-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

Late-Breaking Abstracts Session

PhD Trainee
Program: General Sessions
Tuesday, December 13, 2022: 9:00 AM-10:30 AM
Hall E (Ernest N. Morial Convention Center)
Co-chairs:
David A. Garcia, MD, University of Washington and Olatoyosi Odenike, MD, University of Chicago
Disclosures:
No relevant conflicts of interest to declare.
This highly anticipated session highlights the Joint Program Committees' selections of the highest-impact abstracts, featuring substantive, novel, and groundbreaking data that were not available by the general abstract submission deadline and would otherwise not be presented at the ASH annual meeting.

Mark R. Litzow, MD1, Zhuoxin Sun, PhD2*, Elisabeth Paietta, PhD3, Ryan J. Mattison, MD4, Hillard M Lazarus, MD5, Jacob M. Rowe, MB, BS6, Daniel A. Arber, MD7, Charles G. Mullighan, MBBS, MD8, Cheryl L Willman, MD9, Yanming Zhang, MD10, Matthew Wieduwilt, MD11*, Michaela Liedtke, MD12, Julie Bergeron, MD13, Keith W. Pratz, MD14, Shira Dinner, MD15, Noelle V. Frey, MD, MS16, Steven D. Gore, MD17, Bhavana Bhatnagar, DO18, Ehab L. Atallah, MD19, Geoffrey L. Uy, MD20, Deepa Jeyakumar, MD21, Tara L. Lin, MD22, Richard F. Little, MD, MPH23, Selina M. Luger, MD, FRCPC24 and Martin S. Tallman, MD25

1Division of Hematology, Mayo Clinic, Rochester, MN
2Dana-Farber Cancer Institute, Boston, MA
3Cancer Center, Montefiore Medical Center, Bronx, NY
4Carbone Comprehensive Cancer Center, Madison, WI
5Adult Hematologic Malignancies & Stem Cell Transplant Section, University Hospitals Cleveland Medical Center, Shaker Heights, OH
6Department of Hematology, Shaare Zedek Medical Center, Jerusalem, Israel
7Department of Pathology, The University of Chicago, Chicago, IL
8Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN
9Mayo Clinic, ROCHESTER, MN
10Department of Pathology and Laboratory Medicine, Cytogenetics Laboratory, Memorial Sloan Kettering Cancer Center, New York, NY
11Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK
12Department of Medicine, Divisions of Oncology and Hematology, Stanford University, Stanford, CA
13CEMTL installation Maisonneuve-Rosemont, Montreal, QC, Canada
14Department of Medicine, Hematology-Oncology Section, Hospital of the University of Pennsylvania, Philadelphia, PA
15Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL
16Abramson Cancer Center, University of Pennsylvania, Narberth, PA
17Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, MD
18Department of Hematology and Medical Oncology, West Virginia University Cancer Institute, Wheeling, WV
19Division of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI
20Division of Oncology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO
21Division of Hematology/Oncology, UC Irvine Medical Center, Orange, CA
22University of Kansas, Westwood, KS
23National Cancer Institute, Washington, DC
24Cellular Therapy and Transplantation, Abramson Cancer Center of the University of Pennsylvania, Philadelphia, PA
25Robert H. Lurie Comprehensive Cancer Center, Northwestern University and ECOG, Chicago, IL

Regis Peffault De Latour1,2*, Alexander Roeth, MD3, Austin Kulasekararaj, MD, MBBS, FRCPath, MRCP4,5,6, Phillip Scheinberg, MD7, Yasutaka Ueda, MD, PhD8, Carlos M de Castro, MD9, Eros Di Bona, MD10*, Hubert Schrezenmeier, MD11,12, Saskia MC Langemeijer, MD, PhD13*, Wilma Barcellini, MD14*, Suzanne Tavitian, MD15*, Jens Panse, MD16, Philippe Schafhausen, MD17*, Vitor AQ Mauad, MD18*, Cecile Kerloeguen, MSc19*, Rafael Levitch, MD19*, Rakesh Kumar20*, Christine Thorburn21*, Samopriyo Maitra20*, Marion Dahlke, MD19* and Antonio M Risitano, MD, PhD22,23

1French Référence Center for Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria, Paris, France
2BMT Unit, Assistance Publique Hôpitaux de Paris, Université Paris Cité, Paris, France
3West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany
4King's College London, London, United Kingdom
5King's College Hospital NHS, London, United Kingdom
6National Institute for Health and Care Research and Wellcome King’s Research Facility, London, United Kingdom
7Hospital A Beneficência Portuguesa, São Paulo, Brazil
8Osaka University Graduate School of Medicine, Suita, Japan
9Duke University School of Medicine, Durham, NC
10UOC Oncoematologia, AULSS7 Pedemontana, Bassano del Grappa (VI), Vicenza, Italy
11University of Ulm, Ulm, Germany
12German Red Cross Blood Transfusion Service Baden-Württemberg-Hessen and University Hospital Ulm, Ulm, Germany
13Radboud University Medical Center, Nijmegen, Netherlands
14Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
15Toulouse University Hospital Center, Toulouse-Oncopole University Cancer Institute, Toulouse, France
16University Hospital RWTH Aachen, Aachen, Germany
17Medical Center Hamburg-Eppendorf, Hamburg, Germany
18ABC Medical School, Santo André, Brazil
19Novartis Pharma AG, Basel, Switzerland
20Novartis Healthcare Private Limited, Hyderabad, India
21Novartis Pharmaceuticals UK Limited, London, United Kingdom
22AORN Moscati, Avellino, Italy
23University of Naples Federico II, Naples, Italy

Gerald Illerhaus, MD1, Andrés J.M. Ferreri, MD2, Mascha Binder, MD3*, Peter Borchmann4, Justin Hasenkamp, MD5*, Stephan Stilgenbauer, MD6, Alexander Roeth, MD7, Thomas Weber8*, Gerlinde Egerer, MD9*, Thomas Ernst, MD10, Bernd Hertenstein, MD11*, Georg Lenz, MD, Prof.12, Guido Kobbe, MD13*, Uta Brunnberg, MD14*, Christian Schmidt, MD15*, Michael Kneba, MD, PhD16, Martin Dreyling, MD17, Robert Möhle, MD18, Jens Panse, MD19, Thomas Heinicke, MD20*, Sebastian Schroll, MD21*, Thomas S. Larsen, MD, PhD22*, Hans Salwender, M.D.23*, Ralph Naumann, MD24, Georg Hess, MD25*, Lorenz Thurner, MD26, Tobias Pukrop, MD27*, Ulrich Keller28*, Anne Kirsti Blystadt, MD29*, Frank P. Kroschinsky, MD, MBA30, Francesca Re, MD31*, Elisa Pulczynski, MD32*, Lorella Orsucci, MD33*, Lisa Pospiech34*, Martina Deckert35*, Maurilio Ponzoni, MD36, Julia Wendler, MD34*, Elke Valk, PhD1*, Teresa Calimeri, MD, PhD37, Benjamin Kasenda, MD PhD38*, Martin Trepel, MD39*, Heidi Fricker40*, Philipp von Gottberg41*, Elvira Burger42*, Gabriele Ihorst43*, Olga Grishina44*, Claudia Hader, MD45*, Emanuele Zucca, MD46, Jürgen Finke, MD, PhD42 and Elisabeth Schorb, MD42*

1Department of Hematology, Oncology Stem Cell Transplantation and Palliative Care, Klinikum Stuttgart, Stuttgart, Germany
2Lymphoma Unit, Department of Onco-Hematology, IRCCS San Raffaele Scientific Institute, Milan, Italy
3Martin-luther-University Halle-Wittenberg, Halle (saale), DEU
4Cologne Lymphoma Working Group, Department of Internal Medicine I, University Hospital of Cologne, Koeln, Germany
5University Medicine Göttingen, Göttingen, DEU
6Department of Internal Medicine III, Ulm University Hospital, Ulm, Germany
7Department of Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital Essen, Essen, Germany
8Department of Internal Medicine IV, Haematology and Oncology, University Hospital Halle (Saale), Martin-Luther-University Halle-Wittenberg, Halle, Germany
9Department of Internal Medicine V, University of Heidelberg, Heidelberg, Germany
10Hematology/Oncology, Jena University Hospital, Jena, Germany
11Klinikum Bremen Mitte, Bremen, Germany
12Department of Medicine A, Department of Hematology, Oncology and Pneumology, University Hospital Münster, Münster, Germany
13Department of Hematology, Oncology and Clinical Immunology, University Hospital Düsseldorf, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany
14Department of Medicine 2, Hematology and Oncology, University Hospital Frankfurt, Frankfurt, Germany
15Department of Medicine III, University Hospital, LMU Munich, Munich, Germany
16Univ. Schleswig-Holstein, Campus Kiel, Kiel, Germany
17Department of Medicine III, Klinikum Der Universitaet Muenchen-Campus Grosshadern, Munich, Germany
18Department of Hematology and Oncology, University of Tübingen, Tübingen, Germany
19Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, University Hospital RWTH Aachen, Aachen, Germany
20Department of Hematology and Oncology, University Hospital Magdeburg, Magdeburg, Sachsen-Anhalt, Germany
21Dept. of Hematology and Oncology, Städtisches Klinikum Braunschweig gGmbH, Braunschweig, Germany
22Department of Hematology, Odense University Hospital, Odense, Denmark
23Asklepios Tumorzentrum Hamburg, AK Altona and AK St. Georg, Hamburg, Germany
24Department for Internal Medicine 3, St. Marien-Krankenhaus Siegen, Siegen, Germany
25Department of Hematology, Oncology and Pneumology, University Medical Center, Johannes Gutenberg-University Mainz, Mainz, Germany
26Department of Hematology, Oncology, Rheumatology and Clinical Immunology, Saarland University Medical Center, Homburg, Germany
27Internal Medicine III, Universitätsklinikum Regensburg, Regensburg, Germany
28Department of Hematology, Oncology and Tumor Immunology, Campus Benjamin Franklin, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
29University Hospital, Oslo, Norway, Division of Cancer Medicine and Department of Oncology, Oslo, Norway
30Department of Internal Medicine I, University Hospital Carl Gustav Carus, Dresden, Germany
31Hematology and CTMO, Azienda Ospedaliera-Universitaria di Parma, Parma, Italy
32Department of Internal Medicine, Holstebro Regional Hospital, Holstebro, Denmark
33Division of Hematology, Azienda Ospedaliera e Universitaria Città della Salute e della Scienza, Torino, Italy
34Department of Hematology, Oncology and Palliative Care, Klinikum Stuttgart, Stuttgart, Germany
35University Hospital of Cologne, Cologne, DEU
36Pathology Unit, San Raffaele Scientific Institute, Milano, Italy
37Lymphoma Unit, Department of Onco-Hematology, IRCCS San Raffaele Scientific Institute, Milano, Italy
38Department of Medical Oncology, University Hospital Basel, Basel, Switzerland
39University Hospital Augsburg, Augsburg , Bay, DEU
40Department of Hematology, Oncology and Stem Cell Transplantation, University Hospital Freiburg, Freiburg im Breisgau, DEU
41Department of Neuroradiology, Klinikum Stuttgart, Stuttgart, Germany
42Department of Hematology, Oncology and Stem Cell Transplantation, Faculty of Medicine, University of Freiburg, Freiburg, Germany
43Center of clinical trials, University Medical Center Freiburg, Freiburg, DEU
44Clinical Trials Unit, University Medical Center Freiburg, Freiburg, Germany
45Clinic of Radiology, Kantonsspital St. Gallen, St. Gallen, Switzerland
46IOSI-Oncology Inst. of Southern Switzerland, Bellinzona, Switzerland

Shernan G Holtan, MD1, Mehdi Hamadani, MD2, Juan WU3*, Monzr M. AL Malki, MD4, Lyndsey Runaas, MD5*, Hany Elmariah, MD, MS6, Andrew R. Rezvani, MD7, Mahasweta Gooptu, MD8, Karilyn T. Larkin, MD9, Brian C. Shaffer, MD10, Najla H El Jurdi, MD11, Alison W. Loren, MD12, Melhem Solh, MD13, Aric C. Hall, MD14*, Amin M Alousi, MD15, Omer H Jamy, MD16, Miguel-Angel Perales, MD17, Janny M. Yao, PharmD18*, Kristy Applegate19*, Ami S. Bhatt, MD, PhD20, Leslie S. Kean, MD, PhD21, Yvonne A. Efebera, MD, MPH22, Carrie Lynn Kitko, MD23, Ran Reshef, MD, MSc24, William Clark, MD, MS25*, Nancy L. DiFronzo, PhD26*, Lori Henderson, PhD27*, Richard J. Jones, MD28, Eric Liefer29*, Michael J Martens, PhD30*, Mary M. Horowitz, MD, MS31 and Javier Bolanos-Meade, MD32

1University of Minnesota, Minneapolis, MN
2The BMT & Cellular Therapy Program, Medical College of Wisconsin, Milwaukee, WI
3The EMMES Corporation, Rockville, MD
4Department of Hematology/HCT, City of Hope, Duarte, CA
5Division of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI
6Moffitt Cancer Center, Tampa, FL
7Division of Blood and Marrow Transplantation and Cellular Therapy, Department of Medicine, Stanford University School of Medicine, Stanford, CA
8Dana-Farber Cancer Institute, Boston, MA
9Department of Internal Medicine, Division of Hematology, The Ohio State University, Columbus, OH
10Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
11Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN
12Cellular Therapy and Transplantation, Perelman Center for Advanced Medicine, Philadelphia, PA
13BMT Group of Georgia, BMT Group of Georgia, Atlanta, GA
14Division of Hematology/Oncology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI
15Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
16Division of Hematology and Oncology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL
17Adult Bone Marrow Transplant Service, Cellular Therapy Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
18Department of Pharmacy, City of Hope National Medical Center, Duarte, CA
19Emmes Corporation, Alpharetta, GA
20Departments of Genetics and Medicine, Division of Hematology, Stanford University, Palo Alto, CA
21Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA
22OhioHealth, Columbus, OH
23Division of Pediatric Hematology/Oncology, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN
24Blood and Marrow Transplantation Program, Columbia University, New York, NY
25Department Hematology/Oncology, Virginia Commonwealth University, Glen Allen, VA
26National Heart, Lung, and Blood Institute, National Institutes of Health, Division of Blood Diseases & Resources, Bethesda, MD
27NIH, Rockville, MD
28Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD
29NHLBI, Bethesda
30The Emmes Company, Rockville, MD
31Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, WI
32Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University Kimmel Cancer Center, Ellicott City, MD

Siobhan Quenby, MD PhD1*, Katie Booth2*, Louise Hiller, PhD2*, Arri Coomarasamy3*, Eva Hamulyák, MD4*, Luuk Scheres5*, Paulien G. de Jong4*, Thijs van Haaps4*, Lauren J. Ewington2*, Shreeya Tewary2*, Mariëtte Goddijn, MD PhD4* and Saskia Middeldorp, MD, PhD6,7

1Biomedical Research Unit in Reproductive Health, University of Warwick, Warwick, United Kingdom
2University of Warwick, Warwick, United Kingdom
3University of Birmingham, Birmingham, United Kingdom
4Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands
5Radboud University Medical Center, Nijmegen, Netherlands
6Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands
7Internal Medicine, Radboud University Medical Center, Nijmegen, Nijmegen, Netherlands

Jennifer R. Brown1, Barbara Eichhorst2, Peter Hillmen3, Nicole Lamanna4, Susan M. O'Brien5, Constantine S. Tam6,7*, Lugui Qiu8, Maciej Kaźmierczak9*, Wojciech Jurczak10, Keshu Zhou11*, Martin Šimkovič12,13*, Jiri Mayer14, Amanda L. Gillespie-Twardy15*, Alessandra Ferrajoli16, Peter S. Ganly17, Robert Weinkove18,19, Sebastian Grosicki20, Andrzej Mital21*, Tadeusz Robak22, Anders Österborg23,24*, Habte A. Yimer25, Tommi Salmi26*, Megan (Der Yu) Wang26*, Lina Fu26*, Jessica Li26*, Kenneth Wu26*, Aileen Cohen26* and Mazyar Shadman27,28*

1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
2Department of Internal Medicine, University of Cologne, Center for Integrated Oncology Aachen, Bonn, Cologne, Duesseldorf, Cologne, Germany
3St. James's University Hospital, Leeds, ENG, United Kingdom
4Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY
5Chao Family Comprehensive Cancer Center, University of California, Irvine, CA
6Monash University, Melbourne, VIC, Australia
7The Alfred Hospital, Melbourne, VIC, Australia
8State Key Laboratory of Experimental Hematology, National Clinical Research Center for Hematological Disorders, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China
9Department of Hematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, Poznan, Poland
10Maria Sklodowska-Curie National Research Institute of Oncology, Krakow, Poland
11Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, China
124th Department of Internal Medicine - Hematology, University Hospital, Kralove, Czech Republic
13Faculty of Medicine, Charles University, Prague, Czech Republic
14Department of Internal Medicine-Hematology and Oncology, Masaryk University and University Hospital Brno, Brno, Czech Republic
15Blue Ridge Cancer Care, Roanoke, VA
16Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
17Department of Haematology, Christchurch Hospital, Christchurch, New Zealand
18Te Rerenga Ora Blood and Cancer Centre, Te Whatu Ora Health New Zealand Capital Coast & Hutt Valley, Wellington, New Zealand
19Cancer Immunotherapy Programme, Malaghan Institute of Medical Research, Wellington, New Zealand
20Department of Hematology and Cancer Prevention, Health Sciences Faculty, Medical University of Silesia, Katowice, Poland
21Department of Hematology and Transplantology, Medical University of Gdańsk, Gdańsk, Poland
22Medical University of Lodz, Lodz, Poland
23Department of Hematology, Karolinska University Hospital, Stockholm, Sweden
24Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden
25Texas Oncology-Tyler/US Oncology Research, Tyler, TX
26BeiGene (Beijing) Co., Ltd., Beijing, China and BeiGene USA, Inc., San Mateo, CA
27Fred Hutchinson Cancer Center, Seattle, WA
28Department of Medicine, University of Washington, Seattle, WA

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