-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

113. Hemoglobinopathies, Excluding Thalassemia: Basic and Translational: Poster III

Symposia: Hemoglobinopathies, Excluding Thalassemia: Basic and Translational Program: Oral and Poster Abstracts
Type: Poster
Monday, December 12, 2022: 6:00 PM-8:00 PM
Hall D (Ernest N. Morial Convention Center)

Caroline E. Kuczynski, BS1, Iuri V. Perisse, Ph.D.2*, Misha Regouski2*, Elmira Alipour, B.S.3*, Cecily LaPradd4*, Ying Liu, Ph.D.2*, Michael W. Beaty, M.D.4*, Daniel B. Kim-Shapiro, Ph.D.3*, Anthony Atala, M.D.1*, Irina Polejaeva, Ph.D.2*, Christopher D. Porada, Ph.D.1* and M. Graca Almeida-Porada, MD5

1Fetal Research and Therapy Program, Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC
2Utah State University, Logan, UT
3Department of Physics, Wake Forest University, Winston-Salem, NC
4Wake Forest School of Medicine, Winston-Salem, NC
5Fetal Research and Therapy Program, Wake Forest Institute For Regenerative Medicine, Winston-Salem, NC

Satheesh Chonat, MD1, Jayre A Jones, BS2*, Seema R Patel, PhD3*, Patricia E Zerra, MD4,5, Lauren A Jeffers6*, Ryan Philip Jajosky, MD7*, Connie M. Arthur, PhD8, Michael Koval, PhD6*, Clinton H. Joiner, MD, PhD9, David R. Archer, PhD10 and Sean R. Stowell, MD, PhD11,12

1Emory University, Aflac Cancer & Blood Disorders Center of Children’s Healthcare of Atlanta, Atlanta, GA
2Department of Pediatrics, Emory University, Atlanta, GA
3Aflac Cancer and Blood Disorders Center of Children's Healthcare of Atlanta and Department of Pediatrics, Emory University, Atlanta, GA
4Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta/Emory University School of Medicine, Atlanta, GA
5Department of Laboratory Medicine and Pathology, Emory University School of Medicine, Atlanta, GA
6Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, GA
7Department of Pathology, Brigham and Women's Hospital, Boston, MA
8Joint Program in Transfusion Medicine, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA
9Aflac Cancer & Blood Disorders Center of Children’s Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA
10Aflac Cancer & Blood Disorders Center of Children’s Healthcare of Atlanta and the Department of Pediatrics, Emory University, Atlanta, GA
11Harvard University, Boston, MA
12Joint Program in Transfusion Medicine, Brigham and Women's Hospital, Boston, MA

Ran An, PhD1, Yuncheng Man, PhD1*, Kevin Cheng2*, Tianyi Zhang2*, Chunsheng Chen, PhD3*, Erdem Kucukal2*, William Wulftange2*, Utku Goreke, MSc1*, Allison Bode, BS1*, Lalitha Nayak, MD4, Gregory M. Vercellotti, MD5, John D Belcher, PhD3, Jane Alison Little, MD6 and Umut A. Gurkan, PhD1

1Department of Mechanical & Aerospace Engineering, Case Western Reserve University, Cleveland, OH
2Case Western Reserve University, Cleveland, OH
3Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN
4Department of Medicine, Division of Hematology and Oncology, Case Western Reserve University and University Hospitals Cleveland Medical Center, Cleveland, OH
5Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN
6Department of Medicine, UNC Adult Sickle Cell Program, Chapel Hill, NC

Hemanth M Cherukury, MS1, Donovan A Argueta, PhD2, Natalie Garcia, BS3*, Raghda Fouda, MD/PhD4*, Stacy B Kiven, BSc5*, Graham Velasco6* and Kalpna Gupta, PhD3,7,8,9,10

1University of California Irvine, Irvine, CA
2Department of Medicine, Division of Hematology/Oncology, University of California, Irvine, Los Angeles, CA
3Department of Medicine, Division of Hematology/Oncology, University of California, Irvine, Irvine, CA
4University of California, Irvine, Orange, CA
5University of California, Irvine, Irvine, CA
6VA Long Beach Medical Center, Long Beach, CA
7SCIRE, Long Beach VA Medical Center, Long Beach, CA
8asD, asd, MN
9Vascular Biology Center, Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN
10Division of Hematology/Oncology, Department of Medicine, University of California, Irvine, Irvine, CA

Reilly L. Allison1*, Anthony Burand, PhD2*, Amanda M. Brandow, DO, MS3, Cheryl Stucky, PhD2* and Allison D. Ebert, PhD2*

1Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Wauwatosa, WI
2Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI
3Pediatric Hematology/Oncology, Medical College of Wisconsin and Children’s Research Institute of the Children’s Hospital of Wisconsin, Milwaukee, WI

Erica M.F. Gotardo, Ph.D.1*, Lidiane S. Torres, PhD2,3*, Lucas F.S. Gushiken, Ph.D.1*, Pamela L. Brito, M.Sc.1*, Flavia C. Leonardo, Ph.D.1*, Sergei Agoulnik, Ph.D.4*, Jiri Kovarik, Ph.D.5*, Andreas Bruederle6*, John Millholland, Ph.D.7*, Alessandra Vitaliti, Ph.D.8*, Irmgard Förster, Ph.D.9*, Fernando Ferreira Costa, M.D., Ph.D.1 and Nicola Conran, PhD1

1Hematology Center, University of Campinas - UNICAMP, Campinas - São Paulo, Brazil
2Ruth L. and David Gottesman Institute for Stem cell and Regenerative Medicine Research, Albert Einstein College of Medicine, New York, NY
3Hematology Center, University of Campinas - UNICAMP, Campinas, Brazil
4Novartis Precision Medicine (former affiliation), Cambridge, MA
5Novartis Institutes for BioMedical Research, Basel, Switzerland
6Novartis Pharma AG, Basel, Switzerland
7Novartis Precision Medicine, Cambridge, MA
8Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland
9Immunology and Environment, University of Bonn, Bonn, Germany

Ali San, BS1,2, Gowtham K Annarapu, PhD3, Lynda Little-Ihrig4*, Enrico M. Novelli, MD, MS5 and Sruti Shiva, PhD3,6

1Vascular Medicine Institute, University of Pittsburgh, Kansas City, MO
2Kansas City University College of Osteopathic Medicine, Kansas City, MO
3Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA
4Pittsburgh Heart, Lung, and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA
5Heart, Lung and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA
6Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA

Myrthe J. van Dijk1,2*, Marissa J.M. Traets1*, Brigitte A. van Oirschot1*, Jonathan R.A. de Wilde1*, Jennifer Bos1*, Wouter W. van Solinge1*, Margaret J. Koziel3*, Revati Wani3,4*, Eduard J. Van Beers, MD, PhD2*, Richard van Wijk1* and Minke A.E. Rab, MD, PhD1,5*

1Central Diagnostic Laboratory - Research, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands
2Center for Benign Hematology, Thrombosis and Hemostasis - Van Creveldkliniek, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands
3Axcella Therapeutics, Cambridge, MA
4Boehringer Ingelheim Pharmaceuticals, Cambridge, MA
5Department of Hematology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands

Ravi Vats, PhD1,2, Rikesh K Dubey, PhD1, Gabriel Njikang, PhD3*, John Paderi, PhD4* and Prithu Sundd, PhD2,5,6

1Pittsburgh Heart, Lung and Blood Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA
2Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA
3IHP Therapeutics, San Francisco, CA
4IHP Therapeutics, San Carlos, CA
5Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA
6Pittsburgh Heart, Lung and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA

Anne Gallivan, BS1*, Amarachi Kanu1*, Mikail Alejandro, BS1*, Nebeyat Zekaryas1*, Hart Horneman, BS1*, Jagadeesh Ramasamy, PhD2*, Lenny Hong2*, Donald Lavelle, PhD2,3, Alan Diamond, Ph.D.2*, Robert E. Molokie, MD2, Elliott P. Vichinsky, MD1 and Angela Rivers, MD1

1UCSF Benioff Children's Hospital Oakland, Oakland, CA
2University of Illinois at Chicago, Chicago, IL
3Jesse Brown VA Medical Center, Chicago, IL

Stephen C Rogers, PhD1*, Zohreh Safari, PhD2*, Mary Brummet1*, Qihong Wang, MD1*, Joy Okhuevbie, BS1*, Nicole Glynn-Cunningham, RN3*, Jennie Y. Law, MD4, Maria R. Baer, MD4 and Allan Doctor, MD5

1Center for Blood Oxygen Transport and Hemostasis, University of Maryland School of Medicine, Baltimore, MD
2Center for Blood Oxygen and Hemostasis, University of Maryland, Baltimore, Baltimore, MD
3Department of Hematology, University of Maryland Medical Center, Baltimore, MD
4Department of Medicine, University of Maryland School of Medicine, Baltimore, MD
5Director, Center for Blood Oxygen Transport and Hemostasis, University of Maryland School of Medicine, Baltimore, MD

James Fan, MD1*, Joanna Gemel, PhD2*, Theodore Lang, BA3, Eric C. Beyer, MD, PhD2* and Gabrielle Lapping-Carr, MD2

1Department of Internal Medicine, The University of Chicago Medical Center, Chicago, IL
2Department of Pediatrics, Section of Hematology and Oncology, The University of Chicago, Comer Children's Hospital, Chicago, IL
3The University of Chicago Pritzker School of Medicine, Chicago, IL

Nicolas Hebert1,2,3*, Laurent Kiger, PhD1,3*, Alexis Chenneviere, PhD4*, Anne-Laure Pham Hung D'Alexandry D'Orengiani, PhD3*, France Pirenne, MD, PhD2,5, Orsolya Czakke6*, Bela Farago6*, Lionel Porcar6*, Stephane Longeville, PhD4* and Pablo Bartolucci, MD, PhD1,3*

1Université Paris-Est Créteil, INSERM, IMRB, Laboratory of excellence LABEX GRex, Créteil, France
2Etablissement Français du Sang, Creteil, France
3Sickle Cell Referral Center - UMGGR, Henri Mondor Hospital, AP-HP, Creteil, France
4Laboratoire Léon Brillouin, CEA-CNRS, Université de Paris-Saclay, Gif-sur-Yvette, France
5IMRB INSERM U955 , GR-Ex (Paris) and Paris-Est-Créteil University, Créteil, France
6Institut Laue-Langevin (ILL), Grenoble, France

Jasmin Martin, MD1*, Lily C. Wain, BA1*, Elisabeth F Heuston, PhD1*, Ilya Gertsman, PhD2* and David M Bodine, PhD1

1NHGRI, National Institutes of Health, Bethesda, MD
2Clarus Analytical, San Diego, CA

Utku Goreke, MSc1*, Allison Bode, BS1*, Ran An, PhD1, Jane Alison Little, MD2 and Umut A. Gurkan, PhD1

1Department of Mechanical & Aerospace Engineering, Case Western Reserve University, Cleveland, OH
2Department of Medicine, UNC Adult Sickle Cell Program, Chapel Hill, NC

Omika Katoch, PhD1*, Ziming Li2*, Ravi Vats, PhD1, Rikesh K K. Dubey, PhD1, Tomasz W. Kaminski, PharmD1, Tomasz Brzoska, PhD1, Prithu Sundd, PhD1, Enrico M. Novelli, MD3 and Tirthadipa Pradhan-Sundd, PhD4

1Pittsburgh Heart, Lung and Blood Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA
2University of Pittsburgh, Pittsburgh, PA
3Pittsburgh Heart, Lung, and Blood Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA
4Hematology-Oncology, University of Pittsburgh, Pittsburgh, PA

Nassima Djouder1,2,3*, Nicolas Hebert1,3,4*, Stephane Moutereau, MD1,5*, Emmanuel Adu1,3*, Steeve Lowenski1,3*, Anne-Laure Pham Hung D'Alexandry D'Orengiani, PhD3*, France Pirenne, MD, PhD4,6, Carlosse Keumeugni2*, Corinne Duguet, MD2 and Pablo Bartolucci, MD, PhD1,3*

1Université Paris-Est Créteil, INSERM, IMRB, Laboratory of excellence LABEX GRex, Créteil, France
2ADDMEDICA, Paris, France
3Sickle Cell Referral Center - UMGGR, Henri Mondor Hospital, AP-HP, Creteil, France
4Etablissement Français du Sang, Creteil, France
5Département de Biochimie-Biologie Moléculaire-Pharmacologie-Génétique Médicale, Hôpital Henri Mondor, AP-HP, Creteil, France
6INSERM-U955, Equipe 2, Laboratoire D'Excellence, GRex, Institut Mondor, Créteil, France

Ioannis Papassotiriou, PhD1, Anastasia Bartzeliotou, PhD2*, Pagona Flevari, MD3*, Maria Dimopoulou, MD3*, Charalambos Kapogiannis, MD1*, Vassiliki Kappou, MSc1*, Veroniki Komninaka, MD3*, Konstantina Repa, MD3*, Aimilia Mantzou, PhD1*, Alexandra Margeli, PhD2*, Eleni Pergantou, MD, PhD4*, Christos Poziopoulos, MD5* and Ersi Voskaridou, MD3*

1First Department of Pediatrics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
2Department of Clinical Biochemistry, "Aghia Sophia" Children's Hospital, Athens, Greece
3Centre of Excellence in Rare Hematological Disease-Hemoglobinopathies, "Laiko" General Hospital, Athens, Greece
4Haemophilia Centre/Haemostasis and Thrombosis Unit, Aghia Sophia Children's Hospital, Athens, AL, Greece
5Department of Hematology, METROPOLITAN Hospital, Athens, Greece

*signifies non-member of ASH