Katia Beider^1*, Noy Sharvit Boaron^1*, Valeria Voevoda^1*, Olga Ostrovsky, PhD^1*, Ivetta Danylesko, MD^1*, Avichai Shimoni, MD^2*, Amnon Peled, PhD^3* and Arnon Nagler, MD¹

¹Division of Hematology and Bone Marrow Transplantation, Chaim Sheba Medical Center, Ramat-Gan, Israel
²Division of Hematology and Bone Marrow Transplantation, Chaim Sheba Medical Center, Ramat Gan, Israel
³Hadassah Hebrew University Medical Center, Goldyne Savad Institute of Gene Therapy, Jerusalem, Israel

Yuto Takahashi, BSc^1*, Akihiro Kitadate, MD, PhD², Sho Ikeda, MD, PhD^2*, Sayaka Iwama^1*, Ko Abe^2*, Hiroyuki Tagawa, MD, PhD², Hideki Wakui, MD, PhD^1* and Naoto Takahashi, MD, PhD²

¹Department of Life Science, Akita University Graduate School of Engineering Science, Akita, Japan
²Department of Hematology, Nephrology, and Rheumatology, Akita University Graduate School of Medicine, Akita, Japan

Anya Levinson, MD¹, Karensa Tjoa^2*, Benjamin J. Huang, MD^3*, Lauren K. Meyer, MD, PhD⁴, Samuel W Brady, PhD^5*, Jinghui Zhang, PhD^6*, Kevin M. Shannon, MD⁷ and Anica Wandler, PhD^7*

¹University of California, San Francisco, University, San Francisco, CA
²UCSF, San Francisco, CA
³Dept. of Pediatrics, Division of Hematology/Oncology, University of California San Francisco, San Francisco, CA
⁴University of Washington, Seattle, WA
⁵St. Jude Children's Research Hospital, Memphis, TN
⁶Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN
⁷Department of Pediatrics, University of California, San Francisco, San Francisco, CA

Ruifeng Sun, BS^1*, Jaewoong Lee, PhD^1*, Tim Wartewig, MD, PhD¹, Mark E. Robinson, PhD^1*, Alberto Bigogno^1*, David Fonseca Arce^1*, Abu-Sayeef Mirza, MD, MPH², Andrew Takeda^1*, Lars Klemm^1*, Vivasvan Vykunta^3*, Brian Shy^3*, Alexander Marson, MD PhD^3* and Markus Müschen, MD¹

¹Center of Molecular and Cellular Oncology and Department of Immunobiology, Yale University, New Haven, CT
²Yale University, School of Medicine, Hematology, New Haven, CT
³Department of Medicine, University of California, San Francisco, San Francisco, CA

Ryan T Bishop, PhD¹, Tao Li, MD^1*, Raghunandan Reddy Alugubelli, MS^2,3*, Mark Meads, PhD^4*, Bin Fang^5*, Gabriel De Avila, BS^6*, Oliver Hampton, PhD^7*, Steven Grant, MD⁸, John M. Koomen^5*, Ariosto Siqueira Silva, PhD^9,10*, Kenneth H. Shain, MD, PhD¹¹ and Conor Lynch, PhD¹²

¹Department of Tumor Biology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
²Collaborative Data Services Core, Moffitt Cancer Center, Tampa, FL
³Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
⁴Hematologic Malignancies, H Lee Moffitt Cancer Center, Tampa, FL
⁵Moffitt Cancer Center, Tampa, FL
⁶Department of Blood and Marrow Transplant and Cellular Immunotherapy, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL
⁷M2GEN, Tampa, FL
⁸VCU Massey Cancer Center, Richmond, VA
⁹Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL
¹⁰Department of Malignant Hematology, Moffitt Cancer Center, Tampa
¹¹Department of Malignant Hematology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL
¹²Department of Tumor Biology, Moffitt Cancer Center, Tampa, FL

Hiroshi Imanaga^1*, Yuichiro Semba, MD^1*, Kensuke Sasaki, MD, PhD^1*, Kiyoko Miyata, PhD^2*, Takuji Yamauchi, MD, PhD^1*, Tatsuya Terasaki, MD^1*, Fumihiko Nakao, MD^1*, Shigeki Hirabayashi, MD, PhD^2*, Jumpei Nogami, PhD^1*, Koichi Akashi, MD, PhD¹ and Takahiro Maeda, MD, PhD²

¹Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
²Division of Precision Medicine, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan

Warren C. Fiskus, BSc, PhD¹, Kaberi Das^2*, Christopher Peter Mill, PhD, BA³, Christine E Birdwell, PhD^4*, John A. Davis^4*, Noor Alhamadani^4*, Kevin Philip^4*, May Tan, BSc^5*, Robert A Brown, MD⁶, Michael R. Green, PhD⁷ and Kapil N. Bhalla, MD⁸

¹Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX
²UT MD Anderson Cancer Center, Houston, TX
³MD Anderson Cancer Center, Houston, TX
⁴The University of Texas MD Anderson Cancer Center, Houston, TX
⁵Nurix Therapeutics, Inc., San Francisco, CA
⁶Nurix Therapeutics, San Francisco, CA
⁷Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Friendswood, TX
⁸Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX

Yang Han, MD^1,2*, Ya Zhang, MD^1,2*, Xinting Hu^1,3, Hua Wang, MM^1,2*, Xin Zhang, MM^1,2*, Zheng Tian, MM^2* and Xin Wang, MD, PhD^1,2

¹Department of Hematology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China
²Department of Hematology, Shandong Provincial Hospital, Shandong University, Jinan, Shandong, China
³Department of Hematology, Shandong Provincial Hospital, Shandong University, Jinan, China

Min Sui^1*, Chunhua Song, MD，PhD^2,3 and Zheng Ge, MD, PhD¹

¹Department of Hematology, Zhongda Hospital, School of Medicine, Institute of Hematology, Southeast University, Nanjing, China
²Hershey Medical Center, Pennsylvania State University Medical College, Hershey
³Division of Hematology, The Ohio State University Wexner Medical Center, the James Cancer Hospital, Columbus

Mohd Minhajuddin, PhD¹, Amanda C. Winters, MD, PhD², Marc Schwartz, MD³, Daniel A. Pollyea, MD⁴ and Craig T Jordan, PhD⁵

¹Division of Hematology, University of Colorado, Anschutz Medical Campus, RC2; 10th floor; Room# 10440D, CO
²University of Colorado Anschutz Medical Campus, Aurora, CO
³University of Colorado, Denver, CO
⁴Anschutz Medical Campus, Division of Hematology, University of Colorado School of Medicine, Denver, CO
⁵University of Colorado, Aurora, CO

Karen Sweiss, PharmD¹, Pritesh Patel², Janet Guo^3*, Kyeongmin Kim^3*, Kasey Hill^3*, Nicole Abbott^3*, Jeremy Johnson, PharmD, PhD^4*, Donald Irby, PhD^3*, John G. Quigley, MD, FRCP (C)², Damiano Rondelli, MD², R Donald Harvey, PharmD⁵, Ajay K. Nooka, MD, MPH, FACP⁶, Madhav Dhodapkar, MBBS⁷, Jonathan L. Kaufman, MD⁵, Nisha S. Joseph, MD⁸, Sagar Lonial, MD⁵, Douglas W. Sborov, MD⁹, Mitch A Phelps^3* and Craig C Hofmeister, MD⁵

¹Department of Pharmacy Practice, University of Illinois at Chicago, Hinsdale, IL
²Division of Hematology and Oncology, University of Illinois at Chicago, Chicago, IL
³Division of Pharmaceutics and Pharmacology, College of Pharmacy, Comprehensive Cancer Center, The Ohio State University, Columbus, OH
⁴Department of Pharmacy Practice, University of Illinois at Chicago, Chicago, IL
⁵Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA
⁶Winship Cancer Institute of Emory University, Atlanta, GA
⁷Emory University, Atlanta, GA
⁸Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Louisville, KY
⁹Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT

Peipei Yang^1*, Ying Qu, PhD^1*, Mengyao Wang^1*, Bingyang Chu^2*, Wen Chen^2*, Yuhuan Zheng, PhD^1*, Zhiyong Qian, PhD^2* and Ting Niu¹

¹Department of Hematology, West China Hospital, Sichuan University, Chengdu, China
²State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China

Meiying Yang^1*, Jonathan Scott Rink, PhD^1*, Shuo Yang, PhD^1*, Eva Yang, BS^1*, Kaylin Marie McMahon, PhD^2*, Colby Shad Thaxton, MD, PhD^3,4*, Leo I. Gordon, MD¹ and Adam Yuh Lin, MD, PhD¹

¹Department of Medicine, Division of Hematology/Oncology and the Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Northwestern University Feinberg School of Medicine, Chicago, IL
²Zylem Biosciences, Chicago
³International Institute for Nanotechnology, Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL
⁴Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL

Samantha Hurwitz¹, Heather Ogana¹, Zesheng Wan, PhD^1*, Fariba Navid, MD^2*, Deepa Bhojwani, MD³, Kimberly Holloway, PhD^4*, Michael Lieber^5*, Chih-Lin Hsieh^6* and Yong-Mi Kim, MD, PhD, MPH¹

¹Division of Hematology and Oncology, Department of Pediatrics, Children's Hospital of Los Angeles, University of Southern California, Los Angeles, CA
²Division of Hematology and Oncology, Department of Pediatrics, Children's Hospital Los Angeles, University of Southern California, Los Angeles
³Children's Hospital of Los Angeles, Los Angeles, CA
⁴Iterion Therapeutics, Houston, TX
⁵Pathology, USC Norris Cancer Ctr., Los Angeles, CA
⁶Urology, USC Norris Cancer Ctr., Los Angeles, CA

Diana Malarikova, MD^1,2*, Radek Jorda, PhD^3*, Alexandra Dolníková, MSc^4*, Ondrej Havranek, MD, PhD^1,5, Eva Pokorna^4*, Dmitry Kazantsev, PhD^4*, Dana Sovilj^6*, Karel Helman^7*, Magdalena Klanova, MD, PhD^1,4*, Ladislav Andera, MSc, PhD^6*, Miroslav Strnad, Prof.^8*, David Chiron, PhD^9*, Marek Trneny, MD¹ and Pavel Klener Jr., Prof., MD, PhD^1,4*

¹First Department of Internal Medicine - Hematology, General University Hospital and First Faculty of Medicine, Charles University, Prague, Czech Republic
²Institute of Pathological Physiology, First Faculty of Medicine, Charles University, Prague, AL, Czech Republic
³Department of Experimental Biology, Faculty of Science, Palacky University, Olomouc, Czech Republic
⁴Institute of Pathological Physiology, First Faculty of Medicine, Charles University, Prague, Czech Republic
⁵BIOCEV, First Faculty of Medicine, Charles University, Vestec, Czech Republic
⁶Institute of Biotechnology, Czech Academy of Sciences, Vestec, Czech Republic
⁷Faculty of Informatics and Statistics, University of Economics, Prague, Czech Republic
⁸Laboratory of Growth Regulators, Palacky University and Institute of Experimental Botany, Olomouc, Czech Republic
⁹CRCI2NA, Integrated Research Center in Immunology and Oncology, Nantes University, Nantes, France

Julie A.S. Lammers, BSc^1*, Hoang Mai Phuong, PhD^1*, Charmaine Ong, BSc^1*, Min Liu, MSc^1*, Patrick Jaynes, PhD^1*, Raji R. Nair, PhD^2*, Wee Joo Chng, MBChB PhD^1,3,4,5, Chandler D. Robinson, MD MBA MSc^2* and Anand D. Jeyasekharan, MBBS MRCP FAMS PhD^1,3,4,5*

¹Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore
²Monopar Therapeutics, Wilmette, IL
³Department of Haematology-Oncology, National University Health System, Singapore, Singapore
⁴Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
⁵NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

Philipp Sergeev, MSc^1*, Sadiksha Adhikari^2*, Juho J. Miettinen, PhD^1*, Maiju-Emilia Huppunen, MSc^1*, Minna Suvela, MSc^1*, Ana Slipicevic, PhD^3*, Nina N. Nupponen, PhD^3*, Klara Acs, PhD^3*, Fredrik Lehmann^3* and Caroline A. Heckman, PhD⁴

¹Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science, iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland
²Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science, iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science, iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland
³Oncopeptides AB, Stockholm, Sweden
⁴Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland

Erica Dander, PhD^1*, Alessandra Fallati, PhD Student^1*, Rita Starace, PhD Student^1*, Alice Giussani, PhD Student^1*, Mario Mauri, PhD^2*, Rocco Piazza, MD, PhD^3*, Carmelo Rizzari^4*, Andrea Biondi, MD¹ and Giovanna D'Amico, BSc, PhD, MSc¹

¹Tettamanti Research Center, Department of Pediatrics, University of Milano - Bicocca/Fondazione MBBM, Monza, Italy
²Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy
³Hematology, Department of Medicine, University of Milano-Bicocca, Monza, Italy
⁴Pediatric Hematology-Oncology Unit, University of Milano-Bicocca, MBBM Foundation, San Gerardo Hospital, Monza, Italy

Anfal Alsadhan, PhD^1,2,3*, Jonathan Chen^1*, Clare Sun, MD¹, Chingiz Underbayev, MD, PhD¹, Elena Bibikova, PhD^4*, Tanja Nicole Hartmann, PhD⁵, Maissa Mhibik, PhD^1* and Adrian Wiestner, MD¹

¹Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
²Catholic University of America, Washington DC
³King Saud bin Abdulaziz University for Health Sciences, Riyadh, MD, Saudi Arabia
⁴AstraZeneca, South San Francisco, CA
⁵Department of Internal Medicine I, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany

Natsumi Kawasaki, PhD^*, Mayu Tomita^*, Yoriko Yamashita-Kashima, PhD^*, Yasushi Yoshimura, MS^* and Shigeki Yoshiura, PhD^*

Product Research Department, Chugai Pharmaceutical Co., Ltd., Kamakura, Japan

Peiqi Zhao^1*, Shiyong Zhou^2*, Lihua Qiu^2*, Lanfang Li^1*, Zhengzi Qian^2*, Kai Fu³ and Huilai Zhang, M.D.^1*

¹Tianjin Medical University Cancer Institute and Hospital, Tianjin, China
²Department of Lymphoma, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’s Clinical Research Center for Cancer, Tianjin, China
³Pathology, Univ. of Nebraska Medical Ctr., Omaha, NE

Keyu Li^*, Rui Yun^*, Min Chai, PhD^*, Poonam Yakkundi, PhD^*, Rodnie Rosete^*, Gene Li, PhD^*, Liqin Liu, PhD^*, Dean Ng, PhD^*, Paul R. Hinton^*, Maya F. Kotturi, PhD^*, Angus M. Sinclair, PhD, Stephen F. Carroll, PhD^*, Umesh Muchhal, PhD^* and Bruce A. Keyt, PhD

IGM Biosciences, Inc., Mountain View, CA

Elisa Fiorito, PhD^1*, Roman Generalov^1*, Stian Foss, PhD^2,3*, Helen Heyerdahl, PhD^1*, Ada Repetto-Llamazares, PhD^1*, Veronique Pascal, PhD, PharmD^1*, Geir E Tjønnfjord, MD^4,5, Sigrid Strand Skånland, PhD^5,6*, Jan Terje Andersen, PhD^2,3* and Jostein Dahle, PhD^1*

¹Research and Development department, Nordic Nanovector ASA, Oslo, Norway
²Department of Immunology, Oslo University Hospital Rikshospitalet, Oslo, Norway
³Institute of Clinical Medicine and Department of Pharmacology, University of Oslo, Oslo, Norway
⁴Department of Haematology, Oslo University Hospital, Oslo, Norway
⁵K.G. Jebsen Centre for B cell malignancies and Institute of Clinical Medicine, University of Oslo, Oslo, Norway;, Oslo, Norway
⁶Department of Cancer Immunology, Institute for Cancer Research, Oslo University Hospital, Montebello, Oslo, Norway, Oslo, Norway

David Chiron, PhD^1*, Emmanuelle Menoret, PhD^2*, Charlotte Kervoelen, PhD^2*, Sophie Maïga^1*, Celine Bellanger^1*, Benoit Tessoulin, MD^1,3*, Cyrille Touzeau^1,3*, Hélène Asnagli, PhD^4*, Andy Parker, PhD^4*, Philip Beer, MD, PhD^4* and Catherine Pellat-Deceunynck, PhD¹

¹CRCI2NA, Integrated Research Center in Immunology and Oncology, Nantes University, Nantes, France
²Therassay (Onco-Hemato) Core Facility, Nantes Université, Capacités, Nantes, France
³Hematology Department, Nantes University Hospital, Nantes, France
⁴Step Pharma, Saint-Genis-Pouilly, France

Tingting Liu^1*, Vi Lam^2*, Elana Thieme, BS^1*, Olga Danilova^1*, Nur Bruss, BS^3*, Lapo Alinari, MD, PhD⁴, Jeffrey W. Tyner⁵, Stephen E. Kurtz, PhD^6*, Zheng Xia^3* and Alexey V Danilov, MD⁷

¹City of Hope, Duarte, CA
²City Of Hope, Duarte, CA
³Oregon Health and Science University, Portland, OR
⁴Department of Internal Medicine, Division of Hematology, College of Medicine, The Ohio State University, Columbus, OH
⁵Oregon Health & Science University, Portland, OR
⁶Knight Cancer Institute, Mail code: KR-HEM, Oregon Health & Science University, Portland, OR
⁷City of Hope, La Canada Flintridge, CA

Manpreet Bariana, PhD^1*, Beilu Zhang^2*, Jingyu Sun^2*, Elena Cassella, M.S.^1*, Janice Rateshwar^1*, Ming Tony Tan, PhD^3*, Weiwei Wang^2*, Jinping Wang^4*, Rena Feinman, PhD⁵, David Samuel Siegel, MD, PhD⁶, Hsiou-Chi Liou, Ph.D.^7*, Samedy Ouk, Ph.D.^8*, Patrizia Mondello, MD, PhD, MSc⁹, Hongjun Wang, PhD^2* and Johannes Zakrzewski, MD¹

¹Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ
²Stevens Institute of Technology, Hoboken
³Department of Biostatistics, Bioinformatics, and Biomathematics, Georgetown University Medical Center/Lombardi Comprehensive Cancer Center, Washington, DC
⁴Stevens institute of Technology, Hoboken
⁵Center for Discovery and Innovation, Hackensack University Medical Center, Nutley, NJ
⁶John Theurer Cancer Center, Division of Multiple Myeloma, Hackensack University Medical Center, Hackensack, NJ
⁷ImmuneTarget Inc., San Diego
⁸ImmuneTarget Inc., San Diego, CA
⁹Division of Hematology, Mayo Clinic, Rochester, MN