John C Kostyak, PhD¹, Sharath S Sarojini, PhD^1* and Ulhas P. Naik, PhD²

¹Cardeza Center for Hematologic Research, Thomas Jefferson University, Philadelphia, PA
²Cardeza Foundation for Hematologic Research and Center for Vascular Biology Research, Department of Medicine, Thomas Jefferson University, Philadelphia, PA

Young Jun Shim, PhD^1*, Pat Rayman^2*, Paul Pavicic^2*, Shadi Swaidani, MD, PhD^2*, Alok A Khorana, MD³, Marcela Diaz-Montero, PhD^2* and Keith R. McCrae, MD¹

¹Cardiovascular & Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH
²Center for Immunotherapy and Precision Immuno-Oncology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH
³Department of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH

Shuwen Wang^1* and Jun Peng^2*

¹Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China
²Department of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China

Annina Capraru^1*, Tiphaine Ruggeri, PhD^2*, Noelia Schärz^3*, Laura Delvasto-Nunez^4*, Justine Brodard^5*, Gerard van Mierlo^4*, Johanna A. Kremer Hovinga Strebel, MD¹, Anne Angelillo-Scherrer, MD-PhD¹, Ilse Jongerius, PhD^4* and Sacha Sergio Zeerleder, MD, PhD^6*

¹Inselspital, Department of Hematology and Central Hematology Laboratory, University Hospital Bern, Bern, Switzerland
²Inselspital, University of Bern Department for Biomedical Research, Bern, Switzerland, Bern, CHE
³Inselspital, University of Bern Department for Biomedical Research, Bern, Switzerland, Bern, Switzerland
⁴Landsteiner Laboratory (AMC), Amsterdam University Medican Centers, Amsterdam, Netherlands
⁵Inselspital, University of Bern Department for Biomedical Research, Bern, Switzerland, 3010, Bern, Switzerland
⁶Haematologie, Luzerner Kantonsspital, Luzern, Switzerland

Leo Nicolai^1*, Rainer Kaiser, MD^2*, Quentin Loew^3*, Lisa Kammerer^4*, Karsten Spiekermann⁵ and Steffen Massberg^6*

¹Ludwig-Maximilians University, Munich, Germany
²Medizinische Klinik Und Poliklinik I, Klinikum Der Universität München, Muenchen, DEU
³Medizinische Klinik und Poliklinik I, Munich, Germany
⁴Medizinische Klinik und Poliklinik I, LMU Klinikum, Munich, Germany
⁵Department of Medicine III, Laboratory for Leukemia Diagnostics (LfL), University Hospital, LMU Munich, Munich, Germany
⁶Medizinische Klinik und Poliklinik I, Muenchen, Germany

Hailey Harris, BS¹, Sanjay Khandelwal, PhD², Lubica Rauova, MD, PhD³, John Lambris, PhD^4*, Brandon Garcia, PhD^5*, Douglas B. Cines, MD⁶ and Gowthami M. Arepally, MD²

¹Duke University School of Medicine, Durham, NC
²Division of Hematology, Duke University Medical Center, Durham, NC
³Division of Hematology,, Children's Hospital of Philadelphia, Philadelphia, PA
⁴University of Pennsylvania, Philadelphia, PA
⁵Department of Microbiology & Immunology, East Carolina University, Greenville, NC
⁶University of Pennsylvania PSOM, Philadelphia, PA

Jan Zlamal^1*, Tamam Bakchoul, MD^2,3,4, Anurag Singh^5*, Karoline Weich^6* and Karina Althaus^2,6*

¹University Hospital of Tuebingen, Institute for Clinical and Experimental Transfusion Medicine (IKET), Tubingen, Germany
²Center for Clinical Transfusion Medicine ZKT GmbH, Tübingen, Germany
³Center for Clinical Transfusion Medicine ZKT GmbH, Tuebingen, Germany
⁴Institute for Clinical and Experimental Transfusion Medicine, University Hospital Tübingen, Tübingen, Germany
⁵University Hospital of Tuebingen, Institute for Clinical and Experimental Transfusion Medicine (IKET)University Hospital of Tuebingen, Germany, Tübingen, Germany
⁶University Hospital of Tuebingen, Institute for Clinical and Experimental Transfusion Medicine (IKET), Tübingen, Germany

Brian Storrie, PhD¹, Irina D Pokrovskaya, MS^2*, Michael W. Webb, Ph.D.^3*, Smita Joshi, Ph.D.^4*, Sidney W Whiteheart, PhD⁵, Maria Aronova, PhD^6* and Richard D. Leapman^7*

¹Department of Physiology and Cell Biology, University of Arkansas for Medical Sciences, Cleveland, OH
²Department of Physiology and Cell Biology, University of Arkansas for Medical Sciences, Little Rock, AR
³Physiology and Biophysics, University of Arkansas Med Sci, Little Rock, AR
⁴Department of Biochemistry, University of Kentucky, Lexingtton, KY
⁵Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY
⁶Laboratory for Cellular Imaging and Molecular Biophysics, NIH, NIBIB, Bethesda, MD
⁷National Institute of Biomedical Imaging aand Bioengineering, National Institutes of Health, Bethesda, MD

Bárbara Gomes Barion^1*, Tania Rubia Rocha^2*, Ho Yeh-Li^1*, Paula Ribeiro Villaça, MD, PhD^3*, Bruna M Mazetto, PhD^4*, Erica Okasaki^5*, Bianca Stefanello^6*, Cynthia Rothschild^7*, Vanderson Gomes Rocha, M.D^8* and Fernanda Andrade Orsi, MD^9,10

¹Hospital das Clínicas da Faculdade de Medicina da USP, São Paulo, Brazil
²Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil
³Hospital das Clínicas da Faculdade de Medicina da USP, São Paulo, SP, Brazil
⁴School of Medical Science, University of Campinas, Campinas, Brazil
⁵Hospital das Clinicas da Faculdade de Medicina da USP, São Paulo, Brazil
⁶Hospital das Clínicas da Faculdade de Medicina da USP, São Paulo, BRA
⁷Hospital das Clínicas da Faculdade de Medicina da USP, Sao Paulo, BRA
⁸Faculdade de Medicina de Sao Paulo, Sao Paulo, Brazil
⁹Clinical Pathology, Unicamp, Campinas, Brazil
¹⁰Hematology and Hemotherapy Center, University of Campinas, Campinas, Brazil

Ciuffini Leonardo Augusto^1,2*, Aurelien Delluc, MD, PhD^3*, Tzu-Fei Wang, MD, MPH⁴, Corrado Lodigiani, MD, PhD^5* and Marc Carrier, MD, MSc^3,6

¹Center for Thrombosis and Hemorrhagic Diseases, Humanitas Clinical and Research Hospital, Rozzano, Milano, Italy
²Department of Medicine, The Ottawa Hospital Research Institute, Ottawa, ON, Canada
³Department of Medicine, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada
⁴Department of Medicine, The Ottawa Hospital, Ottawa, ON, Canada
⁵Center for Thrombosis and Hemorrhagic Diseases, Humanitas Clinical and Research Hospital, Rozzano (MI), ITA
⁶Department of Medicine, The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada

Cecily Allen, MD^1*, Ayesha Butt, MBBS^2*, Xiwen Zhao^3*, Fangyong Li, PhD^4*, Parveen Bahel^5*, C-Hong Chang, PhD^6*, Hyung Chun, MD^7*, Sean Gu, MD, PhD^1*, John Hwa, MD^1*, Sofia Jakab, MD^8*, Bonnie Chen^9*, Guadalupe Garcia-Tsao, MD^8*, Henry Rinder, MD¹⁰, Uyen To, MD^8*, Matthew McConnell, MD^8*, Alfred I Lee, MD, PhD² and Alexander Pine, MD, PhD¹¹

¹Yale School of Medicine, New Haven, CT
²Classical Hematology, Section of Hematology, Yale University School of Medicine, New Haven, CT
³Yale School of Public Health, New Haven
⁴Yale School of Public Health, New Haven, CT
⁵Yale University School of Medicine, Department of Laboratory Medicine, New Haven
⁶Yale University School of Medicine, New Haven, CT
⁷Department of Medicine, Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, CT
⁸Yale School of Medicine, New Haven
⁹Yale Liver Center, Yale School of Medicine, New Haven
¹⁰Departments of Laboratory Medicine & Medicine (Hematology), Yale School of Medicine, New Haven, CT
¹¹Department of Medicine, Section of Hematology, Yale School of Medicine, New Haven, CT

Michelle M. Luo, B.S.^1,2*, Yaqiu Sang, PhD^1,2, Maria N. Barrachina, PhD³, Andrew P. Stone, PhD^3*, Keely G. Davey, PhD^1,2*, Yi Yang, PhD^1,2*, Lori A. Holle, PhD^1,2*, Tomohiro Kawano, MD, PhD^1,4*, Nigel Mackman, PhD^4,5, Matthew J. Flick, PhD^1,2, Kellie R. Machlus, PhD³ and Alisa S. Wolberg, PhD^1,2

¹UNC Blood Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC
²Department of Pathology and Lab Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC
³Vascular Biology Program, Harvard Medical School and Boston Children's Hospital, Boston, MA
⁴Department of Medicine, Division of Hematology, University of North Carolina at Chapel Hill, Chapel Hill, NC
⁵Department of Medicine, Division of Hematology, UNC Blood Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC

Robert H Lee, PhD^1,2, Tanvi Rudran^2*, Silvio Antoniak^3*, Alisa S. Wolberg, PhD^4,5 and Wolfgang Bergmeier^1,6

¹UNC Blood Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC
²Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC
³UNC Blood Research Center, Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC
⁴Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC
⁵UNC Blood Research Center, University of North Carolina At Chapel Hill, Chapel Hill, NC
⁶Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill

Yilei Hong^1*, Yingying Shen^2*, Qi Liu^1*, Jingjie Dong^3*, Jingjing Xiang^2*, Wenbin Liu^2*, Yiping Shen^2*, Liqiang Wu^2*, Yuhong Zhou^2*, Baodong Ye^2* and Dijiong Wu, MD, PhD²

¹The First School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China
²Department of Hematology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China
³The First School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, AL, China

Romy de Laat-Kremers, PhD^1*, Denis Wahl, MD, PhD^2*, Stéphane Zuily, MD, PhD^2*, Marisa Ninivaggi, PhD^3*, Veronique Regnault, PhD^2*, Jacek Musial, MD, PhD^4*, Philip G. de Groot, PhD^3*, Katrien Devreese, PhD, MD^5,6* and Bas de Laat, MD, PhD^1,3

¹Department of Data Analysis and Artificial Intelligence, Synapse Research Institute, Maastricht, Netherlands
²Vascular Medicine Division, Centre Hospitalier Universitaire de Nancy, Nancy, France
³Department of Functional Coagulation, Synapse Research Institute, Maastricht, Netherlands
⁴2nd Department of Internal Medicine, Jagiellonian University Medical College, Krakow, Poland
⁵Coagulation Laboratory, Department of Clinical Chemistry, Microbiology and Immunology, Ghent University Hospital, Ghent, Belgium
⁶Department of Diagnostic Sciences, Ghent University, Ghent, Belgium

Xianghui Zhou^1*, Zhipeng Cheng^2* and Yu Hu, MD^3*

¹Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
²Union Hospital, Tongji Medical College, Huazhong University of Science and Techn, Wuhan, CHN
³Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

Young Jun Shim, PhD^1*, Yohei Hisada, PhD², Shadi Swaidani, MD, PhD^3*, Paul Pavicic^3*, Alok A Khorana, MD⁴, Marcela Diaz-Montero, PhD^3*, Nigel Mackman, PhD² and Keith R. McCrae, MD¹

¹Cardiovascular & Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH
²Department of Medicine, Division of Hematology, UNC Blood Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC
³Center for Immunotherapy and Precision Immuno-Oncology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH
⁴Department of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH

Megan E Barney^1*, Anh Le-Cook^1*, Naly Setthavongsack^1*, Randy Woltjer, MD, PhD^2*, Gabriel Nager^1* and Khanh Nguyen, MD¹

¹Oregon Health and Sciences University, Portland, OR
²Oregon Health and Science University, Portland, OR