Kadriye Nehir Cosgun, PhD^1*, Wei Liu^2*, Mark E. Robinson, PhD^1*, David Fonseca Arce^1*, Jennifer VanOudenhove, PhD^3*, Alberto Bigogno^1*, Richard Flavell, PhD^4*, Stephanie Halene, MD² and Markus Müschen, MD¹

¹Center of Molecular and Cellular Oncology and Department of Immunobiology, Yale University, New Haven, CT
²Section of Hematology, Department of Internal Medicine and Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, CT
³Section of Hematology, Department of Internal Medicine, Yale University School of Medicine and Yale Cancer Center, New Haven, CT
⁴Department of Immunobiology, Yale University School of Medicine, New Haven, CT

Ethan Whipp, MSc^1,2*, Zachary A Hing, MD, PhD^3,4, Janek S. Walker, PhD⁵, Steven Sher^6*, Casey B. Cempre, B.S.^5*, Fiona Brown, BS⁷, Claudio Agostinelli, MD^8,9*, Stefano A Pileri^10,11,12, Katie Williams, MS^5*, Larry Beaver, BS^5*, Alexander Pan, BS^13*, Charles T. Gregory^5,14*, Pearlly S. Yan, PhD^15*, Peggy Scherle, PhD¹⁶, Min Wang^17*, Kris Vaddi, PhD^16,17,18, Selina Chen-Kiang, PhD^19,20,21,22, Jennifer A. Woyach, MD^5,7,23, James S. Blachly, MD^5,24,25, Lapo Alinari, MD, PhD⁷, Yiping Yang, MD, PhD²⁶, Robert A. Baiocchi, MD, PhD^5,14, Bradley W Blaser, MD, PhD^5,27 and Rosa Lapalombella, PhD^28,29

¹Division of Hematology, Ohio State University, Columbus, OH
²Division of Pharmaceutics & Pharmacology, Ohio State University - College of Pharmacy, Columbus, OH
³Division of Hematology, Department of Internal Medicine, The Ohio State University, Wexner Medical Center, Columbus, OH
⁴Medical Scientist Training Program, The Ohio State University, Wexner Medical Center, Columbus, OH
⁵Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH
⁶Division of Hematology, Department of Internal Medicine, THE OHIO STATE UNIVERSITY, COLUMBUS, OH
⁷Department of Internal Medicine, Division of Hematology, College of Medicine, The Ohio State University, Columbus, OH
⁸Haematopathology Unit, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, ITA
⁹Haematopathology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna and Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy
¹⁰Hematopathology Division, IEO Istituto Europeo di Oncologia IRCCS, Milano, Italy
¹¹University of Bologna, Milan, Italy
¹²European Instute of Oncology, Milan, Italy
¹³The Ohio State University, Columbus, OH
¹⁴Comprehensive Cancer Center, The Ohio State University, Columbus, OH
¹⁵Genomic Shared Resource, The Ohio State University, Columbus, OH
¹⁶Research and Development, Prelude Therapeutics, Wilmington, DE
¹⁷Prelude Therapeutics, Wilmington, DE
¹⁸Incyte Corporation, Wilmington, DE
¹⁹Weil Cornell Medicine, Cornell University, New York, NY
²⁰Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY
²¹Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY
²²Graduate Program in Immunology and Microbial Pathogenesis, Weill Cornell Medicine, New York, NY
²³Division of Hematology, Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, OH
²⁴Department of Biomedical Informatics, The Ohio State University, Columbus, OH
²⁵Division of Hematology, The Ohio State University Comprehensive Cancer Center, Columbus, OH
²⁶Department of Internal Medicine, Division of Hematology, The Ohio State University, Columbus, OH
²⁷The Ohio State University Comprehensive Cancer Center, Division of Hematology, Columbus, OH
²⁸The Ohio State University Comprehensive Cancer Center, Columbus, OH
²⁹Division of Hematology, Department of Medicine, The Ohio State University, Columbus, OH

Luz Yurany Moreno Rueda, Ph.D., M.Sc.^1*, Dean Bryant, PhD^1*, William J Tapper, PhD^2*, Nicky Weston-Bell, PhD, BSc^1*, David C Wedge, PhD^3*, Naser Ansari-Pour, PhD^4* and Surinder S Sahota, PhD^1*

¹Tumour Immunogenetics Group, Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
²Genetic Epidemiology and Genomic Informatics Group, Human Genetics, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
³Manchester Cancer Research Centre, University of Manchester, Manchester, United Kingdom
⁴MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom

Triantafyllia Brozou, MD^1*, Rabea Wagener, PhD^2*, Danielle Brandes^3*, Ute Fischer, PhD^2* and Arndt Borkhardt, MD⁴

¹Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich-Heine-University and University Hospital Duesseldorf, Duesseldorf, Germany
²Department of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich Heine University, Medical Faculty, Duesseldorf, Germany
³Duesseldorf School of Oncology (DSO), Medical Faculty, Heinrich-Heine University, Duesseldorf, Germany
⁴Department of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich-Heine University Duesseldorf, Medical Faculty, Duesseldorf, Germany

Gabriela Cristina Segat, MSc^1*, Ann Chong Sun^1*, Alice C Zhu^2*, Marissa Foo^1*, Claudia V Barreto Rodriguez^1*, Rachel Wong^1*, Samuel Gusscott, PhD^1*, Martin Hirst, PhD^2* and Andrew P. Weng, MD³

¹Terry Fox Laboratory, BC Cancer, Vancouver, BC, Canada
²Canada’s Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC, Canada
³Terry Fox Laboratory, BC Cancer Agency, Vancouver, BC, Canada

Sakurako Suma, MD^1,2*, Manabu Fujisawa, MD, PhD^3*, Yoshiaki Abe, MD^1*, Yasuhito Suehara, MD, PhD^2,3*, Daisuke Kaji, MD, PhD^4*, Takeshi Sugio, MD^5*, Koji Kato, MD, PhD⁶, Koichi Akashi, MD, PhD⁷, Kosei Matsue, MD, PhD⁸, Naoya Nakamura, MD, PhD^9*, Ayako Suzuki, Ph.D.^10*, Yutaka Suzuki, Ph.D.^11*, Shigeru Chiba, MD, PhD^2,3 and Mamiko Sakata-Yanagimoto, MD, PhD^2,3,12*

¹Department of Hematology, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan
²Department of Hematology, University of Tsukuba Hospital, Tsukuba, Japan
³Department of Hematology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan
⁴Department of Hematology, Toranomon Hospital, Tokyo, Japan
⁵Department of Medicine, Division of Oncology, Stanford University, Stanford, CT
⁶Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Science, Fukuoka, Japan
⁷Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
⁸Department of Hematology/Oncology, Kameda Medical Center, Kamogawa, Japan
⁹Department of Pathology, Tokai University School of Medicine, Isehara, Japan
¹⁰Department of Computational Biology and Medical Sciences, The University of Tokyo, Kashiwa, Japan
¹¹Laboratory of Systems Genomics, Department of Computational Biology and Medical Sciences, The University of Tokyo, Tokyo, Japan
¹²Division of Advanced Hemato-Oncology, Transborder Medical Research Center, University of Tsukuba, Tsukuba, Japan

Wangisa M.B. Dunuwille, PhD, BVSc.^1*, William Casey Wilson, PhD^2*, Nancy Issa, MD^1*, Won Kyun Koh, PhD¹, Wentao Han^3* and Grant A Challen, PhD¹

¹Division of Oncology, Washington University School of Medicine, St. Louis, MO
²Scientific research laboratory, Arch Oncology, St. Louis, MO
³Division of Oncology, Washington University School of Medicine, Saint Louis, MO

Lai N. Chan, PhD¹, Mark E. Robinson, PhD^1*, Kadriye Nehir Cosgun, PhD^1*, Xiaohui Yu^1*, Etienne Leveille, MD¹, Huimin Geng, PhD² and Markus Müschen, MD¹

¹Center of Molecular and Cellular Oncology and Department of Immunobiology, Yale University, New Haven, CT
²Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA

Pauline Schneider^1*, Susan T.C.J.M. Arentsen-Peters, BSc^1*, Nicholas T. Crump^2*, Alastair Smith^2*, Rico Hagelaar, MSc^1,3*, Fabienne R.S. Adriaanse, MSc^1*, Romy S. Bos^1*, Kirsten S. Vrenken, PhD^1*, Dedeke rockx-Brouwer^1*, Ziqin Tang^1,3*, Wilbert P. Vermeij^1,3*, Anja De Jong^4*, Bianca Koopmans, BSc^1*, M.Emmy M. Dolman^1*, Thomas A. Milne², Rob Pieters, Prof. MD. PhD¹ and Ronald W. Stam, PhD^1*

¹Princess Máxima Center for Pediatric Oncology, Utrecht, Netherlands
²MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, NIHR Oxford Biomedical Research Centre Haematology Theme, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom
³Oncode Institute, Utrecht, Netherlands
⁴Dutch Oncology Group, Utrecht, NLD

Nguyet Minh Hoang, BS¹, Yunxia Liu, PhD^1* and Lixin Rui, PhD²

¹Department of Medicine and Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, WI
²Department of Medicine and Carbone Cancer Center, University of Wisconsin School of Medicine, Madison, WI

B. Hilda Ye, PhD¹, Elaine Chung, PhD^1*, Xiaoxin Ren, Ph.D.^2*, Kith Pradhan, PhD^3*, Yanhua Wang, MD, PhD^4*, Advaitha Madireddy, PhD⁵, Xingxing Zang, PhD^6*, Murali Janakiram, MD, MS⁷, R. Alejandro Sica, MD⁸ and Amit Verma, MD⁹

¹Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY
²Albert Einstein College of Medicine, Bronx, NY
³Department of Epidemiology & Population Health, Montefiore Medical Center, Bronx, NY
⁴Department of Pathology, Montefiore Medical Center Center for Cancer Care, Bronx, NY
⁵Rutgers Cancer Institute of New Jersey, New Brunswick, NJ
⁶Montefiore Medical Center Center for Cancer Care, Bronx, NY
⁷Department of Hematology and Medical Oncology, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY
⁸Hematology/Oncology, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY
⁹Department of Oncology, Montefiore Medical Center/ Albert Einstein College of Medicine, Bronx, NY

Kevin O'Connor, MSc^1*, Kensei Kishimoto^1*, Irena Kuzma^1*, Kelsey Wagner^1*, Jonathan Selway^1*, Kayleigh M Gallagher, PhD¹, Justine E. Roderick, PhD^1*, David J. Curtis, MBBS, PhD², Cedric Tremblay, PhD^3* and Michelle A Kelliher, PhD¹

¹Department of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA
²Australian Centre for Blood Diseases, Monash University, Melbourne, VIC, Australia
³Australian Centre for Blood Diseases, Monash University, Melbourne, Australia

Haopeng Yang, PhD^1*, Wenchao Zhang, PhD^1*, Vida Ravanmehr^2*, Jared Henderson, PhD^3*, Qing Deng, PhD^3*, Felipe Samaniego, MD⁴, Fernando Rodrigues-Lima^5* and Michael R. Green, PhD⁶

¹Department of Lymphoma & Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX
²University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Lymphoma & Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
⁴Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
⁵University of Paris, Paris, France
⁶Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Friendswood, TX

Guy Jacques LeClerc, PhD, BSc^1*, Helena Gomes Dos Santos, PhD^2*, Guangyan Sun, PhD^3*, Ramin Shiekhattar, PhD^4* and Julio C Barredo, MD^1,5,6,7

¹Pediatrics, University of Miami Miller School of Medicine, Miami, FL
²Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL
³Department of Pediatrics, University of Miami Miller School of Medicine, Miami, FL
⁴Department of Human Genetics, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL
⁵Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL
⁶Medicine, University of Miami Miller School of Medicine, Miami, FL
⁷Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL

Christoph Weigel, PhD^1,2*, Esko Kautto^1,2, Elshafa H. Ahmed, DVM, PhD^3,4, Yue-Zhong Wu^1,2*, Charles T. Gregory^1,2*, Ada C. Cleary^1,2*, Sarah Y. Schlotter^1,2, Eric Brooks, BS^1,2*, Mark Lustberg^5*, Robert A. Baiocchi, MD, PhD^1,2, James S. Blachly, MD^1,2,6 and Christopher C. Oakes, PhD^2,6,7

¹Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH
²Comprehensive Cancer Center, The Ohio State University, Columbus, OH
³Department of Internal Medicine, Division of Hematology, College of Medicine, The Ohio State University, Columbus, OH
⁴Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH
⁵Division of Infectious Diseases, Yale School of Medicine, New Haven, CT
⁶Department of Biomedical Informatics, The Ohio State University, Columbus, OH
⁷Clara D. Bloomfield Center for Leukemia Outcomes Research, The Ohio State University Comprehensive Cancer Center, Columbus