Mark R. Litzow, MD¹, Zhuoxin Sun, PhD^2*, Elisabeth Paietta, PhD³, Ryan J. Mattison, MD⁴, Hillard M Lazarus, MD⁵, Jacob M. Rowe, MB, BS⁶, Daniel A. Arber, MD⁷, Charles G. Mullighan, MBBS, MD⁸, Cheryl L Willman, MD⁹, Yanming Zhang, MD¹⁰, Matthew Wieduwilt, MD^11*, Michaela Liedtke, MD¹², Julie Bergeron, MD¹³, Keith W. Pratz, MD¹⁴, Shira Dinner, MD¹⁵, Noelle V. Frey, MD, MS¹⁶, Steven D. Gore, MD¹⁷, Bhavana Bhatnagar, DO¹⁸, Ehab L. Atallah, MD¹⁹, Geoffrey L. Uy, MD²⁰, Deepa Jeyakumar, MD²¹, Tara L. Lin, MD²², Richard F. Little, MD, MPH²³, Selina M. Luger, MD, FRCPC²⁴ and Martin S. Tallman, MD²⁵

¹Division of Hematology, Mayo Clinic, Rochester, MN
²Dana-Farber Cancer Institute, Boston, MA
³Cancer Center, Montefiore Medical Center, Bronx, NY
⁴Carbone Comprehensive Cancer Center, Madison, WI
⁵Adult Hematologic Malignancies & Stem Cell Transplant Section, University Hospitals Cleveland Medical Center, Shaker Heights, OH
⁶Department of Hematology, Shaare Zedek Medical Center, Jerusalem, Israel
⁷Department of Pathology, The University of Chicago, Chicago, IL
⁸Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN
⁹Mayo Clinic, ROCHESTER, MN
¹⁰Department of Pathology and Laboratory Medicine, Cytogenetics Laboratory, Memorial Sloan Kettering Cancer Center, New York, NY
¹¹Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK
¹²Department of Medicine, Divisions of Oncology and Hematology, Stanford University, Stanford, CA
¹³CEMTL installation Maisonneuve-Rosemont, Montreal, QC, Canada
¹⁴Department of Medicine, Hematology-Oncology Section, Hospital of the University of Pennsylvania, Philadelphia, PA
¹⁵Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL
¹⁶Abramson Cancer Center, University of Pennsylvania, Narberth, PA
¹⁷Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, MD
¹⁸Department of Hematology and Medical Oncology, West Virginia University Cancer Institute, Wheeling, WV
¹⁹Division of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI
²⁰Division of Oncology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO
²¹Division of Hematology/Oncology, UC Irvine Medical Center, Orange, CA
²²University of Kansas, Westwood, KS
²³National Cancer Institute, Washington, DC
²⁴Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA
²⁵Robert H. Lurie Comprehensive Cancer Center, Northwestern University and ECOG, Chicago, IL

Regis Peffault De Latour^1,2*, Alexander Roeth, MD³, Austin Kulasekararaj, MD, MBBS, FRCPath, MRCP^4,5,6, Phillip Scheinberg, MD⁷, Yasutaka Ueda, MD, PhD⁸, Carlos M de Castro, MD⁹, Eros Di Bona, MD^10*, Hubert Schrezenmeier, MD^11,12, Saskia MC Langemeijer, MD, PhD^13*, Wilma Barcellini, MD^14*, Suzanne Tavitian, MD^15*, Jens Panse, MD¹⁶, Philippe Schafhausen, MD^17*, Vitor AQ Mauad, MD^18*, Cecile Kerloeguen, MSc^19*, Rafael Levitch, MD^19*, Rakesh Kumar^20*, Christine Thorburn^21*, Samopriyo Maitra^20*, Marion Dahlke, MD^19* and Antonio M Risitano, MD, PhD^22,23

¹French Référence Center for Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria, Paris, France
²BMT Unit, Assistance Publique Hôpitaux de Paris, Université Paris Cité, Paris, France
³West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany
⁴King's College London, London, United Kingdom
⁵King's College Hospital NHS, London, United Kingdom
⁶National Institute for Health and Care Research and Wellcome King’s Research Facility, London, United Kingdom
⁷Hospital A Beneficência Portuguesa, São Paulo, Brazil
⁸Osaka University Graduate School of Medicine, Suita, Japan
⁹Duke University School of Medicine, Durham, NC
¹⁰UOC Oncoematologia, AULSS7 Pedemontana, Bassano del Grappa (VI), Vicenza, Italy
¹¹University of Ulm, Ulm, Germany
¹²German Red Cross Blood Transfusion Service Baden-Württemberg-Hessen and University Hospital Ulm, Ulm, Germany
¹³Radboud University Medical Center, Nijmegen, Netherlands
¹⁴Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
¹⁵Toulouse University Hospital Center, Toulouse-Oncopole University Cancer Institute, Toulouse, France
¹⁶University Hospital RWTH Aachen, Aachen, Germany
¹⁷Medical Center Hamburg-Eppendorf, Hamburg, Germany
¹⁸ABC Medical School, Santo André, Brazil
¹⁹Novartis Pharma AG, Basel, Switzerland
²⁰Novartis Healthcare Private Limited, Hyderabad, India
²¹Novartis Pharmaceuticals UK Limited, London, United Kingdom
²²AORN Moscati, Avellino, Italy
²³University of Naples Federico II, Naples, Italy

Gerald Illerhaus, MD¹, Andrés José María J.M. Ferreri, MD², Mascha Binder, MD^3*, Peter Borchmann⁴, Justin Hasenkamp, MD^5*, Stephan Stilgenbauer, MD⁶, Alexander Roeth, MD⁷, Thomas Weber^8*, Gerlinde Egerer, MD^9*, Thomas Ernst, MD¹⁰, Bernd Hertenstein, MD^11*, Georg Lenz, MD, Prof.¹², Guido Kobbe, MD^13*, Uta Brunnberg, MD^14*, Christian Schmidt, MD^15*, Michael Kneba, MD, PhD¹⁶, Martin Dreyling, MD¹⁷, Robert Möhle, MD¹⁸, Jens Panse, MD¹⁹, Thomas Heinicke, MD^20*, Sebastian Schroll, MD^21*, Thomas S. Larsen, MD, PhD^22*, Hans Salwender, M.D.^23*, Ralph Naumann, MD²⁴, Georg Hess, MD^25*, Lorenz Thurner, MD²⁶, Tobias Pukrop, MD^27*, Ulrich Keller^28*, Anne Kirsti Blystadt, MD^29*, Frank P. Kroschinsky, MD, MBA³⁰, Francesca Re, MD^31*, Elisa Pulczynski, MD^32*, Lorella Orsucci, MD^33*, Lisa Pospiech^34*, Martina Deckert^35*, Maurilio Ponzoni, MD³⁶, Julia Wendler, MD^34*, Elke Valk, PhD^1*, Teresa Calimeri, MD, PhD³⁷, Benjamin Kasenda, MD PhD^38*, Martin Trepel, MD^39*, Heidi Fricker^40*, Philipp von Gottberg^41*, Elvira Burger^42*, Gabriele Ihorst^43*, Olga Grishina^44*, Claudia Hader, MD^45*, Emanuele Zucca, MD⁴⁶, Jürgen Finke, MD, PhD⁴² and Elisabeth Schorb, MD^42*

¹Department of Hematology, Oncology Stem Cell Transplantation and Palliative Care, Klinikum Stuttgart, Stuttgart, Germany
²Lymphoma Unit, Department of Onco-Hematology, IRCCS San Raffaele Scientific Institute, Milan, Italy
³Martin-luther-University Halle-Wittenberg, Halle (saale), DEU
⁴Cologne Lymphoma Working Group, Department of Internal Medicine I, University Hospital of Cologne, Koeln, Germany
⁵University Medicine Göttingen, Göttingen, DEU
⁶Department of Internal Medicine III, Ulm University Hospital, Ulm, Germany
⁷Department of Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital Essen, Essen, Germany
⁸Department of Internal Medicine IV, Haematology and Oncology, University Hospital Halle (Saale), Martin-Luther-University Halle-Wittenberg, Halle, Germany
⁹Department of Internal Medicine V, University of Heidelberg, Heidelberg, Germany
¹⁰Hematology/Oncology, Jena University Hospital, Jena, Germany
¹¹Klinikum Bremen Mitte, Bremen, Germany
¹²Department of Medicine A, Department of Hematology, Oncology and Pneumology, University Hospital Münster, Münster, Germany
¹³Department of Hematology, Oncology and Clinical Immunology, University Hospital Düsseldorf, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany
¹⁴Department of Medicine 2, Hematology and Oncology, University Hospital Frankfurt, Frankfurt, Germany
¹⁵Department of Medicine III, University Hospital, LMU Munich, Munich, Germany
¹⁶Univ. Schleswig-Holstein, Campus Kiel, Kiel, Germany
¹⁷Department of Medicine III, Klinikum Der Universitaet Muenchen-Campus Grosshadern, Munich, Germany
¹⁸Department of Hematology and Oncology, University of Tübingen, Tübingen, Germany
¹⁹Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, University Hospital RWTH Aachen, Aachen, Germany
²⁰Department of Hematology and Oncology, University Hospital Magdeburg, Magdeburg, Sachsen-Anhalt, Germany
²¹Dept. of Hematology and Oncology, Städtisches Klinikum Braunschweig gGmbH, Braunschweig, Germany
²²Department of Hematology, Odense University Hospital, Odense, Denmark
²³Asklepios Tumorzentrum Hamburg, AK Altona and AK St. Georg, Hamburg, Germany
²⁴Department for Internal Medicine 3, St. Marien-Krankenhaus Siegen, Siegen, Germany
²⁵Department of Hematology, Oncology and Pneumology, University Medical Center, Johannes Gutenberg-University Mainz, Mainz, Germany
²⁶Department of Hematology, Oncology, Rheumatology and Clinical Immunology, Saarland University Medical Center, Homburg, Germany
²⁷Internal Medicine III, Universitätsklinikum Regensburg, Regensburg, Germany
²⁸Department of Hematology, Oncology and Tumor Immunology, Campus Benjamin Franklin, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
²⁹University Hospital, Oslo, Norway, Division of Cancer Medicine and Department of Oncology, Oslo, Norway
³⁰Department of Internal Medicine I, University Hospital Carl Gustav Carus, Dresden, Germany
³¹Hematology and CTMO, Azienda Ospedaliera-Universitaria di Parma, Parma, Italy
³²Department of Internal Medicine, Holstebro Regional Hospital, Holstebro, Denmark
³³Division of Hematology, Azienda Ospedaliera e Universitaria Città della Salute e della Scienza, Torino, Italy
³⁴Department of Hematology, Oncology and Palliative Care, Klinikum Stuttgart, Stuttgart, Germany
³⁵University Hospital of Cologne, Cologne, DEU
³⁶Pathology Unit, San Raffaele Scientific Institute, Milano, Italy
³⁷Lymphoma Unit, Department of Onco-Hematology, IRCCS San Raffaele Scientific Institute, Milano, Italy
³⁸Department of Medical Oncology, University Hospital Basel, Basel, Switzerland
³⁹University Hospital Augsburg, Augsburg , Bay, DEU
⁴⁰Department of Hematology, Oncology and Stem Cell Transplantation, University Hospital Freiburg, Freiburg im Breisgau, DEU
⁴¹Department of Neuroradiology, Klinikum Stuttgart, Stuttgart, Germany
⁴²Department of Hematology, Oncology and Stem Cell Transplantation, Faculty of Medicine, University of Freiburg, Freiburg, Germany
⁴³Center of clinical trials, University Medical Center Freiburg, Freiburg, DEU
⁴⁴Clinical Trials Unit, University Medical Center Freiburg, Freiburg, Germany
⁴⁵Clinic of Radiology, Kantonsspital St. Gallen, St. Gallen, Switzerland
⁴⁶IOSI-Oncology Inst. of Southern Switzerland, Bellinzona, Switzerland

Shernan G Holtan, MD¹, Mehdi Hamadani, MD², Juan WU^3*, Monzr M. AL Malki, MD⁴, Lyndsey Runaas, MD^5*, Hany Elmariah, MD, MS⁶, Andrew R. Rezvani, MD⁷, Mahasweta Gooptu, MD⁸, Karilyn T. Larkin, MD⁹, Brian C. Shaffer, MD¹⁰, Najla H El Jurdi, MD¹¹, Alison W. Loren, MD¹², Melhem Solh, MD¹³, Aric C. Hall, MD^14*, Amin M Alousi, MD¹⁵, Omer H Jamy, MD¹⁶, Miguel-Angel Perales, MD¹⁷, Janny M. Yao, PharmD^18*, Kristy Applegate^19*, Ami S. Bhatt, MD, PhD²⁰, Leslie S. Kean, MD, PhD²¹, Yvonne A. Efebera, MD, MPH²², Carrie Lynn Kitko, MD²³, Ran Reshef, MD, MSc²⁴, William Clark, MD, MS^25*, Nancy L. DiFronzo, PhD^26*, Lori Henderson, PhD^27*, Richard J. Jones, MD²⁸, Eric Liefer^29*, Michael J Martens, PhD^30*, Mary M. Horowitz, MD³¹ and Javier Bolanos-Meade, MD³²

¹University of Minnesota, Minneapolis, MN
²The BMT & Cellular Therapy Program, Medical College of Wisconsin, Milwaukee, WI
³The EMMES Corporation, Rockville, MD
⁴Department of Hematology/HCT, City of Hope, Duarte, CA
⁵Division of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI
⁶Moffitt Cancer Center, Tampa, FL
⁷Division of Blood and Marrow Transplantation and Cellular Therapy, Department of Medicine, Stanford University School of Medicine, Stanford, CA
⁸Dana-Farber Cancer Institute, Boston, MA
⁹Department of Internal Medicine, Division of Hematology, The Ohio State University, Columbus, OH
¹⁰Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
¹¹Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN
¹²Cellular Therapy and Transplantation, Perelman Center for Advanced Medicine, Philadelphia, PA
¹³BMT Group of Georgia, BMT Group of Georgia, Atlanta, GA
¹⁴Division of Hematology/Oncology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI
¹⁵Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
¹⁶Division of Hematology and Oncology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL
¹⁷Adult Bone Marrow Transplant Service, Cellular Therapy Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
¹⁸Department of Pharmacy, City of Hope National Medical Center, Duarte, CA
¹⁹Emmes Corporation, Alpharetta, GA
²⁰Departments of Genetics and Medicine, Division of Hematology, Stanford University, Palo Alto, CA
²¹Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA
²²OhioHealth, Columbus, OH
²³Division of Pediatric Hematology/Oncology, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN
²⁴Blood and Marrow Transplantation Program, Columbia University, New York, NY
²⁵Department Hematology/Oncology, Virginia Commonwealth University, Glen Allen, VA
²⁶National Heart, Lung, and Blood Institute, National Institutes of Health, Division of Blood Diseases & Resources, Bethesda, MD
²⁷NIH, Rockville, MD
²⁸Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD
²⁹NHLBI, Bethesda
³⁰The Emmes Company, Rockville, MD
³¹Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, WI
³²Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University Kimmel Cancer Center, Ellicott City, MD

Siobhan Quenby, MD PhD^1*, Katie Booth^2*, Louise Hiller, PhD^2*, Arri Coomarasamy^3*, Eva Hamulyák, MD^4*, Luuk Scheres^5*, Paulien G. de Jong^4*, Thijs van Haaps^4*, Lauren J. Ewington^2*, Shreeya Tewary^2*, Mariëtte Goddijn, MD PhD^4* and Saskia Middeldorp, MD, PhD⁶

¹Biomedical Research Unit in Reproductive Health, University of Warwick, Warwick, United Kingdom
²University of Warwick, Warwick, United Kingdom
³University of Birmingham, Birmingham, United Kingdom
⁴Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands
⁵Radboud University Medical Center, Nijmegen, Netherlands
⁶Internal Medicine, Radboud University Medical Center, Nijmegen, Nijmegen, Netherlands

Jennifer R. Brown¹, Barbara Eichhorst², Peter Hillmen³, Nicole Lamanna, MD⁴, Susan M. O'Brien⁵, Constantine S. Tam^6,7*, Lugui Qiu⁸, Maciej Kaźmierczak^9*, Wojciech Jurczak¹⁰, Keshu Zhou^11*, Martin Šimkovič^12,13*, Jiri Mayer¹⁴, Amanda L. Gillespie-Twardy^15*, Alessandra Ferrajoli¹⁶, Peter S. Ganly¹⁷, Robert Weinkove^18,19, Sebastian Grosicki²⁰, Andrzej Mital^21*, Tadeusz Robak²², Anders Österborg^23,24*, Habte A. Yimer²⁵, Tommi Salmi^26*, Megan (Der Yu) Wang^26*, Lina Fu^26*, Jessica Li^26*, Kenneth Wu^26*, Aileen Cohen^26* and Mazyar Shadman^27,28*

¹Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
²Department of Internal Medicine, University of Cologne, Center for Integrated Oncology Aachen, Bonn, Cologne, Duesseldorf, Cologne, Germany
³St. James's University Hospital, Leeds, ENG, United Kingdom
⁴Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY
⁵Chao Family Comprehensive Cancer Center, University of California, Irvine, CA
⁶Monash University, Melbourne, VIC, Australia
⁷The Alfred Hospital, Melbourne, VIC, Australia
⁸State Key Laboratory of Experimental Hematology, National Clinical Research Center for Hematological Disorders, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China
⁹Department of Hematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, Poznan, Poland
¹⁰Maria Sklodowska-Curie National Research Institute of Oncology, Krakow, Poland
¹¹Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, China
¹²4th Department of Internal Medicine - Hematology, University Hospital, Kralove, Czech Republic
¹³Faculty of Medicine, Charles University, Prague, Czech Republic
¹⁴Department of Internal Medicine-Hematology and Oncology, Masaryk University and University Hospital Brno, Brno, Czech Republic
¹⁵Blue Ridge Cancer Care, Roanoke, VA
¹⁶Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
¹⁷Department of Haematology, Christchurch Hospital, Christchurch, New Zealand
¹⁸Te Rerenga Ora Blood and Cancer Centre, Te Whatu Ora Health New Zealand Capital Coast & Hutt Valley, Wellington, New Zealand
¹⁹Cancer Immunotherapy Programme, Malaghan Institute of Medical Research, Wellington, New Zealand
²⁰Department of Hematology and Cancer Prevention, Health Sciences Faculty, Medical University of Silesia, Katowice, Poland
²¹Department of Hematology and Transplantology, Medical University of Gdańsk, Gdańsk, Poland
²²Medical University of Lodz, Lodz, Poland
²³Department of Hematology, Karolinska University Hospital, Stockholm, Sweden
²⁴Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden
²⁵Texas Oncology-Tyler/US Oncology Research, Tyler, TX
²⁶BeiGene (Beijing) Co., Ltd., Beijing, China and BeiGene USA, Inc., San Mateo, CA
²⁷Fred Hutchinson Cancer Center, Seattle, WA
²⁸Department of Medicine, University of Washington, Seattle, WA