Description:
This joint session between the subcommittees on lymphoid neoplasia and hematopathology will investigate four different areas of study that can teach us about how lymphoma develops and provide insights into new or improved therapeutic strategies.
Dr. Aswin Sekar will discuss his work on clonal hematopoiesis and precursor mutations as it relates to the development of lymphoid neoplasms, so-called L-CHP, and what it may teach us about the precursor genetic events that increase one's risk of developing lymphoma.
Dr. Laura Pascqualucci will relate aberrant germinal center expansion with the process of lymphomagenesis in discussing her work related to epigenetic alterations and key genetic mutations that play a role in germinal centers gone wrong.
Dr. Christian Munz is an infectious disease specialist with an expertise in EBV infection and EBV related lymphomagenesis and will discuss what we know about viral oncogenesis and how it can be applied to our understanding on non-viral causes of lymphoma evolution.
Dr. Mandeep Singh studies autoimmunity and has identified lymphoma driver mutations associated with the development of rheumatoid factor autoantibodies and will discuss the intersections between autoimmunity and lymphomagenesis and how the abnormal immune response in autoimmune diseases may be relevant to the development of lymphoid neoplasms and to their therapies.
Dr. Aswin Sekar will discuss his work on clonal hematopoiesis and precursor mutations as it relates to the development of lymphoid neoplasms, so-called L-CHP, and what it may teach us about the precursor genetic events that increase one's risk of developing lymphoma.
Dr. Laura Pascqualucci will relate aberrant germinal center expansion with the process of lymphomagenesis in discussing her work related to epigenetic alterations and key genetic mutations that play a role in germinal centers gone wrong.
Dr. Christian Munz is an infectious disease specialist with an expertise in EBV infection and EBV related lymphomagenesis and will discuss what we know about viral oncogenesis and how it can be applied to our understanding on non-viral causes of lymphoma evolution.
Dr. Mandeep Singh studies autoimmunity and has identified lymphoma driver mutations associated with the development of rheumatoid factor autoantibodies and will discuss the intersections between autoimmunity and lymphomagenesis and how the abnormal immune response in autoimmune diseases may be relevant to the development of lymphoid neoplasms and to their therapies.