-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

634A.O2.6 634. Myeloproliferative Syndromes: Clinical and Epidemiological: Rare Myeloproliferative Neoplasms: Unveiling Promising Pathways and Novel Therapies Clinically Relevant Abstract

Symposia: Myeloproliferative Syndromes: Clinical and Epidemiological Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Research, clinical trials, Biological therapies, adult, epidemiology, Translational Research, MPN, Non-Biological therapies, Clinical Research, genomics, Chronic Myeloid Malignancies, drug development, pediatric, Diseases, Therapies, registries, Myeloid Malignancies, Pharmacology, Biological Processes, molecular biology, Study Population, Human
Saturday, December 9, 2023: 9:30 AM-11:00 AM
Ballroom 20AB (San Diego Convention Center)
Natasha Szuber, MD, MSc, Mayo Clinic and Aaron T. Gerds, MD, MS, Cleveland Clinic Taussig Cancer Institute
Gerds: AbbVie, Bristol Myers Squibb, Constellation Pharmaceuticals, GlaxoSmithKline, Kartos, Novartis, PharmaEssentia, Sierra Oncology: Consultancy; Accurate Pharmaceuticals, Constellation Pharmaceuticals, CTI BioPharma, Imago BioSciences, Incyte Corporation, Kratos Pharmaceuticals: Research Funding.
This session spotlights new clinical data and exciting therapeutic breakthroughs in uncommon myeloproliferative neoplasms. Together, these data will delineate the new therapeutic landscape of these rare diseases as it shifts from from desert island to promising new possibilities.
9:30 AM

Andrew T. Kuykendall, MD1, Kristen Marie Pettit, MD2, Abhay Singh, MD, MPH3, Tania Jain, MD4, David A Sallman, MD5, Qianxing Mo, PhD1*, Quan Lovette1*, Ling Zhang, MD6, Onyee Chan, MD7, Alison R. Walker, MD, MPH, MBA1, Zhuoer Xie, MD, MS8, Jeffrey Lancet, MD7, Maria Balasis1*, Seongseok Yun, MD, PhD7, Eric Padron, MD7 and Rami S. Komrokji, MD7

1Moffitt Cancer Center, Tampa, FL
2Rogel Cancer Center, University of Michigan, Ann Arbor, MI
3Department of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, OH
4The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, Baltimore, MD
5H. Lee Moffitt Cancer Center, Tampa, FL
6Department of Pathology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL
7Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL
8H. Lee Moffitt Cancer Institute, Tampa, FL

9:45 AM

Elliot Stieglitz, MD1, Alex Lee, PhD1*, Steven P. Angus, PhD2*, Christopher Davis2*, Donald Barkauskas, PhD3,4*, David Hall3*, Scott C. Kogan, MD1, Julia Meyer, PhD1*, Steven D. Rhodes, MD, PhD5*, Xiaoling Xuei, PhD5*, Kevin Shannon, MD6*, Mignon L. Loh, MD7, Elizabeth Fox, MD8* and Brenda J. Weigel, MD, MSc9

1University of California, San Francisco, San Francisco, CA
2Indiana University, Indianopolis, IN
3Children’s Oncology Group Operations Statistics and Data Center, Monrovia, CA
4Department of Population and Public Health Sciences, Keck School of Medicine of the University of Southern California, Los Angeles, CA
5Indiana University, Indianapolis, IN
6Department of Pediatrics, University of California, San Francisco, San Francisco, CA
7Ben Towne Center for Childhood Cancer Research, Seattle Children’s Hospital, Seattle, WA
8St. Jude Children's Research Hospital, Memphis, TN
9University of Minnesota, Minneapolis, MN

10:00 AM

Sudipto Mukherjee, MD, PhD, MPH1, Doug J Cattie2*, Daniel Shaheen, PharmD2*, Dakota Powell, MPH2* and Teresa Green, MSPH2*

1Department of Hematology and Medical Oncology, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH
2Blueprint Medicines Corporation, Cambridge, MA

10:15 AM

Tsewang Tashi, MD1, Olivier Hermine, MD, PhD2, Mariana Castells, MD, PhD3*, Mar Guilarte, MD, PhD4*, Vito Sabato, MD, PhD5*, Marcus Maurer, MD6*, Jens Panse, MD7, Ivan Alvarez-Twose, MD, PhD8*, Renata Cabral, MD9*, Robert Bird, MBBS10*, Stéphane Barete, MD, PhD11*, Laurence Bouillet, MD, PhD12*, Maud Hermans, MD, PhD13*, Paul Van Daele, MD, PhD14*, David González-De-Olano, MD, PhD15*, Elizabeth A. Griffiths, MD16, Joseph Jurcic, MD17, Ingunn Dybedal, MD, PhD18, Gandhi Laurent Damaj, MD, PhD19*, Philippe Schafhausen20*, Chiara Elena, MD21*, Tse-Chieh Teh, MD, PhD22*, Pankit Vachhani, MD23*, Caroline Labe, BA24*, Saranya Venugopal, MS, MPharm24*, Kevin He, PhD24*, Javier Muñoz-González, PhD25*, Ben Lampson, MD, PhD24*, Robyn Scherber, MD24*, Prithviraj Bose, MD26, Clive Grattan, MD27*, Thanai Pongdee, MD28, Tracy I. George, MD29 and Cristina Bulai Livideanu30*

1University of Utah, Huntsman Cancer Institute, Salt Lake City, UT
2Département d'hématologie, CEREMAST, Hôpital Necker-Enfants Malades, APHP et Institut Imagine, Paris, France
3Department of Medicine, Division of Allergy and Clinical Immunology, Brigham and Women’s Hospital, Boston, MA
4Hospital Universitari Vall d'Hebron, Institut de Recerca (VHIR), Barcelona, Spain
5Department of Immunology, Allergology and Rheumatology, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium
6Charité – Universitätsmedizin Berlin and Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology Hindenburgdamm, Berlin, Germany
7University Hospital Aachen, Medical Faculty, RWTH Aachen University, Aachen, Germany
8Institute of Mastocytosis Studies of Castilla-La Mancha (CLMast), Virgen del Valle Hospital, Toledo, Spain
9Centro Hospitalar Universitário do Porto and ICBAS-School of Medicine and Biomedical Sciences, University of Porto, Porto, Portugal
10Princess Alexandra Hospital, Woolloongabba, Australia
11AP-HP, Pitié-salpêtrièRe Hospital, University Pierre & Mari, Paris, France
12CHU Grenoble Alpes, Grenoble, France
13Department of Allergology and Clinical Immunology Section of Clinical Immunology, Internal Medicine, Erasmus MC University Medical Centre, Rotterdam, Netherlands
14Erasmus Medical Center, Rotterdam, Netherlands
15University Hospital Ramón y Cajal, IRYCIS, Madrid, Spain
16Roswell Park Comprehensive Cancer Center, Buffalo, NY
17Columbia University Medical Center, New York, NY
18Oslo University Hospital, Rikshospitalet, Oslo, Norway
19Hematology Institute, University Of Caen Normandie Hospital Center, Caen, France
20University Medical Center Hamburg-Eppendorf, Hamburg, Germany
21Department of Molecular Medicine & Department of Hematology and Oncology, University of Pavia, Pavia, Italy
22Alfred Hospital, Melbourne, Australia
23University of Alabama at Birmingham, Birmingham, AL
24Blueprint Medicines Corporation, Cambridge, MA
25Blueprint Medicines Corporation, Zug, Switzerland
26The University of Texas MD Anderson Cancer Center, Houston, TX
27St John's Institute of Dermatology, Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom
28Division of Allergic Diseases, Mayo Clinic, Rochester, MN
29ARUP Laboratories, University of Utah School of Medicine, Salt Lake City, UT
30Department of Dermatology, CEREMAST Toulouse, CHU Toulouse, Toulouse, France

10:30 AM

Prithviraj Bose, MD1, Stephen T. Oh, MD, PhD2, Brian Modena, MD3*, Anthony M. Hunter, MD4*, Cem Akin, MD, PhD5*, Mariana Castells, MD, PhD6*, Michael Manning, MD7*, Richard Herrscher8*, Frank Siebenhaar, MD9*, Daniel J. DeAngelo10, Tracy I. George, MD11, Benjamin Exter, PharmD12*, Jenna Zhang, PhD12*, Amanda Pilla12*, Hina Jolin, PharmD12*, Rachael Easton, MD, PhD12* and Lindsay A.M Rein, MD13

1The University of Texas MD Anderson Cancer Center, Houston, TX
2Department of Medicine, Washington University School of Medicine, Saint Louis, MO
3Modena Allergy & Asthma, San Diego, CA
4Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta
5University of Michigan, Ann Arbor, MI
6Department of Medicine, Division of Allergy and Clinical Immunology, Brigham and Women’s Hospital, Boston, MA
7Allergy, Asthma, & Immunology Associates, Scottsdale
8AirCare, Plano
9Charité - UniversitäTsmedizin Berlin, Berlin, DEU
10Dana-Farber Cancer Institute, Boston, MA
11ARUP Laboratories, University of Utah School of Medicine, Salt Lake City, UT
12Cogent Biosciences, Waltham, MA
13Duke University, Durham, NC

10:45 AM

Matthieu Groh, MD, MSc1*, Laurène Fenwarth, MD, MSc2*, Augustin Boudry2*, Elise Fournier3*, Alice Marceau-Renaut, PharmD4*, Julie Abraham5*, Marly Barry6,7*, Philippe Blanche, MD8*, Quentin Bodard9*, Thorsten Braun, MD, PhD10,11, Safia Chebrek12*, Rafael Daltro De Oliveira, MD13*, Matthieu Decamp, MD, PhD14*, Cécile Audrey Durel15*, Edouard Forcade, MD, PhD16*, Mathieu Gerfaud-Valentin17*, Camille Golfier18*, Clement Gourguechon19*, Nathalie Grardel20*, Olivier Kosmider, MD, PhD21*, Mathilde Labro22*, Sarah Melboucy Belkhir23*, Fatiha Merabet24*, Adrien Michon25*, Nihal Martis26*, Cécile Morice27*, Stephane Moreau28*, Antoine Néel29*, Franck E. Nicolini, MD, PhD30, Laurent Pascal31*, Florence Pasquier, MD, PhD32*, Andrea Pieragostini33*, Catherine Roche-Lestienne34*, Philippe Rousselot, MD, PhD35*, Anne Thiebaut, MD36*, Jean-Francois Viallard, MD PhD37*, Mathieu Wemeau38*, Claude Preudhomme, PharmD, PhD39*, Jean-Emmanuel Kahn40*, Guillaume Lefèvre41* and Nicolas Duployez, PharmD, PhD39,42*

1French National Reference Center for Hypereosinophilic Syndromes (CEREO), Departement of Internal Medicine, Hôpital Foch, Suresnes, France
2Hematology Laboratory, CHU Lille, Lille, France
3University Hospital, Lille, LILLE, FRA
4Hematology Laboratory, CHU Lille, Lille Cedex, FRA
6CH de Boulogne sur Mer, Boulogne-sur-Mer, TX, FRA
7CH Du Docteur Duchenne, Boulogne Sur Mer Cedex, FRA
8Department of Internal Medicine, CHU Cochin, Paris, France
9CH d'Angoulême, Angoulême, France
10Clinical Hematology, Avicenne University Hospital, Assistance Publique – Hôpitaux de Paris, Bobigny, France
11Hematology Department, Avicenne Hospital, Bobigny, France
12CH d'Avignon, Avignon, FRA
13Centre d'Investigation Clinique, Hôpital St Louis, Paris, France
15Hôpital St Joseph St Luc, Lyon, FRA
16Service d'Hématologie Clinique et Thérapie Cellulaire, CHU Bordeaux, Pessac, France
17Hôpital de la Croix Rousse, Lyon, France
18Hôpital Lyon Sud, Lyon, France
19Amiens University Hospital, Amiens, France
21Cochin Hospital, Paris, FRA
22Department of Clinical Research and Innovation, Hôpital Foch, Suresnes, France
23CH de St Quentin, St Quentin, France
24andre mignot hospital, LE CHESNAY, FRA
25Hôpital Européen Georges Pompidou, Paris, FRA
26CHU De Nice, Nice, FRA
27Dermatology, CHU de Caen, Caen, France
28Hématologie Clinique, CHU Limoges, Limoges, FRA
29CHU Hôtel-Dieu, Nantes, FRA
30Hematology Department, Centre Leon Berard, Lyon, France
31Faculté Catholique De Lille, Lille, FRA
32INSERM U790, PR1, IGR, Villejuif, FRA
33Hematology, CHU Dijon, Dijon, France
34CHU Lille, Lille, France
35Centre Hospitalier de Verailles, UMR1184, University Versailles Paris-Saclay, Versailles, France
36CHU Grenoble, Grenoble, France
37Service Médecine Interne, Haut-Leveque Hospital, Pessac, France
38CH Valenciennes, Valenciennes, FRA
39Laboratory of Hematology, Centre Hospitalier Universitaire (CHU) Lille, Lille, France
40CHU Ambroise Paré, Boulogne Billancourt, FRA
41Laboratoire d'Immunologie, CHU de Lille, Lille, France
42Hôpital Claude Huriez, Lille, France

*signifies non-member of ASH