Thijs van Bergen, MD^1*, Anna Aalbers, MD, PhD^2,3, Dennis Bosch, BSc^4*, Onno Roovers, BSc^4*, Akiko Shimamura, MD, PhD^5*, Marc H.G.P. Raaijmakers, MD^6,7, Peter E. Newburger, MD⁸ and Ivo P Touw, PhD⁴

¹Hematology, Erasmus University Medical Center, Rotterdam, Netherlands
²Erasmus MC, Rotterdam, Netherlands
³Hematology, Erasmus University Medical Center, Rotterdam, NLD
⁴Department of Hematology, Erasmus MC, Rotterdam, Netherlands
⁵Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA
⁶Erasmus Medical Center Cancer Institute, Rotterdam, NLD
⁷Erasmus Medical Center, Rotterdam, NLD
⁸University of Massachusetts Medical School, Worcester, MA

Sara L. Seegers, MSc^1*, Amanda Lance, MS^1*, Steven I. Park, MD², Belinda R. Avalos, MD¹ and Lawrence J Druhan, PhD¹

¹Department of Hematologic Oncology and Blood Disorders, Levine Cancer Institute, Atrium Health, Charlotte, NC
²Department of Hematologic Oncology and Blood Disorders, Levine Cancer Institute, Charlotte, NC

Jinhu Zou^*, Xuefeng Gao^*, Chengxing Zhou^*, Zelong Gong, PhD^*, Xiaolong He, PhD^*, Min Long, PhD^* and Hong Cao, MD, PhD^*

Department of Microbiology, School of Public Health (Guangdong Provincial Key Laboratory of Tropical Disease Research), Southern Medical University, Guangzhou, China

Joe West^1,2,3,4*, Peter Stilwell^4*, Hanhua Liu, PhD^4*, Lu Ban, PhD^5*, Mary Bythell^4*, Timothy Card^3,6*, Peter Lanyon^3,4*, Vasanta Nanduri^7*, Judith Rankin^4,8*, Mark Bishton, PhD, MBChB^4,6,9 and Colin Crooks^2,3,4*

¹Aarhus University, Aarhus, United Kingdom
²University of Nottingham, Nottingham, GBR
³Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom
⁴National Disease Registration Service, NHS Digital, United Kingdom
⁵PPD Ltd, Beijing, China
⁶University of Nottingham, Nottingham, United Kingdom
⁷Watford General Hospital, Watford, GBR
⁸University of Newcastle, Newcastle, GBR
⁹Nottingham University Hospitals, Nottingham, United Kingdom

Alexandra B Ysasi, BS^1*, Anna Engler, PhD^2*, Carlos Villacorta-Martin, MSc^2*, Riley Pihl^3*, Anna C Belkina, PhD^3* and George J Murphy, PhD^2,4

¹Center for Regenerative Medicine (CReM), Boston University School of Medicine, Boston, RI
²Center for Regenerative Medicine (CReM), Boston University School of Medicine, Boston, MA
³Department of Pathology, Boston University School of Medicine, Boston, MA
⁴Section of Hematology and Medical Oncology, Boston University School of Medicine, Boston, MA

Usua Oyarbide, PhD¹, Jillian Kodger, MS^2*, Sofia del Rio^3*, Yana Sandlers, PhD^4* and Seth J. Corey, MD^5,6

¹Department of Cancer Biology, Cleveland Clinic, Cleveland, OH
²Clinical/Bioanalytical Chemistry, Cleveland State University, Cleveland, OH
³Cancer Biology, Cleveland Clinic, Cleveland, OH
⁴Chemistry, Cleveland State University, Cleveland, OH
⁵Departments of Pediatrics and Cancer Biology, Cleveland Clinic, Cleveland, OH
⁶Pediatrics and Cancer Biology, Cleveland Clinic, Cleveland, OH

Kylle M. Tollefsen, PhD^*, Lori Neri, MSN, APN-BC^*, Shariq Ali, PhD and Diego Cadavid, MD, FAAN, FANA^*

X4 Pharmaceuticals, Inc., Boston, MA

Vera Bzhilyanskaya, BS^1*, Ronald J. Meis, PhD^2*, Narda Theobald, BS^3*, Tyra Estwick^4*, Hong Lei^1*, Steven Highfill, PhD^5*, David F. Stroncek, MD^5*, Leonard Chen, MD, PhD^6*, Kamille West-Mitchell, MD^6*, Gary A. Dahl, PhD^2*, Harry L Malech, MD³, Suk See De Ravin, MD, PhD^3,7* and Julie Brault, PhD, PharmD^8*

¹National Institutes of Health, Bethesda
²CELLSCRIPT, LLC, Madison, WI
³Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD
⁴NIH, Bethesda
⁵Center for Cellular Engineering, National Institutes of Health, Bethesda, MD
⁶Department of Transfusion Medicine, National Institutes of Health, Bethesda, MD
⁷Laboratory of Clinical Immunology and Microbiology,NIAID, NIH, Bethesda, MD
⁸Ridgeline Discovery GmbH, Basel, Switzerland

Jie Chen^*, Jinhu Zou^*, Yu Wan^*, Xuefeng Gao^*, Pengwei Huang^*, Zixuan Wang^* and Hong Cao, MD, PhD^*

Department of Microbiology, School of Public Health (Guangdong Provincial Key Laboratory of Tropical Disease Research), Southern Medical University, Guangzhou, China

Iris Karkempetzaki, MSc^1,2*, Irene Mavroudi, PhD^1,2*, Grigorios Tsaknakis, PhD^1,2*, Dimitra Nikoleri^3,4*, Spiros Georgakis, PhD^3,4*, George Bertsias, MD, PhD^3,4*, George Goulielmos, PhD^5*, Akrivi Chrysanthopoulou^6*, Panagiotis Skendros, MD, PhD^6*, Konstantinos Ritis, MD, PhD^6* and Helen A. Papadaki, MD^1,2

¹Haemopoiesis Research Laboratory, School of Medicine, University of Crete, Heraklion, Greece
²Department of Hematology, University Hospital of Heraklion, Heraklion, Greece
³Laboratory of Rheumatology, Autoimmunity and Inflammation, School of Medicine, University of Crete, Heraklion, Greece
⁴Infections and Immunity, Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology – Hellas (FORTH), Heraklion, Greece
⁵Department of Internal Medicine, Section of Molecular Pathology and Human Genetics, School of Medicine, University of Crete, Heraklion, Greece
⁶First Department of Internal Medicine and Laboratory of Molecular Hematology, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis, Greece

Rachelle Thompson^1*, Megan Zoltowski^2*, Derick Lim^2*, Caroline Diorio, MD³, Elizabeth Margolskee, MD^4*, Michele Paessler, D.O.^5*, Veronica Bochenek^6*, Edward M Behrens, MD^7*, David T. Teachey, MD⁸, Hamid Bassiri, MD PhD^9*, Michele P. Lambert, MD¹⁰ and Kandace Gollomp, MD¹¹

¹The State University of New York Downstate Health Sciences University, Brooklyn, NY
²Department of laboratory medicine, The Children's Hospital of Philadelphia, Philadelphia, PA
³Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA
⁴The Children's Hospital of Philadelphia, Philadelphia, PA
⁵Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA
⁶Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA
⁷Division of Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, PA
⁸Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Rutledge, PA
⁹Division of Infectious Diseases, The Children's Hospital of Philadelphia, Philadelphia, PA
¹⁰Children's Hosp. of Phila., Philadelphia, PA
¹¹Department of Pediatrics, University of Pennsylvania PSOM, Philadelphia, PA

Pengwei Huang^*, Xuefeng Gao^*, Jinhu Zou^*, Jie Chen^*, Xiaolong He, PhD^*, Min Long, PhD^* and Hong Cao, MD, PhD^*

Department of Microbiology, School of Public Health (Guangdong Provincial Key Laboratory of Tropical Disease Research), Southern Medical University, Guangzhou, China

Kirstine Kløve-Mogensen^1,2*, Rudi Steffensen, PhD^2*, Tania Nicole Masmas, MD, PhD^3*, Petter Hoglund, MD, PhD^4*, Andreas Glenthøj, MD, PhD⁵, Thure Haunstrup, MD^2*, Paul Ratcliffe, M.Sc^4*, Henrik Hasle, MD, PhD⁶ and Kaspar Rene Nielsen, MD, PhD^1,2

¹Clinical Medicine, Aalborg University, Aalborg, Denmark
²Clinical Immunology, Aalborg University Hospital, Aalborg, Denmark
³Pediatric Hematopoietic Stem Cell Transplantation and Immunodeficiency, Copenhagen University Hospital, Copenhagen, Denmark
⁴Department of medicine Huddinge, Karolinska Institute, Stockholm, Sweden
⁵Department of Hematology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
⁶Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark

Jacob R. Bledsoe^1*, Marine Delecourt-Billet, PharmD^2*, Merideth L. Kelley, MS^3*, Odile Fenneteau, PharmD^2*, Christoph B. Geier, MD, MSc^4*, Jadee Neff^5*, Melis Yilmaz, MMSc^6,7*, Inga Sakovich, MSc^8*, Svetlana Sharapova, PhD^8*, Lori Neri, MSN, APN-BC^9*, Viviana Moschese, MD, PhD, MsSC^10*, Jolan E. Walter, MD, PhD^7,11,12*, Mirta Cavieres, MD^13*, Daigo Akahane, MD, PhD^14*, Talal Mousallem, MD^15*, Teresa Tarrant, MD^16*, Julie Li, MD, PhD^17*, Audrey Anna Bolyard, RN, BS^3*, Alessandro Mauriello, MD^18*, Katja Sockel, MD^19*, Peter E. Newburger, MD²⁰, Jean Donadieu, MD^21,22* and David C. Dale, MD³

¹Department of Pathology, Boston Children's Hospital, Boston, MA
²Service d’Hématologie Biologique, Hôpital Robert-Debré, AP-HP, Paris, France
³Department of Medicine, University of Washington, Seattle, WA
⁴Department of Rheumatology and Clinical Immunology, Center for Chronic Immunodeficiency (CCI), University Medical Center Freiburg, Freiburg, Germany
⁵Department of Pathology, Duke University Health System, Durham, NC
⁶Division of Allergy and Immunology, Departments of Pediatrics and Medicine, University of South Florida Morsani College of Medicine, St. Petersburg, FL
⁷Division of Allergy and Immunology, Departments of Pediatrics, Johns Hopkins All Children's Hospital, St. Petersburg, FL
⁸Research Department, Belarusian Research Center for Pediatric Oncology, Hematology and Immunology, Minsk, Belarus
⁹X4 Pharmaceuticals, Inc., Boston, MA
¹⁰Department of Pediatrics, Policlinico Tor Vergata, Tor Vergata University, Rome, Italy
¹¹Division of Allergy and Immunology, Massachusetts General Hospital for Children, Boston, MA
¹²Division of Allergy and Immunology, Departments of Pediatrics and Medicine, University of South Florida Morsani College of Medicine, Tampa, FL
¹³Hematology Unit, Dr. Luis Calvo Mackenna Children’s Hospital, Santiago, Chile
¹⁴Department of Hematology, Tokyo Medical University, Tokyo, Japan
¹⁵Division of Allergy & Immunology, Department of Pediatrics, Duke University, Durham, NC
¹⁶Division of Rheumatology and Immunology, Department of Medicine, Duke University, Durham, NC
¹⁷Pathology & Laboratory Medicine, Boston University School of Medicine, Boston, MA
¹⁸Department of Pathology, Policlinico Tor Vergata, Tor Vergata University, Rome
¹⁹Medical Clinic and Policlinic I, University Hospital Dresden, TU Dresden, Dresden, Germany
²⁰Departments of Pediatrics and Molecular, Cell, and Cancer Biology, Pediatric Hematology/Oncology Division, Worcester, MA
²¹Department of Pediatric Hematology-Oncology, Reference Center for Chronic Neutropenia, National Registry of Congenital Neutropenia, Paris, France
²²Sorbonne University, Armand Trousseau Hospital APHP, Paris, France

Catherine M. Broome, MD¹, Jon P. Fryzek, MPH, PhD^2*, Lauren C. Bylsma, MPH^2*, Meghan E. Mitchell, MPH^2*, Nawar M. Shara, PhD^3*, Stephen J. Fernandez, MPH^3*, Joseph P. Catlett, MD³, Todd L. Edwards, MS, PhD^4*, Daniel J. Hausrath, MD⁴, Loren P. Lipworth, ScD^4*, Jacob S. Lai, PhD^5*, Kathy Dong, PharmD, MBA^6*, Naval Daver, MD⁷ and Carl E. Allen, MD, PhD⁸

¹Division of Hematology, MedStar Georgetown University Hospital, Washington, DC
²EpidStrategies, Rockville, MD
³MedStar Health Research Institute, Hyattsville, MD
⁴Vanderbilt University Medical Center, Nashville, TN
⁵Electra Therapeutics, Saratoga, CA
⁶Electra Therapeutics, South San Francisco, CA
⁷Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
⁸Division of Pediatric Hematology and Oncology, Baylor College of Medicine, Houston, TX