institute, Queen Mary University of London, London, United Kingdom
¹⁴Worcestershire Acute Hospitals NHS Trust, Worcester, United Kingdom
¹⁵Belfast Health & Social Care Trust, Belfast, GBR
¹⁶Aberdeen Royal Infirmary, Aberdeen, SCO, GBR
¹⁷Oxford National Institute for Health Research Biomedical Research Centre/Molecular Diagnostic Centre, University of Oxford, Oxford, United Kingdom
¹⁸Leeds Cancer Research UK Clinical Trials Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, United Kingdom
¹⁹Leeds Institute of Clinical Trials Research, University of Leeds, Leeds Cancer Research UK Clinical Trials Unit, Leeds, United Kingdom
²⁰HMDS, Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
²¹Leeds Institute of Medical Research, University of Leeds, Leeds, United Kingdom
²²Haematological Malignancy Diagnostic Service, Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
²³Comprehensive Cancer Centre, King’s College London, London, GBR
²⁴Department of Haematology, King’s College Hospital, London, GBR
²⁵Department of Haematology, St. James's University Hospital, Leeds, United Kingdom

Andy Rawstron, PhD^1*, Nichola Webster^1,2*, Surita Dalal, PhD^1,2*, Ruth M de Tute, MSc, PhD, FRCPath^1*, Sue Bell^3*, David Allan Cairns, PhD^3*, Sean Girvan^3*, Natasha Greatorex^3*, Anna Hockaday^3*, Sharon Jackson^3*, David Phillips^3*, David Stones^3*, David Allsup, MD^4*, Adrian John Clifton Bloor, PhD, FRCPath, FRCP^5*, Anita Sarma, MBBS^1*, Abraham Mullasseril Varghese, MBBS, MRCP^6*, Talha Munir, MBBS, MRCP, FRCPath, PhD^7* and Peter Hillmen, MB ChB, PhD⁸

¹HMDS, Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
²Leeds Institute of Medical Research, University of Leeds, Leeds, United Kingdom
³Leeds Cancer Research UK Clinical Trials Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, United Kingdom
⁴Castle Hill Hospital, Cottingham, GBR
⁵Haematology and Transplant Unit, Christie NHS Foundation Trust, Manchester, United Kingdom
⁶Department of Haematology, Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
⁷Department of Haematology, St. James's University Hospital, Leeds, United Kingdom
⁸Leeds Institute of Medical Research, St. James's University Hospital, Leeds, United Kingdom

Paolo Ghia, MD, PhD¹, William G. Wierda, MD, PhD², Paul M. Barr, MD³, Thomas J. Kipps, MD, PhD⁴, Tanya Siddiqi, MD^5*, John N. Allan, MD⁶, Zoë Hunter, PhD^7*, Cathy Zhou, MS^7*, Anita Szoke, MD^7*, James P. Dean, MD, PhD^8* and Constantine S. Tam, MD, MBBS^9*

¹Università Vita-Salute San Raffaele and IRCCS Ospedale San Raffaele, Milan, Italy
²The University of Texas MD Anderson Cancer Center, Houston, TX
³Wilmot Cancer Institute, University of Rochester, Rochester, NY
⁴UC San Diego Moores Cancer Center, Duarte, CA
⁵City of Hope National Medical Center, Duarte, CA
⁶Weill Cornell Medicine, Long Island City, NY
⁷AbbVie, North Chicago, IL
⁸Executive Medical Director and Global Development Lead, IMBRUVICA and Pediatrics (Oncology), AbbVie, North Chicago, IL
⁹Alfred Hospital and Monash University, Melbourne, VIC, Australia

Carol Moreno^1*, Talha Munir, MBBS, MRCP, FRCPath, PhD^2*, Carolyn Owen^3*, George Follows^4*, Jose-Angel Hernandez Rivas, MD^5*, Ohad Benjamini^6*, Ann Janssens, MD, PhD,^7*, Mark-David Levin, MD, PhD⁸, Tadeusz Robak^9*, Martin Simkovic, MD^10*, Sergey Voloshin, MD^11*, Vladimir I. Vorobyev, MD^12*, Munci Yagci^13*, Loic Ysebaert, MD, PhD^14*, Qianya Qi^15*, Emma Smith^15*, Srimathi Srinivasan^16*, Natasha Schuier^17*, Kurt Baeten^18*, Donne Bennett Caces^15*, Carsten Utoft Niemann, MD, PhD^19* and Arnon P. Kater, MD, PhD²⁰

¹Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona, Josep Carreras Leukaemia Research Institute, Barcelona, Spain
²Department of Haematology, St. James's University Hospital, Leeds, United Kingdom
³Tom Baker Cancer Centre, Calgary, Canada
⁴Addenbrookes Hospital, Cambridge, United Kingdom
⁵Hospital Universitario Infanta Leonor, Universidad Complutense, Madrid, Spain
⁶Sheba Medical Center–Tel HaShomer, Ramat Gan, Israel
⁷Universitaire Ziekenhuizen Leuven, Leuven, Belgium
⁸Albert Schweitzer Hospital, Dordecht, Germany
⁹Medical University of Lodz, Lodz, Poland
¹⁰4th Department of Internal Medicine – Haematology, Faculty of Medicine in Hradec Králové, University Hospital and Charles University in Prague, Hradec Kralove, Czech Republic
¹¹Russian Scientific and Research Institute of Hematology and Transfusiology, St Petersburg, Russian Federation
¹²S.P. Botkin Moscow City Clinical Hospital, Moscow, Russian Federation
¹³Gazi Universitesi Tip Fakultesi, Ankara, Turkey
¹⁴Hematology Department, Institut Universitaire du Cancer Toulouse Oncopole, Toulouse, France
¹⁵Janssen Research & Development, Raritan, NJ
¹⁶Oncology Translational Research, Janssen Research & Development, Lower Gwynedd Township, PA
¹⁷Janssen Research & Development, Dusseldorf, Germany
¹⁸Janssen Research & Development, Beerse, Belgium
¹⁹Department of Hematology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
²⁰Amsterdam University Medical Centers, Cancer Center Amsterdam, University of Amsterdam, Amsterdam, Netherlands

Moritz Fürstenau, MD^1*, Matthias Ritgen^2*, Sandra Robrecht, PhD^3*, Julia Von Tresckow, MD^4*, Can Zhang, PhD^5*, Anke Schilhabel^6*, Michael Gregor^7*, Patrick Thornton^8*, Philipp Bernhard Staber, MD, PhD⁹, Tamar Tadmor^10*, Vesa Lindström^11*, Gunnar Juliusson, MD, PhD¹², Ann Janssens, MD^13*, Mark-David Levin^14*, Caspar Da Cunha-Bang, MD, PhD^15*, Christof Schneider, MD^16*, Neta Goldschmidt^17*, Elisabeth Vandenberghe, MD¹⁸, Davide Rossi¹⁹, Rudolf A. Benz, MD²⁰, Daniel Heintel^21*, Christian Bjørn Poulsen^22*, Ilse Christiansen, MD, PhD^23*, Henrik Frederiksen, MD, PhD²⁴, Lisbeth Enggaard^25*, Eduardus Posthuma^26*, Djamila Issa^27,28*, Hein Visser^29*, Mar Bellido, MD, PhD^30*, Nadine Kutsch^31*, Jan Dürig^32*, Alexander Stehle^33*, Matthias C. Voehringer, MD^34*, Sebastian Böttcher^35*, Clemens Schulte^36*, Florian Simon, MD^37*, Anna-Maria Fink, MD^3*, Kirsten Fischer, MD^3*, Emily Holmes^38*, Karl-Anton Kreuzer^37*, Monika Brüggemann, MD^39*, Eugen Tausch, MD^40*, Stephan Stilgenbauer, MD⁴⁰, Michael Hallek, MD^41*, Arnon P. Kater, MD, PhD⁴², Carsten Utoft Niemann, MD, PhD^43* and Barbara F. Eichhorst, MD⁴⁴

¹Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf; German CLL Study Group, University of Cologne, Koeln, Germany
²Department II of Internal Medicine, University of Schleswig-Holstein, Kiel, Germany
³Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf; German CLL Study Group, University of Cologne, Cologne, Germany
⁴Clinic for Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
⁵German CLL Study Group, Cologne, NRW, DEU
⁶2nd Department of Internal Medicine, University of Schleswig-Holstein, Campus Ki, Kiel, DEU
⁷Division of Hematology, Cantonal Hospital of Lucerne, Lucerne, Switzerland, Luzern, CHE
⁸Department of Haematology, Beaumont Hospital, RCSI, Cancer Trials Ireland, Dublin, Dublin, IRL
⁹Department of Medicine I, Division of Hematology & Hemostaseology, Medical University of Vienna, Vienna, Austria
¹⁰Hematology, Bnai-Zion Medical Center, Haifa, Haifa, ISR
¹¹Comprehensive Cancer Center, Department of Hematology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland
¹²Lund Stem Cell Center Lund University & Hospital, Lund, Sweden
¹³University Hospitals Leuven, Leuven, Belgium
¹⁴Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, Dordrecht, NLD
¹⁵Rigshospitalet, Cohagenpen, DNK
¹⁶Division of CLL, Department of Internal Medicine III, University of Ulm, Ulm, Germany
¹⁷Department of Hematology, Hadassah Medical Center, Jerusalem, Jerusalem, ISR
¹⁸St. James's Hospital, Dublin, IRL
¹⁹Clinic of Hematology, Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland
²⁰Hematology, Muensterlingen, CHE
²¹Division of Medicine I, Klinik Ottakring, Vienna, Austria, Vienna, AUT
²²Department of Hematology, Zealand University Hospital, Roskilde, Denmark, Roskilde, DNK
²³Department of Hematology, Aalborg University Hospital, Aalborg, Denmark, Aalborg, DNK
²⁴Department of Hematology, Odense University Hospital, Odense, Denmark
²⁵Herlev Hospital, Herlev, DNK
²⁶Department of Internal Medicine, Reinier The Graaf Hospital, Delft, Delft, NLD
²⁷VU Medical Centre, Amsterdam, Amsterdam, NLD
²⁸Jeroen Bosch hospital, Den Bosch, Netherlands
²⁹Northwest Clinics, Alkmaar, NLD
³⁰Department of Hematology, University Medical Center Groningen, Groningen, NLD
³¹University of Cologne, Cologne, DEU
³²Department for Hematology and Stem Cell Transplantation, University Hospital Essen, Essen, Germany, Essen, DEU
³³Department of Hematology and Oncology, Robert-Bosch-Krankenhaus, Stuttgart, Stuttgart, Germany
³⁴Robert Bosch Krankenhaus, Onkologie, Stuttgart, Germany, DEU
³⁵Department of Medicine III Hematology, Oncology and Palliative Care, University Hospital, Rostock, Germany
³⁶Gemeinschaftspraxis für Hämatologie und Onkologie, Dortmund, Dortmund, DEU
³⁷Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf; German CLL Study Group, University of Cologne, Cologne, Cologne, DEU
³⁸German CLL Study Group, University of Cologne, Cologne, Cologne, Germany
³⁹Clinic for Internal Medicine II - Haematology, Oncology, University Clinic Schleswig-Holstein, Kiel, Germany
⁴⁰Department of Internal Medicine III, Division of CLL, Ulm University, Ulm, Germany
⁴¹Faculty of Medicine and Cologne University Hospital, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, University of Cologne, Cologne, Germany, Cologne, Germany
⁴²Department of Hematology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands
⁴³Department of Hematology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
⁴⁴University of Cologne, Cologne, Germany

Jeff P. Sharman, MD¹, Miklos Egyed, MD^2*, Wojciech Jurczak, MD, PhD³, Alan Skarbnik, MD⁴, Krish Patel, MD⁵, Ian W. Flinn, MD, PhD⁶, Manali Kamdar, MD^7*, Talha Munir, MBBS, MRCP, FRCPath, PhD^8*, Renata Walewska, MD, PhD^9*, Marie Hughes, MD¹⁰, Laura Maria Fogliatto, MD^11*, Yair Herishanu, MD^12*, Versha Banerji, MD¹³, George Follows^14*, Patricia A. Walker, MBBS, MD¹⁵, Karin Karlsson, MD^16*, Paolo Ghia, MD, PhD¹⁷, Ann Janssens, MD^18*, Florence Cymbalista, MD, PhD^19*, John C. Byrd, MD²⁰, Emmanuelle Ferrant, MD^21*, Alessandra Ferrajoli, MD²², William G. Wierda, MD, PhD²³, Veerendra Munugalavadla, PhD²⁴, Catherine Wangui Wachira, MS, MBA^25*, Chuan-Chuan Wun, PhD^24* and Jennifer A. Woyach, MD^20*

¹Willamette Valley Cancer Institute and Research Center/US Oncology Research, Eugene, OR
²Somogy County Mór Kaposi General Hospital, Kaposvár, Hungary
³Maria Sklodowska-Curie National Research Institute of Oncology, Krakow, Poland
⁴Novant Health Cancer Institute, Charlotte, NC
⁵Swedish Medical Center, Seattle, WA
⁶Sarah Cannon Research Institute, Tennessee Oncology, Nashville, TN
⁷University of Colorado Cancer Center, Aurora, CO
⁸Haematology, Haematological Malignancy Diagnostic Service (HMDS), St. James’s Institute of Oncology, Leeds, United Kingdom
⁹Cancer Care, University Hospitals Dorset, Bournemouth, United Kingdom
¹⁰Tauranga Hospital, Tauranga, New Zealand
¹¹Hospital das Clínicas de Porto Alegre. Porto Alegre, Rio Grande do Sul – Brazil, Porto Alegre, Brazil
¹²Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel
¹³Departments of Internal Medicine, Biochemistry & Medical Genetics, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba and CancerCare Manitoba, Winnepeg, Canada
¹⁴Department of Haematology, Addenbrooke’s Hospital NHS Trust, Cambridge, United Kingdom
¹⁵Peninsula Health and Peninsula Private Hospital, Frankston, Melbourne, AUS
¹⁶Skåne University Hospital, Lund, Sweden
¹⁷Università Vita-Salute San Raffaele and IRCCS Ospedale San Raffaele, Milano, Italy
¹⁸University Hospitals Leuven, Leuven, Belgium
¹⁹Bobigny: Hématologie, CHU Avicennes, Bobigny, France
²⁰The Ohio State University Comprehensive Cancer Center, Columbus, OH
²¹Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Service d’Hématologie Clinique, Pierre-Bénite, France
²²Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²³University of Texas MD Anderson Cancer Center, Houston, TX
²⁴AstraZeneca, South San Francisco, CA
²⁵AstraZeneca, New York, NY