Wolfgang Kern, MD¹, Prashant R. Tembhare, MD², Reza Nejati, MD^3*, Fatima Zahra Jelloul, MD^4*, Wencke Walter, PhD^1*, Joseph D. Khoury, MD, FCAP^5,6 and Torsten Haferlach, MD¹

¹MLL Munich Leukemia Laboratory, Munich, Germany
²Hematopathology Lab, Tata Memorial Centre, Affiliated to Homi Bhabha National Institute, Mumbai, India
³Department of Pathology, Fox Chase Cancer Center, Philadelphia, PA
⁴Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
⁵University of Nebraska Medical Center, Omaha, NE
⁶The University of Texas MD Anderson Cancer Center, Houston

Jan Philipp Bewersdorf, MD^1,2, Vanessa Hasle^3*, Rory M. Shallis, MD⁴, Ethan G. Thompson, PhD^3*, Daniel Lopes de Menezes, PhD^3*, Shelonitda Rose⁵, Isaac W. Boss, PhD^6*, Stephanie Halene, MD⁷, Torsten Haferlach, MD⁸, Brian Fox^9* and Amer M. Zeidan, MD¹⁰

¹Department of Medicine; Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY
²Department of Internal Medicine, YALE UNIVERSITY SCHOOL OF MEDICINE, New Haven, CT
³Bristol Myers Squibb, Princeton, NJ
⁴Department of Internal Medicine, School of Medicine and Yale Cancer Center, Yale University, New Haven, CT
⁵Bristol Myers Squibb, Summit, NJ
⁶Translational Research, Bristol Myers Squibb, Seattle, WA
⁷Section of Hematology, Department of Internal Medicine, Yale University School of Medicine and Yale Cancer Center, New Haven, CT
⁸MLL Munich Leukemia Laboratory, Munich, Germany
⁹Bristol-Myers Squibb Company, Princeton, NJ
¹⁰Yale University and Yale Cancer Center, New Haven, CT

Sayantanee Dutta, PhD^1*, Paul Kerbs, Dr.^2,3,4,5*, Maja Rothenberg-Thurley, PhD^6*, Bianka Ksienzyk^7,8*, Stefan Krebs, PhD^9,10*, Helmut Blum^9*, Karsten Spiekermann^2,3,11,12,13, Klaus H Metzeler, MD¹⁴, Tobias Herold, MD¹⁵, Sebastian Vosberg, PhD^16* and Philipp A. Greif^3,5,17

¹Hematology, Medical University Graz, Graz, Austria
²German Cancer Research Center (DKFZ), Heidelberg, Germany
³German Consortium for Translational Cancer Research (DKTK), Partner Site Munich, Munich, Germany
⁴Ludwig Maximilian University of Munich, Munich, Germany
⁵German Cancer Consortium (DKTK), Munich, Germany
⁶Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany
⁷Experimental Leukemia and Lymphoma Research, Department of Medicine III, University Hospital, LMU Munich, Munich, Germany
⁸Department of Medicine III, University Hospital, LMU Munich, Munich, Germany
⁹Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, Munich, Germany
¹⁰Laboratory for Functional Genome Analysis, Gene-Center, Ludwig-Maximilians-University, Munich, Germany
¹¹Experimental Leukemia and Lymphoma Research (ELLF), Department of Internal Medicine III, University Hospital, LMU Munich, Munich, Germany
¹²Department of Medicine III, Laboratory for Leukemia Diagnostics (LfL), University Hospital, LMU Munich, Munich, Germany
¹³German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany
¹⁴Department of Hematology, Cell Therapy and Hemostaseology, University Hospital Leipzig, Leipzig, Germany
¹⁵Laboratory for Leukemia Diagnostics, Department of Medicine III, Ludwig-maximilians-Universitaet (LMU), Munich, Bavaria, Germany
¹⁶Division of Oncology, Medical University of Graz, Graz, Austria
¹⁷Department of Medicine III, University Hospital Grosshadern, Ludwig-Maximilians University, Munich, Germany

Atsushi Marumo, MD^1*, Satoshi Wakita, MD, PhD^1*, Kaoru Morita, MD, PhD^2*, Shinichi Kako³, Takashi Toya⁴, Yuho Najima⁵, Noriko Doki^6*, Junya Kanda, MD, PhD⁷, Junya Kuroda, MD, PhD⁸, Shin-Ichiro Mori, MD^9*, Atsushi Satake, MD, PhD¹⁰, Kensuke Usuki, MD, PhD¹¹, Toshimitsu Ueki, MD^12*, Nobuhiko Uoshima, MD, PhD^13*, Yutaka Kobayashi, MD, PhD^14*, Eri Kawata, MD, PhD¹⁵, Kazutaka Nakayama^16*, Yuhei Nagao^17*, Katsuhiro Shono, MD, PhD^17*, Motoharu Shibusawa^18*, Jiro Tadokoro^19*, Masao Hagihara, MD^20*, Hitoji Uchiyama, MD, PhD^21*, Naoyuki Uchida, MD, PhD²², Yasushi Kubota, MD, PhD^23*, Shinya Kimura, MD, PhD^24*, Hisao Nagoshi^25*, Tatsuo Ichinohe²⁶, Saiko Kurosawa^27*, Sayuri Motomura, MD, PhD²⁸, Hashimoto Akiko, MD^29*, Hideharu Muto, MD, PhD^30*, Eriko Sato, MD, PhD^31*, Masao Ogata, MD, PhD^32*, Kenjiro Mitsuhashi^33*, Jun Ando, MD, PhD^34*, Haruko Tashiro, M.D., Ph.D.^35*, Masahiro Sakaguchi^1*, Shunsuke Yui^1*, Kunihito Arai^1*, Tomoaki Kitano^1*, Miho Miyata^36*, Takahiro Fukuda^37*, Yoshinobu Kanda, MD, PhD³⁸ and Hiroki Yamaguchi, MD, PhD¹

¹Department of Hematology, Nippon Medical School, Tokyo, Japan
²Division of Hematology, Jichi Medical University, Tochigi, Japan
³Division of Hematology, Jichi Medical University Saitama Medical Center, Saitama, Japan
⁴Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan
⁵Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Tokyo, TKY, Japan
⁶Division of Hematology, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan
⁷Department of Hematology and Oncology, Kyoto University, Kyoto, Japan
⁸Division of Hematology and Oncology, Deparment of Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan
⁹St. Luke's International Hospital, Chuo-Ku, TKY, JPN
¹⁰Kansai Medical University, Osaka, Japan
¹¹Department of Hematology, NTT Medical Center Tokyo, Tokyo, Japan
¹²Nagano Redcross Hospital, Nagano, JPN
¹³Department of Hematology, Japanese Red Cross Kyoto Daini Hospital, Kyoto, Japan
¹⁴Department of Hematology, Japan Red Cross Kyoto Daini Hospital, Kyoto, Japan
¹⁵Department of Hematology, Panasonic Health Insurance Organization, Matsushita Memorial Hospital, Osaka, KYO, Japan
¹⁶Yokohama Minami Kyousai Hospital, Kanagawa, Japan
¹⁷Department of Hematology, Chiba Aoba Municipal Hospital, Chiba, Japan
¹⁸Department of Hematology, IMS group Shinmatsudo Central General Hospital, Chiba, Japan
¹⁹Shinmatsudo Central General Hospital, Matsudo-Shi, Chiba-Ken, JPN
²⁰Department of Hematology, EIJU GENERAL HOSPITAL, Taito-Ku, Japan
²¹Department of Hematology, Japanese Red Cross Kyoto Daiichi Hospital, Kyoto, Japan
²²Department of Hematology, Federation of National Public Service Personnel Mutual Aid Associations, Toranomon Hospital, Tokyo, Japan
²³Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Saga, Japan
²⁴Saga University, Saga, Japan
²⁵Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan
²⁶Department of Hematology and Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan
²⁷Department of Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital, Tokyo, Japan
²⁸Tokyo Metropoloitan Tama-Hokubu Medical Center, Higashimurayama-shi, JPN
²⁹Kobe City Nishi-Kobe Medical Center,, Hyogo, Japan
³⁰Division of hematology, Tokyo Metropolitan Otsuka Hospital, Tokyo, Japan
³¹Department of Hematology, Juntendo University Nerima Hospital, Tokyo, Japan
³²Department of Hematology, Oita University, Yufu, Japan
³³Saitama Red Cross Hospital, Saitama, Japan
³⁴Department of Hematology, Juntendo University of Medicine, Tokyo, Japan
³⁵Department of Hematology/Oncology, Teikyo University School of Medicine, Itabashi-ku, Japan
³⁶Department of Hematology, Nippon Medical School, Tokyo, JPN
³⁷Hematopoietic Stem Cell Transplantation Division, National Cancer Center Hospital, Tokyo, Japan
³⁸Division of Hematology, Jichi Medical University Saitama Medical Center, Saitama City, Japan

Uday Prakash Kulkarni, MD^1*, Sushil Selvarajan, MD, DM^1*, Fouzia NA, DNB, DM^1*, Sharon Lionel, MBBS, MD, DM^1*, Sukesh C Nair, DCP DNB MD FRCPA^2*, Poonkuzhali Balasubramanian, MSc, PhD¹, Thenmozhi Mani, PhD^3*, Aby Abraham, MD, DM^1*, Biju George, MD, DM¹ and Vikram Mathews, MD, DM¹

¹Department of Haematology, Christian Medical College, Vellore, India
²Department of Transfusion Medicine and Immunohaematology, Christian Medical College, Vellore, India
³Department of Biostatistics, Christian Medical College, Vellore, India

Jorge Labrador^1,2*, Josefina Serrano^3*, Laura Torres^4*, Evelyn Acuña-Cruz, MD^5*, Jose A. Perez-Simon, MD, PhD⁶, Maria Lopez-Pavia^7*, Gabriela Rodriguez Macias, MD^8*, Carmen Botella^9*, Carlos Rodriguez^10*, Pilar Martinez Sanchez, MD^11*, Maria Luz Amigo, MD^12*, Maria Victoria Cuevas^13*, Teresa Bernal del Castillo, MD^14*, María Carmen Montes^15*, Celina Benavente^16*, Juan Ignacio Rodriguez-Gutierrez^17*, Mar Tormo¹⁸, Raimundo García-Boyero^19*, Aurelio Lopez Martínez, MD^20*, Rafael Lluch Garcia, MD^21*, Jesús Lorenzo Algarra, MD^22*, Esperanza Lavilla^23*, David Martinez-Cuadron^24*, Miguel A. Sanz, MD^25,26 and Pau Montesinos, MD, PhD^27*

¹Facultad de Ciencias de la Salud, Universidad Isabel I, Burgos, Spain
²Hematology Department, Research Unit, Hospital Universitario de Burgos, Burgos, Spain
³Hospital Universitario Reina Sofía, Córdoba, Spain
⁴Hospital Universitari I Politécnic La Fe, Valencia, Spain
⁵Hospital Universitario y Politécnico La Fe, Valencia, Spain
⁶Instituto de Biomedicina de Sevilla (IBiS), UGC-Hematología, Hospital Universitario Virgen del Rocío/ CSIC/ CIBERONC, Universidad de Sevilla, Sevilla, Spain
⁷Hospital General de Valencia, Valencia, Spain
⁸Hematology and hemotherapy department, Hospital General Universitario Gregorio Marañón, Madrid, Spain
⁹Hospital General Universitario de Alicante, Alicante, Spain
¹⁰Hospital Universitario de Gran Canaria Doctor Negrín, Las Palmas de Gran Canaria, Spain
¹¹Clinical Hematology, Hospital Universitario 12 de Octubre, Madrid, Spain
¹²Hospital Universitario Morales Messeguer, Murcia, Spain
¹³Hospital Universitario de Burgos, Burgos, Spain
¹⁴Hospital Universitario Central de Asturias, Instituto Universitario (IUOPA), Instituto de investigación del Principado de Asturias (ISPA),, Oviedo, ESP
¹⁵Complejo Asistencial de Zamora, Zamora, Spain
¹⁶Hospital Clinico San Carlos. Madrid, Madrid, Spain
¹⁷Hospital Universitario Basurto, Bilbao, Spain
¹⁸Hospital Clinico Universitario Valencia, Valencia, Spain
¹⁹Hospital General Universitario de Castellón, Castellón de la Plana, Spain
²⁰Hospital Arnau de Vilanova, Lleida, Spain
²¹Hospital de La Ribera, Alzira, Spain
²²Hematology department, Complejo Hospitalario Universitario de Albacete, Albacete, Spain
²³Hospital Universitario Lucus Augusti, Lugo, Spain
²⁴Instituto de Investigación Sanitaria La Fe (IISLAFE), Hematology Department, Hospital Universitari i Politécnic-IIS La Fe, Valencia, Spain
²⁵Programa Español de Tratamientos en Hematologia, PETHEMA, Valencia, Spain
²⁶Hematology Department, Hospital Universitari i Politècnic La Fe, Valencia, Spain
²⁷Hospital Universitari i Politècnic La Fe, Instituto de Investigación Sanitaria La Fe (IISLAFE), Valencia, Spain

Rory M. Shallis, MD¹, Julian Weiss^1*, Eric S. Winer, MD², Talha Badar, MD³, Alok Swaroop^4*, Peter Doukas^4*, Emily Geramita, MD, PhD⁵, Henry Le^6*, Sonal Agarwal, PharmD^6*, Man Yee Merl^6*, Annie Im, MD⁷, Yasmin Abaza, MD⁸, Mark R. Litzow, MD⁹ and Nikolai A. Podoltsev, MD, PhD¹

¹Yale University School of Medicine, New Haven, CT
²Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
³Division of Hematology and Oncology, Mayo Clinic Florida, Jacksonville, FL
⁴Northwestern University, Chicago
⁵Division of Hematology-Oncology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA
⁶Department of Pharmacy Services, Smilow Cancer Hospital at Yale New Haven Health, New Haven
⁷Univ. of Pittsburgh Cancer Institute, Pittsburgh, PA
⁸Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL
⁹Division of Hematology, Mayo Clinic, Rochester, MN

Bart L. Scott, MD¹, Michael R. Savona, MD², Gail J. Roboz, MD³, Karen Seiter⁴, Daniel A. Pollyea, MD⁵, Irene S. DeGutis^6*, Pavel Kiselev^6*, Edward Yu, ScD^6*, Ali McBride⁶, Willem Heydendael, PhD^6* and Harry P. Erba, MD, PhD⁷

¹Fred Hutchinson Cancer Research Center, Seattle, WA
²Vanderbilt-Ingram Cancer Center, Nashville, TN
³Weill Cornell Medicine and New York-Presbyterian Hospital, New York, NY
⁴New York Medical College, Valhalla, NY
⁵University of Colorado, Aurora, CO
⁶Bristol Myers Squibb, Princeton, NJ
⁷Duke University, Durham, NC

Margaret Li Krackeler, MD¹, Benjamin Moskoff, PharmD^2*, Tamer Othman, MD^3*, Tali Azenkot, MD^1*, Ryan J. Beechinor, PharmD^2*, Aaron S Rosenberg, MD⁴, Naseem S Esteghamat, MD⁴, Rasmus T Hoeg, MD^4*, Joseph M Tuscano, MD⁴ and Brian A. Jonas, MD, PhD⁵

¹Department of Internal Medicine, University of California Davis School of Medicine, Sacramento, CA
²Pharmacy Department, University of California Davis School of Medicine, Sacramento, CA
³University of California Davis Comprehensive Cancer Center, Sacramento, CA
⁴Department of Internal Medicine, Division of Cellular Therapy, Bone Marrow Transplantation and Malignant Hematology, University of California Davis School of Medicine, Sacramento, CA
⁵Department of Internal Medicine, Division of Malignant Hematology, Transplantation and Cellular Therapy, University of California Davis School of Medicine, Sacramento, CA

Zachery Clint Branham, DO^1*, Chijioke Okereke, MD^2*, Mahran Shoukier, MD^3*, Danielle Bradshaw, MD^4*, Ravindra Kolhe, MD, PhD^5*, Anand P. Jillella, MD⁴ and Vamsi K. Kota, MD⁴

¹Augusta University, Augusta, GA
²Department of Internal Medicine, Medical College of Georgia at Augusta University, Augusta, GA
³Georgia Cancer Center, Augusta University, Augusta, GA
⁴Division of Hematology/Oncology, Georgia Cancer Center at Augusta University, Augusta, GA
⁵Department of Pathology, Augusta University, Augusta, GA

Fabio Guolo, MD^1,2*, Paola Minetto, MD, PhD¹, Carola Riva, MD^1*, Chiara Vernarecci, MD^1*, Monica Passannante, MD^1*, Francesca Parodi^3*, Michela Frello, MD^1*, Elena Maio^3*, Beatrice Ferro^3*, Maria Chies^3*, Maurizio Miglino, MD, PhD^4*, Elisabetta Tedone^5*, Nicoletta Colombo, PhD^5*, Enrico Carminati^1*, Clara Nurra^1*, Francesco Puglisi^3*, Antonia Cagnetta, MD^1*, Michele Cea^1* and Roberto Massimo Lemoli, MD^1,6

¹Clinic of Hematology, Department of Internal Medicine (DiMI), IRCCS Ospedale Policlinico San Martino, Genova, Italy
²Clinic of Hematology, Department of Internal Medicine (DiMI), Policlinico San Martino, IRCCS per l’Oncologia, University of Genoa, Genoa, Italy
³University of Genoa, Genoa, Italy
⁴IRCCS San Martino Hospital, Genoa, Italy
⁵Clinical Flow Cytometry Unit, IRCCS Ospedale Policlinico San Martino, Genova, Italy
⁶Clinic of Hematology, Department of Internal Medicine (DiMI),IRCCS per l’Oncologia, University of Genoa, Genoa, Italy

Anna Moseley^1*, Boris Freidlin, PHD^2*, Rory M. Shallis, MD³, Amer M. Zeidan, MD⁴, David A. Sallman, MD⁵, Richard F. Little, MD, MPH⁶, Harry P. Erba, MD, PhD⁷, Michael L. Leblanc, PhD^8* and Megan Othus, PhD⁹

¹SWOG Statistical Center, Fred Hutchinson Cancer Center, Seattle, WA
²Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD
³Yale University School of Medicine, New Haven, CT
⁴Department of Internal Medicine, Yale School of Medicine and Yale Cancer Center, New Haven, CT
⁵Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL
⁶National Cancer Institute, Washington, DC
⁷Leukemia Program, Duke University Medical Center, Durham, NC
⁸SWOG Statistical Center, Fred Hutchinson Cancer Research Center, Seattle, WA
⁹Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA

Brandon J Kale, MD^1*, Grace Hwang, PharmD^2*, Purnima Sravanti Teegavarapu, MD^3,4,5, Martha P. Mims, MD, PhD^3,4,5 and Gustavo Rivero, MD^3,4,5

¹Department of Medicine, Baylor College of Medicine, Houston, TX
²Department of Pharmacy, Baylor St.Luke's Medical Center, Houston, TX
³Department of Hematology/Oncology, Baylor St Luke's Medical Center, Houston, TX
⁴Department of Medicine, Hematology/Oncology, Baylor College of Medicine, Houston, TX
⁵Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine, Houston, TX

Cristobal Augusto Frutos Ortiz, MD^1*, Lidiane Andino^2*, Alfredo Reinaldo Quiroz, MD^1*, Dietger Niederwieser, MD³, Maria Elvira Enciso, MD^4*, Aline Nicole Paats, MD^4* and Victor Salinas^5*

¹Department of Hematology, Instituto de Prevision Social, Asuncion, Paraguay
²Hematology Service, Hospital Central del Instituto de Previsión Social, Asuncion, Paraguay
³University of Leipzig, Leipzig, Germany
⁴Instituto de Prevision Social, Asuncion, Paraguay
⁵Sociedad Paraguaya de Hematología y Hemoterapia, Asuncion, Paraguay

Shai Shimony, MD^1,2*, Geoffrey G Fell^3*, Evan C. Chen, MD², Harrison Tsai^4*, Martha Wadleigh, MD², Eric S. Winer, MD², Jacqueline S. Garcia, MD², Marlise R. Luskin, MD², Maximilian F. Stahl, MD², Donna S. Neuberg, ScD³, Daniel J DeAngelo, MD, PhD⁵, R. Coleman Lindsley⁶ and Richard M. Stone, MD⁵

¹Rabin Medical Center and Faculty of Medicine, Tel Aviv University, Petah Tikva, ISR
²Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
³Department of Data Science, Dana-Farber Cancer Institute, Boston, MA
⁴Department of Pathology Boston Children’s Hospital, Boston, MA
⁵Center for Leukemia, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
⁶Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA

Clement Dove Okello, MD^1*, Soheil Meshinchi, M.D., Ph.D.², Katherine Tarlock, MD³, Edus H. Warren, MD, PhD^4,5,6, Andrea M. H. Towlerton^7*, Henry Ddungu¹, Yusuf Mulumba^1*, Fadhil Geriga, MBChB^1*, Jackson Orem, MBChB, MMed, PhD¹ and Joyce K. Balagadde^1*

¹Uganda Cancer Institute, Kampala, Uganda
²Fred Hutchinson Cancer Center, Seattle, WA
³Department of Pediatrics, University of Washington, Seattle, WA
⁴Division of Hematology and Medical Oncology, University of Washington, Seattle, WA
⁵Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
⁶Seattle Cancer Care Alliance, Seattle, WA
⁷Fred Hutchinson Cancer Research Center, Seattle, WA

Khaldun Obeidat^1*, Ekrem Turk, MD^1*, Vaishali Deenadayalan, MD¹, Rafaella Litvin, MD^1*, Maryam Zia^1,2 and Shelby D. Rifkin, MD¹

¹John H Stroger Jr Hospital of Cook County, Chicago, IL
²Division of Hematology/Oncology, University of Illinois College of Medicine At Chicago, Chicago, IL

Robert Zeiser, MD^1,2, Christoph Schmid, MD^3*, Gheath Alatrash, PhD, DO^4,5, Ron Ram, MD^6*, Yuan Wu^7*, Hans-Jochen Jochen Weber, PhD^8*, Stephanie Grzesiak^9*, Lamis K. Eldjerou, MD¹⁰ and Charles Craddock¹¹

¹University Medical Center Freiburg, Freiburg, Germany
²Department of Medicine I, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg, Germany
³Department of Hematology and Oncology / Stem Cell Transplantation, Augsburg University Hospital and Medical Faculty, Augsburg, Germany
⁴Department of Hematopoietic Biology & Malignancy, The University of Texas MD Anderson Cancer Center, Pearland, TX
⁵Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
⁶BMT Unit, Tel Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⁷Oncology Analytics, Novartis Pharmaceuticals, Basel, Switzerland
⁸Novartis Pharma AG, Basel, Switzerland
⁹Novartis Pharmaceuticals, Basel, Switzerland
¹⁰Novartis Pharmaceuticals Corporation, East Hanover, NJ
¹¹Department of Haematology, University Hospital Birmingham NHS Trust, Queen Elizabeth Medical Centre, Birmingham, ENG, United Kingdom

Volkan Karakuş, Assoc. Prof^1*, Omur Gokmen Sevindik, Prof², Aylin Karatas^3*, Emel Merve Yenihayat, M.D^4*, Merve Gokcen Polat, M.D^4*, Serhat Çelik, M.D^5*, Ibrahim Ethem Pinar, M.D^6*, Ali Dogan, M.D^7*, Idris İnce, M.D^8*, Umit Yavuz Malkan^9*, Utku Iltar, M.D^10*, Demircan Özdalcı Ozdalcı^11*, Özgür Mehtap, MD^12*, Ramazan Erdem, M.D^13*, Murat Kacmaz, M.D^14*, Fatma Aykas, M.D^15*, Berna Ozturk, M.D^16*, Burak Deveci, MD^17*, Aydan Akdeniz, M.D^18*, Hale Bulbul, M.D^19*, Sureyya Yigit Kaya, MD^20*, Ferda Can, M.D^21*, Zeynep Guven, MD^22*, Ceyda Aslan, M.D^23*, Muzaffer Keklik, MD^24*, Fahir Ozkalemkas, MD^25*, Hakan Goker, MD, PROF^26* and İnci Alacacıoğlu, M.D.^27*

¹Department of Hematology, Antalya Research and Training Hospital, Antalya, Turkey
²Department of Hematology, Medipol University International School of Medicine, Istanbul, Turkey
³Dokuz Eylul University, Faculty of Medicine, Izmir, TUR
⁴Kocaeli University Hospital, Kocaeli, Turkey
⁵Erciyes University, Faculty of Medicine, Hematology Department, Kayseri, Turkey
⁶Bursa Uludag University Hospital, Bursa, Turkey
⁷Van Yüzüncü Yıl University Hospital, van, Turkey
⁸Gaziantep Dr. Ersin Arslan Training and Research Hospital, Gaziantep, Turkey
⁹Hacettepe University Hospitals, Ankara, Turkey
¹⁰Akdeniz University Health Practice and Research Hospital, Antalya, Turkey
¹¹Suleyman Demirel University Research and Application Hospital, Isparta, Turkey
¹²Department of Hematology, Kocaeli University, Kocaeli, Turkey
¹³Ministry of Health Antalya Provincial Health Directorate Antalya Training and Research Hospital, Antalya, Turkey
¹⁴Hatay Mustafa Kemal University, Hatay, Turkey
¹⁵Republic of Turkey Ministry of Health Antalya Provincial Health Directorate Antalya Training and Research Hospital, Antalya, Turkey
¹⁶Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey
¹⁷Medstar Hospital, Antalya, Turkey
¹⁸Mersin University, Mersin, Turkey
¹⁹HEALTH SCIENCES UNIVERSITY İZMİR TEPECİK EDUCATION AND RESEARCH HOSPITAL, Izmır, Turkey
²⁰Manisa Cıty Hospital, Manisa, Turkey
²¹Ankara City Hospital, Ankara, Turkey
²²Nigde Training and Research Hospital, Nigde, Turkey
²³Kocaeli Derince Training and Research Hospital, Kocaeli, Turkey
²⁴Erciyes University, Kayseri, TUR
²⁵Hematology, Uludag University Faculty of Medicine, Bursa, Turkey
²⁶Department of Internal Medicine, Division of Hematology, Hacettepe University, Ankara, AE, Turkey
²⁷Department of Internal Medicine, Division of Hematology, Dokuz Eylül University School of Medicine, İzmir, Turkey

Michal Jakub Kubiak, MD¹, Anand P. Jillella, MD², Danielle Bradshaw, MD^2*, Natasha M. Savage, MD³, Ravindra Kolhe, MD, PhD^4*, Locke J. Bryan, MD² and Vamsi K. Kota, MD²

¹Augusta University, Augusta, GA
²Division of Hematology/Oncology, Georgia Cancer Center at Augusta University, Augusta, GA
³Department of Pathology, Augusta University Medical Center, Augusta, GA
⁴Department of Pathology, Augusta University, Augusta, GA

Naoki Miyashita, M.D.^1*, Masahiro Onozawa, M.D., Ph.D.¹, Shota Yoshida, MD^1*, Hiroyuki Kimura, M.D.^1*, Shogo Takahashi, M.D.^1*, Shota Yokoyama^1*, Toshihiro Matsukawa, M.D., Ph.D.^1*, Shinsuke Hirabayashi, M.D, Ph.D.^2*, Shinichi Fujisawa^3*, Akio Mori, MD, PhD⁴, Shuichi Ota, M.D., Ph.D.⁵, Yasutaka Kakinoki, M.D., Ph.D.^6*, Yutaka Tsutsumi, M.D., Ph.D.^7*, Satoshi Yamamoto, M.D., Ph.D.^8*, Takuto Miyagishima, M.D., Ph.D.^9*, Takahiro Nagashima, M.D., Ph.D.^10*, Makoto Ibata, M.D., Ph.D.^11*, Hajime Kobayashi, M.D, Ph.D.^12*, Yoshihito Haseyama, M.D, Ph.D.^13*, Katsuya Fujimoto, M.D, Ph.D.^14*, Toshimichi Ishihara, M.D., Ph.D.^15*, Hajime Sakai, M.D, Ph.D.¹⁶, Takeshi Kondo⁴ and Takanori Teshima, M.D., Ph.D.^1,3

¹Department of Hematology, Hokkaido University Faculty of Medicine, Sapporo, Japan
²Department of Pediatrics, Hokkaido University, Graduate school of Medicine, Sapporo, Japan
³Division of Laboratory and Transfusion Medicine, Hokkaido University Hospital, Sapporo, Japan
⁴Blood Disorders Center, Aiiku Hospital, Sapporo, Japan
⁵Department of Hematology, Sapporo Hokuyu Hospital, Sapporo, Japan
⁶Department of Hematology, Asahikawa City Hospital, Asahikawa, Japan
⁷Department of Hematology, Hakodate Municipal Hospital, Hakodate, Japan
⁸Department of Hematology, Sapporo City General Hospital, Sapporo, Japan
⁹Department of Hematology, Kushiro Rosai Hospital, Kushiro, Japan
¹⁰Department of Internal Medicine, Kitami Red Cross Hospital, Kitami, Japan
¹¹Department of Hematology, Sapporo-Kosei General Hospital, Sapporo, Japan
¹²Department of Hematology, Obihiro Kosei Hospital, Obhiro, Japan
¹³Department of Hematology, Tonan Hospital, Sapporo, Japan
¹⁴Department of Hematology, National Hospital Organization Hokkaido Cancer Center, Sapporo, Japan
¹⁵Department of Hematology, Kin-ikyo Chuo Hospital, Sapporo, Japan
¹⁶Department of Hematology, Teine Keijinkai Hospital, Sapporo, Japan

Elliot C. Smith, MD^1,2*, Eshetu G. Atenafu, M.Sc., P.Stat^3*, Aniket Bankar, MBBS, MD, DM¹, Steven M. Chan, MD, PhD¹, Marta B. Davidson, MD, PhD¹, Vikas Gupta, MD, FRCP, FRCPath^1,2, Mark D. Minden, MD, PhD^1,2, Guillaume Richard-Carpentier, MD, FRCPC¹, Aaron D. Schimmer, MD, PhD^2,4, Andre C. Schuh, MD^2,4, Hassan Sibai, MBBS, MD^2,5*, Karen Yee, MD^2,5 and Dawn Maze, MD, FRCPC, MSc^1,2

¹Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
²Department of Medicine, University of Toronto, Toronto, ON, Canada
³Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
⁴Division of Medical Oncology and Hematology, University Health Network, Toronto, ON, Canada
⁵Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada

Tareq Abuasab, MD¹, Srdan Verstovsek, MD, PhD¹, Gautam Borthakur, MD¹, Rashmi Kanagal-Shamanna, MD², Keyur Patel, MD, PhD^2*, Koichi Takahashi, MD, PhD³, Lucia Masarova, MD¹, Prithviraj Bose, MD⁴, John Villarreal^1*, Sherry A. Pierce, BSN, BA^1*, Guillermo Montalban-Bravo, MD¹, Guillermo Garcia-Manero, MD⁵, Nicholas Short, MD¹, Courtney D. DiNardo, MD, MSCE¹, Naval Daver, MD¹, Farhad Ravandi, MD¹, Hagop Kantarjian, MD¹ and Musa Yilmaz, MD¹

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX
⁴The University of Texas MD Anderson Cancer Center, Houston, TX
⁵Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX

Jiale Ma^1,2*, Chunhua Song, MD，PhD^3,4 and Zheng Ge, MD, PhD¹

¹Department of Hematology, Zhongda Hospital, School of Medicine, Institute of Hematology, Southeast University, Nanjing, China
²Department of Hematology,Xuzhou Central Hospital, Xuzhou, China
³Hershey Medical Center, Pennsylvania State University Medical College, Hershey
⁴Division of Hematology, The Ohio State University Wexner Medical Center, the James Cancer Hospital, Columbus

Omer H Jamy, MD¹, Kendall Diebold, CRNP^2*, Kimo Bachiashvili, MD³, Sravanti Rangaraju, MBBS⁴, Pankit Vachhani, MD^5*, Kelly N. Godby, MD^6*, Donna Salzman, MD⁷ and Ravi Bhatia, MD¹

¹Division of Hematology and Oncology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL
²University of Alabama at Birmingham, Birmingham
³O’ Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL
⁴University of Alabama at Birmingham, Birmingham, AL
⁵O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL
⁶Department of Medicine, Division of Hematology/Oncology, University of Alabama at Birmingham Hospital, Birmingham, AL
⁷Divison of Hematology/Oncology, University of Alabama at Birmingham, Birmingham, AL

Raffaele Palmieri, raffaele.f.palmieri@gmail.com^1*, Simona Iacobelli^2*, Giovangiacinto Paterno, MD^3*, Moretti Federico^4*, Elisa Buzzatti, MD^4*, Meddi Elisa^5*, Savi Arianna^4*, Gentiana Trotta^4*, Flavia Mallegni^4*, Maria Ilaria Del Principe, MD^6*, Luca Maurillo, MD^7*, Maria Teresa Voso, MD⁸, Adriano Venditti, MD⁹ and Francesco Buccisano, MD¹⁰

¹Università Tor Vergata - Fondazione Policlinico Tor Vergata, Roma, ITA
²Department of Biology, Centro Di Biostatistica E Bioinformatica Università Tor Vergata, Rome, Italy
³Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
⁴Ematologia Dipartimento di Biomedicina e Prevenzione, Università di Roma “Tor Vergata”, Rome, Italy
⁵Ematologia Dipartimento di Biomedicina e Prevenzione, Università di Roma “Tor Vergata, Rome, Italy
⁶Ematologia, Dipartimento di Biomedicina e Prevenzione, Università degli studi di Roma Tor Vergata, Roma, Italy
⁷Department of Onco-Hematology, Policlinico Tor Vergata, Rome, Rome, Italy
⁸Department of Biomedicine and Prevention, University of Rome “Tor Vergata”, Rome, Italy
⁹Hematology, Department of Biomedicine and Prevention, University Tor Vergata, Rome, Italy
¹⁰Hematology, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy

Alejandra Romero, MD^1*, Francisca Bass, MD^2*, Veronica Lizama, MD^3*, Christine Rojas^4*, Javier Diaz, MD^5*, Marisa Capurro, MD^6*, Yaima Gutierrez, MD^6*, Matias Sanchez, MD⁷, Natalia Aránguiz, MD^8*, Marcela Espinoza, MD^9*, Maria Carolina Guerra, MD^10*, Sebastian Hidalgo, MD^11*, Joaquín Jerez, MD^12*, Pilar León, MD^13*, Bernardita Rojas, MD^14*, Ernesto Castaño, MD^15*, Denis Suarez Munoz, MD^16*, Vivianne Torres, MD^17*, Monica Paulina Fuentes, MD^17*, Miguel Lopez, MD^18*, Rocío Osorio, MD^19*, Belkys Mercedes Linares, MD^20*, Robert Holloway Melo, MD^21*, Paola Aravena, MD^22*, Patricia Fardella, MD^23*, Felipe Ramirez, MD^24*, Constanza Flores, MD^24*, Maria Soledad Urquieta, MD^25*, David Martinez-Cuadron^26* and Pau Montesinos, PhD, MD^27,28*

¹Hospital Guillermo Grant Benavente, Concepción, Chile
²Hospital del Salvador, Santiago, Chile
³Hospital del Salvador, Santiago, Región Metropolitana, CHL
⁴Hospital Gustavo Fricke, Viña del Mar, Valparaíso, Chile
⁵Hospital Gustavo Fricke, Viña del Mar, CHL
⁶Hospital de Temuco, Temuco, Chile
⁷Clinica Alemana de Santiago, New York, NY
⁸Clinica Alemana, Santiago, Chile
⁹Clinica Dávila, Santiago, Chile
¹⁰Fundación Arturo López Pérez, SANTIAGO, CHL
¹¹Fundación Arturo López Pérez, Santiago, CHL
¹²Fundación Arturo López Pérez, Santiago, Chile
¹³Hospital Van Buren, Valparaiso, Chile
¹⁴Hospital Van Buren, Viña Del Mar, CHL
¹⁵Hospital Sótero del Río, Santiago, Chile
¹⁶Hospital Sotero Del Río, Santiago, CHL
¹⁷Hospital Base de Valdivia, Valdivia, Chile
¹⁸Hospital Universidad de Chile, Santiago, Chile
¹⁹Hospital de Arica, Arica, Chile
²⁰Hospital DIPRECA, Santiago, Metropolitana DE Santiago, CHL
²¹Hospital Dipreca, SANTIAGO, CHL
²²Clinica Las Condes, SANTIAGO, CHL
²³Clinica Las Condes, Santiago, Chile
²⁴Hospital San Juan de Dios, La Serena, Chile
²⁵Hospital Naval, Viña del Mar, Chile
²⁶Hospital Universitario La Fe, Valencia, Valencia, Spain
²⁷Hospital Politecnico Universitario La Fe, Valencia, Spain, Spain
²⁸Hematology Department, Hospital Universitario y Politécnico La Fe, Valencia, Spain