-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

113. Hemoglobinopathies, Excluding Thalassemia: Basic and Translational: Poster II

Symposia: Hemoglobinopathies, Excluding Thalassemia: Basic and Translational Program: Oral and Poster Abstracts
Type: Poster
Sunday, December 11, 2022: 6:00 PM-8:00 PM
Hall D (Ernest N. Morial Convention Center)

Helen Fogarty, MBBCHBAO1,2,3, Soracha Ward4*, Ellie Karampini, PhD4*, Azaz Ahmad, PhD5*, Gemma Leon, PhD3*, Aisling Rehill, PhD6*, Rosena Geoghegan1*, Helena Conroy1*, Noel Ngwenya7*, Mary Byrne8*, Ulrich Budde, MD, PhD9, Sonja Schneppenheim, MD, PhD10*, Emma Tuohy, MD7*, Corrina McMahon, MD, PhD11* and James O'Donnell, MD, PhD2,12,13*

1Department of Haematology, Children’s Health Ireland (CHI) at Crumlin, Dublin, Ireland
2National Children’s Research Centre, Children’s Health Ireland (CHI) at Crumlin, Dublin, Ireland
3Irish Centre for Vascular Biology, Royal College of Surgeons in Ireland, Dublin, Ireland
4Department of Vascular Biology, Royal College of Surgeons in Ireland, Dublin, Ireland
5Irish Centre for Vascular Biology, Royal College of Surgeons In Ireland, Dublin 2, IRL
6Irish Centre for Vascular Biology, Royal College of Surgeons In Ireland, Dublin, IRL
7Department of Haematology, St James's Hospital, Dublin, Ireland
8National Coagulation Centre, St James's Hospital, Dublin 8, Ireland
9MEDILYS Labor Gesellschaft, Hamburg, DEU
10Medilys Laborgesellschaft Mbh, Hamburg, DEU
11Department of Haematology, Children’s Health Ireland at Crumlin, Crumlin, Ireland
12Irish Centre for Vascular Biology, Royal College of Surgons in Ireland, Dublin, Ireland
13National Coagulation Centre, St James’s Hospital, Dublin, Ireland

Kobina Dufu, PhD1*, Donna Oksenberg, PhD1*, Brian E Cathers, PhD1*, Carlos J Munoz, MS2*, Cynthia R Muller, PhD2* and Pedro Pedro Cabrales, PhD2*

1Global Blood Therapeutics, South San Francisco, CA
2University of California, San Diego, La Jolla, CA

Kobina Dufu, PhD1*, Donna Oksenberg, PhD1*, Brian E Cathers, PhD1*, Carlos J Munoz, MS2*, Cynthia R Muller, PhD2* and Pedro Pedro Cabrales, PhD2*

1Global Blood Therapeutics, South San Francisco, CA
2University of California, San Diego, La Jolla, CA

Fabio H Silva1*, Carolina Oliveira Splendore1*, Fabiano B Calmasini, PhD2* and Fernando Ferreira Costa, M.D., Ph.D.3

1Sao Francisco University, Braganca Paulista, Brazil
2University of Campinas, Campinas, Brazil
3Hematology and Hemotherapy Center, University of Campinas, Campinas, SP, Brazil

Stephen C Rogers, PhD1*, Parikshit Moitra, PhD2*, Mary Brummet1*, Zohreh Safari, PhD1*, Qihong Wang, MD1*, Joy Okhuevbie, BS1*, Nancy Anabaraonye3*, Osheiza Y. Abdulmalik, DVM4*, Martin K. Safo, PhD5*, Nicole Glynn-Cunningham, RN6*, Jennie Y. Law, MD7, Maria R. Baer, MD8, Dipanjan Pan, PhD9* and Allan Doctor, MD1

1Center for Blood Oxygen Transport and Hemostasis, University of Maryland School of Medicine, Baltimore, MD
2Department of Bioengineering, Pennsylvania State University School of Engineering, University Park, PA
3Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA
4Division of Hematology, The Children’s Hospital of Philadelphia, Philadelphia, PA
5Institute for Structural Biology, Drug Discovery and Development, Virginia Commonwealth University, Richmond, VA
6Department of Hematology, University of Maryland Medical Center, Baltimore, MD
7Department of Medicine, University of Maryland School of Medicine, Baltimore, MD
8University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, MD
9School of Engineering; Huck Institutes for the Life Sciences, Pennsylvania State University, University Park, PA

Kunhua Qin1*, Peng Huang, PhD1*, Xianjiang Lan, PhD2,3*, Megan S. Saari, BS1*, Eugene Khandros, MD, PhD1, Osheiza Y. Abdulmalik, DVM1*, Cheryl A. Keller, PhD4*, Belinda M. Giardine4*, Ross C. Hardison, PhD4*, Junwei Shi, PhD5* and Gerd A. Blobel, MD, PhD1,6

1Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA
2Department of Systems Biology for Medicine, School of Basic Medical Sciences, Fudan University, Shanghai, China
3Liver Cancer Institute, Zhongshan Hospital, Shanghai, China
4Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA
5Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
6Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA

Ruben Yiqi Luo, PhD1*, Carolyn Wong, CLS2*, James Qiangwei Xia, PhD3*, Bert Glader, MD, PhD4, Run-Zhang Shi, PhD1* and James L Zehnder, MD5

1Pathology, Stanford University, Palo Alto, CA
2Stanford Health Care, Palo Alto, CA
3CMP Scientific, Brooklyn, NY
4Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA
5Department of Pathology, Stanford University School of Medicine, Stanford, CA

Namita Kumari, PhD1*, Asrar Ahmad, PhD2,3*, Clemilson Berto-Junior, PhD4*, Andrey Ivanov, PhD5*, Fayuan Wen, Ph.D4*, Sharmin Diaz, NP6*, James G. Taylor, MD4, Marina Jerebtsova, PhD7 and Sergei Nekhai, PhD8

1Sickle Cell Center, Howard University, Washington, DC
2Howard University, Washington DC, DC
3Howard University, Center for Sickle Cell Disease, Washington DC, DC
4Center for Sickle Cell Disease, Howard University, Washington, DC
5Center for Sickle Cell Disease, Howard University, Washington DC, DC
6Medicine, Howard University, Washington DC, DC
7Department of Microbiology, Howard University, McLean, VA
8Center for Sickle Cell Disease and Department of Medicine, Howard University Center for Sickle Cell Disease, Washington, DC

Nirupama Ramadas, PhD1*, Kailyn Lowder1*, Laurent O. Mosnier, PhD2, Rafal Pawlinski, PhD3 and Erica Sparkenbaugh, PhD1

1Blood Research Center, Division of Hematology, University of North Carolina Chapel Hill, Chapel Hill, NC
2Department of Molecular Medicine, The Scripps Research Inst., La Jolla, CA
3Blood Research Center, Division of Hematology, University of North Carolina, Chapel Hill, NC

Malini Sharma, BA1*, Timothy Lequang, MSc2, Brian J Philips, PhD2*, Fabliha A Chowdhury, MSc2,3*, Katherine C Wood, PhD2, Adam C Straub, PhD2,3* and Julia Z Xu, MD, MS2,4

1University of Pittsburgh School of Medicine, Pittsburgh, PA
2Heart, Lung, Blood and Vascular Medicine Institute, Department of Medicine, University of Pittsburgh, Pittsburgh, PA
3Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA
4Department of Medicine, University of Pittsburgh, Pittsburgh, PA

Celeste K. Kanne, MS1*, Christina Liu1*, Britney N. Hernandez1*, Erica N. Evans1, Mira P. Pochron, PhD2*, Kobina Dufu, PhD2* and Vivien A. Sheehan, MD, PhD1

1Aflac Blood and Cancer Center, Children’s Healthcare of Atlanta, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA
2Global Blood Therapeutics, South San Francisco, CA

Kang Le, PhD1*, Xunde Wang, PhD1*, Maureen Lundt, MSc1*, Anna Conrey, NP1*, Ingrid Frey, RN, BSN, MS1*, Silvia Giannini, PhD2, Penelope A. Kosinski, MS3*, John A. Hausman4*, Philip S. Low, PhD4*, Neal Jeffries, PhD5* and Swee Lay Thein, MBBS, DSc, FRCP, FRCPath, MRCP, MRCPath1

1Sickle Cell Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
2Agios Pharmaceuticals, Inc., Brookline, MA
3Agios Pharmaceuticals, Inc., Cambridge, MA
4Purdue University, West Lafayette, IN
5National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD

Miguel Brito, PhD1*, Catarina Ginete, MSc2*, Joana Ferreira, BSc2*, Manuela Mendes3*, Jocelyne Vasconcelos, MSc4*, Mariana Delgadinho, MSc2*, Cruz Santos, PhD4*, Francisco Quinto, MD3*, Fernanda Simão, MD3*, Anabela Mateus, BSc4* and Filipe Fernandes2*

1Escola Superior de Tecnologia da Saúde de Lisboa, Lisbon, AL, Portugal
2Escola Superior de Tecnologia da Saúde de Lisboa, Lisbon, Portugal
3Maternidade Lucrécia Paím, Luanda, Angola
4Centro de Investigação em Saúde de Angola, Luanda, Angola

Alessandro Mattè1*, Antonio Recchiuti2*, Enrica Federti1*, Filippo Mazzi1*, Jacopo Ceolan1*, Annamaria Porreca2*, Marta Di Nicola2*, Sofia Menotti1*, Stefano Alivernini3*, Carlo Brugnara, MD4 and Lucia De Franceschi, MD1

1University of Verona and AOUI Verona, Verona, Italy
2"G. D'Annunzio" University of Chieti - Pescara, Chieti, ITA
3Institute of Rheumatology, Università Cattolica del Sacro Cuore & Fondazione Policlinico Gemelli, Rome, Italy
4Department of Laboratory Medicine, Harvard Medical School, Boston Children's Hospital, Boston, MA

Zoe Sekyonda, BS1*, Utku Goreke, MSc2*, Ran An, PhD2, Solomon Oshabaheebwa, MSc1*, Yuncheng Man, PhD2* and Umut A. Gurkan, PhD1,2,3

1Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH
2Department of Mechanical & Aerospace Engineering, Case Western Reserve University, Cleveland, OH
3Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH

Alka A. Potdar, PhD1*, Michael Caponegro, PhD2*, Onuralp Soylemez, PhD1*, Anupama Reddy, PhD2* and Karen Yu, PhD1*

1Global Blood Therapeutics, South San Francisco, CA
2Vindhya Data Science, Morrisville, NC

Carlos J Munoz, MS1*, Cynthia R Muller, PhD1*, Daniela Lucas, BS1*, Ivan Susin Pires, BS2*, Andre F Palmer, PhD2*, Srila Gopal, MD3 and Pedro Cabrales, PhD1*

1Department of Bioengineering, University of California San Diego, La Jolla, CA
2William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, OH
3University of California San Diego, La Jolla, CA

*signifies non-member of ASH