Luis E. E. Aguirre, MD¹, Najla Al Ali, MS², Akriti G Jain, MD³, Onyee Chan, MD^1*, Somedeb Ball, MD¹, Andrew Kuykendall, MD¹, Kendra Sweet, MD¹, Jeffrey E. Lancet, MD¹, Eric Padron, MD¹, Rami S. Komrokji, MD¹ and David A. Sallman, MD²

¹Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
²Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL
³Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, WESLEY CHAPEL, FL

Guillermo Montalban-Bravo, MD¹, Faezeh Darbaniyan, PhD^2*, Kelly S. Chien, MD¹, Danielle Hammond, MD¹, Rashmi Kanagal-Shamanna, MD³, Tapan M. Kadia, MD¹, Courtney D. DiNardo, MD, MSCE¹, Naval Daver, MD¹, Farhad Ravandi, MD¹, Elias Jabbour, MD¹, Naveen Pemmaraju, MD¹, Nicholas Short, MD⁴, Koichi Takahashi, MD, PhD⁴, Zeev E. Estrov, MD¹, Sherry A. Pierce, BSN, BA^1*, Hagop Kantarjian, MD⁵ and Guillermo Garcia-Manero, MD⁶

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
⁴Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX
⁵Department of Leukemia, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
⁶Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX

Rami S. Komrokji¹, Najla Al Ali, MS², Somedeb Ball, MD^1*, Onyee Chan, MD^3*, Andrew Kuykendall, MD¹, Kendra Sweet, MD¹, Jeffrey E. Lancet, MD^1,2, Eric Padron, MD² and David A. Sallman, MD²

¹Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
²Department of Malignant Hematology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL
³Department of Malignant Hematology, H. Lee Moffitt Cancer Center & Research Institute, TAMPA, FL

Robert E. Briski, MD¹, Kelly S. Chien, MD², Guillermo Montalban-Bravo, MD², Tapan M. Kadia, MD³, Elias Jabbour, MD², Naveen Pemmaraju, MD², Koji Sasaki, MD², Danielle Hammond, MD², Nicholas Short, MD⁴, Farhad Ravandi, MD², Yesid Alvarado, MD², Sherry A. Pierce, BSN, BA^2*, Guillermo Garcia-Manero, MD⁵ and Hagop Kantarjian, MD⁶

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, AL
²Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Leukemia, MD Anderson Cancer Center, Houston, TX
⁴Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX
⁵Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX
⁶Department of Leukemia, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX

Miao Miao, MD^1*, Depei WU^1*, Shuangfeng Xie, PhD^2*, Mei Hong, MD^3*, ChunKang Chang, PhD^4*, Li Yu, MD^5*, Sujun Gao, PhD^6*, Yan Li, MD^7*, Yuhua Li, MD & PhD⁸, Zunmin Zhu, MD^9*, Baolin Tang^10*, Bingzong Li, MD, PhD¹¹, Haiping Yang, MD^12*, Jishi Wang, PhD¹³, Ling Qin^14*, Rong Fu, PhD^15*, Fei Li^16*, Liangming Ma, MD^17*, Qifa Liu, MD¹⁸, Xin Du, PhD^19*, Zhongxing Jiang, MD^20*, Zhenyu Li, M.D., Ph.D.^21*, Aijun Liu, MD^22*, Hongyan Tong, MD^23*, Jun Ma, MD^24*, Li Liu, MD^25*, Qingchi Liu^26*, Yajing Xu, MD&PhD²⁷, Hui Zhou, MD&PhD^28*, Yan Wang, MD^28*, Jianlin Chen^28*, Ziru Niu^28*, Mingxia Chen^28* and Zhijian Xiao, MD&PhD^29*

¹The First Affiliated Hospital of Suzhou University, Suzhou, China
²Sun Yixian Hospital of Sun Yat sen University, Guangzhou, China
³Insititute of Haematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
⁴Shanghai Sixth Hospital, Shanghai, China
⁵The Second Affiliated Hospital of Nanchang University, Nanchang, China
⁶Department of Hematology, The First Hospital of Jilin University, Changchun, China
⁷The First Affiliated Hospital of China Medical University, Shenyang, China
⁸Zhujiang Hospital of Southern Medical University, Guangzhou, China
⁹Henan Provincial People's Hospital, Zhengzhou, China
¹⁰The First Affiliated Hospital Of USTC & Anhui Provincial Hospital, Hefei, China
¹¹The Second Affiliated Hospital of Suzhou University, Suzhou, China
¹²Department of Hematology, The First Affiliated Hospital of Henan University of Science and Technology, Luoyang, China
¹³Affiliated Hospital of Guizhou Medical University, Guiyang, China
¹⁴The First Affiliated Hospital of Henan University of Science and Technology, Luoyang, China
¹⁵Tianjin Medical University General Hospital, Tianjin, China
¹⁶The First Affiliated Hospital of Nanchang University, Nanchang, China
¹⁷Shanxi Baiqiuen Hospital, Taiyuan, China
¹⁸Nanfang Hospital of Southern Medical University, Guangzhou, China
¹⁹Guangdong Provincial People's Hospital, Guangdong, China
²⁰Department of Hematology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
²¹The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China
²²Beijing Chaoyang Hospital, Beijing, China
²³The First Affiliated Hospital of Medical College of Zhejiang University, Hangzhou, China
²⁴Harbin First Hospital & Hematological Tumor Research Center of Harbin First Hospital, Harbin, China
²⁵Tangdu Hospital Affiliated to the Fourth Military Medical University, Xi'an, China
²⁶Department of Hematology, The First Hospital of Hebei Medical University, Shijiazhuang, China
²⁷XiangYa Hospital Central South University, Hunan, China
²⁸Innovent Biologics (Suzhou) Co., Ltd., Beijing, China
²⁹MDS and MPN Centre, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China

Amer M. Zeidan, MD¹, Victoria Divino, BA^2*, Mitch DeKoven, MHSA^2*, Elizabeth Wang, MS^2*, Justin Chen, BPharm, MHS^2*, Tehseen Salimi, MD, MHA^3* and Robert S. Epstein, MD, MS^4*

¹Hematology, Yale University and Yale Cancer Center, New Haven, CT
²Health Economics and Outcomes Research, IQVIA, Falls Church, VA
³Medical Affairs and Real-World Evidence, Taiho Oncology, Inc., Princeton, NJ
⁴Epstein Health, Woodcliff Lake, NJ

Jozal W. Moore, MD¹, Jason H. Mendler, MD, PhD¹, Kah Poh (melissa) Loh, MD¹, Mitra Azadniv, PhD^2*, Kristen M. O'Dwyer, MD¹, Eric J. Huselton, MD¹, Frank Akwaa, MD^1*, Benjamin J. Frisch, PhD³, Myla Strawderman, MS^2*, Mark W. LaMere, BA^4*, Daniel K. Byun, BS^4*, Alyssa C. Jasper, BA^2*, Michael W. Becker, MD¹, Jane L. Liesveld, MD¹ and Laura M. Calvi, MD⁵

¹Wilmot Cancer Institute, Division of Hematology and Oncology, University of Rochester Medical Center, Rochester, NY
²Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY
³Department of Pathology, University of Rochester Medical Center, Rochester, NY
⁴University of Rochester Medical Center, Rochester, NY
⁵Wilmot Cancer Institute, Division of Endocrinology and Metabolism, University of Rochester Medical Center, Rochester, NY

Jyoti Kumar, MD, MS^1*, Vishesh Khanna, MD², Rong Lu, PhD^3*, Henning Stehr, PhD^4*, Michael A Spinner, MD⁵, Oscar Silva, MD, PhD^4*, Sebastian Fernandez-Pol, MD, PhD^4*, Jean S Oak, MD, PhD^4*, Peter L Greenberg, MD⁶ and Brent Tan, MD, PhD^4*

¹Department of Pathology, Stanford University School of Medicine, Palo Alto, CA
²Division of Hematology, Department of Medicine, Stanford University Medical Center, Palo Alto, CA
³Department of Medicine, Quantitative Sciences Unit, Stanford University School of Medicine, Stanford, CA
⁴Department of Pathology, Stanford University School of Medicine, Stanford, CA
⁵Division of Hematology, Department of Medicine, Stanford University Medical Center, Stanford, CA
⁶Department of Medicine, Division of Hematology, Stanford University School of Medicine, Stanford, CA

Daniel I Nathan, MD¹, David Mueller, MD^2*, Angela Liu, MD^1*, John Mascarenhas, MD¹ and Bridget K Marcellino, MD, PhD¹

¹Tisch Cancer Institute, Division of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY
²Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY

Junying Wu^1*, Wenjun Zhang^1*, Peihong Zhang^2*, Tiejun Qin^3*, Zefeng Xu^1,3*, Qi Sun^2*, Yujiao Jia, MD^2*, Shiqiang Qu^1,3*, Bing Li^1,3*, Huijun Wang^2*, Lijuan Pan^3*, Jinqin Liu^1*, Yudi Zhang, PhD^1*, Xin Yan, MD^1*, Robert Peter Gale⁴ and Zhijian Xiao, MD&PhD^5,6,7*

¹State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
²Hematologic Pathology Centre, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
³MDS and MPN Centre, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
⁴Centre for Haematology Research, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom
⁵State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
⁶MDS and MPN Centre, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China
⁷Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China

Ami B. Patel, MD¹, Afaf Osman, MD¹, Tony D. Pomicter, MS^2*, Srinivas K. Tantravahi, MBBS² and Michael W. Deininger, MD, PhD³

¹Division of Hematology and Hematologic Malignancies, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT
²Huntsman Cancer Institute, University of Utah, Salt Lake City, UT
³Division of Hematology and Hematologic Malignancies, University of Wisconsin Milwaukee, Milwaukee, WI

Wanshu Chen^1*, Bing Han, MD^1* and Zhao Wang, MD²

¹Peking Union Medical College Hospital, Beijing, China
²Department of Hematology, Beijing Friendship Hospital, Capital Medical University, Beijing, China

Youshan Zhao^1* and ChunKang Chang, PhD^2*

¹Department of Hematology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China
²Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai, China

Dina Elantably, MD^1*, Jiasheng Wang, MD², Abdul Rahman Al Armashi, MD^2*, Nabil El Hage Chehade, MD^1* and Akram Alkrekshi, MD^3*

¹Department of Internal Medicine, Case Western Reserve University MetroHealth Medical Center, Cleveland, OH
²Department of Hematology and Oncology, Seidman Cancer Center, University Hospitals Cleveland Medical Center, Cleveland, OH
³Department of Internal Medicine, Case Western Reserve University MetroHealth Medical Center, Westlake, OH

Elisabeth Weiß, PhD^*, Torsten Haferlach, MD, Constance Baer, PhD, Manja Meggendorfer, PhD, Claudia Haferlach, MD and Wolfgang Kern, MD

MLL Munich Leukemia Laboratory, Munich, Germany

Amer M. Zeidan, MD¹, Amy E. DeZern, MD², Uma Borate, MD³, Krissy Kobata^4*, Susan E. Ide, PhD^5*, John Sabo^5*, Pedro Marques Ramos, PhD^6*, Haiying Sun^5*, Roger M. Lyons, MD⁷ and Guillermo Garcia-Manero, MD⁸

¹Yale University, New Haven, CT
²Johns Hopkins University, Baltimore, MD
³Oregon Health & Science University, Portland, OR
⁴Los Angeles, CA
⁵Novartis Pharmaceuticals Corporation, East Hanover, NJ
⁶Novartis Pharma AG, Basel, Switzerland
⁷Texas Oncology and US Oncology Research, San Antonio, TX
⁸The University of Texas MD Anderson Cancer Center, Houston, TX

Kristin L Koenig, MD¹, Prachi Jain, MBBS^2*, Ying Huang, MS, MA^1*, Kerry A. Rogers, MD³, Seema A. Bhat, MD¹, Jennifer A. Woyach, MD¹, Michael R. Grever, MD⁴, Uma Borate, MD⁵, Alice S. Mims, MD¹, Daniel Jones, MD, PhD⁶, Cecelia Miller, PhD^7*, James S. Blachly, MD¹ and Adam S Kittai, MD¹

¹Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH
²Department of Internal Medicine, Division of Hematology, The Ohio State University Wexner Medical Center, Columbus, OH
³Ohio State University Hospital, Columbus, OH
⁴Department of Internal Medicine, Division of Hematology, Wexner Medical Center at Ohio State University, Columbus, OH
⁵Division of Hematology, The Ohio State University, Columbus, OH
⁶Department of Pathology, The Ohio State University, Columbus, OH
⁷Department of Pathology, The Ohio State University, Pickerington, OH

Salvador Carrillo-Tornel^1*, Tzu Hua Chen-Liang, MD PhD^2*, Ana Yeguas Bermejo^3*, Helena Pomares, PhD^4*, Alessandro Liquori, PhD^5*, Teresa González^6*, Teresa Bernal del Castillo^7*, Marta Santiago^8*, Félix López Cadenas, MD^9*, Bernardo López Andrade, MD^10*, Raul Teruel Montoya, PhD^11*, Esperanza Such, PhD^12*, Francisca Maria Hernandez, DM^13*, Blanca Xicoy, MD^14*, Montserrat Arnan Sangerman, PhD^15*, Francesc Solé, PhD¹⁶, Jose Cervera, MD, PhD^17*, Maria Diez-Campelo, MD^18* and Andres Jerez, MD, PhD^19*

¹Hospital Morales Meseguer,CRH-IMIB, Murcia, MURCIA, Spain
²Hospital Morales Meseguer. CRH-IMIB, Murcia, Spain
³Hematology Department, Hospital Universitario de Salamanca, IBSAL, Salamanca, Spain
⁴Clinical Hematology Department, Institut Català d'Oncologia, Hospital Duran i Reynals, IDIBELL, L’Hospitalet de Llobregat, Barcelona, Spain, L’Hospitalet de Llobregat, Barcelona, Spain
⁵Servicio de Hematología. Hospital La Fe, Valencia, Spain, Valencia, Spain
⁶Molecular Genetics in Oncohematology, Institute of Biomedical Research of Salamanca (IBSAL) - Cancer Research Center of Salamanca (USAL-CSIC), Salamanca, Spain
⁷Hospital Universitario Central Asturias, Oviedo, Spain
⁸Hospital Universitario y Politecnico La Fe, CIBERONC, Valencia, Valencia, Spain
⁹Hematology Department, Hospital Universitario de Salamanca-IBSAL, Salamanca, Spain
¹⁰Hematology Department, Son Espases University Hospital, IdISBa, Palma Mallorca, Spain
¹¹Servicio de Hematología y Oncología Médica. H.U. Morales Meseguer. Centro Regional de Hemodonación. Universidad de Murcia. IMIB-Arrixaca, Murcia, Spain
¹²Hematology Department., Hospital Universitario y Politécnico La Fe, Valencia, Spain
¹³Hospital Virgen de las Nieves, Granada, Salobreña, Granada, Spain
¹⁴Hematology Department, Institut Català d’Oncologia-Hospital Germans Trias i Pujol, Josep Carreras Leukemia Research Institute, Universitat Autònoma de Barcelona, Badalona, Spain
¹⁵Hematology Department. Institut Català d'Oncologia, Hospital Duran i Reynals. Institut d’Investigació Biomèdica de Bellvitge (IDIBELL). Universitat de Barcelona, L'Hospitalet de Llobregat. Barcelona, Spain
¹⁶Josep Carreras Leukemia Research Institute (IJC), ICO-Hospital GermansTrias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain
¹⁷Department of Hematology and Genetics Unit, Hospital Universitario La Fe, Valencia, Va, Spain
¹⁸Department of Hematology. Salamanca-IBSAL university hospital, Salamanca, salamanca, Spain
¹⁹Hematology and Medical Oncology Department, Hospital Morales Meseguer, IMIB-CRH, MURCIA, Spain

Hanny Al-Samkari, MD¹, Pierre Fenaux², Mikkael A. Sekeres, MD³, Eytan Stein, MD⁴, David A. Sallman, MD⁵, Andrew M. Brunner, MD¹, Xiaoshu D. Gurov, PhD^6*, Ophelia Yin, PhD^6*, Meghan Frisbie, BA^6*, James Xiao, PhD^6*, Joy Bhatia, MD^6*, Vanessa Beynon, MD^6*, Megan Wind-Rotolo, PhD^6*, Melissa Dibacco, MD^6* and Uwe Platzbecker, MD⁷

¹Division of Hematology/Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA
²Service d’Hématologie Séniors, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France
³University of Miami, Sylvester Comprehensive Cancer Center, Miami, FL
⁴Division of Hematologic Oncology, Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY
⁵Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL
⁶Agios Pharmaceuticals, Inc., Cambridge, MA
⁷Medical Clinic and Policlinic 1, Hematology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany

Valeria Santini, MD, PhD^1*, Pierre Fenaux², Amer M. Zeidan, MD³, Rami S. Komrokji⁴, Rena Buckstein⁵, Esther Natalie Oliva, MD⁶, Xianwei Ha^7*, Dimana Miteva^8*, Aylin Yucel, PhD^7*, Jose Alberto Nadal^8* and Uwe Platzbecker, MD⁹

¹University of Florence, Florence, Italy
²Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France
³Yale School of Medicine and Yale Cancer Center, Yale University, New Haven, CT
⁴Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL
⁵Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
⁶Grande Ospedale Metropolitano Bianchi Melacrino Morelli, Reggio Calabria, Italy
⁷Bristol Myers Squibb, Princeton, NJ
⁸Celgene International Sàrl, a Bristol-Myers Squibb Company, Boudry, Switzerland
⁹Department for Hematology, Cell Therapy and Hemostaseology, University of Leipzig Medical Center, Leipzig, Germany

Lucie Freiman^1*, Lise Larcher^2*, Giulia Tueur^2*, Nadia Vasquez^2*, Mélanie Da Costa^2*, Emmanuel Raffoux^3*, Lionel Ades³, Pierre Fenaux⁴, Jean Soulier, MD, PhD², Emmanuelle Clappier^2* and Marie Sebert, MD, PhD^5*

¹Department of Hematology, Université de Paris, Saint-Louis Hospital, PARIS, France
²Hematology Laboratory and INSERM U944, Université de Paris, Saint-Louis Hospital, Paris, France
³Department of Hematology, Université de Paris, Saint-Louis Hospital, Paris, France
⁴Service d'Hématologie Séniors, Hôpital Saint-Louis, Université Paris 7, Paris, France
⁵Department of Clinical Hematology, Hôpital saint louis, Paris, France

Luxi Song, MD^1*, Chunkang Chang, PhD^2* and Jianxiang Wang, MD³

¹Shanghai Jiaotong University Affiliated Sixth People's Hospital, SHANGHAI, China
²Department of Hematology, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China
³State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Blood Diseases Hospital & Institute of Hematology, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China

Adriana Plesa^1,2*, Joris Gutrin, Researcher^3*, Christophe Roumier, PharmD^4,5*, Sandrine Hayette, PhD^6*, Isabelle Tigaud, MD^7*, Sarah Huet, PharmD, PhD^8*, Delphine Manzoni, PharmD^9*, Florent Dumezy, PharmD^10*, Fiorenza Barraco, MD^11*, Herve Ghesquieres, MD, PhD^12*, Claude Preudhomme, PharmD, PhD^4,13, Pierre Sujobert, MD, PhD^14* and Mael Heiblig, MD, PhD^15*

¹Lyon University Hospital, CHU-HCL, Lyon Sud, Pierre Benite, France
²Coordinator of the AML MRDflow & LSC - ALFA French Intergroup, CHU-CHLS-HCL Lyon, France
³Laboratoire D'Hematologie -hopital Lyon-Sud, Pierre Benite, FRA
⁴Laboratory of Hematology, CHU Lille, Lille, France
⁵CHU-Lille, Coordinator of the AML MRDflow & LSC - ALFA French Intergroup, CHU-Lille, France
⁶Centre Hospitalier Lyon Sud, Pierre Benite, FRA
⁷Hospices Civils De Lyon, France, Pierre Benite, FRA
⁸Centre Hospitalier Universitaire de Lyon, Lyon, France
⁹Lyon Sud University Hospital, Pierre Benite, France
¹⁰Laboratory of Hematology, Lille University Hospital, Lille, France
¹¹Clinical hematology service, Hospices Civils de Lyon, Lyon, France
¹²Department of Hematology, Lyon Sud University Hospital/Hospices Civils de Lyon, Pierre Benite, France
¹³ALFA Group, Paris, France
¹⁴Laboratory of Hematology, Centre Hospitalier Lyon Sud, Pierre Bénite, France
¹⁵Department of Hematology, CHLS, Centre Hospitalier Lyon Sud, Pierre Benite, France

Jean M.G. Sabile, MD^1*, Andy Kaempf^2*, Kaitlyn Tomic, MSN, AGPCNP-BC^3*, Gurusidda Manu, MD^4*, Ronan T. Swords, MD^5* and Yazan Migdady, MD, MSc⁴

¹Department of Medicine, Oregon Health and Science University, Portland, OR
²Biostatistics Shared Resource, Knight Cancer Institute, Oregon Health & Science University, Portland, OR
³Oregon Health & Sciences University, Portland, OR
⁴Knight Cancer Institute/ Division of Hematology/Medical Oncology, Oregon Health & Sciences University, Portland, OR
⁵Knight Cancer Institute/ Division of Hematology/Medical Oncology, Oregon Health & Science University, Portland, OR

Ing S Tiong, FRACP, FRCPA, MPhil^1,2, William S Stevenson, MBBS, PhD, FRACP, FRCPA^2,3, Meaghan Wall, MBBS, PhD⁴, Yan Zhuang Yap^5*, John F. Seymour, MBBS, PhD, FRACP^2,6, Melita Kenealy, MBBS, FRACP, FRCPA^2,7,8,9* and Piers Blombery, MBBS^10,11,12

¹Peter MacCallum Cancer Centre and the Royal Melbourne Hospital, Melbourne, VIC, Australia
²Australasian Leukaemia & Lymphoma Group, Richmond, Australia
³Department of Haematology, Royal North Shore Hospital, Sydney, NSW, Australia
⁴Victorian Clinical Genetics Services, Murdoch Children's Research Institute, Melbourne, Australia
⁵Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia
⁶Peter MacCallum Cancer Centre, Royal Melbourne Hospital, University of Melbourne, Melbourne, VIC, Australia
⁷Cabrini Hospital, Melbourne, Australia
⁸Monash University, Melbourne, Australia
⁹University of Melbourne, Melbourne, Australia
¹⁰Peter MacCallum Cancer Centre, Peter Maccallum Cancer Centre, East Melbourne, VIC, Australia
¹¹Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia
¹²Australasian Leukaemia & Lymphoma Group, Richmond, VIC, Australia

Junying Wu^1*, Yudi Zhang, PhD^1*, Tiejun Qin^2*, Zefeng Xu^1,2*, Shiqiang Qu^1,2*, Lijuan Pan^2*, Bing Li^1,2*, Qingyan Gao^1,2*, Robert Peter Gale³ and Zhijian Xiao, MD&PhD^2,4,5*

¹State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
²MDS and MPN Centre, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
³Centre for Haematology Research, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom
⁴State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
⁵Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China

Christina Misidou^1*, Eleni Gkolia^2*, Chrysa Kymparidou^1*, Vasileios Papadopoulos^1*, Menelaos Konstantinos Papoutselis^1*, Konstantinos Liapis, MD, PhD^3*, George Vrachiolias^1*, Savvas Deftereos^2*, Dimitrios Stakos^4* and Ioannis Kotsianidis, MD, PhD³

¹Department of Hematology, Democritus University of Thrace Medical School, Alexandroupolis, Greece
²Department of Radiology, University General Hospital of Alexandroupolis, Alexandroupolis, Greece
³Department of Hematology, Democritus University of Thrace Medical School, University Hospital of Alexandroupolis, Alexandroupolis, Greece
⁴Cardiology Department, Democritus University of Thrace, Alexandroupolis, Greece

Sofia Grille, MD, PhD¹, Elvira DRP Velloso, MD, PhD^2*, Matilde Boada, MD. MSc^3*, Elia Apodaca Chavez^4*, Andres Gomez-De Leon, MD⁵, Anna Cecilia Rodríguez-Zuñiga, MD^6*, Emmanuel Martínez Moreno, MD^7*, Fernando Perez-Jacobo, MD^8*, Graciela Alfonso, MD^9*, Juan Carlos Serrano, MD^10*, Natalia Tejeira, MD^11*, Lilián Díaz, MD^12*, Valentina Olivares, MD^12*, Laura Kornblihtt, PhD^13*, Sergio Schusterschitz, MD^14* and Marcelo Iastrebner, MD^15*

¹Catedra de Hematologia, Hospital de Clínicas. Facultad de Medicina. Universidad de la Republica, Montevido, Uruguay
²Department of Hematology, Federal University of Ceará, Fortaleza, Brazil
³Cátedra de Hematología, Hospital de Clinicas Dr Manuel Quintela, Montevideo, Uruguay
⁴Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico
⁵Servicio de Hematología, Universidad Autonoma de Nuevo Leon, Hospital Universitario "Dr. José Eleuterio Gonzalez", Monterrey, Mexico
⁶Hematology, Universidad Autónoma de Nuevo León, Facultad de Medicina y Hospital Universitario Dr José Eleuterio González, Monterrey, Mexico
⁷Hospital General de México Dr. Eduardo Liceaga., Ciudad de México., Mexico
⁸Hematology and blood bank services, Hospital Central Norte PEMEX, CDMX, Mexico
⁹Hospital Nacional Prof. Alejandro Posadas., Buenos Aires, Argentina
¹⁰Unidad Hematológica Especializada, Cucuta, Colombia
¹¹Cooperativa Médica de Flores. COMEFLO., Florida, Uruguay
¹²Servicio Medico Integral. SMI, Montevideo, Uruguay
¹³Hospital de Clínicas José de San Martín, Buenos Aires, Argentina
¹⁴HC-UFMG, Belo Horizonte, Minas Gerais, Brazil
¹⁵Sanatorio Sagrado Corazón, Ciudad Autónoma de Buenos Aires, Argentina

Jitka Vesela^1*, Hana Votavova, PhD^1*, Monika Kaisrlikova, MSc^1,2*, Zuzana Lenertova^1,2*, David Kundrat^1*, Iva Trsová^1,3*, Sarka Ransdorfova^1*, Dana Mikulenkova, MD^1*, Jaroslav Cermak, MD, PhD⁴ and Monika Belickova, PhD^1*

¹Institute of Hematology and Blood Transfusion, Prague, Czech Republic
²First Faculty of Medicine, Charles University, Prague, Czech Republic
³Faculty of Science, Charles University, Prague, Czech Republic
⁴Institute of Hematology and Blood Transfusion, Praha, Czech Republic