Heinrich E Lob, PhD¹, Larisa Ivanova^1*, Beth Crowell^2*, Hyonjong Kim^1*, Vincent Idone^1*, Aris N Economides, PhD^1* and Sarah Hatsell, PhD^1*

¹Regeneron Pharmaceuticals, Inc., Tarrytown, NY
²Regeneron Pharmaceuticals, Regeneron Pharmaceuticals, Inc., Tarrytown, NY

Amaliris Guerra, PhD^1*, Ana Catarina Martins^2*, Ariel Rivera^3*, Nermi Parrow, PhD⁴, Raffaella Gozzelino, PhD^5*, Yelena Ginzburg, MD⁶, Robert E Fleming, MD⁷ and Stefano Rivella, PhD⁸

¹Department of Pediatrics, Division of Hematology, The Children’s Hospital of Philadelphia, Philadelphia, PA
²NOVA Medical School, Lisbon, PRT
³Children's Hospital Of Philadelphia, Philadelphia, PA
⁴Pediatrics, Saint Louis University School of Medicine, Saint Louis, MO
⁵Chronic Diseases Research Center (CEDOC), NOVA Medical School (NMS), Lisbon, PRT
⁶Division of Hematology Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY
⁷Pediatrics, Saint Louis University School of Medicine, University City, MO
⁸Children’s Hospital of Philadelphia, Philadelphia, PA

Lynette C.Y. Chee, MBBS, PhD, FRACP, FRCPA¹, David M Ross, MBBS, PhD, FRACP, FRCPA^2*, Shuh Ying Tan, MBBS^3*, Joel Wight, MBBS FRACP FRCPA⁴, George Kannourakis, MB.BS, B(Med)Sci, PhD, FRACP⁵, Miranda Ross^6*, Wei Feng, PhD^6*, Ying Jiang, PhD^6*, Harveen Dhillon Natarajan, PhD^6*, Christine Graham, PhD^7*, Christopher Rovaldi, MSc^6*, Simon Cooper, MBBS^6* and Jen L. Salstrom, MD, PhD⁶

¹Department of Clinical Haematology, The Royal Melbourne Hospital and Peter MacCallum Cancer Centre, Melbourne, VIC, Australia
²Department of Haematology, Flinders Medical Centre and University, Adelaide, SA, Australia
³St Vincent’s Hospital Melbourne, Fitzroy, VIC, Australia
⁴Townsville University Hospital, Douglas, QLD, Australia
⁵Fiona Elsey Cancer Research Institute and Federation University Australia, Ballarat, Australia
⁶Keros Therapeutics, Lexington, MA
⁷Keros Therapeutics, Haverhill, MA

Yue Chen, MS^1*, Will Savage, MD, PhD^1,2, Rajiv Panwar, PhD^1*, Richard Rodriguez, MS^1*, Min Wu, PhD³, John Quisel, PhD, JD^1* and Hua Yang, PhD^1*

¹Disc Medicine, Watertown, MA
²Disc Medicine, Boston, MA
³DISC Medicine, Cambridge, MA

Danielle Clucas^1,2,3*, Cavan Bennett, BMedSc PhD^3,4*, Ryan Steel, BBiomedSci PhD^3,5*, Ronan Mellin, BSc MBiomedSci PhD^3,5*, Sabrina Caiazzo, MSc BSc PhD^5*, Ute Schaeper, PhD^6*, Justin Boddey, BBiomedSci PhD^3,5*, Ricardo Ataide, PhD^4,7* and Sant-Rayn Pasricha, MD, PhD^3,8,9

¹Population Health and Immunity, Walter and Eliza Hall Institute of Medical Research, Parkville, Australia
²Diagnostic Haematology, The Royal Melbourne Hospital, Parkville, VIC, Australia
³Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia
⁴Population Health and Immunity, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia
⁵Infectious Diseases and Immune Defence, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia
⁶Silence Therapeutics GmbH, Berlin, Germany
⁷Department of Infectious Diseases, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, Australia
⁸Population Health and Immunity, Walter and Eliza Hall Institute of Medical Research, Fitzroy North, VIC, Australia
⁹Diagnostic Haematology, Royal Melbourne Hospital, Parkville, VIC, Australia

Aarif Ahsan^1*, Wei Fang^2*, Manuel Ugidos, PhD^3*, Danny V Jeyaraju, PhD^4,5*, Pierre Fenaux⁶, Uwe Platzbecker, MD⁷, Olivier Hermine, MD, PhD⁸, John B. Porter, MD, FRCP, FRCPath^9*, Rajasekhar N.V.S. Suragani, PhD¹⁰, Sadanand Vodala, PhD^4* and Anita K. Gandhi, PhD¹¹

¹Translational Development and Diagnostics, Bristol Myers Squibb, SUMMIT, NJ
²Bristol Myers Squibb, SUMMIT, NJ
³BMS Center for Innovation and Translational Research Europe (CITRE), a Bristol-Myers Squibb Company, Seville, Spain
⁴Bristol Myers Squibb, Princeton, NJ
⁵Translational Development and Diagnostics, Bristol Myers Squibb, Summit, NJ
⁶Service d'Hématologie Séniors, Hôpital Saint-Louis, Université Paris 7, Paris, France
⁷Medical Clinical and Policlinic 1, Hematology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany
⁸Department of Hematology, Necker Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France
⁹University College London Hospitals, University College London, London, United Kingdom
¹⁰Translational Medicine, Bristol Myers Squibb, SUMMIT, NJ
¹¹Translational Medicine Hematology, Bristol Myers Squibb, Summit, NJ

Katie Seu, PhD¹, Aikaterini Voulgaridou, MD^1*, Maria Stewart^1*, Jessica Meznarich, MD^2,3, Clarissa Johnson, MD^4*, Harald Junge^5*, Bryan Mackenzie, PhD^6*, Lionel Blanc, PhD^7,8, Jose A. Cancelas, MD^1,9,10 and Theodosia A. Kalfa, MD, PhD^1,10

¹Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
²Division of Hematology-Oncology, Department of Pediatrics, University of Utah, Salt Lake Cty, UT
³Primary Children's Hospital, Intermountain Healthcare, Salt Lake City, UT
⁴Pediatric Hematology-Oncology, Cook Children's Medical Center, Fort Worth, TX
⁵Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN
⁶Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, OH
⁷Department of Molecular Medicine and Pediatrics, Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY
⁸Institute of Molecular Medicine, The Feinstein Institutes for Medical Research, Manhasset, NY
⁹Hoxworth Blood Center, University of Cincinnati College of Medicine, Cincinnati, OH
¹⁰Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH

Min Wu, PhD¹, Sarah Ducamp, PhD², Yi Xiang^3*, Juan Putra, MD^2*, Mark D. Fleming, MD, DPhil², Brian MacDonald, MBChB, PhD^3* and Paul J Schmidt, PhD²

¹DISC Medicine, Cambridge, MA
²Department of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MA
³Disc Medicine, Watertown, MA

Maayan Levy, MS^1*, Gino Ferraro^2*, Li Li^2*, Yongshuai Han^3*, Lilian Varricchio, PhD^1*, Sara Fournier^2*, Xiuli An⁴, Ronald Hoffman, MD⁵, Adrian Fretland^2*, Anne Roulston^2* and Yelena Ginzburg, MD⁶

¹Icahn School of Medicine at Mount Sinai, New York
²Repare Therapeutics, Montreal, Canada
³New York Blood Center, New York
⁴Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY
⁵Tisch Cancer Institute, Division of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY
⁶Division of Hematology Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY

Grace Power^1*, Alexandra Stratas^2*, Carmen Landry^1*, Lisa Morrison, PDt^3*, Ketan Kulkarni, MD^4,5, Marsha Campbell-Yeo, PhD^3*, Balpreet Singh^1,2*, Michelle Higgins^2* and Satvinder Ghotra, MD^2*

¹Dalhousie University, Halifax, NS, Canada
²IWK Health Centre, Halifax, NS, Canada
³Pediatrics, IWK Health Centre, Halifax, NS, Canada
⁴Department of Pediatrics, Division of Hematology Oncology, IWK Health Centre, Halifax, NS, Canada
⁵Pathology, Dalhousie University, Halifax, NS, Canada

Faris Ali, BS¹, Nisha George, PhD^2*, Nermi Parrow, PhD³ and Robert E Fleming, MD^4,5

¹Pediatrics, Saint Louis University School of Medicine, St Louis, MO
²Saint Louis University School of Medicine, St Louis
³Pediatrics, Saint Louis University School of Medicine, Saint Louis, MO
⁴Pediatrics, Saint Louis University School of Medicine, University City, MO
⁵Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University, St. Louis, MO