Sarah B May, MS, MPH^1*, Jennifer La, PhD^2*, Emily Milner^3*, Nimrah Riaz, MS^3*, Christopher I Amos^4*, David A. Garcia, MD⁵, Marc Carrier, MD, MSc⁶, Neil Zakai, MD^7*, Nhan V Do, MD^8*, Mary Brophy, MD, MPH^2*, Vipul Chitalia, MD^9*, J. Michael Gaziano, MD, MPH^10*, Nathanael Fillmore^11* and Ang Li, MD, MS¹²

¹Baylor College of Medicine, Houston, TX
²Department of Medicine, VA Boston Healthcare System, Boston, MA
³Baylor College of Medicine, Houston
⁴Epidemiology and Population Sciences, Baylor College of Medicine, Houston, TX
⁵Division of Hematology, University of Washington, Seattle, WA
⁶Department of Medicine, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada
⁷Larner College of Medicine at the University of Vermont, Burlington, VT
⁸Boston University School of Medicine, Boston, MA
⁹VA Boston Healthcare System, Boston
¹⁰VA Boston Healthcare System, Boston, MA
¹¹VA Boston Healthcare System, Harvard Medical School, Jamaica Plain, MA
¹²Hematology-Oncology, Baylor College of Medicine, Houston, TX

Maya Gogtay, MD^1*, Mithil Gowda Suresh, MD^2*, Yuvaraj Singh, MD^2* and George M. Abraham, MD, MPH, MACP, FIDSA, FRCP^2*

¹Hospice and Palliative Care, University of Texas Health, San Antonio, San Antonio, TX
²Internal Medicine, Saint Vincent Hospital, Worcester, MA

Mitchell K. Higashi, PhD^1*, Paul Kruszka, MD^2*, Marra S. Francis, MD^3*, Kelly K. Parsons, PhD^4*, William K. Oh, M.D.^5,6 and Kenan Onel, M.D., Ph.D.^1,6

¹Sema4, Stamford, CT
²Medical, Sema4, Gaithersburg, MD
³Medical, Sema4, Stamford, CT
⁴Research, Sema4, Stamford, CT
⁵medical, Sema4, Stamford, CT
⁶Icahn School of Medicine at Mount Sinai, New York, NY

Jackie Kwong, PhD, PharmD¹, Syed Numan, M.D., M.B.A.^2*, Tina Hunter, Ph.D.^3*, Dalila Alves, MSc^3*, Anish Patel, DO, FACG^4* and Satish Shanbhag, MD^5*

¹Daiichi Sankyo, Inc., Basking Ridge, NJ
²American Regent, Norristown, PA
³CTI Clinical Trial & Consulting Services, Covington, KY
⁴Brooke Army Medical Center, Fort Sam Houston, TX
⁵Cancer Specialists of North Florida, Jacksonville, FL

Gili Kenet, MD^1,2, Beatrice Nolan^3*, Tadashi Matsushita, MD, PhD⁴, Guy Young, MD^5,6, Ting Quan, MS^7*, Viridiana Cano, MD⁸, Christian Sussebach^9*, Shauna Andersson, MD, PhD^8*, Baisong Mei, MD, PhD^8*, Marion Afonso, MSc^10* and Kaan Kavakli, MD, PhD^11*

¹Tel Aviv University, Tel Aviv, Israel
²Sheba Medical Center, Ramat Gan, Israel
³Our Lady's Children's Hospital, Dublin, Ireland
⁴Department of Transfusion Medicine, Nagoya University Hospital, Nagoya, Japan
⁵Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA
⁶Keck School of Medicine, University of Southern California, Los Angeles, CA
⁷Sanofi, Chengdu, China
⁸Sanofi, Cambridge, MA
⁹Sanofi, Frankfurt, Germany
¹⁰Sanofi, Chilly-Mazarin, France
¹¹Ege University Children’s Hospital, Clinic of Children’s Health and Diseases, Division of Pediatric Hematology, Izmir, Turkey

Lauren Shevell, MD¹ and Suman L Sood, MD²

¹Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI
²Division of Hematology/Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI

Mary Dang, MD¹, Kendra Malone^2*, Sean Rinzler, MD^3*, Jessica Garcia, MD² and Ayesha Zia, MD, MSc²

¹Department of Pediatrics, Division of Pediatric Hematology & Oncology, The University of Texas Southwestern Medical Center, Bedford, TX
²Department of Pediatrics, Division of Pediatric Hematology & Oncology, The University of Texas Southwestern Medical Center, Dallas, TX
³Department of Radiology, Division of Pediatric Radiology, The University of Texas Southwestern Medical Center, Dallas, TX

Suzy Bangudi^1,2, Divya Shankar, BS^2,3*, Charis Stanek, MA^3*, Laura Hart, MD^4*, Leena Nahata, MD^3,5*, Robert M Cronin, MD, MS⁶ and Susan E. Creary, MD, MSc^1,7

¹Center for Child Health Equity and Outcomes, Nationwide Children's Hospital, Columbus, OH
²College of Medicine, The Ohio State University, Columbus, OH
³Center for Biobehavioral Health, Nationwide Children's Hospital, Columbus, OH
⁴Primary Care Pediatrics, Nationwide Children's Hospital, Columbus, OH
⁵Division of Endocrinology, Nationwide Children's Hospital, Columbus, OH
⁶Department of Internal Medicine, The Ohio State University, Hilliard, OH
⁷Division of Hematology/Oncology/BMT, Nationwide Children's Hospital, Columbus, OH

Divyaswathi Citla Sridhar, MD¹, Robert F. Sidonio, Jr., MD, MSc² and Sanjay Ahuja, MD^3,4

¹Arkansas Children's hospital, University of Arkansas for Medical Sciences, Little Rock, AR
²Aflac Cancer and Blood Disorders, Department of Pediatrics, Emory University School of Medicine, Decatur, GA
³Division of Pediatric Hematology & Oncology, Rainbow Babies and Children's Hospital, Cleveland, OH
⁴Case Western Reserve University, Cleveland, OH

Rayli C Pichardo, MD¹, Kashmira Wani^1*, Kathren Shango, MD^2*, Yazan Abu Omar, MD^3* and Philip Kuriakose, MD^4,5

¹Henry Ford Health, Detroit, MI
²Internal Medicine, Henry Ford Hospital, Detroit, MI
³Cleveland Clinic, Cleveland, OH
⁴Henry Ford Cancer Institute, Henry Ford Health System, Detroit, MI
⁵Division of Hematology and Oncology, Henry Ford Hospital/Wayne State University, Detroit, MI

Alok Srivastava¹, Savita Rangarajan, MBBS, MD, FRCP, FRCPath^2,3, Cecil Ross, MBBS, MD^4*, Christina Slota, PhD, RN^5*, Dana DiBenedetti^5*, Viridiana Cano, MD⁶, Shauna Andersson, MD, PhD^6*, Pronabesh Dasmahapatra⁶, José Bartelt-Hofer, PhD^7* and Marion Afonso, MSc^7*

¹Christian Medical College, Vellore, India
²Faculty of Medicine, University of Southampton, Southampton, United Kingdom
³KJ Somaiya Super Specialty Hospital, Mumbai, India
⁴St John’s Medical College Hospital, Bangalore, India
⁵RTI Health Solutions, Research Triangle Park, NC
⁶Sanofi, Cambridge, MA
⁷Sanofi, Chilly-Mazarin, France

Viridiana Cano, MD¹, Carol Mansfield, PhD^2*, Anna Pierce, BBA^2*, Colton Leach, BA^2*, Jane Cavanaugh Smith, BA^1*, Pronabesh DasMahapatra, MD, MPH¹ and José Bartelt-Hofer, PhD^3*

¹Sanofi, Cambridge, MA
²RTI Health Solutions, Research Triangle Park, NC
³Sanofi Genzyme, Chilly-Mazarin, France

Andy Wilson, PhD, MS^1*, Ivana Malenica, PhD^2*, Marc-Aurel Martial, PhD^3*, Cempaka Martial, Mstat^4* and Jackie Vanderpuye-Orgle, PhD^5*

¹Parexel, Highland, UT
²Berkeley, Berkeley, CA
³Brigham Young University, Provo
⁴Intermountain Healthcare, Salt Lake City
⁵Parexel, Billerica, CA

Reena Ravi^1*, Charity I Oyedeji, MD^2,3,4, Richard Faldowski, Ph.D^5*, Stephanie Padrick, BSN, RN^1*, Rania E Mohamed, BS^1*, Arvind Subramaniam, BA, MS^1* and John J. Strouse, MD, PhD^3,6

¹Department of Medicine, Division of Hematology, Duke University, Durham, NC
²Duke Adult Comprehensive Sickle Cell Center, Duke University, Durham, NC
³Department of Medicine, Division of Hematology, Duke University School of Medicine, Durham, NC
⁴Claude D. Pepper Older Americans Independence Center, Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, NC
⁵Center for the Study of Aging and Human Development, Duke University, Durham, NC
⁶Duke Comprehensive Sickle Cell Center, Duke University Medical Center, Durham, NC

Kyaw Zin Thein, MD^1*, Thura Win Htut, MBBS, MRCP^2*, Myat Min Han, MD^3*, Yin Mon Myat, MBBS^4*, Myint Aung Win, MD, MBBS^5*, Ei Moe Phyu, MD^5* and Thein H. Oo, MD, FRCPE, FACP⁶

¹Oregon Health & Science University/ Knight Cancer Institute, PORTLAND, OR
²Hematology department, Aberdeen Royal Infirmary Hospital, Aberdeen, United Kingdom
³Interfaith Medical Center, Brooklyn
⁴University College Dublin, Dublin, Ireland
⁵Internal Medicine, LewisGale Medical Center, Salem, VA
⁶Section of Benign Hematology, The University of Texas MD Anderson Cancer Center, Houston, TX

Shreya Gopal Agrawal, MBBS, MD^1*, Shigy Francis, MBBS, MD^2*, Vijaykumar Narayana Pillai, MBBS, DCH^3*, Manoj Unni, MD DM^4*, Rema Ganapathy, MBBS DNB^5*, Nikhil Krishna Haridas, MBBS, MD, DNB^6*, Chitresh Yadav, MBBS, MD^7*, Rashmi Suresh Yawalkar, MBBS, MD^8*, Sandeep Abhijit Pattnaik, MBBS, MD^6*, Gohul Gopi Jalajakumari,, MBBS, MD^9*, Syamprasad Vinayakumar, Pharm D^6*, Anjusha C^9* and Neeraj Sidharthan, MD, MBBS, DM, DNB¹⁰

¹Clinical Haematology, Amrita institute of Medical sciences, Kochi, India
²Lisie Hospital, Kochi, India
³Hemophilia Treatment Centre Aluva, Kochi, India
⁴Department of Clinical Hematology and Division of Stem Cell Transplantation, Amrita Institute of Medical Sciences, Kochi, India
⁵Department of Clinical Haematology, Amrita Institute of Medical Sciences, Kochi, India
⁶Clinical haematology, Amrita institute of Medical sciences, Kochi, India
⁷Clinical haematology, Amrita institute of Medical sciences, kochi, India
⁸Clinical haematology, AIMS hospital, kochi, India
⁹Amrita institute of Medical sciences, Kochi, India
¹⁰Department of Clinical Hematology and Division of Stem Cell Transplantation, Amrita Institute of Medical Sciences , Amrita University, Kochi, Kerala, India

Udhayvir Singh Grewal, MBBS¹, Sahith Reddy Thotamgari, MD^2*, Shiva Jashwanth Gaddam, MD³, Rachaita Lakra, MD^4* and Usha Perepu, MBBS⁵

¹Division of Hematology, Oncology and Blood and Marrow Transplantation, University of Iowa Hospitals and Clinics, Coralville, IA
²Internal Medicine, Louisiana State University Health Sciences Center, Shreveport, Shreveport, LA
³Hematology and Oncology, Louisiana State University Health Sciences Center, Shreveport, Shreveport, LA
⁴Internal Medicine, Louisiana State University Health Sciences Center Shreveport, Shreveport, LA
⁵Department of Hematology, Oncology, and Blood & Marrow Transplantation, University of Iowa Hospitals and Clinics Program, Iowa City, IA

Stephanie Padrick, BSN, RN^1*, Charity I Oyedeji, MD¹, Arvind Mallikarjunan, MS, BS^2*, Caroline Ezekwesili, MPH^3*, Diamone Gathers^4* and John J. Strouse, MD, PhD⁵

¹Department of Medicine, Division of Hematology, Duke University, Durham, NC
²Department of Medicine, Division of Hematology - Duke Sickle Cell Comprehensive Care Unit, Duke University Hospital, Durham, NC
³Florida International University Herbert Wertheim College of Medicine, Miami, FL
⁴Duke University Medical Center, Durham
⁵Department of Medicine, Division of Hematology, Duke University School of Medicine, Durham, NC

Sara Guasch Parks, MD^1*, Stacey Fedewa, PhD, MPH^2*, Tyler W Buckner, MD, MSc³, Ana G Antun, MD⁴, Lorraine Cafuir, MD^2,5, Duc Q Tran Jr., MD, MSc^6,7, Shanna Mattis, MPH^8* and Christine L Kempton, MD, MSc⁹

¹Carilion Clinic, Roanoke, VA
²Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA
³University of Colorado, Aurora, CO
⁴Emory University, Decatur, GA
⁵Emory University Winship Cancer Institute, Atlanta, GA
⁶Department of Hematology & Medical Oncology, Emory University School of Medicine, Atlanta, GA
⁷Department of Hematology and Medical Oncology, Hemophilia of Georgia Center for Bleeding & Clotting Disorders of Emory, Emory University School of Medicine, ATLANTA, GA
⁸Hemophilia of Georgia Center for Bleeding & Clotting Disorders of Emory, Emory University School of Medicine, Atlanta, GA
⁹Hemophilia of Georgia Center for Bleeding & Clotting Disorders of Emory, Emory University, Atlanta, GA

Sophia Xin Wen, MD¹, Rosane Nisenbaum, PhD^2,3*, Michael Auerbach, MD⁴ and Michelle Sholzberg, MD^5,6

¹Department of Medicine, University of Toronto, Toronto, ON, Canada
²Li Ka Shing Knowledge Institute, Centre for Urban Health Solutions, St. Michael's Hospital, Toronto, ON, Canada
³Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada
⁴Department of Medicine, Georgetown University School of Medicine, Washington, DC
⁵Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, ON, Canada
⁶Department of Laboratory Medicine and Pathobiology, St. Michael's Hospital, Toronto, Canada

Anna Legassie, BA^*, Felice Tsui, MPH^* and Michele Rhee, MBA, MPH^*

X4 Pharmaceuticals, Inc., Boston, MA

Jennifer M Jones, MD¹, Julia Wool, BS^2*, Elizabeth P Crowe, MD, PhD^3*, Evan Bloch, MD, MS^4*, Lydia H. Pecker, MD⁵ and Sophie M. Lanzkron, MD⁶

¹Department of Medicine, Division of Hematology, Johns Hopkins Medicine, Baltimore, MD
²Division of Hematology, Johns Hopkins University, Baltimore, MD
³Johns Hopkins University, Baltimore, MD
⁴Division of Transfusion Medicine, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD
⁵Division of Hematology, Department of Medicine, Johns Hopkins Hospital, Baltimore, MD
⁶Division of Hematology, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD

Sophie M. Lanzkron, MD¹, Jane Alison Little, MD², Daniel Semakula, MBChB, PhD^3*, Jessica Liang^4*, Sara Stuart-Smith^5*, Rachel Kesse-Adu, MBBS^6*, Julie Kanter, MD⁷, Alice J. Cohen, MD⁸, Sana Saif Ur Rehman, MD^9*, Stephanie H Guarino, MD¹⁰, Deepa Manwani, MD¹¹, Payal C Desai, MD¹² and Kate Gardner, MD., PhD^13*

¹Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD
²Department of Medicine, UNC Adult Sickle Cell Program, Chapel Hill, NC
³Hematology, Johns Hopkins School of Medicine, Baltimore, MD
⁴Hematology, Johns Hopkins School of Medicine, Balitmore, MD
⁵King's College Hospital, London, GBR
⁶Guy's and St. Thomas' Hospital, London, GBR
⁷Director, Adult Sickle Cell Program, University of Alabama at Birmingham, Birmingham, AL
⁸Division of Hematology/Oncology, Newark Beth Israel Med. Ctr., Newark, NJ
⁹Division of Hematology, Washington University School of Medicine, Saint Louis, MO
¹⁰Center for Special Health Care Needs/Institute on Research in Equity and Community Health, ChristianaCare, Newark, DE
¹¹Division of Pediatric Hematology/Oncology, Department of Pediatrics, Children's Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, NY
¹²Levine Cancer Institute, Charlotte, NC
¹³Department of Haematology, Guy and St Thomas’ NHS Foundation Trust, London, United Kingdom