Luiza O. Perucci^1,2, Josiane C. Souza^3*, Lais C. Grossi^3*, Jessica A. M. Souza^3*, Isabella Zaidan^3*, Luciana P. Tavares^4*, Mauro M. Teixeira^5*, Robert J. Parmer^6*, Lindsey A. Miles² and Lirlandia P. Sousa^3*

¹Nucleus of Research on Biological Sciences, Federal University of Ouro Preto, Ouro Preto, Brazil
²Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA
³Department of Clinical Analysis, Federal University of Minas Gerais, Belo Horizonte, Brazil
⁴Brigham and Women’s Hospital, Harvard Medical School, Boston, MA
⁵Federal University of Minas Gerais, Belo Horizonte, Brazil
⁶Department of Medicine, University of California San Diego and Veterans Administration San Diego Healthcare System, San Diego, CA

Nicole Rhoads^1*, Michael Wong, PhD^2*, Benjamin Li, MD^2*, Michael Holinstat, PhD³ and Raymond Adili, MD³

¹Research Institute, Bloodworks Northwest, Seattle, WA
²Lee’s Pharmaceutical Holdings Ltd., Shatin, Hong Kong
³Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI

Enhao Li^1*, Zekun Li, MD^2*, Jing Dai, M.D. Ph.D.^3*, Guoqing Liu^4*, Jie Sun^5*, Zhenping Chen, PhD, MD^6*, Runhui Wu, MD, PhD^7*, Xuefeng Wang, M.D.^8* and Wenman WU, MD^9*

¹Faculty of Laboratory Medicine, Ruijin Hospital affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China
²Hemophilia Comprehensive Care Center, Beijing Children's Hospital, Capital Medical University, Shanghai, China
³Faculty of Laboratory Medicine, Ruijin hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
⁴Hemophilia Comprehensive Care Center, Beijing Children's Hospital, Capital Medical University, Beijing, China
⁵Beijing Children's Hospital, Capital Medical University, Beijing, China
⁶Hemophilia Comprehensive Care Center, Beijing Children’s Hospital, Capital Medical University, Beijing, China
⁷Department of Hematology, National Center for Children's Health, Beijing Children's Hospital, Beijing, China
⁸Faculty of Laboratory Medicine, Ruijin hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, CHN
⁹Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China, shanghai, PA, China

Kuniyoshi Mizumachi, MD^1*, Yuto Nakajima, MD^2*, Naruto Shimonishi, MD, PhD^3*, Shoko Furukawa, MD, PhD^1*, Kenichi Ogiwara, MD, PhD^1*, Masahiro Takeyama, MD, PhD¹, Midori Shima, MD, PhD⁴ and Keiji Nogami, MD^1*

¹Department of Pediatrics, Nara Medical University, Kashihara, Japan
²Advanced Medical Science of Thrombosis and Hemostasis, Nara medical University, Kashihara, Japan
³The Course of Thrombosis and Hemostasis Molecular Pathology, Nara medical University, Kashihara, Japan
⁴Thrombosis and Hemostasis Research Center, Nara Medical University, Kashihara, Japan

Michael Stobb^1*, Dougald Monroe, PhD², Keith B. Neeves, PhD³, Suzanne Sindi^4*, Aaron Fogelson^5* and Karin Leiderman^6*

¹Coe College, Cedar Rapids, IA
²Hematology and Oncology, School of Medicine, University of North Carolina, Chapel Hill, NC
³Departments of Bioengineering and Pediatrics, University of Colorado Denver, Aurora, CO
⁴University of California Merced, Merced, CA
⁵University of Utah, Salt Lake City, UT
⁶University of North Carolina, Chapel Hill, Chapel Hill

Dino Mehic, MD^1*, Daniel Kraemmer, MD^2*, Alexander Tolios, MD^3*, Julia Bücheler^4*, Peter Quehenberger, MD^5*, Cihan Ay, MD^6*, Ingrid Pabinger, MD⁴ and Johanna Gebhart, MD^7*

¹Department of Medicine I, Clinical Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria
²Department of Medicine I, Clinical Division of Hematology and Hemostaseology, Medical University Vienna, Vienna, AUT
³Department of Blood Group Serology and Transfusion Medicine, Medical University of Vienna, Vienna, AUT
⁴Clinical Division of Haematology and Haemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria
⁵Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria
⁶Department of Medicine I, Clinical Divison of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria
⁷Department of Medicine I, Clinical Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna, AUT

Bilgimol Chumappumkal Joseph, PhD, Richard FW Barnes, PhD^* and Annette von Drygalski, MD, Pharm D

Department of Medicine, Division of Hematology/Oncology, University of California San Diego, San Diego, CA

Tia CL Kohs^1*, Iván Parra-Izquierdo^1*, Helen Vu^1*, Monica T Hinds^1*, Joseph J Shatzel, MD¹, Joseph E Aslan, PhD², Michael Wallisch, PhD^3*, Erik I Tucker, PhD³, Christina U Lorentz, PhD^3*, Cristina Puy^4*, David Gailani, MD⁵ and Owen JT McCarty, PhD^1*

¹Department of Biomedical Engineering, Oregon Health & Science University, Portland, OR
²Knight Cardiovascular Institute, Oregon Health & Science University, Portland, OR
³Aronora, Inc., Portland, OR
⁴Department of Biomedical Engineering, Oregon Health %26 Science University, Portland, OR
⁵Vanderbilt University, Nashville, TN