John McClatchy^*, Ruslan Strongantsev, PhD^*, Emily Wolfe, PhD^*, Joseph Estabrook, MS^*, Hsin-Yun Lin, BSc, Mona M.Hosseini, BSc^*, Hisham Mohamed, PhD^* and Anupriya Agarwal, PhD

Oregon Health and Science University, Portland, OR

Fernanda Gutierrez-Rodrigues, PhD¹, Adrianna I. Jones^2*, Kristina Wells^2*, Dalton Hironaka, BA^3*, Cameron Rankin^2*, Keith A Sikora, MD^2*, Kaitlin Quinn^2*, Marcela Ferrada, MD^4*, Bhavisha A. Patel, MD³, Peter C. Grayson, MD, Msc^4* and Neal S. Young, MD⁵

¹Hematology Branch, National Heart, Lung, and Blood Institute, National Institute of Health, Bethesda, MD
²Systemic Autoimmunity Branch, National Institutes of Arthritis, Musculoskeletal, and Skin Diseases, Bethesda, MD
³Hematology Branch, National Heart, Lung, and Blood Institute, Bethesda, MD
⁴Vasculitis Translational Research Program, National Institute of Arthritis, Musculoskeletal, and Skin Diseases. National Institutes of Health, Bethesda, MD
⁵Hematology Branch, National Heart, Lung, and Blood Institute. National Institutes of Health, Bethesda, MD

Constance Baer, PhD, Manja Meggendorfer, PhD, Wolfgang Kern, MD, Claudia Haferlach, MD, Torsten Haferlach, MD and Gregor Hoermann, MD, PhD

MLL Munich Leukemia Laboratory, Munich, Germany

Ismail Can, PhD^1,2,3,4, Reona Leo Sakemura, MD, PhD^1,4,5, Claudia Manriquez-Roman^1,3,4,6, Olivia Sirpilla, BS^1,3,4,7, Carli M. Stewart, BS^1,3,4,7, Kun Yun^1,3,4,6, Michelle J. Cox, Ph.D.^1,4,8, Truc Huynh^4*, James H. Girsch^1,3,4,6*, Ekene J. Ogbodo, Ph.D.^1,4*, Lionel A. Kankeu Fonkoua, M.D.^1,4,9, Mehrdad Hefazi, M.D.⁴, Michael W. Ruff, M.D.^4,9,10*, Justin C. Boysen^1*, Elizabeth L. Siegler, Ph.D.^1,4*, Atakan Ekiz, Ph.D.^11*, Saad S. Kenderian, MD^1,4,6,12,13 and Neil E. Kay, MD^12,13,14

¹Division of Hematology, Mayo Clinic, Rochester, MN
²Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN
³Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN
⁴T Cell Engineering, Mayo Clinic, Rochester, MN
⁵Mayo Clinic, Rochester, MN
⁶Department of Molecular Medicine, Mayo Clinic, Rochester, MN
⁷Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN
⁸Bioinformatics and Computational Biology, University of Minnesota Graduate School, Minneapolis, MN
⁹Department of Oncology, Mayo Clinic, Rochester, MN
¹⁰Department of Neurology, Mayo Clinic, Rochester, MN
¹¹Molecular Biology and Genetics, Izmir Institute of Technology, Izmir, Turkey
¹²Department of Immunology, Mayo Clinic, Rochester, MN
¹³Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN
¹⁴CLL Research Consortium, La Jolla, CA

Pinkal Desai, MD, MPH¹, Mayumi Sugita, MD², Rachel Heise, MS^1*, Madison Thies^1*, Nuria Mencia Trinchant, PhD^1*, Cynthia Crispino, BS^1*, Sharmaine Griffith-Baker^1*, Rejxhis Prifti^1*, Ashwini Kumar^1*, Michael Samuel, MD^3*, Justin D. Kaner, MD⁴, Ellen Ritchie, MD³, Wendy Cozen, DO, MPH⁵, Michael S. Simon, MD MPH^6*, Gail J. Roboz, MD³ and Monica L. Guzman, PhD⁷

¹Weill Cornell Medicine, New York, NY
²Division of Hematology/Oncology, Weill Cornell Medical College, New York, NY
³Division of Hematology and Oncology, Weill Cornell Medicine and The New York-Presbyterian Hospital, New York, NY
⁴Department of Medicine, Division of Hematology and Medical Oncology, Leukemia Program, Weill-Cornell Medicine, Syosset, NY
⁵Division of Hematology/Oncology, Department of Medicine, University of California Irvine, Orange, CA
⁶Barbara Ann Karmanos Cancer Center, Detroit
⁷Division of Hematology and Oncology, Department of Medicine, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY

Darja Karpova, PhD^1,2, Hector Huerga Encabo^3*, Elisa Donato^2*, Iuliia Kotova^4*, Silvia Calderazzo^5*, Aino-Maija Leppä^2*, Panten Jasper^6*, Adriana Przybylla^7*, Erhard Seifried^8,9, Annette Kopp-Schneider^10*, Terrence N Wong, MD, PhD¹¹, Dominique Bonnet, PhD¹², Halvard Bonig, MD, PhD^13,14,15 and Andreas Trumpp, PhD^16,17

¹Department of Medicine, Division of Oncology, Washington University School of Medicine, Saint Louis, MO
²Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany
³Hematopoietic Stem Cell Laboratory, The Francis Crick Institute, London, United Kingdom
⁴European Molecular Biology Laboratory (EMBL), Hamburg, Germany
⁵Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany
⁶Division of Regulatory Genomics and Cancer Evolution / Division of Computational Genomics and Systems Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany
⁷German Cancer Research Center, Heidelberg, Germany
⁸Institute Frankfurt, German Red Cross Blood Service Baden Wurttemberg-Hessen, Frankfurt, Germany
⁹Institute Frankfurt, Baden-Württemberg-Hessen gGmbH Institut Frankfurt, Frankfurt am Main, Germany
¹⁰Division of Biostatistics, German Cancer Research Center, Heidelberg, Germany
¹¹Department of Medicine/Division of Hematology & Oncology, Michigan Medicine, Ann Arbor, MI
¹²Hematopoietic Stem Cell Lab, The Francis Crick Institute, London, United Kingdom
¹³German Red Cross Blood Centre and Institute for Transfusion Medicine and Immunohematology, Johann-Wolfgang-Goethe University, Hematopoietic Cell Research Group, Frankfurt, Germany
¹⁴School of Medicine, University of Washington, Seattle, WA
¹⁵Institute for Transfusion Medicine and Immunohematology, German Red Cross Blood Centre Baden-Wuerttemberg-Hessen, Frankfurt/M, Germany
¹⁶Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany
¹⁷Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany

David J. Curtis, MBBS, PhD¹, Nicholas C. Wong, BSc (Hons) PhD^2*, Anna Leichter, BSc^3*, Le T.P. Thao, PhD^4*, James Phung, BSc^4*, Andrew J Murphy, BSc PhD^5*, Moeen Riaz, BS PhD^4*, Robert Sebra, PhD^6*, Alexander G. Bick, MD, PhD^7*, John J. McNeil, MBBS PhD^4*, Rory Wolfe, PhD^4*, Robyn L. Woods, BSc (Hons) PhD^4*, Paul Lacaze, PhD^4*, Erica M. Wood, MBBS, FRACP, FRCPA⁸ and Zoe McQuilten, MBBS, PhD^9*

¹Australian Centre for Blood Diseases, Monash University, Melbourne, VIC, Australia
²Monash Bioinformatics Platform, Monash University, Melbourne, Australia
³Australian Centre for Blood Diseases, Monash University, Melbourne, Australia
⁴Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia
⁵Haematopoiesis and Leukocyte Biology, Baker Heart and Diabetes Institute, Melbourne, Australia
⁶Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY
⁷Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN
⁸Transfusion Research Unit, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia
⁹Transfusion Research Unit, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia

Jan Boegeholz, MD¹, Stefan K. Alig, MD², Brian Sworder, MD, PhD³, Joseph Schroers-Martin, MD⁴, Charles Macaulay, MSc, BA^5*, Alexander F. M. Craig, MD, MPhil⁶, Ulrich Duehrsen, MD⁷, Andreas Hüttmann, MD⁸, Jason Westin, MD⁹, Hua-Jay J. Cherng, MD¹⁰, David B. Miklos, MD, PhD¹¹, Matthew J Frank, MD, PhD¹², Maximilian Diehn, MD, PhD^13,14*, David M. Kurtz, MD, PhD⁴ and Ash A. Alizadeh, MD, PhD¹⁵

¹Divisions of Hematology & Oncology, Stanford University, Stanford, CA
²Department of Medicine, Divisions of Oncology and Hematology, Stanford University, Stanford, CA
³Department of Oncology and Hematology, Stanford University Medical Center, Stanford, CA
⁴Divisions of Oncology and Hematology, Department of Medicine, Stanford University School of Medicine, Stanford, CA
⁵Divions of Oncology and Hematology, Stanford University, Stanford, CA
⁶Department of Medicine, Division of Oncology, Stanford University Medical Center, Stanford, CA
⁷Department of Hematology, Universitatsklinikum Essen, Essen, Germany
⁸Department of Hematology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, NRW, Germany
⁹The University of Texas MD Anderson Cancer Center, Houston, TX
¹⁰Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, TX
¹¹Division of Blood and Marrow Transplantation, Department of Medicine, Stanford University Medical Center, Stanford, CA
¹²Division of Blood and Marrow Transplantation and Cellular Therapy, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA
¹³Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA
¹⁴Stanford Cancer Institute, Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA
¹⁵Divisions of Oncology and Hematology, Department of Medicine, Stanford University School of Medicine, San Mateo, CA

Toby Thomas, B.S.^1*, Yuanyuan Ji, Ph.D.^1*, Fatma Kalkan, M.D.^2*, Albert Son, B.S.^3*, Ambarish Pandey, M.D.^2*, Vinayak Subramanian, M.D.^2*, Naveen Premnath, M.D.^4*, Michalis Agathocleous, PhD⁵, Qing Ding^6*, Alexander G. Bick, MD, PhD^7*, Benjamin Kroger, BS^1*, Dan Tong, M.D., Ph.D.^8* and Stephen S. Chung, MD¹

¹Division of Hematology and Oncology, Department of Internal Medicine, Children's Research Institute, University of Texas Southwestern, Dallas, TX
²Division of Cardiology, Department of Internal Medicine, University of Texas Southwestern, Dallas, TX
³Division of Hematology/Oncology, Department of Internal Medicine, University of Texas Southwestern, Dallas, TX
⁴Division of Hematology and Oncology, Department of Internal Medicine, University of Texas Southwestern, Dallas, TX
⁵Children's Research Institute, UT Southwestern, Dallas, TX
⁶Children’s Research Institute, University of Texas Southwestern, Dallas, TX
⁷Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN
⁸Division of Cardiology, Department of Internal Medicine, Dallas, TX

Teiko Kawahigashi, MD, PhD^1*, Shoya Iwanami^2*, Shingo Iwami^2* and Satoshi Yamazaki, PhD^3*

¹Stem Cell Therapy, University of Tsukuba, Yamato, Japan
²Nagoya University, Nagoya, Japan
³Department of Hematology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan

Chelsee Greer, DO^1*, Benjamin Kroger, BS^2*, Stephen S. Chung, MD³ and Kathryn Dickerson, MD, MS⁴

¹Pediatrics, UT Southwestern Medical Center, Dallas, TX
²Division of Hematology and Oncology, Department of Internal Medicine, Children's Research Institute, University of Texas Southwestern, Dallas, TX
³Division of Hematologic Malignancies and Cellular Therapy, Dept of Internal Medicine, Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX
⁴Department of Pediatrics, Division of Hematology and Oncology, UT Southwestern Medical Center, Dallas, TX

Zanshé Thompson, PhD^1*, Georgina A Anderson, MS, MA^2*, Melanie Rodriguez, MS^2*, Seth Gabriel, MS^2*, Vera Binder, MD^3*, Alison M Taylor, PhD^4* and Katie L Kathrein, PhD²

¹Department of Biomedical Engineering, University of South Carolina, Columbia, SC
²Department of Biological Sciences, University of South Carolina, Columbia, SC
³Dr. von Hauner University Children's Hospital, Ludwig Maximilian University, Munich, Germany
⁴Department of Pathology and Cell Biology and Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY