Sarah Haebe, MD^1*, Tanaya Shree, MD, PhD¹, Grady Day^1*, Debra K. Czerwinski¹, Anuja Sathe, MD, PhD^1*, Susan M. Grimes, BSc^2*, Steven R. Long, MD^3,4*, Brock Martin, MD^4*, Michael G. Ozawa, MD, PhD^4*, Hanlee P. Ji, MD^1,2* and Ronald Levy, MD¹

¹Department of Medicine, Division of Oncology, Stanford University School of Medicine, Stanford, CA
²Stanford Genome Technology Center, Stanford University, Stanford, CA
³Department of Pathology, University of California San Francisco, San Francisco, CA
⁴Department of Pathology, Stanford University School of Medicine, Stanford, CA

Julia Driessen, BSc^1*, Wouter J. Plattel, MD PhD^2*, Lydia Visser^3*, Anke Van Den Berg, PhD³, Josée M. Zijlstra, MD PhD⁴, Sanne Tonino^5*, Gerben JC Zwezerijnen, MD^6*, Ronald Boellaard, PhD^6*, Marie José Kersten, MD, PhD¹ and Arjan Diepstra, M.D., Ph.D.³

¹Department of Hematology, Amsterdam UMC, Location AMC, University of Amsterdam, LYMMCARE, Cancer Center Amsterdam, Amsterdam, Netherlands
²Department of Hematology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands
³Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands
⁴Department of Hematology, Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, Netherlands
⁵Dept of Hematology, Lymmcare, Cancer Center Amsterdam, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands
⁶Department of Radiology and Nuclear Medicine, Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, Netherlands

Colleen Isabelle¹, Kathleen McConnell^2*, Amy E Boles, BS^1*, Jonathan E Brammer, MD³, Robyn Berge^2*, Carla Portocarrero^4*, Nitin Chakravarti, PhD⁵, Pierluigi Porcu, MD⁶, Neda Nikbakht^7* and Anjali Mishra, PhD^8,9

¹Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA
²Thomas Jefferson University, Philadelphia
³The Ohio State University and Wexner Medical Center, Columbus, OH
⁴Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, PA
⁵Sidney Kimmel Cancer Center At Jefferson, Philadelphia, PA
⁶Sidney Kimmel Cancer Center at Jefferson Health, Thomas Jefferson University, Philadelphia, PA
⁷Thomas Jefferson University Hospital, Philadelphia, PA
⁸Department of Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA
⁹Sidney Kimmel Cancer Center, Thomas Jefferson University and Sidney Kimmel Cancer Center, Philadelphia, PA

Lei Nie, MD^1,2*, Yang Liu, PhD^2*, Changying Jiang, PhD², Yuxuan Che^2,3*, Jingling Jin, PhD^2,4*, Qingsong Cai, PhD^2*, Wei Wang, PhD^5*, Yijing Li, MS^2*, Alexa A Jordan, BS^5*, Joseph McIntosh, BS^5*, Jovanny Vargas^5*, Yixin Yao, PhD^2,3, Heng-Huan Lee, PhD^2* and Michael L. Wang, MD^2,6,7,8,9

¹Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, HOUSTON, TX
²Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Lymphoma and Myeloma, MD Anderson Cancer Center, Houston, TX
⁴Department of Lymphoma and Myeloma, M.D. Anderson cancer center, Houston, TX
⁵Lymphoma & Myeloma, MD Anderson Cancer Center, The University of Texas, Houston, TX
⁶Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
⁷University of Texas, MD Anderson Cancer Center, Houston, TX
⁸MD Anderson Cancer Center, Houston, TX
⁹MD Anderson Cancer Center, University of Texas, Houston, TX

Allison M. Bock, MD¹, Kerstin Wenzl, PhD¹, Matthew E. Stokes^2*, Joseph P. Novak^1*, Melissa A. Hopper, BS, MS¹, Jordan E. Krull¹, Abigail Dropik^1*, Vivekananda Sarangi^3*, Maria Ortiz, PhD^4*, Nicholas Stong, PhD^5*, C. Chris Huang, PhD^6*, Matthew J. Maurer, DSc⁷, Rebecca L. King^8*, Richard Curtis Godby, MD⁹, Umar Farooq, MD^10,11,12, Yucai Wang, MD, PhD¹³, Stephen M. Ansell, MD, PhD¹, Thomas M. Habermann, MD¹³, James R. Cerhan, MD, PhD³, Anita K. Gandhi, PhD¹⁴, Grzegorz (Greg) Nowakowski, MD¹⁵ and Anne J. Novak, PhD¹

¹Division of Hematology, Mayo Clinic, Rochester, MN
²Bristol Myers Squibb, Summit, NJ
³Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN
⁴Informatics and Predictive Sciences, Bristol Myers Squibb, Seville, Spain
⁵Informatics and Predictive Sciences, Bristol Myers Squibb, Summit, NJ
⁶Translational Medicine Hematology, Bristol Myers Squibb, Summit, NJ
⁷Department of Quantitative Health Sciences Research, Mayo Clinic, Rochester, MN
⁸Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, Rochester
⁹Division of Hematology, Mayo Clinic, Rochester, MN, USA, Rochester, MN
¹⁰Division of Hematology, Oncology, and Blood & Marrow Transplantation, University of Iowa, Iowa City, IA
¹¹Division of Hematology, Oncology, Blood & Marrow Transplantation, University of Iowa Hospitals and Clinics, Iowa City, IA
¹²University of Iowa Carver College of Medicine, Iowa City, IA
¹³Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN
¹⁴Translational Development and Diagnostics, Celgene Corporation, Summit, NJ
¹⁵Division of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, MN

Sonia N Wolf, MBBS PhD^1*, Patricia Watber, MSc^1*, Jana Haddow, RN^2*, Clare Greiller, PhD^1*, Graham Phillip Taylor, MB ChB, DSc, FRCP, FHEA^1,2*, Lucy Cook, MD PhD^1,2,3* and Aileen G Rowan^1*

¹Department of Infectious Disease, Imperial College London, London, United Kingdom
²National Centre for Human Retrovirology, Imperial College Healthcare NHS Trust, London, United Kingdom
³Department of Haematology, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom

Riccardo Moia, MD^1*, Chiara Favini, PhD^2*, Donatella Talotta, Dr^2*, Riccardo Dondolin, MD^2*, Mohammad Almasry, Dr.^2*, Riccardo Bruna, MD^2*, Samir Mouhssine, Mr.^2*, Irene Della Starza, PhD^3*, Roberta Soscia^4*, Alessio Bruscaggin, PhD⁵, Lodovico Terzi Di Bergamo^6*, Annalisa Andorno, MD^2*, Francesca Mercalli, MD^2*, Abdurraouf Mokhtar Mahmoud, MSc^2*, Clara Deambrogi, PhD^7*, Silvia Rasi, PhD^8*, Luigi Petrucci, MD^9*, Teresa Bellissimo^10*, Renzo Boldorini, MD^7*, Alice Di Rocco, MD^11*, Ilaria Del Giudice, MD, PhD^12*, Maurizio Martelli, MD^13*, Valter Gattei, MD¹⁴, Davide Rossi, MD, PhD¹⁵, Robin Foa, MD, PhD^3* and Gianluca Gaidano, MD, PhD⁸

¹Division of Hematology, Azienda Ospedaliero-Universitaria Maggiore della Carità di Novara, Novara, Italy
²Università del Piemonte Orientale, Novara, Italy
³Hematology, Department of Translational and Precision Medicine, "Sapienza" University of Rome, Rome, Italy
⁴Dept of Translational and Precision Medicine, "Sapienza", University of Rome, Rome, Italy
⁵Institute of Oncology Research, Università della Svizzera Italiana, Bellinzona, Switzerland
⁶Institute of Oncology Research, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland
⁷Università del Piemonte Orientale, Novara, ITA
⁸Division of Hematology, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy
⁹Hematology, Department of Translational and Precision Medicine, Sapienza University, Rome, Italy
¹⁰Dept of Translational and Precision Medicine, "Sapienza", University of Rome, Roma, Italy
¹¹Unit of Hematology, Azienda Ospedaliero-Universitaria Policlinico Umberto I, Roma, Italy
¹²'Sapienza' University, Hematology, Department of Translational and Precision Medicine, Rome, Italy
¹³Hematology, Department of Translational and Precision Medicine, Azienda Ospedaliera Policlinico Umberto I, Sapienza University of Rome, Roma, Italy
¹⁴Clinical and Experimental Onco-Hematology Unit, Centro Di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy
¹⁵Institute of Oncology Research, Bellinzona, Switzerland

Connie Lee Batlevi, MD, PhD¹, Grigorii Nos, MD^2*, Nikita Kotlov, MS^3*, Maria Sorokina, MD^4*, Michelle Okwali, MPH^5*, Alexander Bagaev, PhD^2*, Laure Michaud, MD^1*, Gunjan L. Shah, MD⁶, Roni Shouval, MD, PhD¹, Ana Alarcon Tomas^1*, Mark D. Ewalt, MD⁶, Ekaterina Belova^2*, Sandrine Degryse^2*, Cagdas Tazearslan^2*, Svetlana Podsvirova^2*, Anna Mooney Love^2*, Ekaterina Postovalova, PhD^2*, Nathan H. Fowler, MD², Miguel-Angel Perales, MD⁷, Heiko Schoder, MD, MBA^6*, Ahmet Dogan, MD, PhD⁸, Maria E. Arcila, MD^9*, Gilles Salles, MD, PhD¹ and Craig S. Sauter, MD^1*

¹Memorial Sloan Kettering Cancer Center, New York, NY
²BostonGene Corp., Waltham, MA
³BostonGene, Corp, Waltham, MA
⁴BostonGene Corp.., Waltham, MA
⁵Department of Medicine, Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY
⁶Memorial Sloan Kettering Cancer Center, New York
⁷Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
⁸Memorial Sloan-Kettering Cancer Center, New York
⁹Department of Pathology and Laboratory Medicine, Molecular Diagnostic Service, Memorial Sloan Kettering Cancer Center, New York, NY

Haya Shaalan^1*, Nicole Thomas², Merrill Boyle^3*, Barbara Meissner^3*, Marco A. Marra⁴, Christian Steidl^3*, David W. Scott, PhD, MD, FRACP, FRCPA^3,5, Laura K Hilton, PhD^3* and Ryan D. Morin^2,4

¹Department of Molecular Biology and Biochemistry, Simon Fraser University, Surrey, BC, Canada
²Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada
³Centre for Lymphoid Cancer, BC Cancer, Vancouver, BC, Canada
⁴Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada
⁵Division of Medical Oncology, University of British Columbia, Vancouver, BC, Canada

Zhiwei Liu, PhD^1*, Yang Luo^2*, Samuel Kirimunda^3*, Murielle Verboom^4*, Olusegun O Onabajo^1*, Mateus H Gouveia^5*, Martin Ogwang^6*, Patrick Kerchan^7*, Steven Reynolds^8*, Constance N Tenge^9*, Pamela A Were^10*, Robert T Kuremu^9*, Walter N Wekesa^9*, Nestory Masalu^11*, Esther Kawira^12*, Tobias Kinyera^13*, Isaac Otim^14*, Ismail D Legason^14*, Hadijah Nabalende^13*, Herry Dhudha^12*, Leona W Ayers^15*, Robert J Biggar^1*, Kishor G. Bhatia, PhD, FRCPath^16*, James J Goedert^1*, Nathan Cole^17*, Wen Luo^17*, Jia Liu^18*, Michelle Manning^17*, Belynda Hicks^19*, Ludmila Prokunina-Olsson, PhD^20*, George Chagaluka^21*, Tom Johnston^22*, Nora Mutalima^23*, Eric Borgstein^21*, George N Liomba^21*, Steve Kamiza^21*, Nyengo Mkandawire^21*, Collins Mitambo^24*, Elizabeth Molyneux^25*, Robert Newton^22*, Ann W Hsing, PhD^26*, James E Mensah^27*, Ruth M Pfeiffer^1*, Amy Hutchinson^18*, Carrington Mary, PhD^28*, Meredith Yeager, PhD^18*, Moses Joloba^3*, Rainer Blasczyk^4*, Stephen J. Chanock, MD^29*, Soumya Raychaudhuri^30* and Sam M. Mbulaiteye, MBBChir, MPhil^31*

¹National Cancer Institute, Rockville, MD
²Broad Institute of MIT and Harvard, Boston, MA
³Makerere University, Kampala, Uganda
⁴Institute of Transfusion Medicine and Transplant Engineering, Hanover, Germany
⁵National Institutes of Health, Bethesda, MD
⁶EMBLEM study, ST. MARY'S HOSPITAL LACOR, Gulu, UGA
⁷African Field Epidemiology Network, Kampala, Uganda
⁸NIAID/NIH, Dulles, VA
⁹Moi University College of Health Sciences, Eldoret, Kenya
¹⁰Academic Model Providing Access To Healthcare (AMPATH), Eldoret, Kenya
¹¹Bugando Medical Center, Mwanza, Tanzania, United Republic of
¹²Shirati Health, Education, and Development Foundation, Shirati, Tanzania, United Republic of
¹³ST. MARY'S HOSPITAL LACOR, Gulu, UGA
¹⁴St. Mary’s Hospital, Lacor, Gulu, Uganda
¹⁵The Ohio State University, Columbus, OH
¹⁶NCI Cancer Diagnosis Program, National Institute Of Health, MD
¹⁷Frederick National Laboratory for Cancer Research, Frederick, MD
¹⁸Cancer Genomics Research Laboratory, Frederick National Laboratory, Frederick, MD
¹⁹Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD
²⁰Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD
²¹University of Malawi, Blantyre, Malawi
²²University of York, York, GBR
²³University of York, York, United Kingdom
²⁴Research Department, Ministry of Health, Lilongwe, Malawi
²⁵Queen Elizabeth Central Hospital, Blantyre, MWI
²⁶Stanford University, Palo Alto, CA
²⁷University of Ghana Medical School, Accra, Ghana
²⁸Basic Science Program, Frederick National Laboratory for Cancer Research, Frederick, MD
²⁹Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD
³⁰Broad Institute of MIT and Harvard, Cambridge, MA
³¹Division of Cancer Epidemiology and Genetics, National Cancer Institute, Silver Spring, MD

Xianhuo Wang, MD^1*, Tingting Zhang^1*, Yaxiao Lu^1*, Yue Fei^1*, Lanfang Li^1*, Lihua Qiu^1*, Zhengzi Qian^1*, Shiyong Zhou^1*, Kai Fu^2,3 and Huilai Zhang, M.D.^1*

¹Department of Lymphoma, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China
²Department of Lymphoma, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’s Clinical Research Center for Cancer, Tianjin, China
³Pathology, Univ. of Nebraska Medical Ctr., Omaha, NE

Joanne Lee, MBBS^1,2*, Hossein Tabatabaeian^3*, Michelle Limei Poon, MBBS, MRCP^1,2*, Nagavalli Somasundaram, MBBS, MRCP^4,5, Liu Xin, M.A. in Counselling and Guidance, MSc in Biomedical Engineering^1*, Yi Ching Yuen, BPharm, MClinPharm^6*, Chia Meng Teoh, MBBS^7*, Benedict Yan, MBBS^8*, Esther Hian Li Chan, MBBS^1*, Yen Lin Chee, MBChB PhD^1,2, Sanjay De Mel, BSc, FRCPath, MRCP^1*, Bin Zhang^3,9,10*, Xiao Hong Chew^3*, Tiffany Tang, MBBS, MRCP^5*, Chiea Chuen Khor, M.D, PhD^11*, Joanne Yuen Yie Ngeow, BMedSci, MBBS, MRCP, FAMS^5,12,13*, Choon Kiat Ong, PhD^14,15, Soon Thye Lim, MBBS^16,17*, Wee Joo Chng, MBChB PhD^3,18,19, E Shyong Tai, MB ChB, MRCP, FRCP, PhD^2,20*, Kee Yuan Ngiam^2,21*, Soo Chin Lee, MBBS, MRCP, M.Med, FRCP, FAMS^1,3*, Boon Cher Goh, MBBS, MRCP, M.Med, FRCP^1,2,3,22*, Anand Devaprasath D. Jeyasekharan^1,2,3*, Yvonne Tay^3,17* and Folefac Aminkeng, BMLS, MSc, PhD^2,15*

¹National University Health System, National University Cancer Institute, Singapore, Singapore
²Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, Singapore
³Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore
⁴Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore
⁵Duke–NUS Medical School, National University of Singapore (NUS), Singapore, Singapore
⁶Department of Pharmacy, National University Hospital, Singapore (NUH), Singapore, SGP
⁷Division of Respiratory Medicine, University Medicine Cluster, National University Health System, Singapore, Singapore
⁸Molecular Diagnosis Centre, Department of Laboratory Medicine, National University Hospital, Singapore, Singapore, Singapore
⁹Computer Science Program, Computer, Electrical and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia, Thuwal, Saudi Arabia
¹⁰KAUST Computational Bioscience Research Center, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia
¹¹Genome Institute of Singapore (GIS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore
¹²Lee Kong Chian School of Medicine, Nanyang Technological University, singapore, Singapore
¹³Institute of Molecular and Cell Biology, Agency of Science Technology and Research (A*STAR), Singapore, Singapore
¹⁴Division of Cellular and Molecular Research, National Cancer Centre Singapore., Singapore, Singapore
¹⁵Department of Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore, Singapore
¹⁶Director's office, National Cancer Centre Singapore, Singapore, Singapore
¹⁷Office of Education, Duke-NUS Medical School, Singapore, Singapore
¹⁸Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
¹⁹National University Cancer Institute, Singapore, Singapore
²⁰Division of Endocrinology, University Medicine Cluster, National University Health System (NUHS), Singapore, Singapore
²¹Department of Biomedical Informatics (DBMI), Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, Singapore
²²Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, Singapore

Weiyin Zhou^1,2*, Anja Pfaus^3*, Martin Ogwang^4*, Wen Luo^5,6*, Patrick Kerchan^7*, Steven Reynolds^8*, Constance N Tenge^9*, Pamela A Were^10*, Robert T Kuremu^9*, Walter N Wekesa^9*, Nestory Masalu^11*, Esther Kawira^12*, Tobias Kinyera^13*, Isaac Otim^14*, Ismail D Legason^14*, Hadijah Nabalende^13*, Leona W Ayers^15*, Kishor Bhatia, PhD^16*, James J Goedert^17*, Nathan Cole^6*, Belynda Hicks^18*, Kristine Jones^2*, Michael Hummel^19*, Matthias Schlesner, PhD^20*, George Chagaluka^21*, Nora Mutalima^22*, Eric Borgstein^21*, George N Liomba^21*, Steve Kamiza^21*, Nyengo Mkandawire^21*, Collins Mitambo^23*, Elizabeth Molyneux^24*, Robert Newton^25*, Selina Glaser^26*, Michelle Manning^6*, Amy Hutchinson^2*, Ann W Hsing, PhD^27*, Yao Tettey^28*, Andrew Anthony Adjei^28*, Stephen J. Chanock, MD^1*, Reiner Siebert, Prof. Dr.^29*, Meredith Yeager, PhD^2*, Mitchell Machiela, PhD^1* and Sam M. Mbulaiteye, MBBChir, MPhil^30*

¹Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD
²Cancer Genomics Research Laboratory, Frederick National Laboratory, Frederick, MD
³Institute of Human Genetics, Ulm University Medical Center, Ulm University, Ulm, Germany
⁴EMBLEM study, ST. MARY'S HOSPITAL LACOR, Gulu, UGA
⁵Division of Cancer Epidemiology and Genetics,, National Cancer Institute, Rockville, MD
⁶Frederick National Laboratory for Cancer Research, Frederick, MD
⁷African Field Epidemiology Network, Kampala, Uganda
⁸NIAID/NIH, Dulles, VA
⁹Moi University College of Health Sciences, Eldoret, Kenya
¹⁰Academic Model Providing Access To Healthcare (AMPATH), Eldoret, Kenya
¹¹Bugando Medical Center, Mwanza, Tanzania, United Republic of
¹²Shirati Health, Education, and Development Foundation, Shirati, Tanzania, United Republic of
¹³ST. MARY'S HOSPITAL LACOR, Gulu, UGA
¹⁴St. Mary’s Hospital, Lacor, Gulu, Uganda
¹⁵The Ohio State University, Columbus, OH
¹⁶Cancer Genetics Inc, Rutherford, NJ
¹⁷National Cancer Institute, Rockville, MD
¹⁸Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD
¹⁹Institute of Pathology, Charité – University Hospital Berlin, Berlin, Germany
²⁰Faculty of Applied Computer Sciences, Biomedical Informatics, Data Mining and Data Analytics, Augsburg University, Augsburg, Germany
²¹University of Malawi, Blantyre, Malawi
²²University of York, York, United Kingdom
²³Research Department, Ministry of Health, Lilongwe, Malawi
²⁴Queen Elizabeth Central Hospital, Blantyre, MWI
²⁵University of York, York, GBR
²⁶Institute of Human Genetics, Ulm University and Ulm University Medical Center, Ulm, DEU
²⁷Stanford University, Palo Alto, CA
²⁸University of Ghana Medical School, Accra, Ghana
²⁹Institute of Human Genetics, Ulm University and Ulm University Medical Center, Ulm, Germany
³⁰Division of Cancer Epidemiology and Genetics, National Cancer Institute, Silver Spring, MD

Karan Chohan^1*, Jonas Paludo, MD², Surendra Dasari, PhD^3*, Jithma P. Abeykoon, MD², Prashant Kapoor, MD², Esteban Braggio, PhD⁴, Michelle K. Manske, MS, BS^2*, Aneel Paulus, MD⁵, Craig B. Reeder, MD⁴, Sikander Ailawadhi⁵, Asher Chanan-Khan, MD⁵, Robert A. Kyle, MD⁶, Morie A Gertz, MD², Anne J. Novak, PhD² and Stephen M. Ansell, MD, PhD²

¹Department of Medicine, Mayo Clinic, Rochester, MN
²Division of Hematology, Mayo Clinic, Rochester, MN
³Department of Health Sciences Research, Mayo Clinic, Rochester, MN
⁴Division of Hematology and Medical Oncology, Mayo Clinic, Scottsdale, AZ
⁵Division of Hematology and Oncology, Mayo Clinic, Jacksonville, FL
⁶Division of Hematology, Mayo Clinic, Stabile 6-28, Rochester, MN

Brett Collinge^1*, Susana Ben-Neriah, MSc^1*, Laura K Hilton, PhD^1*, Waleed Alduaij, MD, PhD^1*, Tracy Tucker^2*, Graham W Slack, MD, PhD^1*, Pedro Farinha, MD, PhD^1*, Jeffrey W. Craig, MD, PhD^1*, Merrill Boyle^1*, Barbara Meissner^1*, Kelly Mekwunye^1*, Diego Villa, MD¹, Alina S. Gerrie, MD, MPH, FRCPC¹, Laurie H. Sehn, MD, MPH¹, Kerry J. Savage, MD, MSc, FRCPC¹, Ryan D. Morin^1,3, Andrew J. Mungall, PhD^4*, Christian Steidl, MD¹ and David W. Scott, PhD, MD, FRACP, FRCPA¹

¹Centre for Lymphoid Cancer, BC Cancer, Vancouver, BC, Canada
²Cancer Genetics & Genomics Laboratory, BC Cancer, Vancouver, BC, Canada
³Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada
⁴Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada

Mayumi Yoshimori, PhD^1*, Ayaka Ohashi, PhD^2,3,4*, Kotaro Yoshioka, MD, PhD^5*, Takanori Yokota, MD, PhD^6*, Norio Shimizu, PhD^7*, Miwako Nishio, PhD^3* and Ayako Arai, MD, PhD^3,4,8

¹Department of Laboratory Molecular Genetics of Hematology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Bunkyo-Ku, TKY, Japan
²Department of Frontier Medicine, Institute of Medical Science, St. Marianna University School of Medicine, Kanagawa, Japan
³Department of Laboratory Molecular Genetics of Hematology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
⁴Division of Hematology and Oncology, Department of Internal Medicine, St. Marianna University School of Medicine, Kanagawa, Japan
⁵Department of Neurology and Neurological Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan
⁶Tokyo Medical and Dental University, Department of Neurology and Neurological Science, Graduate School of Medical and Dental Sciences, Tokyo, Japan
⁷Center for Stem Cell and Regenerative Medicine, Division of Advanced Multidisciplinary Research, Tokyo Medical and Dental University, Tokyo, Japan
⁸Department of Hematology, Tokyo Medical and Dental University, Tokyo, Japan

Xingtong Wang, MD¹, Wei Guo, MD/PhD^1*, Xiaoju Shi, MD/PhD^2*, Jia Li¹, Min Tan^3*, Yan Li, MD/PhD^3* and Ou Bai, MD/PhD^1*

¹Department of Hematology, The First Hospital of Jilin University, Changchun, China
²Department of Hepatobiliary and Pancreatic Surgery, The first hospital of Jilin University, Changchun, China
³Department of Surgery, University of Louisville School of Medicine, LOUISVILLE, KY

Connie Lee Batlevi, MD, PhD¹, Esther Drill, DrPH^2*, Michelle Okwali, MPH^3*, Ryan Ptashkin, MS^4*, Philip C Caron, MD, PhD³, Zachary D. Epstein-Peterson, MD³, Lorenzo Falchi, MD³, Audrey Hamilton, MD^3*, Paul A. Hamlin, MD³, Steven M. Horwitz, MD³, Andrew M. Intlekofer, MD, DPhil³, William T. Johnson, DO³, Niloufer Khan, MD³, Anita Kumar, MD³, Jennifer Kimberly Lue, MD³, Matthew J. Matasar, MD, MS³, Alison J. Moskowitz, MD³, Ariela Noy, MD³, Colette Owens, MD³, Maria Lia Palomba⁵, David J. Straus, MD³, Santosha Vardhana, MD, PhD³, Andrew D. Zelenetz, MD, PhD⁶, Maria E. Arcila, MD^7*, Ahmet Dogan, MD, PhD⁸, Venkatraman Seshan, PhD^2*, Gilles Salles, MD, PhD³, Ahmet Zehir, PhD^4* and Anas Younes, MD³

¹Lymphoma Service, Cellular Therapy Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, NEW YORK, NY
²Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY
³Department of Medicine, Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY
⁴Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY
⁵Lymphoma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
⁶Memorial Sloan Kettering Cancer Center, New York, NY
⁷Molecular Diagnostic Service, Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY
⁸Department of Pathology and Laboratory Medicine, Hematopathology Service, Memorial Sloan Kettering Cancer Center, New York, NY

Ruth Salim, BSc.med.^1,2,3*, Simon Husby, MD, PhD^1,2*, Christian Winther Eskelund, MD, PhD^4*, David W. Scott, PhD, MD, FRACP, FRCPA⁵, Harald Holte, MD, PhD⁶, Arne Kolstad, MD, PhD^7*, Riikka Räty, MD, PhD^8*, Sara Ek, PhD, Professor^9*, Mats Jerkeman, MD, PhD¹⁰, Christian H. Geisler, MD, PhD¹, Lasse Sommer Kristensen, PhD, Assistant professor^11*, Mette Dahl, MD, PhD^1,2* and Kirsten Grønbæk^1,3,12

¹Department of Hematology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
²Grønbæk Group, Biotech Research and Innovation Centre, BRIC, University of Copenhagen, Copenhagen, Denmark
³Institute of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
⁴Genmab, Copenhagen, Denmark
⁵Centre for Lymphoid Cancer, BC Cancer Research Centre, Vancouver, BC, Canada
⁶Department of Oncology, Oslo University Hospital, Oslo, Norway
⁷Oslo University Hospital, Oslo, Norway
⁸Department of Hematology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland
⁹Department of Immunotechnology, Lund University, Lund, Sweden
¹⁰Department of Oncology, Lund University and Skane University Hospital, Lund, Sweden
¹¹Department of Biomedicine, Aarhus University, Denmark, Aarhus C, Denmark
¹²Biotech Research and Innovation Center (BRIC), University of Copenhagen, Copenhagen, Denmark

Renee P Stokowski, PhD^1*, Ehsan Tabari, PhD^2*, Patrick Bogard, PhD^2*, Coleen Hacker, MS^2*, Olga K Kameneva, PhD^2*, Tieming Ji, PhD^2*, Li Teng, PhD^2*, Vladislava Melnikova, MD, PhD^2*, Ron McCord, PhD^3*, Elizabeth A Punnoose, PhD³, Robert Loberg, PhD^2* and Junaid Shabbeer, PhD^2*

¹Roche Molecular Diagnostics, San Jose, CA
²Roche Molecular Diagnostics, Pleasanton, CA
³Genentech, Inc., South San Francisco, CA

Christopher K Rushton^1*, Ryan N Rys, BSc, BA^2,3*, Elizabeth Chavez, BSc, Cg RT^4*, Laura K Hilton, PhD^4*, Miguel Alcaide, PhD^5*, Kostiantyn Dreval^6*, Matthew Cheung, BSc^1*, Manuela Cruz^1*, Krysta M. Coyle, PhD¹, Barbara Meissner^4*, Susana Ben-Neriah, MSc^4*, Neil R. Michaud, PhD^7*, Scott Daigle^8*, Jordan Davidson, BSc^1*, Jasper Wong^4*, Annette E. Hay⁹, Michael D. Jain, MD, PhD¹⁰, Lois E. Shepherd⁹, Marco A. Marra⁴, John Kuruvilla, MD¹¹, Michael Crump⁹, Koren Kathleen Mann, PhD¹², Sarit Assouline¹², Christian Steidl^4*, David W. Scott, PhD, MD, FRACP, FRCPA⁴, Nathalie A. Johnson, MD, PhD,^12,13 and Ryan D. Morin^4,14

¹Department of Molecular Biology & Biochemistry, Simon Fraser University, Burnaby, BC, Canada
²Jewish General Hospital, Lady Davis Institute For Medical Research, Montreal, QC, Canada
³Department of Physiology, McGill University, Montreal, QC, Canada
⁴Centre for Lymphoid Cancer, BC Cancer, Vancouver, BC, Canada
⁵SAGA Diagnostics, Lund, Sweden
⁶Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada
⁷Immunitas Therapeutics, Waltham, MA
⁸Epizyme, Cambridge, MA
⁹Canadian Cancer Trials Group, Queen's University, Kingston, ON, Canada
¹⁰Department of Blood and Marrow Transplant and Cellular Immunotherapy, H. Lee Moffitt Cancer Center, Tampa, FL
¹¹University Health Network, Princess Margaret Cancer Center, Toronto, ON, Canada
¹²Jewish General Hospital, Lady Davis Institute for Medical Research, Montreal, QC, Canada
¹³Department of Medicine, McGill University, Montreal, QC, Canada
¹⁴Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada

Erik Van Dijk^1*, Jurriaan Janssen^2*, Matias Mendeville^2*, G. Tjitske Los-De Vries^2*, Margaretha GM Roemer, PhD^2*, Phylicia Stathi^2*, Julia Richter, PhD^3*, Yong Soo Kim, PhD^2*, Wolfram Klapper, MD^4*, Ulrich Dührsen, Prof, MD, PhD^5*, Andreas Hüttmann, MD⁶, P. J Lugtenburg, MD^7,8, Josée M. Zijlstra, MD PhD⁹, Marie Jose Kersten, MD, PhD^8,10, Daphne de Jong, MD, PhD^2*, Martine E.D. Chamuleau, MD, PhD^8,10 and Bauke Ylstra^2*

¹Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands
²Amsterdam UMC, Vrije Universiteit Amsterdam, department of Pathology, Cancer Center Amsterdam, Amsterdam, Netherlands
³Department of Pathology, Hematopathology Section, University Hospital Schleswig-Holstein, Christian-Albrecht-University of Kiel, Kiel, Germany
⁴Department of Pathology, Hematopathology Section and Lymph Node Registry, Universitätsklinikum Schleswig-Holstein, Kiel, Germany
⁵Department of Hematology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
⁶Department of Hematology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, NRW, Germany
⁷Erasmus MC Cancer Institute, Department of Hematology, Rotterdam, Netherlands
⁸on behalf of HOVON/LLBC (Lunenburg Lymphoma Phase I/II Consortium), Amsterdam, Netherlands
⁹Department of Hematology, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, the Netherlands, Amsterdam, Netherlands
¹⁰Amsterdam UMC, Vrije Universiteit Amsterdam, department of Hematology, Cancer Center Amsterdam, Amsterdam, Netherlands

Xianhuo Wang, MD^1*, Yaxiao Lu^1*, Sicong Zhang^1*, Lanfang Li^1*, Lihua Qiu^1*, Zhengzi Qian^1*, Shiyong Zhou^1*, Kai Fu^2,3 and Huilai Zhang, M.D.^4*

¹Department of Lymphoma, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China
²Department of Lymphoma, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’s Clinical Research Center for Cancer, Tianjin, China
³Pathology, Univ. of Nebraska Medical Ctr., Omaha, NE
⁴Tianjin Medical University Cancer Institute and Hospital, Tianjin, China

Miriam Verdú Bou, PhD^1*, Maria Joao Baptista, PharmD, PhD^1*, Aleix Mendez Lopez^2*, Gustavo Tapia, MD, Prof.^3*, Marcelo Lima Ribeiro, PhD^4*, Gaël Roué, PhD^4*, Jose Luis Mate, MD, Prof.^3*, Pau Abrisqueta, MD, PhD^5*, Mariana Bastos-Oreiro, MD, PhD^6*, Miguel Alcoceba, PhD^7*, Eva González Barca^8*, Fina Climent, PhD^9*, Antonio Salar, MD, PhD^10*, Juan-Manuel Sancho, MD, PhD^1,2*, Fabian Frontzek, MD^11*, Annette M. Staiger, PhD^12*, German Ott, Prof.^12*, Manuel Castro De Moura^13*, Georg Lenz, MD, Prof.¹¹ and Jose Tomas Navarro, MD, PhD^1,2*

¹Lymphoid neoplasms Group, Josep Carreras Leukemia Research Institute, Autonomous University of Barcelona, Badalona, Spain
²Department of Hematology, Institut Catala d’Oncologia (ICO)-Germans Trias i Pujol University Hospital, Autonomous University of Barcelona, Badalona, Spain
³Department of Pathology, Germans Trias i Pujol University Hospital, Autonomous University of Barcelona, Badalona, Spain
⁴Lymphoma translational group, Josep Carreras Leukemia Research Institute, Badalona, Spain
⁵Department of Hematology, Vall d’Hebron University Hospital, Barcelona, Spain
⁶Department of Hematology, Gregorio Marañón Hospital, Madrid, Spain
⁷Department of Hematology, University Hospital of Salamanca (HUS/IBSAL), CIBERONC, Cancer Research Institute of Salamanca-IBMCC (USAL-CSIC), Salamanca, Salamanca, Spain
⁸Department of Hematology, ICO-Duran i Reynals Hospital, Bellvitge Biomedical Research Institute (IDIBELL), University of Barcelona, Hospitalet de Llobregat, Spain
⁹Department of Pathology, Bellvitge University Hospital-IDIBELL, Hospitalet de Llobregat, Spain
¹⁰Department of Hematology, Hospital del Mar, Barcelona, ., Spain
¹¹Department of Medicine A, Department of Hematology, Oncology and Pneumology, University Hospital Münster, Münster, Germany
¹²Department of Clinical Pathology, Robert Bosch Hospital, Stuttgart, Germany
¹³Department of Bioinformatics, Josep Carreras Leukemia Research Institute, Badalona, Spain

Linlin Xu, PhD^1*, Mazyar Shadman, MD², Anusha Ponakala^1*, Ian W. Flinn, MD PhD³, Moshe Yair Levy, MD⁴, Ryan Porter, MD^5*, John M. Burke, MD⁶, Syed F. Zafar, MD⁷, Jennifer L. Cultrera, MD^8*, Jamal Misleh, MD^9*, Edwin C. Kingsley, MD¹⁰, Habte A. Yimer¹¹, Benjamin Freeman, MD^12*, Arvind Chaudhry, MD, PhD^13*, Praveen K. Tumula^14*, Mitul Gandhi, MD¹⁵, Aileen Cohen^1*, Dih-Yih Chen^1*, Sudhir Manda, MD¹⁶, Jeff P. Sharman, MD¹⁷ and Vanitha Ramakrishnan, PhD^1*

¹BeiGene (Beijing) Co., Ltd., Beijing, China and BeiGene USA, Inc., San Mateo, CA
²Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA
³Sarah Cannon Research Institute/Tennessee Oncology, Nashville, TN
⁴Texas Oncology-Baylor Charles A. Sammons Cancer Center, Dallas, TX
⁵SSM Health Dean Medical Group, Madison, WI
⁶Rocky Mountain Cancer Centers, Aurora, CO
⁷Florida Cancer Specialists & Research Institute, Fort Myers, FL
⁸Florida Cancer Specialists & Research Institute, Leesburg, FL
⁹Medical Oncology Hematology Consultants PA, Newark, DE
¹⁰Comprehensive Cancer Centers of Nevada, Las Vegas, NV
¹¹Texas Oncology, Tyler, TX
¹²Summit Medical Group, Florham Park, NJ
¹³Summit Cancer Centers, Spokane, WA
¹⁴Texas Oncology, Amarillo, TX
¹⁵Virginia Cancer Specialists, Gainesville, VA
¹⁶Arizona Oncology/US Oncology Research, Tucson, AZ
¹⁷Willamette Valley Cancer Institute and Research Center, Eugene, OR

Marie-France Gagnon, MD¹, Alan R Penheiter^2*, Sarah H Johnson, MS^2*, James B Smadbeck, PhD^2*, Dorsay Sadeghian, MD^2*, Faye R Harris, MS^2*, Giannoula Karagouga, MS^2*, Alexa McCune^2*, Nicole L Hoppman, PhD¹, Xinjie Xu, PhD³, Rhett P. Ketterling, MD^3*, Patricia Greipp, DO³, Jess F Peterson, MD³, George Vasmatzis, PhD^2*, Rebecca L. King, MD³ and Linda B. Baughn, Ph.D³

¹Division of Laboratory Genetics and Genomics, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
²Center for Individualized Medicine, Biomarker Discovery, Mayo Clinic, Rochester, MN
³Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN

Nick Veltmaat, MSc^1*, Geok Wee Tan^2*, Johanna A.A. Bult, BSc^3*, Yujie Zhong, MSc^4*, Wouter J. Plattel, MD PhD^5*, Rogier Mous^6*, Pim Mutsaers, MD^7*, Wendy B.C. Stevens, MD^8*, Joost S.P. Vermaat, MD, PhD⁹, Martine E.D. Chamuleau, MD, PhD¹⁰, Arjan Diepstra, M.D., Ph.D.¹¹, Anke Van Den Berg, PhD¹¹, Filipe Montes De Jesus, MD^12* and Marcel Nijland, MD, PhD^13*

¹Department of Hematology, Groningen, Netherlands
²University Medical Center Groningen, Groningen, Netherlands
³Department of Hematology, University Medical Center Groningen, Groningen, Netherlands
⁴Department of Pathology and Medical Biology, Groningen, Netherlands
⁵Department of Hematology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands
⁶Department of Hematology, Universitair Medisch Centrum Utrecht, Utrecht, NH, Netherlands
⁷Department of Hematology, Erasmus MC Cancer Center, Rotterdam, Netherlands
⁸Department of Hematology, Radboud University Medical Center, Nijmegen, Netherlands
⁹Department of Hematology, Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands
¹⁰Department of Hematology, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam, Netherlands
¹¹Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands
¹²Department of Nuclear Medicine, University Medical Center Groningen, Groningen, AL, Netherlands
¹³Department of Hematology, University Medical Center Groningen and University of Groningen, Groningen, Netherlands