-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

112. Thalassemia and Globin Gene Regulation: Poster III

Symposia: Thalassemia and Globin Gene Regulation Program: Oral and Poster Abstracts
Type: Poster
Monday, December 12, 2022: 6:00 PM-8:00 PM
Hall D (Ernest N. Morial Convention Center)

Franco Locatelli, MD1, Mark C. Walters, MD2, Janet L. Kwiatkowski, MD, MSCE3, Marina Cavazzana, MD, PhD4,5,6, Suradej Hongeng, MD7, John B. Porter, MD, FRCP, FRCPath8*, Adrian J. Thrasher, MBBS, PhD, FMedSci9*, Andreas E. Kulozik, MD, PhD10*, Isabelle Thuret, MD11*, John E. J. Rasko, MBBS, PhD12,13,14, Evangelia Yannaki, MD15*, Martin G. Sauer, MD16, Shamshad Ali17*, Himal Thakar, MD17*, Katiana Gruppioni, MPH17* and Alexis A. Thompson, MD, MPH18

1IRCCS Ospedale Pediatrico Bambino Gesú, Catholic University of the Sacred Heart, Rome, Italy
2University of California San Francisco Benioff Children’s Hospital, Oakland, CA
3Children’s Hospital of Philadelphia and Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
4Université de Paris, Paris, France
5Biotherapy Department and Clinical Investigation Center, Assistance Publique Hopitaux de Paris, Inserm, Paris, France
6Imagine Institute, Paris, France
7Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
8University College London Hospital, London, United Kingdom
9UCL Great Ormond Street Institute of Child Health and Great Ormond Street Hospital NHS Trust, London, United Kingdom
10Molecular Medicine Partnership Unit (MMPU), European Molecular Biology Laboratory (EMBL), and Department of Pediatric Oncology, Hematology, and Immunology, University of Heidelberg, Heidelberg, Germany
11Hôpital de la Timone, Marseille, France
12Cell and Molecular Therapies, Royal Prince Alfred Hospital, Camperdown, Australia
13The University of Sydney, Sydney, Australia
14Centenary Institute, Camperdown, Australia
15Gene and Cell Therapy Center, Hematology-HCT Unit, G. Papanikolaou Hospital, Thessaloniki, Greece
16Department of Pediatric Hematology/Oncology and Blood Stem Cell Transplantation, Hannover Medical School, Hannover, Germany
17bluebird bio, Inc., Somerville, MA
18Ann & Robert H. Lurie Children’s Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, IL

Mohammad Ammad Ud Din, MBBS1,2, Hania Liaqat, MD3*, Moazzam Shahzad, MD1,2*, Ayesha Javed, MBBS4* and Michael Jaglal, MD5

1H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
2Hematology/ Oncology, University of South Florida, Tampa, FL
3Rochester General Hospital, Rochester, NY
4King Edward Medical University, Lahore, Pakistan
5Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL

Polyxeni Delaporta, PhD1*, Alexandra Kourakli, MD, PhD2*, Sophia Delicou, MD3*, Michael D. Diamantidis, MD, PhD, MSc4, Chrysoula Kalkana, MD5*, Efthymia Vlachaki, MBBS6*, Eftychios Eftychiadis, MD7*, Ioannis Lafiatis, BSc, MD8*, Despoina Pantelidou, MD, PhD9*, Argiris Symeonidis, MD, PhD10, Vasileios Lazaris, MD11*, Aikaterini Xydaki, MD12*, Achilles Manafas, MD4*, Loukia Evliati, MD13*, Filippos Klonizakis, MD14*, Ioanna Manika, MD15*, Despoina Papadopoulou, MD9*, Marianna Chatzieleftheriou, MD16*, Konstantina Toutoudaki, MD17*, Dimitra Kyriakopoulou, MD17* and Antonis Kattamis, MD18

1Thalassemia Unit, First Department of Pediatrics, National and Kapodistrian University of Athens, 'Aghia Sophia' Children's Hospital, ATHENS, Greece
2Thalassemia and Hemoglobinopathies' Unit, Hematology Division, Dept Int Medicine University Hospital of Patras, PATRA, Greece
3Thalassemia and Sickle Cell Unit, Hippocratio General Hospital, Athens, Greece
4Thalassemia and Sickle Cell Disease Unit, General Hospital of Larissa, Larissa, Greece
5Thalassemia and Sickle Cell Disease Unit- Blood Bank Service, Evaggelismos General hospital, Athens, Greece
6Adults Thalassemia Unit, Hippokration Hospital, Thessaloníki Thalassemia Therapy and Sickle Cell Disease Unit, Thessaloniki, Greece
7Thalassemia Therapy and Sickle Cell Disease Unit, General Hospital Karditsa, Karditsa, Greece
8Thalassemia and Sickle Cell Disease Unit, “Vostanio” General Hospital of Mytilene, Mytilini, Greece
9Thalassemia and Sickle Cell Disease Unit, AHEPA University Hospital, Thessaloniki, Thessaloniki, Greece
10Hematology Division, Department of Internal Medicine, University of Patras, Patras, Greece
11Thalassemia and Hemoglobinopathies' Unit, Hematology Division, Dept Int Medicine University Hospital of Patras, Patras, Greece
12Thalassemia and Sickle Cell Unit Hippocratio General Hospital, Athens, Athens, Greece
13Thalassemia and Sickle Cell Disease Unit- Blood Bank Service, Evaggelismos General hospital, Athens,, Athens, Greece
14Adults Thalassemia Unit, Hippokration Hospital, Thessaloníki Thalassemia Therapy and Sickle Cell Disease Unit, Thessaloniki, AL, Greece
15Thalassemia Therapy and Sickle Cell Disease Unit, General Hospital Karditsa,, Kardirsa, Greece
16Thalassemia Unit, First Department of Pediatrics, National and Kapodistrian University of Athens, 'Aghia Sophia' Children's Hospital,, Athens, Greece
17Thalassemia Unit, First Department of Pediatrics, National and Kapodistrian University of Athens, 'Aghia Sophia' Children's Hospital, Athens, Greece
18National and Kapodistrian University of Athens, Athens, Greece

Andrea Piolatto, MSc1*, Gennaro Boccia, PhD1*, Alessandra Manca, MPharm2*, Carmen Gaglioti, MD1*, Teresa Ceglie, MD1*, Caterina Cosentino3*, Luca Beratto, PhD3*, Jessica Cusato, PhD2*, Patrizia Falco1*, Silvia De Carlo3*, Filomena Longo, MD1,4*, Antonella Roetto, PhD1*, Antonio Piga, MD1, Antonio D'Avolio, MSc, SM5,6*, Alberto Rainoldi, PhD7* and Giovanni Battista Ferrero, MD, PhD1*

1Department of Clinical and Biological Sciences, University of Torino, Torino, Italy
2Clinical Pharmacology and Pharmacogenetics, University of Torino, Torino, Italy
3School of Exercise and Sport Science, SUISM, University of Torino, Torino, Italy
4Azienda Ospedaliero Universitaria S. Anna, Regional HUB Centre for Thalassaemia and Haemoglobinopathies, Department of Medicine, Ferrara, Italy
5Department of Clinical Pharmacology and Pharmacogenetics, University of Torino, Turin, Italy
6CoQua Lab srl, Torino, Italy
7Department of Medical Sciences, University of Torino, Torino, Italy

Ali T. Taher, MD, PhD, FRCP1, Vip Viprakasit2*, Maria Domenica Domenica Cappellini, MD3, Antonio Piga, MD4, John B. Porter, MD, FRCP, FRCPath5*, Thomas D. Coates, MD6,7, Khaled M. Musallam8,9*, Gian Luca Forni10*, Jeevan K. Shetty, MD FRCP11*, Marija Bosilkovska Weisskopf11*, Richard Wei12*, Wen-Ling Kuo12* and Antonis Kattamis, MD13

1Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon
2Siriraj Research Hospital, Mahidol University, Bangkok, Thailand
3Fondazione IRCCS Ca’ Granda Policlinico Hospital, University of Milan, Milan, Italy
4University of Turin, Turin, Italy
5University College London, University College London Hospitals, London, United Kingdom
6USC Keck School of Medicine, Los Angeles, CA
7Cancer and Blood Disease Institute, Children’s Hospital Los Angeles, Los Angeles, CA
8Thalassemia Center, Burjeel Medical City, Abu Dhabi, United Arab Emirates
9International Network of Hematology, London, United Kingdom
10Center for Congenital Anemias, Galliera Hospital, Genoa, Italy
11Celgene International Sàrl, a Bristol-Myers Squibb Company, Boudry, Switzerland
12Bristol Myers Squibb, Princeton, NJ
13First Department of Pediatrics, National and Kapodistrian University of Athens, Athens, Greece

Elena E. Solomou, MD1, Polyxeni Delaporta, PhD2*, Laidou Stamatia, PhD3*, Efthymia-Vasilina Katsika4*, Marianna Chatzieleftheriou, MD5*, Konstantina Toutoudaki, MD6*, Stavros Glentis, PhD7*, Kostas Stamatopoulos8,9, Anastasia Chatzidimitriou9* and Antonis Kattamis, MD10

1Department of Internal Medicine, University of Patras Medical School, Rion, Greece
2Thalassemia Unit, First Department of Pediatrics, ‘Aghia Sophia’ Children’sHospital, National and Kapodistrian University of Athens , Athens, Greece, ATHENS, Greece
3CERTH, Thessaloniki, Greece
4Center for Research and Technology, Hellas, CERTH, Thessaloniki, Greece
5Thalassemia Unit, First Department of Pediatrics, National and Kapodistrian University of Athens, 'Aghia Sophia' Children's Hospital,, Athens, Greece
6Thalassemia Unit, First Department of Pediatrics, National and Kapodistrian University of Athens, 'Aghia Sophia' Children's Hospital, Athens, Greece
7Pediatric Hematology Oncology Unit, First Department of Pediatrics, National and Kapodistrian University of Athens, Aghia Sophia Children’s Hospital, Athens, Greece
8Institute of Applied Biosciences, CERTH, Asvestohori, Greece
9Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece
10Thalassemia Unit, First Department of Pediatrics, ‘Aghia Sophia’ Children’s Hospital, National and Kapodistrian University of Athens, ATHENS, Greece

Olivier Hermine, MD, PhD1,2, Maria Domenica Domenica Cappellini, MD3, Ali T. Taher, MD, PhD, FRCP4, Thomas D. Coates, MD5,6, Vip Viprakasit7*, Antonis Kattamis, MD8, Jeevan K. Shetty, MD FRCP9*, Marija Bosilkovska Weisskopf9*, Natalia Holot10*, Sadanand Vodala, PhD10, Wen-Ling Kuo10* and John B. Porter, MD, FRCP, FRCPath11*

1Imagine Institute, INSERM U1163, University of Paris, Paris, France
2Department of Hematology, Necker Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France
3Fondazione IRCCS Ca’ Granda Policlinico Hospital, University of Milan, Milan, Italy
4Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon
5USC Keck School of Medicine, Los Angeles, CA
6Cancer and Blood Disease Institute, Children’s Hospital Los Angeles, Los Angeles, CA
7Siriraj Research Hospital, Mahidol University, Bangkok, Thailand
8First Department of Pediatrics, National and Kapodistrian University of Athens, Athens, Greece
9Celgene International Sàrl, a Bristol-Myers Squibb Company, Boudry, Switzerland
10Bristol Myers Squibb, Princeton, NJ
11University College London, University College London Hospitals, London, United Kingdom

Sharjeel Syed, MD1, Kristen Wroblewski, MS2*, Radhika Peddinti, MD3, Gabrielle Lapping-Carr, MD4 and Wendy S Darlington, MD5

1University of Chicago, Chicago, IL
2Department of Public Health Sciences, University of Chicago, Chicago
3The University of Chicago Medicine, Chicago, IL
4Department of Pediatrics, Section of Hematology and Oncology, The University of Chicago, Comer Children's Hospital, Chicago, IL
5Department of Pediatrics, Section of Hematology and Oncology, The University of Chicago, Chicago, IL

*signifies non-member of ASH