Srdan Verstovsek, MD, PhD¹, Stephen T Oh, MD, PhD², Jean-Jacques Kiladjian, MD³, Uwe Platzbecker, MD⁴, Francesco Passamonti, MD^5*, Aaron T. Gerds, MD, MS⁶, Alessandro M Vannucchi, MD⁷, Donal P. McLornan, MD, PhD^8*, Vikas Gupta, MD, FRCP, FRCPath⁹, Sebastian Grosicki, MD, PhD¹⁰, Haifa Kathrin Al-Ali, MD^11*, David Lavie, MD^12*, Andrew Kuykendall, MD¹³, Sung-Eun Lee, MD^14*, Alessandra Iurlo, MD, PhD^15*, Luminita Ocroteala, MD^16*, Jun Kawashima, MD^17*, Rafe Donahue, PhD^17*, Bryan Strouse, MSc^17* and Ruben Mesa, MD, FACP¹⁸

¹Leukemia Department, The University of Texas MD Anderson Cancer Center, Houston, TX
²Siteman Cancer Center, Washington University School of Medicine, Saint Louis, MO
³Université de Paris, AP-HP, Hôpital Saint-Louis, Centre d’Investigations Cliniques, Paris, France
⁴Department for Hematology, Cell Therapy and Hemostaseology, University of Leipzig Medical Center, Leipzig, Germany
⁵University of Insubria, Varese, Italy
⁶Department of Hematology and Medical Oncology,, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH
⁷University of Florence, Firenze, Italy
⁸Haematology Department, Guy's and St Thomas' NHS Trust, London, United Kingdom
⁹Division of Medical Oncology and Hematology, University Health Network, Toronto, ON, Canada
¹⁰Medical University of Silesia, Katowice, Poland
¹¹University Hospital of Halle, Halle, Germany
¹²Hadassah-Hebrew University Medical Centre, Jerusalem, Israel
¹³Department of Malignant Hematology, H. Lee Mofitt Cancer Center, Tampa, FL
¹⁴Department of Hematology, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Houston, TX
¹⁵Hematology Division, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy
¹⁶Filantropia Hospital, Craiova, Romania
¹⁷Sierra Oncology Inc., San Mateo, CA
¹⁸UT Health San Antonio Cancer Center, San Antonio, TX

Anders Lindholm Lindholm Sørensen, MD^1*, Vibe Skov, PhD^1*, Lasse Kjær, PhD^1*, Christina Schjellerup Schjellerup Eickhardt-Dalbøge, MD^2*, Morten Kranker Larsen, MSc^1*, Claus Nielsen^3*, Carsten Thomsen^4*, Lise Mette Rahbek Gjerdrum, MD, PhD^5*, Trine Alma Knudsen^1*, Christina Ellervik, PhD^6,7,8,9*, Ulrik Malthe Overgaard, MD^10*, Christen Lykkegaard Andersen, MD^11*, Mads Emil Bjørn, MD^12* and Hans Carl Hasselbalch, MD¹

¹Department of Hematology, Zealand University Hospital, Roskilde, Denmark
²Department of Haematology, Zealand University Hospital, Roskilde, Roskilde, Denmark
³Copenhagen University Hospital Rigshospitalet, Copenhagen Ø, DNK
⁴Zealand University Hospital, Roskilde, DNK
⁵Department of Pathology, Zealand University Hospital, Roskilde, Denmark
⁶Department of Production, Research, and Innovation, Region Zealand, Sorø, MA, Denmark
⁷Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
⁸Department of Laboratory Medicine, Boston Children's Hospital, Boston, MA
⁹Department of Pathology, Harvard Medical School, Boston, MA
¹⁰Department of Hematology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
¹¹Copenhagen University Hospital, Rigshospitalet, Copenhagen, DNK
¹²Department of Hematology, Zealand University Hospital, Roskilde, DNK

Orly Leiva, MD¹, Chi-Joan How, MD^2,3, Andrew M. Brunner, MD⁴ and Gabriela S. Hobbs, MD⁵

¹Division of Cardiovascular Medicine, Department of Medicine, New York University Grossman School of Medicine, New York City, NY
²Internal Medicine - Hematology, Brigham and Women's Hospital, Somerville, MA
³Dana Farber Cancer Institute / Massachusetts General Hospital, Boston, MA
⁴Hematology-Oncology, Massachusetts General Hospital, Boston, MA
⁵Cancer Center, Massachusetts General Hospital, Boston, MA

Aaron T. Gerds, MD, MS¹, Michael R. Grunwald, MD², Stephen T. Oh, MD, PhD^3*, Evan Braunstein, MD, PhD^4*, Zhenyi Xue, PhD^4*, Valkal Bhatt, PharmD^4*, Jingbo Yu, MD, PhD⁴ and Ruben Mesa, MD, FACP⁵

¹Cleveland Clinic Taussig Cancer Institute, Cleveland, OH
²Department of Hematologic Oncology and Blood Disorders, Levine Cancer Institute, Atrium Health, Charlotte, NC
³Washington University School of Medicine, St. Louis, MO
⁴Incyte Corporation, Wilmington, DE
⁵UT Health San Antonio MD Anderson Cancer Center, San Antonio, TX

Daniel Kristensen, MD^1,2*, Andreas K. Oevlisen, MD^1*, Lasse Hjort Jakobsen, MSc, PhD^2,3*, Marianne Tang Severinsen, MD, PhD^1,2*, Tarec Christoffer Christoffer El-Galaly, MD, DSc^1,2 and Anne Stidsholt Roug, MD, PhD^1,2,4*

¹Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
²Department of Hematology, Clinical Cancer Research Center, Aalborg University Hospital, Aalborg, Denmark
³Department of Mathematical Science, Aalborg University, Aalborg, Denmark
⁴Department of Hematology, Aarhus University Hospital, Aarhus, Denmark

Tiziano Barbui, MD^1*, Alessandra Carobbio, MSc^1*, Arianna Ghirardi, PhD^1*, Alessandra Iurlo, MD, PhD^2*, Valerio De Stefano, MD^3*, Marta Anna Sobas, MD, PhD^4*, Elisa Rumi, MD^5*, Elena Maria Elli, MD^6*, Francesca Lunghi, MD^7*, Mercedes Gasior Kabat, MD^8*, Beatriz Cuevas, MD^9*, Paola Guglielmelli, MD, PhD¹⁰, Massimiliano Bonifacio, MD^11*, Monia Marchetti^12*, Alberto Alvarez-Larran, MD, PhD^13*, Laura Maria Fox, MD^14*, Marta Bellini, MD^15*, Rosa Daffini, MD^16*, Giulia Benevolo, MD^17*, Gonzalo Carreño, MD PhD^18*, Andrea Patriarca, MD^19*, Haifa Kathrin Al-Ali, MD^20*, Marcio Andrade, MD, PhD^21*, Francesca Palandri, PhD, MD^22*, Claire N. Harrison, DM²³, Maria Angeles Foncillas, MD^24*, Santiago Osorio, MD^25*, Steffen Koschmieder²⁶, Elena Magro, MD^27*, Jean-Jacques Kiladjian, MD²⁸, Estefanía Bolaños, MD^29*, Florian H. Heidel, MD³⁰, Keina Quiroz, MD^31*, Martin Griesshammer^32*, Valentín García Gutiérrez, PhD³³, Alberto Marin Sanchez, MD^34*, Juan Carlos Hernandez Boluda, MD, PhD^35*, Emma Lopez Abadia, MD^36*, Giuseppe Carli, MD^37*, Miguel Sagüés, MD^38*, Rajko Kusec, MD, PhD^39*, Blanca Xicoy, MD^40*, Margarita Guenova, PhD^41*, Begoña Navas, MD^42*, Anna Angona, MD^43*, Edyta Cichocka, MD^44*, Anna Masternak, MD^45*, Daniele Cattaneo, MD^2,46*, Cristina Bucelli, MD^47*, Silvia Betti, MD, PhD^3*, Oscar Borsani, MD⁵, Fabrizio Cavalca^48*, Sara Carbonell, MD^13*, Natalia Curto-Garcia, MD^23*, Lina Benajiba, MD, PhD^49*, Alessandro Rambaldi, MD^15,46 and Alessandro M. Vannucchi¹⁰

¹FROM Research Foundation Ospedale di Bergamo, Bergamo, Italy
²Hematology Division, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy
³Section of Hematology, Catholic University, Fondazione Policlinico "A. Gemelli" IRCCS, Rome, Italy
⁴Department of Hematology, Blood Neoplasms and Bone Marrow Transplantation, Wroclaw Medical University, Wroclaw, Poland
⁵Department of Molecular Medicine, University of Pavia, Pavia, Italy
⁶San Gerardo Hospital, ASST Monza, Monza, Italy
⁷Department of Onco-Haematology - Haematology and Bone Marrow Transplantation, IRCCS San Raffaele Scientific Institute and Vita-Salute Hospital, Milano, Italy
⁸Hospital Universitario La Paz, Madrid, ESP
⁹Hematology, Hospital Universitario de Burgos, BURGOS, ESP
¹⁰CRIMM, Center for Research and Innovation of Myeloproliferative Neoplasms, AOU Careggi, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy
¹¹Department of Medicine, Section of Hematology, University of Verona and Azienda Ospedaliera Universitaria Integrata, Verona, Italy
¹²Division of Hematology, Hospital Antonio e Biagio and Cesare Arrigo, Alessandria, Italy
¹³Hematology Department, Hospital Clínic, Barcelona, Spain
¹⁴Department of hematology, Vall d’Hebron Institute of Oncology (VHIO), Vall d’Hebron Hospital Universitari, Barcelona, Spain
¹⁵Department of Oncology-Hematology, Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Italy
¹⁶Department of Hematology, ASST Spedali Civili, Brescia, Italy
¹⁷Division of Hematology, AOU "Città della Salute e della Scienza di Torino", Turin, Italy
¹⁸Hematology Department, Hospital Universitario 12 de Octubre, Instituto de Investigación Sanitaria Imas12, Madrid, Spain
¹⁹Hematology Unit, Department of Translational Medicine, University of Eastern Piedmont and AOU Maggiore della Carità, Novara, Italy
²⁰Krukenberg Cancer Center Halle, University Hospital Halle (Saale), Halle/ Saale, Germany
²¹Hematology Department, Hospital del Mar, Barcelona, Spain
²²IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia "Seràgnoli", Bologna, Italy
²³Guy’s and St Thomas’ NHS Foundation Trust, London, United Kingdom
²⁴Hospital Universitario Infanta Leonor, Madrid, Spain
²⁵Hospital General U. Gregorio Marañón, Madrid, Spain
²⁶Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Faculty of Medicine, University Hospital of Aachen, Aachen, Germany
²⁷Hospital Universitario Principe de Asturias, Alcalá de Henares, Spain
²⁸Hopital Saint-Louis, Paris, France
²⁹Hospital Clinico San Carlos, Madrid, Spain
³⁰Innere Medicin C, Universitätsmedizin Greifswald, Greifswald, Germany
³¹Hospital Universitario de Móstoles, Madrid, Spain
³²University Clinic for Hematology, Oncology, Haemostaseology and Palliative Care, Johannes Wesling Medical Center, Minden, University of Bochum, Minden, Germany
³³Hematology Service, Hospital Universitario Ramón y Cajal. IRYCIS, Madrid, Spain
³⁴Hospital General Universitario De Albacete, Albacete, ESP
³⁵Department of Hematology, Hospital Clínico Universitario de Valencia, Instituto de Investigación Sanitaria INCLIVA, Valencia, Spain
³⁶Hospital General De Elche, Elche, Alicante, Spain
³⁷Department of Hematology, S. Bortolo Hospital, Vicenza, Vicenza, Italy
³⁸Hospital de Sant Joan Despí Moisès Broggi, Sant Joan Despí, Barcelona, Spain
³⁹Department of haematology, Clinic of internal medicine, University Hospital Dubrava-School of Medicine University of Zagreb, Zagreb, Croatia
⁴⁰HU German Trias i Pujol - Institut Català d' Oncologia, Barcelona, Spain
⁴¹Laboratory of Hematopathology & Immunology, National Specialised Hospital for Active Treatment of Hematological Diseases, Sofia, BGR
⁴²Hematology and hemotherapy department, Hospital Universitario HLA Moncloa, Madrid, Spain
⁴³HU Dr. J Trueta - Institut Català d'Oncologia, Girona, Spain
⁴⁴Department of Hematology and Bone Marrow Transplantation, Copernicus Memorial Hospital, Torun, Poland
⁴⁵Department of Hematology and Hematooncology, District Specialist Hospital, Opole, Opole, Poland
⁴⁶University of Milan, Milan, Italy
⁴⁷Hematology Division, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy
⁴⁸Hematology Division and Bone Marrow Transplant Unit, San Gerardo Hospital, ASST Monza, Monza, Italy
⁴⁹Hôpital Saint-Louis, Université de Paris, Paris, France

Ghaith Abu-Zeinah, MD¹, Franco Castillo Tokumori, MD², Katie Erdos^1*, Imane Bouhali^3*, Daniel C Choi, MD¹, Richard T. Silver, MD¹ and Joseph Scandura, MD, PhD¹

¹Richard T. Silver, M.D. Myeloproliferative Neoplasms (MPN) Center, Weill Cornell Medicine, New York, NY
²NewYork Presbyterian Hospital/ Weill Cornell, New York, NY
³Weill Cornell Medicine - Qatar, Doha, Qatar

Naveen Pemmaraju, MD¹, Krishna Gundabolu, MBBS², Jack Snyder, MD, JD, PhD, MBA^3*, Michael H Silverman, MD, FACP^4*, Geraldine Bardelli, MT(ASCP)^5*, Srdan Verstovsek, MD, PhD⁶ and Gary J. Schiller, MD⁷

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Division of Hematology & Oncology, Department of Internal Medicine, University of Nebraska Medical Center- Fred and Pamela Buffett Cancer Center, Omaha, NE
³, NC 27513, Allucent, Cary, NC
⁴Samus Therapeutics Inc., Marblehead, MA
⁵Samus Therapeutics Inc., Cheshire, CT
⁶Leukemia Department, The University of Texas MD Anderson Cancer Center, Houston, TX
⁷David Geffen School of Medicine at UCLA, Los Angeles, CA

Srdan Verstovsek, MD, PhD¹, Florian H. Heidel^2*, Valerio De Stefano, MD^3*, Mike Zuurman, PhD^4*, Kenneth Bryan, PhD^5*, Armita Afsharinejad, PhD^5* and Jean-Jacques Kiladjian, MD⁶

¹Leukemia Department, The University of Texas MD Anderson Cancer Center, Houston, TX
²Hematology, Oncology, Stem Cell Transplantation and Palliative Care, Internal Medicine C, University Medicine Greifswald, Greifswald, Germany
³Sezione di Ematologia, Dipartimento di Scienze Radiologiche ed Ematologiche, Università Cattolica, Roma, Italy
⁴Novartis Pharma AG, Basel, Switzerland
⁵Novartis Ireland Limited, Dublin, Ireland
⁶Université de Paris, AP-HP, Hôpital Saint-Louis, Centre d’Investigations Cliniques, INSERM, CIC1427, Paris, France

John Mascarenhas, MD¹, Claire N. Harrison, DM², Jean-Jacques Kiladjian, MD³, Rami S. Komrokji⁴, Steffen Koschmieder⁵, Alessandro M. Vannucchi⁶, Tymara Berry, MD^7*, Denise Redding^7*, Laurie Sherman, BSN⁷, Souria Dougherty, BS, MBA^7*, Lixian Peng, PhD^7*, Libo Sun, PhD^7*, Fei Huang, PhD⁷, Ying Wan, PhD^7*, Faye Feller, MD⁷ and Srdan Verstovsek, MD, PhD⁸

¹Department of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY
²Guy's and St Thomas' NHS Foundation Trust, London, ENG, United Kingdom
³Hopital Saint-Louis, Paris, France
⁴Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL
⁵Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Faculty of Medicine, University Hospital of Aachen, Aachen, Germany
⁶CRIMM, Center Research and Innovation of Myeloproliferative Neoplasms, University of Florence, AOU Careggi, Florence, Italy
⁷Geron Corporation, Parsippany, NJ
⁸Leukemia Department, The University of Texas MD Anderson Cancer Center, Houston, TX

Oscar Borsani, MD^1,2, Virginia Valeria Ferretti, PhD^3*, Ilaria Carola Casetti, MD, PhD^1*, Daniele Vanni, MD^1*, Chiara Trotti, MD^1*, Martina Boldini, MD^1*, Daniela Pietra, PhD^2*, Annalisa De Silvestri, MSc^3*, Luca Arcaini^1,2* and Elisa Rumi^2,4*

¹Department of Molecular Medicine, University of Pavia, Pavia, Italy
²Division of Hematology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
³Service of Clinical Epidemiology and Biometry, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
⁴Department of Molecular Medicine, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy

Rami S. Komrokji¹, Michael R. Grunwald, MD², Evan Braunstein, MD, PhD^3*, J.E. Hamer-Maansson, MSPH^3*, Patricia Kalafut, PhD^3* and John Mascarenhas, MD⁴

¹Malignant Hematology Department, H. Lee Moffitt Cancer Center and Research, Tampa, FL
²Department of Hematologic Oncology and Blood Disorders, Levine Cancer Institute, Atrium Health, Charlotte, NC
³Incyte Corporation, Wilmington, DE
⁴Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY

Naveen Pemmaraju, MD¹, Srdan Verstovsek, MD, PhD¹, Marina Kremyanskaya, MD, PhD², Frank Valone, MD^3*, Nishit B. Modi, PhD^3*, Sarita Khanna, PhD^3*, Paula G. O'Connor, MD^3*, Suneel K. Gupta, PhD³ and Ronald Hoffman, MD⁴

¹MD Anderson Cancer Center, University of Texas, Houston, TX
²Tisch Cancer Institute, Division of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY
³Protagonist Therapeutics, Inc, Newark, CA
⁴Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY

Cem Akin, MD, PhD^1*, Frank Siebenhaar, PD Dr. med^2*, Michael W. Deininger, MD, PhD³, Daniel J. DeAngelo, MD, PhD^4*, Tracy I. George, MD⁵, Mariana Castells, MD, PhD^6*, Matthew Giannetti, MD^7*, Jason Gotlib, MD, MS⁸, Jessica Sachs, MD⁹, Amanda Pilla^9*, Hina A. Jolin, PharmD^9* and Prithviraj Bose, MD¹⁰

¹University of Michigan, Ann Arbor, MI
²Corporate Member of Freie Universität Berlin, Humboldt - Universität zu Berlin, Dermatological Allergology, Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, Germany
³Versiti Blood Research Institute, Milwaukee, WI
⁴Dana-Farber Cancer Institute, Boston, MA
⁵ARUP Laboratories, Salt Lake City, UT
⁶Department of Medicine, Division of Allergy and Clinical Immunology, Brigham and Women’s Hospital, Boston, MA
⁷Department of Medicine, Brigham and Women’s Hospital, Boston, MA
⁸Department of Hematology, Stanford Cancer Institute/Stanford University School of Medicine, San Carlos, CA
⁹Cogent Biosciences, Inc., Cambridge, MA
¹⁰MD Anderson Cancer Center, Houston, TX

Chiara Paoli, PhD^1*, Paola Guglielmelli, MD, PhD¹, Francesco Mannelli, MD^1*, Miriam Borella, RN^1*, Vittorio Rosti, MD², Elisa Rumi^3*, Maria Chiara Finazzi^4*, Oscar Borsani, MD⁵, Carmela Mannarelli, PhD^1*, Maria Esposito, BiSc^1*, Mario Xhani, BiSc^1*, Lisa Pieri, MD, PhD^6*, Tiziano Barbui, MD^7*, Alessandro Rambaldi, MD⁸ and Alessandro Vannucchi, MD¹

¹CRIMM, Center Research and Innovation of Myeloproliferative Neoplasms, University of Florence, AOU Careggi, Florence, Italy
²Center for the Study of Myelofibrosis, Laboratory of Biochemistry Biotechnology and Advanced Diagnosis, IRCCS Policlinico San Matteo, Pavia, PV, Italy
³Department of Molecular Medicine, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
⁴Department of Oncology and Hematology University of Milan and Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Italy
⁵Department of Molecular Medicine, University of Pavia, Pavia, Italy
⁶AOU Careggi, Center Hemorrhagic Diseases, Florence, Italy
⁷FROM Research Foundation Bergamo, Bergamo, Italy
⁸Hematology, ASST Papa Giovanni XXIII, Bergamo, Italy

Morten Kranker Kranker Larsen, MSc^1,2*, Vibe Skov, PhD^1*, Lasse Kjær, PhD^1*, Henrik E. Poulsen, PhD^2,3,4*, Christina S. Eickhardt-Dalbøge, MD^1,2*, Trine A. Knudsen, MD^1,2*, Sarah F. Christensen, PhD^1*, Anders L. Sørensen, PhD^1*, Marie H. Kristiansen, MD^2,5*, Troels Wienecke, PhD^2,5*, Rasmus K. Pedersen, PhD^6*, Morten Andersen, PhD^6*, Johnny T. Ottesen, PhD^6*, Thomas Stiehl, PhD^6,7*, Christina Ellervik, PhD^2,8,9* and Hans Carl Hasselbalch, MD^1,2

¹Department of Hematology, Zealand University Hospital, Roskilde, Denmark
²Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
³Department of Endocrinology, Copenhagen University Hospital, Bispebjerg Frederiksberg Hospital, Copenhagen, Denmark
⁴Department of Cardiology, Copenhagen University Hospital, Nordsjællands Hospital, Hillerød, Denmark
⁵Department of Neurology, Zealand University Hospital, Roskilde, Denmark
⁶Department of Science and Environment, Roskilde University, Roskilde, Denmark
⁷Institute for Computational Medicine - Disease Modeling, RWTH Aachen University Hospital, Aachen, Germany
⁸Department of Production, Research, and Innovation, Region Zealand, Sorø, Denmark
⁹Department of Pathology, Harvard Medical School, Boston, MA

Jan Philipp Bewersdorf, MD¹, Srdan Verstovsek, MD, PhD², Andriy Derkach, PhD^3*, Lucia Masarova, MD⁴, Naveen Pemmaraju, MD⁴, Eytan Stein, MD⁵, Michael Mauro, MD⁵, Raajit K Rampal, MD, PhD⁶ and Prithviraj Bose, MD⁷

¹Department of Medicine; Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY
²Leukemia Department, The University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Biostatistics and Epidemiology, Memorial Sloan Kettering Cancer Center, New York, NY
⁴Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
⁵Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
⁶Department of Medicine, Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY
⁷The University of Texas MD Anderson Cancer Center, Houston, TX

Laurence Legros, PhD, MD^1,2*, Françoise Boyer perrard^3*, Dana Ranta, MD^4*, Lydia Roy, MD^5,6*, Mario Ojeda-Uribe^7*, Stephane Giraudier, MD, PhD^8,9*, Nathalie Parquet, MD^10*, Jean Christophe Ianotto, MD, PhD^11*, Mathieu Wemeau, MD^12,13*, Isabelle Plantier, MD^14*, Franck E. Nicolini, MD, PhD¹⁵, Eric Lippert, MD, PhD^13*, Pascale Cony-Makhoul, MD^16*, Fiorenza Barraco, MD^17*, Laure Stalnikiewicz^18*, Frederic Garban^19*, Brigitte Dupriez, MD, PhD¹³, Francois Girodon, MD, PhD ¹³, Anne Brignier, MD^10*, Yazid Arkam, MD^20*, Mathieu Meunier^21*, Chloe James, MD, PhD^13,22*, Valérie Rolland-Neyret^23*, Valerie Ugo, MD, PhD^13,24, Pierre Morel, MD^25*, Marie C Bene, PharmD, DPhil^26* and Jean-Jacques Kiladjian, MD^27,28

¹France Intergroupe des Néoplasies Myéloprolifératives, FIM collaborative group, Paris, France
²Department of clinical Hematology, APHP-Université Paris Saclay-Hôpital Bicêtre, Kremlin-Bicêtre, France
³Service des maladies du sang, Centre Hospitalier Universitaire d’Angers, Angers, France
⁴Centre Hospitalier Universitaire, Nancy, France
⁵Hematology department, Hopital Henri Mondor, Creteil, France
⁶FIM, paris, France
⁷Department of Hematology and Cellular Therapy, GHRMSA, Mulhouse, France
⁸INSERM UMR 1131, Saint-Louis Research Institute, Paris, France
⁹Université de Paris, Cellular biology Department, Saint-Louis hospital, APHP, Paris, France
¹⁰Therapeutic Apheresis Unit, Saint Louis Hospital, Paris, France
¹¹Department of Hematology, CHU de Brest, Brest, FRA
¹²CHR de Roubaix, Roubaix, FRA
¹³France Intergroupe des Néoplasies Myéloprolifratives, FIM collaborative group, Paris, France
¹⁴Service d'hématologie clinique, CH Roubaix, Roubaix, France
¹⁵Hematology department & CRCL1052, Centre Léon Bérard, Lyon, France
¹⁶Service d'Hématologie, Centre Hospitalier Annecy-Genevois, Pringy, France
¹⁷Department of Hematology, Centre Hospitalier Lyon Sud, Pierre Bénite, France
¹⁸Centre hospitalier Lens, lens, French Southern Territories
¹⁹Department of Hematology, CHU Grenoble Alpes, Grenoble, France
²⁰Service d'hématologie, GHR Mulhouse Sud Alsace, mulhouse, France
²¹Department of Hematology, CHU de Grenoble, La Tronche, FRA
²²Unite INSERM U1034, Pessac, FRA
²³CHU de Grenoble, Grenoble, France
²⁴Hematology Biology, Angers University Hospital, Angers, France
²⁵Service d’Hématologie Clinique et de Thérapie Cellulaire, CHU Amiens, Salouel, France
²⁶Hematology Biology, Nantes University Hospital, Nantes, France
²⁷French Intergroup of Myeloproliferative neoplasms, FIM collaborative group, Paris, France
²⁸Centre d’Investigations Cliniques, Hôpital Saint-Louis, Paris, France

Sung-Eun Lee, MD^1*, Sung-Soo Yoon, MD, PhD², Deok-Hwan Yang^3*, Gyeong-Won Lee^4*, Seug Yun Yoon^5*, Sang Kyun Sohn^6*, Ho-Jin Shin^7*, Sung Hwa Bae^8*, Chul Won Choi^9*, Eun-Ji Choi, MD, PhD¹⁰, June-Won Cheong¹¹, Soo-Mee Bang, MD, PhD¹² and Joon Seong Park^13*

¹Department of Hematology, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Houston, TX
²Division of Hematology/Medical Oncology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of (South)
³Department of Hematology-Oncology, Chonnam National University Hwasun Hospital, Jeollanam-do, Korea, Republic of (South)
⁴Department of Internal Medicine, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, KOR
⁵Division of Hematology & Medical Oncology, Department of Internal Medicine, Soonchunhyang University Seoul Hospital, Seoul, New Jersey, Korea, Republic of (South)
⁶Department of Hematology–Oncology, Kyungpook National University Hospital, Daegu, Korea, Republic of (South)
⁷Division of Hematology-Oncology, Department of Internal Medicine, Pusan National University Hospital, Pusan National University School of Medicine, Pusan, Korea, Republic of (South)
⁸Department of Hematology/Oncology, Daegu Catholic Univ. Medical Center, Daegu, Korea, Republic of (South)
⁹Divison of Hematology-Oncology, Department of Internal Medicine, Korea University College of Medicine, Guro Hospital, Seoul, Korea, Republic of (South)
¹⁰Department of Hematology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
¹¹Division of Hematology, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of (South)
¹²Division of Hemato-Oncology, Department of Internal medicine, Seoul National University Bundang Hospital, Seongnam-si, South Korea
¹³Department of Hematology-Oncology, Ajou University School of Medicine, Suwon, Korea, Republic of (South)

Joan How, MD¹, Kathleen M.E. Gallagher, PhD^2*, Yiwen Liu^3*, Katelin Katsis^4*, Eva Elder^5*, Donna S. Neuberg, ScD³, Patrick M. Reeves, PhD^6*, Marcela V. Maus, MD⁷ and Gabriela S. Hobbs, MD⁷

¹Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA
²Cellular Immunotherapy Program, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA
³Department of Data Science, Dana-Farber Cancer Institute, Boston, MA
⁴Massachusetts General Hospital, Boston, MA
⁵Massachusetts General Hospital, Harvard Medical School, Charlestown, MA
⁶Vaccine and Immunotherapy Center, Massachusetts General Hospital, Boston, MA
⁷Cancer Center, Massachusetts General Hospital, Boston, MA

Shreekant Parasuraman, BPharm, PhD^1*, Anna Teschemaker, PhD^1*, Jonathan K. Kish, PhD, MPH^2*, Kristin M. Savill, PhD^2* and Philomena Colucci, DO, MS^1*

¹Incyte Corporation, Wilmington, DE
²Cardinal Health Specialty Solutions, Dublin, OH

Anna Ravn Landtblom, MD^1,2*, Therese M.L. Andersson, PhD^3*, Anna L.V. Johansson, PhD^3,4*, Frida E. Lundberg, PhD^3*, Jan Samuelsson, MD, PhD⁵, Magnus Björkholm, MD, PhD² and Malin Hultcrantz, MD, PhD^2,6

¹Department of Hematology, Karolinska University Hospital, Stockholm, Sweden
²Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden
³Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
⁴Cancer Registry of Norway, Oslo, Norway
⁵Department of Hematology, Linköping University Hospital, Linkoping, Sweden
⁶Myeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY

Jie Jin, PhD¹, Lei Zhang, MD, PhD^2*, Zonghong Shao³, Jie Bai, MD³, Suning Chen, MD, PhD^4*, Minghui Duan^5*, Sujiang Zhang, MD, PhD^6*, Hu Zhou, MD, PhD^7*, Na Xu, MD, PhD^8*, Xin Du^9*, Xuelan Zuo, MD, PhD^10*, Li Wang, MD, PhD^11*, Pei Li, MD, PhD^12*, Xuhan Zhang, MD, PhD^13*, Daoxiang Wu^14*, Yaning Li^15*, Jingjing Zhang^15*, Wei Wang^15*, Warren Shen^15*, Oleh Zagrijtschuk, MD^16*, Raymond Urbanski, MD, PhD^16*, Toshiaki Sato, MD, PhD^17*, Albert Qin, MD, PhD^16* and Zhijian Xiao, MD&PhD^18*

¹Department of Hematology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
²State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences, Tianjin, China
³Department of Hematology, The Second Hospital of Tianjin Medical University, Tianjin, China
⁴Jiangsu Institute of Hematology, National Clinical Research Center for Hematologic Diseases, NHC Key Laboratory of Thrombosis and Hemostasis, The First Affiliated Hospital of Soochow University, Suzhou, China
⁵Department of Hematology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, Beijing, China
⁶Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
⁷Department of Hematology, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital，Hemostasis and Thrombosis Diagnostic Engineering Research Center of Henan Province, Zhengzhou, China
⁸Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China
⁹Department of Hematology, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, CA, China
¹⁰Department of Hematology,, Zhongnan Hospital of Wuhan University, Wuhan, China
¹¹The First Affiliated Hospital of Chongqing Medical University, Chongqing, China
¹²Huashan Hospital Affiliated to Fudan University, Shanghai, China
¹³The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China
¹⁴PharmaEssentia Biotech (Beijing) Limited, BeiJing, China
¹⁵PharmaEssentia Biotech (Beijing) Limited, Beijing, China
¹⁶PharmaEssentia U.S.A. Corp., Burlington, MA
¹⁷PharmaEssentia Japan KK, Tokyo, Japan
¹⁸Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China

Anand Ashwin Patel, MD¹, James J. Yoon, MD², Hannah Johnston, MD^3*, Evan C. Chen^4*, Madelyn Burkart, MD⁵, Timothy Seijung Oh, MD^6*, Sunil G. Iyer, MD^7*, Ellen Madarang, PharmD^7*, Iyana Gross^8*, Terrence Bradley, MD⁷, Yasmin Abaza, MD⁹, Jacqueline S. Garcia, MD¹⁰, Rory M. Shallis, MD¹¹, Guru Subramanian Guru Murthy, MD^12*, Vikas Gupta, MD, FRCP, FRCPath¹³, Kristen M. Pettit¹⁴, John Cursio, PhD^8* and Olatoyosi Odenike, MD¹⁵

¹Department of Medicine, Section of Hematology/Oncology, University of Chicago Medical Center, Chicago, IL
²Division of Hematology/Oncology, Department of Medicine, University of Michigan, Ann Arbor, MI
³Department of Medicine, The University of Chicago, Chicago, IL
⁴Dana-Farber Cancer Institute, Boston, MA
⁵Department of Medicine, Division of Hematology/Oncology and the Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Northwestern University Feinberg School of Medicine, Chicago, IL
⁶Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL
⁷University of Miami, Sylvester Comprehensive Cancer Center, Miami, FL
⁸University of Chicago Comprehensive Cancer Center, Chicago, IL
⁹Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL
¹⁰Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
¹¹Department of Internal Medicine, Section of Hematology, Yale University School of Medicine, New Haven, CT
¹²Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI
¹³Princess Margaret Cancer Centre, Division of Medical Oncology and Hematology, University Health Network, University of Toronto, Toronto, ON, Canada
¹⁴Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI
¹⁵Department of Medicine, Section of Hematology/Oncology, University of Chicago, Chicago, IL

Astrid Wintering^1*, Anna Hecht, MD^2*, Julia Meyer, PhD^3*, Eric Brandon Wong, BA^3*, Deborah L French, PhD⁴, Jean Ann Maguire, PhD^4*, Chintan Jobaliya, MS^4*, Marta Rojas Vasquez, MD, FRCPC^5*, Sunil J. Desai, MRCP, FRCPC, BM, BCh⁵, Robin Yates Dulman, MD⁶, Eneida R. Nemecek, MD, MBA, MSc⁷, Farid F Chehab, PhD^8*, Mignon L. Loh, MD⁹ and Elliot Stieglitz, MD¹⁰

¹Department of Pediatrics, Division of Hematology-Oncology, University California San Francisco, San Francisco, CA
²Department of Hematology and Oncology, Klinikum rechts der Isar, Technische Universität München, München, CA, Germany
³Department of Pediatrics, Division of Hematology-Oncology, Benioff Children's Hospital, University of California, San Francisco, San Francisco, CA
⁴Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia, PA
⁵Department of Pediatric Hematology-Oncology, University of Alberta/Stollery Children's Hospital, Edmonton, AB, Canada
⁶Center for Cancer and Blood Disorders, Pediatric Specialists of Virginia, Fairfax, VA
⁷Pediatric Hematology/Oncology & Bone Marrow Transplantation, Oregon Health & Science University, Knight Cancer Institute Doernbecher Children's Hospital, Portland, OR
⁸Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA
⁹Department of Pediatrics, Division of Pediatric Hematology/Oncology, University of California Benioff Children’s Hospital, Seattle, WA
¹⁰Department of Pediatrics, Division of Hematology-Oncology, UCSF, San Francisco, CA

Sudipto Mukherjee, MD, PhD, MPH¹, Doug Cattie, PhD^2*, Naveen Pemmaraju, MD³, Teresa Green^2* and Dan Shaheen, PharmD^2*

¹Department of Hematology and Medical Oncology, Taussig Cancer institute, Leukemia Program, Cleveland Clinic, Cleveland, OH
²Blueprint Medicines, Cambridge, MA
³Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX

Min Jung Kim, MD^*, Min-Young Lee, MD^*, Kyoung Ha Kim, MD, PhD^*, Namsu Lee, MD, PhD^*, Jong Ho Won, MD, PhD and Seug Yun Yoon^*

Division of Hematology & Medical Oncology, Department of Internal Medicine, Soonchunhyang university hospital Seoul, Seoul, Korea, Republic of (South)

Nicola Polverelli, MD, PhD^1*, Michele Malagola, MD¹, Marta Comini^2*, Simona Bernardi, PhD^1,3*, Mariella D'adda^4*, Cinzia Sissa^5*, Francesco Frattini^5*, Mirko Farina, MD^1*, Alessandra Beghin^2*, Enrico Damiani, MD^6*, Luigi Grazioli, MD^7*, Eugenia Accorsi Buttini^1*, Federica Colnaghi, MD^1*, Tatiana Zollner, MD^1*, Davide Bonometti, MD^1*, Simone Maifredi^1*, Enrico Morello, MD^1*, Vera Radici, MD^1*, Alessandro Leoni^1*, Katia Bosio^1,3*, Federica Re^1,3*, Alessandra Tucci, MD^4*, Arnalda Lanfranchi^2* and Domenico Russo, MD⁸

¹Unit of Blood Diseases and Stem Cell Transplantation, ASST Spedali Civili, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy
²Stem Cell Laboratory, Section of Hematology and Blood Coagulation, Clinical Chemistry Laboratory, ASST Spedali Civili di Brescia, Brescia, Italy
³Laboratorio CREA (Centro di Ricerca Emato-oncologica AIL), ASST Spedali Civili of Brescia, Brescia, Italy
⁴Unit of Hematology, ASST Spedali Civili di Brescia, Brescia, Italy
⁵Department of Hematology and Transfusion Medicine, ASST Mantova "Carlo Poma", Mantova, Italy, Mantova, Italy
⁶Unit of General Surgery, ASST Spedali Civili di Brescia, Brescia, Italy
⁷Unit of Radiology, ASST Spedali Civili di Brescia, Brescia, Italy
⁸Unit of Blood Diseases and Stem Cell Transplantation, University of Brescia, ASST Spedali Civili, Brescia, Italy

Animesh Pardanani, MBBS, PhD ¹, Ayalew Tefferi, MD², Amritpal Singh^3*, Aref Al-Kali, MD², Mrinal M. Patnaik, MBBS², William J. Hogan, MB, BCh², Kebede Begna, MD⁴, Michelle A Elliott, MD², Nandita Khera, MD, MPH⁵, Jeanne M. Palmer, MD⁵, Naseema Gangat, MBBS², Attilio Orazi, MD^6*, Katalin Kelemen, MD, PhD^7*, Kaaren K. Reichard, MD^8* and Dong Chen, M.D., Ph.D⁹

¹Mayo Clinic of Rochester, Rochester, MN
²Division of Hematology, Mayo Clinic, Rochester, MN
³Adesh University, Bathinda, India
⁴Divison of Hematology, Mayo Clinic, Rochester, MN
⁵Division of Hematology/Oncology, Mayo Clinic, Phoenix, AZ
⁶Department of Pathology, Texas Tech University Health Science Center El Paso, El Paso, TX
⁷Mayo Clinic Arizona, Scottsdale, AZ
⁸Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
⁹Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN

Frank Stegelmann, MD¹, Lino L. Teichmann, MD^2*, Florian H. Heidel, MD³, Carl C. Crodel, MD^4*, Thomas Ernst, MD⁴, Sebastian Kreil^5*, Andreas Reiter, MD⁵, Sara Otten^1*, Stefanie Schauer^1*, Ruth-Miriam Körber^2*, Kim Kricheldorf^6*, Susanne Isfort^6*, Hartmut Döhner, MD¹, Tim H. Brümmendorf, MD⁶, Martin Griesshammer^7*, Konstanze Döhner, MD¹ and Steffen Koschmieder⁶

¹Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany
²Department of Medicine III, University Hospital Bonn, Bonn, Germany
³Innere Medicin C, Universitätsmedizin Greifswald, Greifswald, Germany
⁴Innere Medizin 2, Hämatologie und Onkologie, Universitätsklinikum Jena, Jena, Germany
⁵Department of Hematology and Oncology, University Hospital Mannheim, Mannheim, Germany
⁶Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany
⁷University Clinic for Hematology, Oncology, Haemostaseology and Palliative Care, Johannes Wesling Medical Center, Minden, University of Bochum, Minden, Germany

Daniel J. DeAngelo, MD, PhD^1*, Andreas Reiter, MD², Tracy I. George, MD³, Deepti H. Radia, MRCPI, FRCPath^4*, Marissa Devlin, BS^5*, Saša Dimitrijević, PhD^6*, Mikael Rinne, PhD^5*, Robyn Scherber, MD, MPH⁵ and Jason Gotlib, MD, MS^7*

¹Dana-Farber Cancer Institute, Boston, MA
²Department of Hematology and Oncology, University Hospital Mannheim, Mannheim, Germany
³ARUP Laboratories, Salt Lake City, UT
⁴Guy's & St Thomas' NHS Foundation Trust, London, United Kingdom
⁵Blueprint Medicines Corporation, Cambridge, MA
⁶Blueprint Medicines (Switzerland) GmbH, Zug, Switzerland
⁷Stanford Cancer Institute/Stanford University School of Medicine, Stanford, CA

Safa Ansar, MSc^1*, Janet Malcolmson, MSc, CGC^2,3*, Kirsten M Farncombe, PhD^4*, Karen Yee, MD¹, Raymond H Kim, MD, PhD^1,5,6,7* and Hassan Sibai, MBBS, MD^1*

¹Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
²Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
³Bhalwani Familial Cancer Clinic, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
⁴Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada
⁵Division of Clinical and Metabolic Genetics, The Hospital for Sick Children, Toronto, ON, Canada
⁶Department of Medicine, University of Toronto, Toronto, ON, Canada
⁷The Ontario Institute for Cancer Research, Toronto, ON, Canada