Leo Meriranta, MD^1*, Selma Sorri, MS^2*, Sadia Zafar, PhD^2*, Xiaonan Liu, PhD^3*, Eerika Sahlberg, MD^4*, Olli Dufva^5*, Helka Göös, PhD^3*, Marja-Liisa Karjalainen-Lindsberg, MD, PhD^6*, Markku Varjosalo, PhD^3*, Marko Hyytiäinen, PhD^2* and Sirpa Leppa, MD, PhD^1,7

¹Research Programs Unit, Applied Tumor Genomics, Faculty of Medicine, University of Helsinki, Helsinki, Finland
²Research Programs Unit, Applied Tumor Genomics, University of Helsinki, Helsinki, Finland
³Institute of Biotechnology, HiLIFE, Proteomics Unit, University of Helsinki, Helsinki, Finland
⁴Faculty of Medicine, University of Helsinki, Helsinki, Finland
⁵Translational Immunology Research Program, University of Helsinki, Helsinki, Finland
⁶Helsinki University Hospital, Helsinki, Finland
⁷Department of Oncology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland

Joseph R. Krambs, BS¹, Kimberly B. Johansson, BA², Isabelle Genter, BS^3*, Sai Mukund Ramakrishnan, MS^4*, Christopher A Miller, PhD^4* and Daniel C. Link, MD⁵

¹Division of Oncology, Department of Medicine, Washington University School of Medicine, High Ridge, MO
²Medical Scientist Training Program, Washington University in St. Louis, Saint Louis, MO
³Washington University in St. Louis, Saint Louis, MO
⁴Department of Medicine/Division of Oncology, Washington University School of Medicine, Saint Louis, MO
⁵Department of Medicine/Division of Oncology, Washington University School of Medicine, St. Louis, MO

Guillaume P Andrieu, PhD^1,2*, Mathieu Simonin, MD^3*, Aurélie Cabannes-Hamy, MD^4*, Etienne Lengline, MD^5*, Ambroise Marçais, MD, PhD^6*, Marie Emilie Dourthe, MD^7,8,9*, Nicolas Boissel, MD, PhD¹⁰, Hervé Dombret, MD, PhD¹¹, Philippe Rousselot, MD, PhD^12*, Olivier Hermine, MD, PhD¹³ and Vahid Asnafi, MD, PhD^3,14*

¹Laboratoire d'Onco-Hématologie, Hôpital Necker-Enfants Malades, Assistance Publique-Hopitaux De Paris, Paris, France
²Assistance Publique-Hopitaux De Paris (AP-HP), Hopital Necker Enfants-Malades, Paris, France
³Institut Necker-Enfants Malades, INSERM U1151, Paris, France
⁴Hemato-Oncology Department, Andre Mignot Hospital, Le Chesnay, FRA
⁵Hematology Department, Saint-Louis Hospital AP-HP Paris France, Paris, France
⁶Hematology Department, Necker University Hospital, PARIS, France
⁷Laboratory of onco-hematology, UMR 1151, Institut Necker Enfants Malades, Université Paris Descartes Sorbonne cité, Paris, France
⁸Pediatric Hematology-Immunology Department, Hôpital Necker Enfants Malades, Paris, France
⁹Pediatric Hematology-Immunology Department, Robert Debré Hospital, APHP, Paris, France
¹⁰Hematology Adolescent and Young Adult Unit, France, Paris Cedex 10, France
¹¹Division of Hematology, EA3518 Saint-Louis Institute for Research, Hôpital Saint-Louis, APHP, University of Paris, Paris, France, Paris, France
¹²Hematology Department, Centre Hospitalier de Versailles, LE CHESNAY CEDEX, France
¹³Department of Hematology, Necker Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France
¹⁴Laboratoire d'Onco-Hématologie, Hôpital Necker-Enfants Malades, Assistance Publique Hôpitaux de Paris (APHP), Paris, France

Hyoju Kim^1*, Tze King Tan, PhD^1*, Xiao Zi Huang^1*, Jolynn Ong, PhD^1*, Rui Yokomori, PhD^1*, Allen Eng Juh Yeoh, MD^2,3, Takaomi Sanda, MD, PhD^1,4 and Shi Hao Tan, PhD^1*

¹Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore
²National University Children’s Medical Institute, National University Health System, Singapore, Singapore
³Division of Haematology-Oncology, Department of Paediatrics, National University Hospital Singapore, Singapore, Singapore
⁴Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

Feng Yan, PhD^1*, Cedric Tremblay, PhD^1*, Francine Garret-Bakelman, M.D, Ph.D^2*, Jesslyn Saw, BSc^1*, Matthew P. McCormack, PhD^3*, Shokoufeh Abdollahi, MS^1*, Pieter Van Vlierberghe, PhD⁴, David Powell, PhD^5*, Nicholas C. Wong, BSc (Hons) PhD^5* and David J. Curtis, MBBS, PhD⁶

¹Australian Centre for Blood Diseases, Monash University, Melbourne, Australia
²Department of Medicine and Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA
³iCamuno Biotherapeutics, Melbourne, Australia
⁴Cancer Research Institute Ghent (CRIG), Ghent, Flanders, Belgium
⁵Monash Bioinformatics Platform, Monash University, Melbourne, Australia
⁶Australian Centre for Blood Diseases, Monash University, Melbourne, VIC, Australia

Kohei Kume, PhD^1*, Zhengshan Chen, MD-PhD^2*, Lai N. Chan, PhD³, Mark E. Robinson, PhD^3*, Etienne Leveille, MD³, Jaewoong Lee, PhD^3*, Kadriye Nehir Cosgun, PhD^3*, David Fonseca Arce^3*, Dhruv Khanduja^3*, Lars Klemm^3* and Markus Müschen, MD³

¹Center of Molecular and Cellular Oncology and Department of Immunobiology, Yale University, Duarte, CA
²Department of Pharmacology, Kaiser Permanente Riverside Medical Center, Riverside, CA
³Center of Molecular and Cellular Oncology and Department of Immunobiology, Yale University, New Haven, CT

Zunsong Hu, PhD^1,2, Zhilian Jia, PhD^3,4, Behzad Damirchi^1,4* and Zhaohui Gu, PhD^1,4

¹Department of Computational and Quantitative Medicine, Beckman Research Institute of City of Hope, Duarte, CA
²Department of Systems Biology, Beckman Research Institute of City of Hope, Baldwin Park, CA
³Department of Computational and Quantitative Medicine, Beckman Research Institute of City of Hope, Arcadia, CA
⁴Department of Systems Biology, Beckman Research Institute of City of Hope, Duarte, CA

Sabrina A Smith, BSc^1,2*, Laura Garcia Prat, PhD, BSc, MSc², Mohsen Hosseini^2*, Liqing Jin^2*, Nathan Mbong^2*, Monica Doedens^2*, Jessica McLeod, BSc^2*, Julie A. Reisz^3*, Rebecca Wilkerson^3*, Angelo D'Alessandro, PhD³, Steven M. Chan, MD, PhD⁴, Courtney L Jones, PhD² and John E. Dick, PhD^1,5

¹Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
²Princess Margaret Cancer Centre; University Health Network, Toronto, ON, Canada
³Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, CO
⁴Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
⁵Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada

Kelly R. Barnett, PhD^1,2*, Jonathan D. Diedrich, PhD^1,2*, Brennan P. Bergeron, MS^1,2,3*, Wenjian Yang, PhD^1,2*, Kristine R. Crews, PharmD^1,2*, Wendy Stock, MD⁴, Elisabeth Paietta, PhD^5*, Steven M. Kornblau, MD⁶, Hiroto Inaba, MD, PhD^1,7, Sima Jeha, MD^1,7, Ching-Hon Pui, MD^1,7, Mary V. Relling, PharmD^1,2, William E. Evans, PharmD^1,2, Jun J. J. Yang, PhD^1,8,9 and Daniel Savic, PhD^1,2,3,8

¹Hematological Malignancies Program and Center for Precision Medicine in Leukemia, St. Jude Children's Research Hospital, Memphis, TN
²Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN
³Graduate School of Biomedical Sciences, St. Jude Children's Research Hospital, Memphis, TN
⁴Comprehensive Cancer Center, University of Chicago Medicine, Chicago, IL
⁵Albert Einstein College of Medicine, New York, NY
⁶Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
⁷Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN
⁸Integrated Biomedical Sciences Program, University of Tennessee Health Science Center, Memphis, TN
⁹Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children’s Research Hospital, Memphis, TN

Vera M Poort^1,2*, Rico Hagelaar, MSc^1,3*, Diego Montiel González, MSc^1,3*, Jessica G.C.A.M. Buijs-Gladdines^3*, Laurianne Trabut, MSc^1,3*, Bram van Wijk, PhD^4*, Jules PP Meijerink, PhD^3,5 and Ruben Van Boxtel, PhD^1,3*

¹Oncode Institute, Utrecht, Netherlands
²Princess Maxima Center For Paediatric Oncology, Utrecht, Netherlands
³Princess Máxima Center for Pediatric Oncology, Utrecht, Netherlands
⁴Wilhelmina Children's Hospital (WKZ), University Medical Center Utrecht, Utrecht, Netherlands
⁵Acerta Pharma B.V., Oss, Netherlands

Amin Sobh, PhD¹, Charlotte L Kaestner, BS¹, Alberto Riva, PhD^2*, Karthik Vasan^3*, Alisha Patel^1*, Greeshma Surapaneni^1*, Janai Poullard^1*, Elena Encinas^1*, Richard Lynn Bennett, PhD¹, Constantine S. Mitsiades, MD, PhD⁴, Lawrence H. Boise, PhD⁵, Navdeep S. Chandel, PhD^3* and Jonathan D. Licht, MD¹

¹Department of Medicine, University of Florida, Gainesville, FL
²Interdisciplinary Center for Biotechnology Research, University of Florida, Gainesville, FL
³Northwestern University, Chicago, IL
⁴Dept. of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
⁵Emory University, Atlanta, GA

Xuxiang Liu, PhD^1*, Kunal Shetty, BS^1*, Yuping Li, Ph.D.^1*, Jibin Zhang, Ph.D.^1*, Alyssa C. Bouska, Ph.D.^2*, Javeed Iqbal, Ph.D.^2*, Giorgio Inghirami, MD^3* and Wing C. Chan, MD¹

¹Department of Pathology, City of Hope National Medical Center, Duarte, CA
²Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE
³Weill Cornell Medicine, New York, NY

Rachel Wong^1*, Samuel Gusscott, PhD^1*, Gabriela Cristina Segat, MSc^1*, Annaick Carles, PhD^2*, Reanne Bowlby, MSc^1*, Martin Hirst, PhD^2* and Andrew P. Weng, MD³

¹BC Cancer Agency, Vancouver, Canada
²University of British Columbia, Vancouver, Canada
³Terry Fox Laboratory, BC Cancer Agency, Vancouver, BC, Canada

Kota Yoshifuji, MD, PhD^1*, Yotaro Motomura, M.D.^1*, Makiko Saito, M.D.^1*, Ayako Nogami, M.D., Ph.D.², Genji Kawade^3*, Shiori Watabe^3*, Kouhei Yamamoto, M.D., Ph.D.^3*, Takehiko Mori, M.D., Ph.D.^1* and Toshikage Nagao, M.D., Ph.D.^1*

¹Department of Hematology, Tokyo Medical and Dental University (TMDU), Tokyo, Japan
²Department of Laboratory Medicine, Tokyo Medical and Dental University (TMDU), Tokyo, Japan
³Department of Comprehensive Pathology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan

Junbin Huang^1*, Jing Yang^2*, Yun Chen, PhD^3,4*, Zhizhuang Joe Zhao, PhD^4,5 and Chun Chen, MD, PhD^4*

¹Sun Yat-Sen University, Shenzhen, China
²pediatric, the seventh affiliated hospital, Sun Yat-sen University, shenzhen, China
³Moores Cancer Center, University of California, San Diego, La Jolla, CA
⁴The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, China
⁵Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK