denotes an abstract that is clinically relevant.
denotes that this is a recommended PHD Trainee Session.
denotes that this is a ticketed session.Session: Hemostasis in Patients With Severe Liver Disease
Hematology Disease Topics & Pathways:
Research, clinical trials, Bleeding and Clotting, adult, epidemiology, Clinical Research, thromboembolism, Diseases, real-world evidence, thrombotic disorders, Therapies, registries, Adverse Events, Study Population, Human
Disclosures: Ageno: BMS-Pfizer: Honoraria; Viatris: Honoraria; Norgine: Honoraria; Bayer: Honoraria, Research Funding; Sanofi: Honoraria.
OffLabel Disclosure: The talk will initially focus on the association between liver disease, in particular liver cirrhosis, and splanchnic vein thrombosis. Challenges in the initial management of patients with liver cirrhosis presenting with splanchnic vein thrombosis, with particular focus on patients presenting with gastrointestinal bleeding or at high risk of bleeding because of thrombocytopenia and/or esophageal varices will be discussed. Finally, the talk will review the available evidence on the risks and benefits of anticoagulant therapy in this setting, with a particular focus on recent evidence on the role of direct oral anticoagulants.