Shivam Rai^1*, Jan Stetka^2*, MARC Usart^3*, Hui Hao-Shen^2*, Young Park, MS^4*, Remie Houston^4*, Anthony R. Martinez Benitez, BA^4*, Matthew Wereski^4*, Emily Guzzardi, BA^4*, Sonali Persaud, BS^4*, Hailey Ramzan, HS^4*, Alan Futran, PhD^5*, Charley Xu^5*, Jeremy Greenwood^5*, Sayan Mondal, PhD^6*, Craig Masse, PhD^7*, Ross L. Levine, MD⁸, Radek C. Skoda² and Andrew Dunbar, MD⁸

¹Department of Biomedicine, Experimental Hematology, University Hospital Basel and University of Basel, Basel, Basel-Stadt, Switzerland
²Department of Biomedicine, Experimental Hematology, University Hospital Basel and University of Basel, Basel, Switzerland
³Department of Biomedicine, Experimental Hematology, University Hospital Basel and University of Basel, BASEL, Switzerland
⁴Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY
⁵Schrodinger Inc., New York, NY
⁶Schrodinger, Inc., New York
⁷Ajax Therapeutics, Cambridge, MA
⁸Department of Medicine and Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY

Tim Kong, MS¹, Angelo BA Laranjeira, PhD^2*, LaYow Yu^2*, Jared S. Fowles, PhD¹, Fan He, PhD², Maggie J. Allen, BS^2* and Stephen T Oh, MD, PhD¹

¹Division of Hematology, Washington University School of Medicine, St. Louis, MO
²Division of Hematology, Washington University School of Medicine in St. Louis, Saint Louis, MO

Yutaro Suzuki^1*, Yaeko Nakajima-Takagi, PhD^1*, Shuhei Kurosawa, MD, PhD^1*, Ola Rizq, MD, PhD^1*, Ayana Kon, MD, PhD^2*, Etsuro Ito, MD, PhD³, Seishi Ogawa, MD, PhD⁴ and Atsushi Iwama, MD, PhD¹

¹Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan
²Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
³Department of Community Medicine, Hirosaki University Graduate School of Medicine, Aomori, Japan
⁴Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto City, Japan

Jessica E. Pritchard^1,2*, Juliette Pearce, PhD^1*, Inge Snoeren^2,3*, Stijn Fuchs^2,3*, Katrin Götz, MSc^1*, Silke Wagner^1*, Kathrin Olschok, MSc^4,5*, Nicolas Chatain, PhD^4,5*, Steffen Koschmieder^5,6, Marie-Luise Berres, MD, PhD^5,7*, Ivan Costa, PhD^8*, Helene Gleitz, PhD^2,9*, Rafael Kramann, MD, PhD^10,11,12* and Rebekka K. Schneider, MD, PhD^3,13,14

¹Institute for Cell and Tumor Biology, RWTH Aachen University Hospital, Aachen, Germany
²Department of Developmental Biology, Erasmus University Medical Center, Rotterdam, Netherlands
³Department of Developmental Biology, Erasmus MC, Rotterdam, Netherlands
⁴Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany
⁵Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), Aachen, Germany
⁶Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Faculty of Medicine, University Hospital of Aachen, Aachen, Germany
⁷Medical Department III, RWTH University Hospital Aachen, Aachen, Germany
⁸Institute for Computational Genomics, RWTH Aachen University, Aachen, Germany
⁹Oncode Institute, Erasmus University Medical Center Cancer Institute, Rotterdam, Netherlands
¹⁰Department of Internal Medicine, Nephrology and Transplantation, Erasmus University Medical Center, Rotterdam, Netherlands
¹¹Institute of Experimental Medicine and Systems Biology, RWTH Aachen University Hospital, Aachen, Germany
¹²Department of Nephrology and Clinical Immunology, RWTH Aachen University Hospital, Aachen, Germany
¹³Institute for Cell and Tumor Biology, RWTH Aachen University Hospital, Lemiers, Netherlands
¹⁴Oncode Institute, Erasmus MC, Rotterdam, Netherlands

Sonia Aguila, PhD^1,2*, Ernesto J Cuenca^1,3,4*, Maria Jose Lys, MD^5*, Carmen Garcia-Hernandez, MD^6*, Maria Jose Fernández^7*, Maria Noya^8*, Valentín García Gutiérrez, PhD⁹, Luis Palomera, MD, PhD^10*, Alicia Senín, MD^11*, Raul Perez Lopez, MD, PhD^12*, Manuel Pérez-Encinas, MD^13*, Anna Angona, MD^14*, Jose M Puerta^15*, Rolando Vallansot, MD^16*, Venancio Conesa^17*, Juan Carlos Hernandez Boluda, MD, PhD^18*, Ana Rosell^19*, Montse Cortes, MD^20*, Guillermo Ortí, MD, PhD^21*, Blanca Xicoy, MD^22*, Gonzalo Carreño, MD PhD^23*, Elvira Mora Castera, MD^24*, Pilar Giraldo, PhD²⁵, Maria Luisa Lozano, MD, PhD^1,3,4*, Luis Felipe Casado, MD^26*, Francisca Ferrer Marin, MD, PhD^1,2,3 and on Behalf Of Gelmc^27*

¹Servicio de Hematología y Oncología Médica. H.U. Morales Meseguer. Centro Regional de Hemodonación. IMIB-Arrixaca, Murcia, Spain
²UCAM, Murcia, Spain
³CIBERER U-765, Murcia, Spain
⁴Universidad de Murcia, Murcia, Spain
⁵Consorcio HGU de Valencia, Valencia, Spain
⁶Hospital General de Alicante, Alicante, Spain
⁷Hospital Dr Peset, Valencia, Spain
⁸H Teresa Herrera, CHUAC, A Coruña, Spain
⁹HU Ramón y Cajal. IRYCIS, Madrid, Spain
¹⁰Hospital Clínico U. "Lozano Blesa". Instituto Investigación Sanitaria Aragón, Zaragoza, Spain
¹¹H Duran i Reynals. Institut Català d' Oncologia, Barcelona, Spain
¹²HU Virgen de la Arrixaca, Murcia, Spain
¹³H Clínico U. Santiago de Compostela, A Coruña, Spain
¹⁴HU Dr. J Trueta - Institut Català d'Oncologia, Girona, Spain
¹⁵H Virgen de las Nieves, Granada, Spain
¹⁶H Joan XXIII. Institut Català d' Oncologia, Tarragona, Spain
¹⁷HGU de Elche, Alicante, Spain
¹⁸H Clínico U. de Valencia, Valencia, Spain
¹⁹HU Virgen de la Victoria, Málaga, Spain
²⁰HG de Granollers, Barcelona, Spain
²¹HU Vall d’Hebron, Barcelona, Spain
²²HU German Trias i Pujol - Institut Català d' Oncologia, Barcelona, Spain
²³Hospital Universitario 12 de Octubre, Madrid, Spain
²⁴H Universitario y Politécnico La Fe, Valencia, Spain
²⁵Quirón Salud, Zaragoza, Spain
²⁶H Virgen de la Salud, Toledo, Spain
²⁷GELMC, Madrid, Spain

Billy Truong¹, Yong Zhang, MD, PhD¹, Esteban Martinez, BSc^1*, Brianna Trankle, BS^2*, Anna-Mariya Kukuyan, PhD^3*, Susan Shinton, BS^1*, James Oesterling^4*, Xiang Hua, MS^5*, Dietmar J Kappes, PhD^1*, Joan Font-Burgada, PhD^2*, Tomasz Skorski, MD, PhD⁶ and David Wiest, PhD¹

¹Blood Cell Development and Function Program, Fox Chase Cancer Center, Philadelphia, PA
²Cancer Signaling and Epigenetics, Fox Chase Cancer Center, Philadelphia, PA
³Fels Cancer institute For Personalized Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA
⁴Cell Sorting Facility, Fox Chase Cancer Center, Philadelphia, PA
⁵Transgenic Mouse Facility, Fox Chase Cancer Center, Philadelphia, PA
⁶Fels Cancer Institute for Personalized Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA

Emilio Ramos, MD, PhD¹ and Arun Wiita, MD, PhD^2*

¹Department of Laboratory Medicine, University of California San Francisco, SF, CA
²UCSF, SF, CA

Xiaomeng Huang, PhD^1*, Jonathan M. Ahmann, BS^2*, Opal S. Chen, PhD^2*, Yi Qiao, PhD^1*, Anthony D. Pomicter, MS^3*, Gabor T. Marth, DSc^1*, Tracy I. George, MD⁴ and Michael W. Deininger, MD, PhD⁵

¹Eccles Institute of Human Genetics, University of Utah, Salt Lake City, UT
²Huntsman Cancer Institute, University of Utah, Salt Lake City, UT
³Division of Hematology and Hematologic Malignancies, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT
⁴University of Utah and ARUP Laboratories, Salt Lake City, UT
⁵Versiti Blood Research Institute, Milwaukee, WI

Aram Bidikian^1*, Sreyashi Basu, PhD^2*, He Zhong^3*, Himachandana Atluri, MD⁴, Jabra Zarka, MD^5*, Michael Andreeff, MD, PhD¹, Koji Sasaki, MD¹, Elias Jabbour, MD¹, Jorge E. Cortes, MD⁶, Padmanee Sharma, MD, PhD^7* and Ghayas C. Issa, MD¹

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Immunology, UT M. D. Anderson Cancer Center, Houston, TX
³The University of Texas MD Anderson Cancer Center, Houston, TX
⁴Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
⁵Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA
⁶Georgia Cancer Center, Augusta, GA
⁷Department of Immunology, The University of Texas M.D. Anderson Cancer Center, Houston, TX

Soo Jin Kim, MS^1*, Jihyun Song, PhD¹, Nicolas Papadopoulos^2*, Jessica Meznarich, MD³, Grace Min^1,4*, Stefan N. Constantinescu, MD, PhD² and Josef T. Prchal, MD¹

¹Division of Hematology, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT
²Ludwig Institute for Cancer Research, Brussels, Belgium
³Division of Hematology-Oncology, Department of Pediatrics, University of Utah, Salt Lake Cty, UT
⁴Skyline High School, Salt Lake City

Tyler M. Parsons, PhD^1*, Aishwarya Krishnan, MS^2*, Wentao Han^3*, Andrew L Young, MD, PhD⁴ and Grant A Challen, PhD¹

¹Division of Oncology, Washington University School of Medicine, St. Louis, MO
²Division of Biology and Biomedical Sciences, Washington University School of Medicine, St. Louis, MO
³Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, MO
⁴Department of Medicine, Division of Oncology, Washington University School of Medicine In St. Louis, Saint Louis, MO

Daniel C Choi, MD, Ghaith Abu-Zeinah, MD, Silvana Di Giandomenico, PhD, Katie Erdos^* and Joseph Scandura, MD, PhD

Richard T. Silver, M.D. Myeloproliferative Neoplasms (MPN) Center, Weill Cornell Medicine, New York, NY

John Mascarenhas, MD¹, Oleh Zagrijtschuk, MD^2*, Craig Zimmerman, PhD^3*, Albert Qin, MD, PhD^4* and Raymond W Urbanski, MD, PhD⁵

¹Department of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY
²MyeloPro Diagnostics and Research GmbH, Vienna, Austria
³PharmaEssentia, Taipei, Taiwan
⁴PharmaEssentia U.S.A. Corp., Burlington, MA
⁵PharmaEssentia, CALABASAS, CA

Jessica Burroughs Garcia^1*, Paola Storti, PhD^2*, Nicolas Thomas Iannozzi, MS^2*, Laura Notarfranchi^2*, Denise Toscani, PhD^2*, Valentina Marchica, MS^2*, Vincenzo Raimondi, MS^2*, Luca Agnelli^3*, Valentina Franceschi, PhD^4*, Giannalisa Todaro, PhD^5*, Oxana Lungu, MS^2*, Matia Bernardi, MD^5*, Matteo Scita, MD^5*, Gabriella Sammarelli, PhD^5*, Gaetano Donofrio, DVM PhD^4*, Anna Benedetta Dalla Palma, MD PhD^5* and Nicola Giuliani, MD, PhD^2,5

¹Hematology and BMT Unit, University of Parma, Parma, Italy
²Department of Medicine and Surgery, University of Parma, Parma, Italy
³Department of Pathology and Department of Molecular Oncology 1, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy
⁴Department of Medical-Veterinary Science, University of Parma, Parma, Italy
⁵Hematology and BMT Unit, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy

Graeme M Greenfield, BA, BMBCh, MRCP, FRCPath^1*, Deirdra Venney, BSc^2*, Jaine Blayney, PhD^3*, Mary Frances McMullin, MD, FRCPath, FRCP⁴ and Ken I Mills, BSc, PhD, FRCPath¹

¹Patrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, United Kingdom
²Queen's University Belfast, Belfast, NI, United Kingdom
³Queen's University Belfast, Belfast, United Kingdom
⁴Centre for Medical Education, Queen's University, Belfast, United Kingdom

Luo Dongmei^1*, Na Xu, MD, PhD^2*, Xiaoli Liu^2*, Jie Luo^3*, Hanyin Liang^4*, Zherou He, MBBS^5*, Hong Chen^1*, Qiang Wang^2,6* and Xuan Zhou, PhD^7*

¹southern hospital, Guangzhou, China
²Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China
³Department of Hematology, Nanfang Hospital,Southern Medical University, Guangzhou, China
⁴Department of Hematology, Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China
⁵Southern Medical University Nanfang Hospital, Guangzhou, AL, China
⁶Huntsman Cancer Institute, The University of Utah, SALT LAKE CITY, UT
⁷Department of Hematology,Nanfang Hospital,Southern Medical University, Guangzhou, China