Daisuke Ikeda^1*, Toshiki Terao, MD^2*, Ami Fukumoto, MD^3*, Ayumi Kuzume, MD^4*, Yuya Kamura, MD^5*, Rikako Tabata, MD^4*, Takafumi Tsushima, MD^5*, Daisuke Miura, MD^2*, Kentaro Narita, MD^6*, Masami Takeuchi, MD^5*, Takeshi Yamashita, MD^7*, Hiroyuki Takamatsu, MD, PhD⁸ and Kosei Matsue, MD, PhD⁹

¹Division of Hematology/Oncology, Kameda Medical Center, Kamogawa-Shi, CHI, Japan
²Division of Hematology/Oncology, Department of Medicine, Kameda Medical Center, Kamogawa, Japan
³Division of Hematology/Oncology, Kameda Medical Center, Chiba, JPN
⁴Division of Hematology/Oncology, Kameda Medical Centor, Kamogawa, Japan
⁵Division of Hematology/Oncology, Kameda Medical Center, Kamogawa, Japan
⁶Division of Hematology/Oncology, Department of Medicine, Kameda Medical Center, Kamogawa, CHI, Japan
⁷Division of Internal Medicine, Keiju Kanazawa Hospital, Kanazawa, Japan
⁸Department of Hematology, Kanazawa University, Kanazawa, Japan
⁹Department of Hematology/Oncology, Kameda Medical Center, Kamogawa, Japan

Cèlia Dobaño-López, MSc^1,2*, Juan G Valero, PhD^1,2*, Ferran Araujo-Ayala^1,2*, Ferran Nadeu, PhD^1,2*, Fabien Gava, PhD^3*, Carla Faria, PhD^3*, Marine Norlund, PhD^4*, Renaud Morin, PhD^4*, Pascale Bernes-Lasserre^4*, Neus Serrat, MD, PhD^2*, Heribert Playa-Albinyana, MSc^1,2*, Andrea Rivero, MD^5*, Pablo Mozas, MD, PhD^5*, Elías Campo, PhD MD^1,2,6,7, Jean-Michel Lagarde, PhD^4*, Armando López-Guillermo, MD, PhD^1,2,5,7*, Dolors Colomer, PhD^1,2,6,7*, Christine Bezombes, PhD^3* and Patricia Pérez-Galán, PhD^1,2*

¹Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain
²Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
³Centre de Recherches en Cancérologie de Toulouse, INSERM, Toulouse, France
⁴IMACTIV-3D, Toulouse, France
⁵Hematology Department, Hospital Clínic of Barcelona, Barcelona, Spain
⁶Hematopathology Section, Pathology Department, Hospital Clinic, Barcelona, Spain
⁷University of Barcelona, Barcelona, Spain

Huang-Chang Liang^*, Richa Kapoor, PhD^*, Ozlem Onder, PhD^*, Kevin Dennis^*, Megan S. Lim, MD, PhD and Kojo S. J. Elenitoba-Johnson, MD

Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA

PK Epling-Burnette, PharmD, PhD^1*, Durga B Dandamudi, PhD^1*, Iwona M Konieczna, PhD^1*, Kelly M Calabrese^1*, Monica Wielgos-Bonvallet, PhD^2*, Christiaan Kweekel, MSc^3*, Elke Gresnigt - van den Heuvel^3*, Apurvasena Parikh, PhD^4*, Tommy Li, PhD^5*, Christopher W Chiu, PhD^5*, Adam Chervin, PhD^1*, Edward B Reilly, PhD^1* and Edith Szafer-Glusman, PhD^1*

¹AbbVie Inc, North Chicago, IL
²Translational Research and Precision Medicine Operations, Genmab, Princeton, NJ
³Genmab, Utrecht, Netherlands
⁴AbbVie, South San Francisco, CA
⁵Genmab, Princeton, NJ

Beatriz Wills, MD¹, Nivetha Ganesan, MPH^2*, Gunjan L. Shah, MD^3*, Phillip Wong, PhD^4*, Kimon V. Argyropoulos, MD^2*, Filiz Sen, MD^5*, Ahmet Dogan, MD, PhD⁶, David J. Straus, MD², Ariela Noy, MD², Anita Kumar, MD², Heiko Schoder, MD, MBA^7*, Laure Michaud, MD^7*, Maria Lia Palomba², Lorenzo Falchi, MD⁸, Oscar B Lahoud, MD⁹, Paul A. Hamlin, MD², Joachim Yahalom, MD¹⁰, William T. Johnson, DO², Andrew D. Zelenetz, MD, PhD², Andrew M. Intlekofer, MD, DPhil², Colette Owens, MD², Connie Lee Batlevi, MD, PhD¹¹, Audrey Hamilton, MD^2*, Philip C Caron, MD, PhD², Steven M. Horwitz, MD², Natasha Galasso, MSW^2*, Helen Hancock, ANP^2*, Theresa Davey, MMSc, PA-C^12*, Alayna Santarosa, MPH^12*, Leslie Perez, RN^12*, Charisse Capadona, MS^4*, Brittney Munayirji^4*, Matthew J. Matasar, MD, MS¹³, Georgios Pongas, MD¹⁴, Ellie Casper, MS^4*, Gilles Salles, MD, PhD², Craig H. Moskowitz, MD¹⁴, Santosha Vardhana, MD, PhD² and Alison J. Moskowitz, MD²

¹Memorial Sloan Kettering Cancer Center, New York
²Department of Medicine, Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY
³Department of Medicine, Adult Bone Marrow Transplant Service, Cellular Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY
⁴Memorial Sloan Kettering Cancer Center, NYC
⁵Hematopathology Service, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY
⁶Department of Pathology and Laboratory Medicine, Hematopathology Service, Memorial Sloan Kettering Cancer Center, New York, NY
⁷Department of Radiology, Molecular Imaging and Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY
⁸Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY
⁹Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
¹⁰Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY
¹¹Lymphoma Service, Cellular Therapy Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, NEW YORK, NY
¹²Memorial Sloan Kettering Cancer Center, New York, NY
¹³215 West 90th St, 14E, Memorial Sloan Kettering Cancer Center, New York, NY
¹⁴Sylvester Comprehensive Cancer Center, University of Miami Health System, Miami, FL

Ying Yu^1*, Wenjie Xiong^2*, Zanzan Wang^3*, Yuting Yan^2*, Jiawen Chen^2*, Yanshan Huang^2*, Xinxin Cao^4*, Zhongxing Jiang^5*, Huihan Wang^6*, Zhen Cai, PhD, MD^7*, Juan Du^8*, Chunyan Sun, MD^9*, Ting Niu¹⁰, Guangzhong Yang^11*, Hua Xue^12*, Bingzong Li, MD, PhD¹³, Honghui Huang^14*, Zhenling Li^15*, Qinhua Liu^16*, Fei Li^17*, Ou Bai, MD/PhD^18*, Min Mao^19*, Rong Fu, MD^20*, Ling Wang^21*, Chunrui Li, MD, PhD²², Xiaoxia Chu^23*, Lihong Liu^24*, Yujun Dong^25*, Luqun Wang^26*, Jun Luo^27*, Yongqiang Wei^28*, Lugui Qiu², Jian Li, MD²⁹ and ShuHua Yi^2*

¹State Key Laboratory of Experimental Hematology, National Clinical Research Cent, Tianjin, China
²State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical Colleg, Tianjin, China
³Department of Hematology, Ningbo First Hospital, Zhejiang, China
⁴Department of Hematology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China
⁵The First Affiliated Hospital of Zhengzhou University, Henan, China
⁶Shengjing Hospital of China Medical University, Liaoning, China
⁷Bone Marrow Transplantation Center, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
⁸Department of Hematology, Myeloma & Lymphoma Center, Shanghai Changzheng Hospital, The Second Military Medical University, Shanghai, China
⁹Union Hospital,Tongji Medical College,Huazhong University of Science and Technology, Wuhan, China
¹⁰West China Hospital of Sichuan University, Chengdu, Sichuan, China
¹¹Department of Hematology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
¹²The Second Hospital of Hebei Medical University, Hebei, China
¹³Department of Hematology, The second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
¹⁴Department of Hematology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
¹⁵Department of Hematology, China-Japan Friendship Hospital, Beijing, China
¹⁶Department of Hematology, The First Affiliated Hospital of Anhui Medical University, Anhui, China
¹⁷The First Affiliated Hospital of Nanchang University, Nanchang, China
¹⁸Department of Hematology, The First Hospital of Jilin University, Changchun, China
¹⁹Department of Hematology, Xinjiang Uiger Municipal People’s Hospital, Xinjiang, China
²⁰Department of Hematology, Tianjin Medical University General Hospital, Tianjin, China
²¹Qingdao Central Hospital, Shandong, China
²²Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
²³The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Shandong, China
²⁴Department of Hematology, The Fourth Hospital of Hebei Medical University, Hebei, China
²⁵Department of Hematology, Peking University First Hospital, Beijing, China
²⁶Department of Hematology, Qilu Hospital of Shandong University, Shandong, Shandong, China
²⁷Department of Hematology, The First Affiliated Hospital of Guangxi Medical University, Guangxi, China
²⁸Department of Hematology, Nanfang Hospital, Southern Medical University, Guangdong, China
²⁹Department of Hematology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

Alexander Biedermann^1*, Doris Mangelberger-Eberl^2*, Dimitrios Mougiakakos, MD³, Maike Büttner-Herold^4*, Cindy Flamann^5*, Christian Kellner^6*, Sarah Altmeyer^7*, Jörg Bittenbring^8*, Christian Augsberger^2*, Maria Patra-Kneuer, Ph.D.^2*, Karin Landgraf^2*, Kristina Ilieva-Babinski^2*, Stefan Haskamp^1*, Fabian Beier, MD^9*, Simon Voelkl, PhD^10*, Christian Pallasch^11*, Benedikt Jacobs, MD^12*, Stefan Steidl, Ph.D.^2*, Christina Heitmüller, Ph.D.^2*, Andreas Mackensen, MD^13* and Heiko Bruns, PhD^14*

¹University Hospital Erlangen, Erlangen, Germany
²MorphoSys AG, Planegg, Germany
³Otto von Guericke University Magdeburg, Magdeburg, Germany
⁴Department of Nephropathology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
⁵Dept. of Internal Medicine 5 – Hematology/Oncology, University of Erlangen, Erlangen, Germany
⁶Department of Transfusion Medicine, Cell Therapeutics and Hemostaseology, University Hospital, LMU Munich, Munich, Germany
⁷Saarland University Hospital, Homburg, DEU
⁸Department of Hematology, Oncology, Clinical Immunology, Rheumatology, Medical School, University of Saarland, Homburg, Germany
⁹Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Medical Faculty, RWTH Aachen University, Aachen, NRW, Germany
¹⁰Department of Internal Medicine 5 - Hematology/Oncology, University Hospital of Erlangen, Erlangen, Germany
¹¹University Hospital of Cologne, Cologne, Germany
¹²Department of Hematology and Oncology, University Hospital Erlangen, Erlangen, Germany
¹³Dept. of Internal Medicine 5 - Hematology/Oncology, University Hospital of Erlangen, Erlangen, Germany
¹⁴Dept. of Internal Medicine 5 - Hematology/Oncology, University Hospital Erlangen, Erlangen, Germany

Marina Gerousi^1*, Anastasia Iatrou^1,2*, Antonios Mingos^1,2*, Nikolaos Pechlivanis^1,3*, Stavroula Ntoufa^1*, Maria Gounari^1*, Nikos Papakonstantinou^1*, Georgios Karakatsoulis^1,4*, Eleni Kotroni^1*, Ioannis Sarrigeorgiou^5*, Zadie Davis^6*, Peggy Lymberi^5*, David Oscier⁶, Ioanna Sakellari^7*, Alexandra Traverse-Glehen^8*, Niki Stavroyianni^9*, Fotis Psomopoulos^1*, Marta Muzio^10*, Paolo Ghia, MD, PhD¹¹, Anastasia Chatzidimitriou^1,12* and Kostas Stamatopoulos, MD^1,12

¹Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece
²Department of Molecular Biology and Genetics, Democritus University of Thrace, Alexandroupolis, Greece
³Department of Genetics, Development and Molecular Biology, Faculty of Biology, Aristotle University of Thessaloniki, Thessaloniki, Greece
⁴Department of Mathematics, School of Sciences, University of Ioannina, Ioannina, Greece
⁵Immunology Laboratory, Immunology Department, Hellenic Pasteur Institute, Athens, Greece
⁶Royal Bournemouth Hospital, Bournemouth, United Kingdom
⁷Hematology Department and HCT Unit, George Papanikolaou General Hospital, Thessaloniki, Greece
⁸Department of Pathology, Centre Hospitalier Lyon Sud and Université Claude Bernard Lyon-1, Pierre- Bénite, France
⁹Hematology Department and HCT Unit, G. Papanicolaou Hospital, Thessaloniki, Greece
¹⁰Cell Signaling Unit, Division of Experimental Oncology, San Raffaele Hospital Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Milan, Italy
¹¹Università Vita-Salute San Raffaele and Istituto di Ricovero e Cura a Carattere Scientifico Ospedale San Raffaele, Milan, Italy
¹²Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden

Harpreet Mandhair, MSc^1,2*, Ramin Radpour, PhD^1,2*, Andrew Davies^3*, Mario P. Tschan, PhD⁴ and Urban Novak^1,2*

¹Department of Medical Oncology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
²University of Bern, Department of BioMedical Research, Bern, Switzerland
³Southampton Cancer Research UK (CRUK) Centre/CRUK Experimental Cancer Medicines Centre UK/CRUK Southampton Clinical Trials Unit, University of Southampton, Southampton, United Kingdom
⁴Division of Experimental Pathology, Institute of Pathology, University of Bern, Bern, Switzerland

Vera de Jonge^1*, Carolien Duetz, MD^2*, Wassilis S.C. Bruins, MD, MSc^3*, Erik D. van Werkhoven, MSc^4*, Marcel Nijland, MD, PhD^5*, Marjolein W.M. Van Der Poel⁶, Koen de Heer, MD, PhD^7*, Clara P.W. Klerk, MD^8*, Yorick Sandberg, MD^9*, Rob Fijnheer^10*, Pim Mutseaers, MD^11*, Djamila E. Issa, MD, PhD^12*, Lara H. Böhmer, MD^13*, Roel J.W. Van Kampen, MD, PhD¹⁴, Otto J. Visser, MD¹⁵, Daphne de Jong, MD, PhD^16*, Josée M. Zijlstra, MD PhD¹, Tuna Mutis, MD, PhD^17* and Martine E.D. Chamuleau, MD, PhD¹

¹Department of Hematology, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam, Netherlands
²Department of Hematology, Cancer Center Amsterdam, Amsterdam UMC, location Vrije Universiteit Amsterdam, Amsterdam, NV, Netherlands
³Department of Hematology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, Netherlands
⁴Hovon data center, department of Hematology, Erasmus MC Cancer institute, Rotterdam, Netherlands
⁵Department of Hematology, University Medical Center Groningen and University of Groningen, Groningen, Netherlands
⁶Department of Hematology, Maastricht University Medical Center, Maastricht, Netherlands
⁷Department of Hematology, Amsterdam UMC, Amsterdam, Netherlands
⁸Dijklanderziekenhuis, Hoorn, Netherlands
⁹Department of Internal Medicine, Maasstad Hospital, Rotterdam, Netherlands
¹⁰Meander Medical Center, Department of Internal Medicine, Amersfoort, Netherlands
¹¹Department of Hematology, Erasmus MC Cancer Center, Rotterdam, Netherlands
¹²Department of Hematology, Jeroen Bosch Hospital, Den Bosch, Netherlands
¹³Department of Hematology, Haga Teaching Hospital, The Hague, Netherlands
¹⁴Zuyderland Medical Center, Sittard-Geleen, NLD
¹⁵Department of Hematology, Isala Hospital, Zwolle, Netherlands
¹⁶Department of Pathology, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam, Netherlands
¹⁷Cancer Biology and Immunology, Cancer Center Amsterdam, Amsterdam, Netherlands

Charline Fuseau, MD^1,2*, Mathieu Baldacini, MD^2*, Alina Nicolae, MD-PHD^1,3*, Laurent Miguet, PhD^1,4*, Laurent Mauvieux, MD, PhD^1,4, Laurent Vallat, MD, PhD^1,4*, Claire Domon-Dell, PhD^1*, Manuela Tavian, PhD^1*, Jean-Noel Freund, PhD^1*, Sarah Cianferani, PhD^5,6*, Christine Schaeffer-Reiss, PhD^5,6*, Luc-Matthieu Fornecker, MD, PhD^1,2* and Delphine C. M. Rolland, PharmD^1,4

¹Interface de Recherche Fondamentale et Appliquée en Cancérologie (IRFAC), INSERM UMR-1113, Université de Strasbourg, Strasbourg, France
²Institut de Cancérologie Strasbourg Europe, Strasbourg, France
³Département de pathologie, Hôpitaux Universitaire de Strasbourg, Strasbourg, France
⁴Laboratoire d’hématologie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France
⁵Laboratoire de Spectrométrie de Masse BioOrganique, Institut Pluridisciplinaire Hubert Curien (IPHC), CNRS UMR-7178, Université de Strasbourg, Strasbourg, France
⁶Infrastructure Nationale de Protéomique ProFi – FR2048 CNRS, Strasbourg, France

Xiaomin Chen^1,2*, Tiange Lu^1,2*, Yiqing Cai^1,2*, Mengfei Ding^1*, Zhuoya Yu^1*, Xiangxiang Zhou, PhD^2* and Xin Wang^1,2

¹Department of Hematology, Shandong Provincial Hospital, Shandong University, Jinan, Shandong, China
²Department of Hematology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China

Gensuke Takayama, PhD^1*, Yoshiyuki Hizukuri, Ph.D.^2*, Tomoyuki Fujioka, Ph.D.^2*, Kazuyuki Hashimoto, Ph.D.^2*, Kazumi Ito, D.V.M., Ph.D.^2*, Hironori Yamada, MSc^3*, Makoto Yamagishi, PhD^4*, Makoto Nakashima, Ph.D.^4*, Yutaka Suzuki, Ph.D.^5*, Yasuhito Nannya, M.D., Ph.D.⁶, Kaoru Uchimaru, M.D., Ph.D.^4,6* and Shinji Tsutsumi, Ph.D.^2*

¹Translational Science I, Daiichi Sankyo Co., Ltd., Shinagawa-Ku, Japan
²Translational Science I, Daiichi Sankyo Co., Ltd., Tokyo, Japan
³Clinical Development Department II, Daiichi Sankyo Co., Ltd., Tokyo, Japan
⁴Laboratory of Tumor Cell Biology, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan
⁵Laboratory of Systems Genomics, Department of Computational Biology and Medical Sciences, The University of Tokyo, Tokyo, Japan
⁶Department of Hematology/Oncology, IMSUT Hospital, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan

Jerzy Dyczkowski, PhD^1*, Alex F. Herrera, MD², Carmelo Carlo-Stella, MD, PhD³, Pier Luigi Zinzani, MD, PhD⁴, Marie Toukam, PhD^5*, Hans G. Cruz, PhD¹, Karin Havenith, PhD^6*, Joseph Boni, PhD^5*, Jens Wuerthner, MD, PhD¹ and Serafino Pantano, PhD^1*

¹ADC Therapeutics SA, Épalinges, Switzerland
²Department of Hematology and Hematopoietic Cell Transplantation, City of Hope Comprehensive Cancer Center, Duarte, CA
³Department of Oncology and Hematology, Humanitas University and IRCCS Humanitas Research Hospital, Milan, Italy
⁴Institute of Hematology “Seràgnoli” University of Bologna, Bologna, Italy
⁵ADC Therapeutics America, Inc., Murray Hill, NJ
⁶ADC Therapeutics (UK) Ltd, London, United Kingdom

Ava J Boutilier^1*, Anna D Metzler^1*, Cameron E Banks^2*, Sherine F Elsawa, PhD³, Stephan Josef Matissek^3* and Katja Koeppen^4*

¹Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH
²University of New Hampshire - Molecular, Cellular, and Biomedical Sciences, Durham, NH
³Molecular, Cellular and Biomedical Sciences, University of New Hampshire, Durham, NH
⁴Dartmouth College, Hanover

Richa Kapoor, PhD^1*, Kaiyu Ma, PhD^2*, Faith Key^1*, Huang-Chang Liang^3*, Xiao Zhang^2*, Megan S. Lim, MD, PhD² and Kojo S. J. Elenitoba-Johnson, MD²

¹University of Pennsylvania, PHILADELPHIA, PA
²Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA
³University of Pennsylvania, Philadelphia, PA

Maria Carmela Vegliante, PhD^1*, Grazia Gargano, MSc^1*, Flavia Esposito, PhD^2*, Giuseppina Opinto, PhD^1*, Gian Maria Zaccaria, PhD^1*, Susanna Anita Pappagallo^1*, Paolo Mondelli, MSc^1*, Giacomo Loseto, MD^1*, Anna Scattone, MD^3*, Elena Sabattini, MD^4*, Claudio Agostinelli, MD^4*, Valentina Tabanelli, PhD^5*, Luca Nassi, MD^6*, Attilio Guarini, MD^1*, Stefano A Pileri, MD⁵ and Sabino Ciavarella, PhD^1*

¹Hematology and Cell Therapy Unit, IRCCS Istituto Tumori 'Giovanni Paolo II', Bari, Italy
²Department of Mathematics, University of Bari Aldo Moro, Bari, Italy
³Pathology Department, IRCCS Istituto Tumori 'Giovanni Paolo II', Bari, Italy
⁴Haematopathology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna and Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy
⁵Division of Diagnostic Haematopathology, IEO Istituto Europeo di Oncologia IRCCS, Milano, Italy
⁶Department of Hematology, Careggi Hospital and University of Florence, Florence, Italy

Hyokyoung G Hong, PhD^1*, Mateus H Gouveia^2*, Martin Ogwang^3*, Patrick Kerchan^4*, Steven Reynolds^5*, Constance N Tenge^6*, Pamela A Were^7*, Robert T Kuremu^6*, Walter N Wekesa^6*, Nestory Masalu^8*, Esther Kawira^9*, Tobias Kinyera^10*, Xunde Wang, PhD^11*, Jiefu Zhou^12*, Isaac Otim^13*, Ismail D Legason^13*, Hadijah Nabalende^10*, Herry Dhudha^9*, Mediatrix Mumia^7*, Francine G Baker^14*, Temi Okusolubo^11*, Leona W Ayers^15*, Kishor Bhatia, PhD^16*, James J Goedert^14*, Joshua G Woo^14*, Nathan Cole^17*, Wen Luo^17,18*, Belynda Hicks^19,20*, Adebowale A Adeyemo^21*, Ludmila Prokunina-Olsson, PhD^22*, Daniel N. Shriner, PhD^23*, Charles N Rotimi^21*, George Chagaluka^24*, W Thomas Johnston^25*, Nora Mutalima^25*, Eric Borgstein^24*, George N Liomba^24*, Steve Kamiza^24*, Nyengo Mkandawire^24*, Collins Mitambo^26*, Collins Mitambo^26*, Elizabeth Molyneux^27*, Robert Newton^28*, Michelle Manning^17*, Joseph F Fraumeni Jr.^14*, Ruth M Pfeiffer^14*, Amy Hutchinson^29*, Meredith Yeager, PhD^29*, Swee Lay Thein, DSc, FRCP, FRCPath, MBBS, MRCPath, MRCP³⁰, Stephen J. Chanock, MD^31* and Sam M. Mbulaiteye, MBBChir, MPhil^32*

¹Division of Cancer Epidemiology & Genetics, National Cancer Institute, Rockville, MD
²National Institutes of Health, Bethesda, MD
³EMBLEM study, ST. MARY'S HOSPITAL LACOR, Gulu, UGA
⁴African Field Epidemiology Network, Kampala, Uganda
⁵NIAID/NIH, Dulles, VA
⁶Moi University College of Health Sciences, Eldoret, Kenya
⁷Academic Model Providing Access To Healthcare (AMPATH), Eldoret, Kenya
⁸Bugando Medical Center, Mwanza, Tanzania, United Republic of
⁹Shirati Health, Education, and Development Foundation, Shirati, Tanzania, United Republic of
¹⁰ST. MARY'S HOSPITAL LACOR, Gulu, UGA
¹¹Sickle Cell Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
¹²Department of Statistics and Probability, Michigan State University, Michigan, MI
¹³St. Mary’s Hospital, Lacor, Gulu, Uganda
¹⁴National Cancer Institute, Rockville, MD
¹⁵The Ohio State University, Columbus, OH
¹⁶Cancer Genetics Inc, Rutherford, NJ
¹⁷Frederick National Laboratory for Cancer Research, Frederick, MD
¹⁸Division of Cancer Epidemiology and Genetics,, National Cancer Institute, Rockville, MD
¹⁹Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD
²⁰Leidos Biomedical Research, Inc. Frederick National Laboratory for Cancer Research, Frederick, MD
²¹Center for Research on Genomics & Global Health, NHGRI, Bethesda, MD
²²Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD
²³Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD
²⁴University of Malawi, Blantyre, Malawi
²⁵University of York, York, United Kingdom
²⁶Research Department, Ministry of Health, Lilongwe, Malawi
²⁷Queen Elizabeth Central Hospital, Blantyre, MWI
²⁸University of York, York, GBR
²⁹Cancer Genomics Research Laboratory, Frederick National Laboratory, Frederick, MD
³⁰Sickle Cell Branch, National Institutes of Health, National Heart, Lung & Blood Institute, Bethesda, MD
³¹Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD
³²Division of Cancer Epidemiology and Genetics, National Cancer Institute, Silver Spring, MD

Antonio Frolli, MD^1*, Silvia Varvello, MD^2*, Annalisa Balbo Mussetto, MD^3*, Daniela Gottardi, MD^2*, Martina Bullo, MD^1*, Silvia Marini, PhD^1*, Giuseppe Saglio, MD¹, Stefano Cirillo, MD^3*, Daniela Cilloni, MD^4* and Guido Eugenio Parvis, MD^2*

¹Department of Clinical and Biological Sciences, University of Turin, Turin, Italy
²Division of Hematology, Mauriziano Hospital, Turin, Italy
³Division of Radiology, AO Ordine Mauriziano, Turin, Italy
⁴Department of Clinical and Biological Sciences, University of Turin, Orbassano, Italy