Haotian Zhang¹ and Huichun Zhan, MD^2,3

¹Graduate Program in Molecular & Cellular Biology, Stony Brook University, Stony Brook, NY
²Department of Medicine, Stony Brook School of Medicine, Stony Brook
³Northport VA Medical Center, Northport

Tamara Codilupi^1*, Jakub Szybinski, PhD^1*, Sime Brkic, PhD^1*, Simona Stivala, PhD^1*, Julie Yang, PhD^2*, Nilabh Ghosh, PhD^1*, Katarzyna Buczak, PhD^3*, Jakob Passweg, MD^4*, Anne Angelillo-Scherrer, MD-PhD⁵, Stefan Dirnhofer, MD^6*, Ross L. Levine, MD⁷, Richard Koche, PhD^2,8* and Sara C. Meyer, MD, PhD^1,9

¹Department of Biomedicine, University Hospital Basel and University of Basel, Basel, Switzerland
²Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY
³Proteomics Core Facility Biozentrum, University of Basel, Basel, Switzerland
⁴Division of Hematology, University Hospital Basel, Basel, Switzerland
⁵Department of Hematology and Central Hematology Laboratory, Inselspital, University Hospital and University of Bern, Bern, Switzerland
⁶Department of Pathology, University Hospital Basel, Basel, Switzerland
⁷Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY
⁸Human Oncology and Pathogenesis Program, Leukemia Service, Department of Medicine, Center for Epigenetics, Memorial Sloan Kettering Cancer Center, New York, NY
⁹Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland

Saravanan Ganesan^1*, Sarah Awan-Toor^1*, Fabien Guidez, PhD^2,3*, Nabih Maslah, PharmD, PhD^4,5,6*, Celine Aoun^1*, Panhong Gou, PhD^1*, Chloe Guiguen^1*, Juliette Soret, MD^7*, Odonchimeg Ravdan^8*, Valeria Bisio, PhD^9*, Nicolas Dulphy, PhD^10,11*, Marie-Hélène Schlageter, PharmD, PhD^12*, Michele Souyri, PhD^13*, Stephane Giraudier, MD, PhD^1,4,14*, Jean-Jacques Kiladjian, MD^1,15, Christine Chomienne, MD, PhD^16* and Bruno Cassinat, PharmD, PhD^1,6

¹IRSL, Inserm UMRS 1131, Paris, France
²U1232/LNC Inserm, team Epi2THM, UBFC, Dijon, France
³Inserm UMRS 1131, Paris, FRA
⁴Universite de Paris Cite, Paris, France
⁵IRSL, INSERM UMR 1131, Paris, France
⁶AP-HP, Hopital Saint-Louis, Laboratoire de Biologie Cellulaire, Paris, France
⁷Centre d'Investigations Cliniques, APHP, Hopital Saint-Louis, Paris, France
⁸Service de Biologie Cellulaire, Paris, France
⁹IRSL, Inserm U1160, Paris, FRA
¹⁰AP-HP, Hopital Saint-Louis, Laboratoire d'Immunologie et d'Histocompatibilite, Paris, France
¹¹Université Paris-Cité, Institut de Recherche Saint-Louis, INSERM U1160, Paris, France
¹²Service de Biologie Cellulaire, Hôpital Saint-Louis AP-HP, PARIS, France
¹³Institut de Recherche St Louis, Université de Paris Cite, INSERM U1131, Paris, France
¹⁴AP-HP, Hopital Saint-Louis, Service de Biologie Cellulaire, Paris, France
¹⁵Centre d'Investigations Cliniques (INSERM CIC 1427), AP-HP, Hôpital Saint-Louis, Université Paris Cité, Paris, France
¹⁶Inserm UMR-S1131, Université De Paris, IRSL, HôPital Saint-Louis, Paris, FRA

Bao T. Le^*, Yue Yang, PhD and Golam Mohi, PhD

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA

Bella Banjanin^1,2*, James Nagai^3*, Yevin Mun^4*, Inge Snoeren^1,2*, Stijn Fuchs^1,2*, Marek Weiler^5*, Fabian Kiessling^5*, Twan Lammers^5*, Kishor Sivaraj^6*, Ralf Adams^6*, Cesar Nombela-Arrieta, PhD^7*, Ivan Costa, PhD^3* and Rebekka K. Schneider, MD, PhD^1,2,8

¹Department of Developmental Biology, Erasmus MC, Rotterdam, Netherlands
²Oncode Institute, Erasmus MC, Rotterdam, Netherlands
³Institute for Computational Genomics, Faculty of Medicine, RWTH Aachen University, Aachen, Germany
⁴Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland
⁵Department of Experimental Molecular Imaging, RWTH Aachen University, Aachen, Germany
⁶Max Planck Institute for Molecular Biomedicine, Munster, Germany
⁷Laboratory of Experimental Hematology, Clinics for Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland
⁸Institute for Cell and Tumor Biology, RWTH Aachen University Hospital, Lemiers, Netherlands

Veronika Kropackova^1*, Jan Gursky, PhD^2*, Jana Balounova, PhD^3*, Vladimir Korinek, PhD^1*, Vladimir Divoky, PhD² and Lucie Lanikova, PhD¹

¹Department of Cell and Developmental Biology, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic
²Department of Biology, Faculty of Medicine and Dentistry, Palacký University Olomouc, Olomouc, Czech Republic
³Czech Centre for Phenogenomics & Laboratory of Transgenic Models of Diseases, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic

Tanner H Robison, MS^1*, Manisha Solipuram^2*, Winston Y Lee, MD, PhD^3*, Kathryn Luker^2*, Kristen M. Pettit⁴, Moshe Talpaz, MD⁵, Dariya Malyarenko^2*, Thomas Chenevert^2*, Brian Ross^2* and Gary Luker^2*

¹Biomedical Engineering, University of Michigan, Ann Arbor, MI
²University of Michigan, Ann Arbor, MI
³Department of Pathology, University of Michigan, Ann Arbor, MI
⁴Rogel Cancer Center, The University of Michigan, Ann Arbor, MI
⁵University of Michigan Comprehensive Cancer Center, Ann Arbor, MI

Laura Massarenti^1*, Trine A. Knudsen, MD^2*, Christian Enevold, PhD^1*, Vibe Skov, PhD^2*, Lasse Kjær, PhD^2*, Morten Kranker Larsen, MSc^2,3*, Claus Henrik Nielsen, MD^1* and Hans Carl Hasselbalch, MD²

¹Institute for Inflammation Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
²Department of Hematology, Zealand University Hospital, Roskilde, Denmark
³Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Ryan Yen, BSc^1,2, Lambert Yue, PhD^1*, Steven Pelech, PhD^1,3* and Xiaoyan Jiang, MD, PhD¹

¹Department of Medicine, University of British Columbia, Vancouver, BC, Canada
²Terry Fox Laboratory, BC Cancer Research Institute, Vancouver, BC, Canada
³Kinexus Bioinformatics Corporation, Vancouver, BC, Canada

Danny V Jeyaraju, PhD^1*, Sheida Hayati^2*, Ann Polonskaia^1*, Maryam Alapa^1*, Manuel Ugidos, PhD^3*, Andrew Browne^4*, Alberto Risueño, PhD^5*, Patrick Hagner, PhD^6*, Vikas Gupta, MD, FRCP, FRCPath⁷, Moshe Talpaz, MD⁸, Christopher Hernandez, MSc^9*, Vincent Chia, PhD^9*, Patricia Martin-Regueira, MD^9,10*, Daniel Lopes de Menezes, PhD^9*, Ross La Motte-Mohs^11*, Rajasekhar NVS Suragani^4* and Anita K. Gandhi, PhD⁶

¹Translational Development and Diagnostics, Bristol Myers Squibb, Summit, NJ
²Bristol Myers Squibb, Princeton
³BMS Center for Innovation and Translational Research Europe (CITRE), a Bristol-Myers Squibb Company, Seville, Spain
⁴Bristol Myers Squibb, Cambridge, MA
⁵Centre for Innovation and Translational Research Europe, A Bristol Myers Squibb Company, Seville, Spain
⁶Translational Medicine Hematology, Bristol Myers Squibb, Summit, NJ
⁷Division of Medical Oncology and Hematology, University Health Network, Toronto, ON, Canada
⁸University of Michigan Comprehensive Cancer Center, Ann Arbor, MI
⁹Bristol Myers Squibb, Princeton, NJ
¹⁰Bristol Myers Squibb, Madrid, Spain
¹¹Translational Development & Diagnostics, Bristol Myers Squibb, Summit, NJ

Srdan Verstovsek, MD, PhD¹, John Mascarenhas, MD², Raajit K Rampal, MD, PhD³, Daniela Cilloni, MD^4*, Claire N. Harrison, DM⁵, Brian Jacoby, MD, MBA^6*, Robert J. Slack, PhD, FRSB^7*, Vassilios Aslanis, MSc, PhD^8*, Bobby Singh, MBBS, APGDPM^9* and Bertil Lindmark, MD, PhD^8*

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Icahn School of Medicine at Mount Sinai, New York, NY
³Department of Medicine, Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY
⁴University Hospital San Luigi Gonzaga, Orbassano, Italy
⁵Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom
⁶Galecto Inc, Copenhagen, Denmark
⁷Galecto, Inc., London, United Kingdom
⁸Galecto, Copenhagen, Denmark
⁹Galecto, Kuala Lumpur, Malaysia

Yücel Erbilgin^1*, Christophe Desterke, PhD^2*, Annelise Bennaceur Griscelli, MD, PhD^3* and Ali G Turhan, MD, PhD⁴

¹Inserm U1310, Villejuif, France
²Inserm U1310, University Paris Saclay, Villejuif, FRA
³Inserm UMS 45, CITHERA Center for iPSC Therapies, Evry, France
⁴INSERM U1310, Villejuif, France

C. Matthias Wilk, MD^1*, Jessica LeBerichel, B.S.^1*, Flurin Cathomas, MD^2*, George Heaton, PhD^3*, Orsolya Török, MD, PhD^4*, Aymeric Silvin, PhD^5*, Zhenyu Yue, PhD^3*, Scott Russo, PhD^2*, Florent Ginhoux, PhD^5,6*, Jennifer Picarsic, MD^7*, Carl E. Allen, MD, PhD⁸ and Miriam Merad, MD, PhD^1,9*

¹Icahn School of Medicine at Mount Sinai, Tisch Cancer Institute, Precision Immunology Institute, New York, NY
²Icahn School of Medicine at Mount Sinai, Nash Family Department of Neuroscience, Brain & Body Research Center, Friedman Brain Institute, New York, NY
³Icahn School of Medicine at Mount Sinai, Friedman Brain Institute, New York, NY
⁴University of Pécs, Medical School, Department of Neurology, Pécs,, Hungary
⁵Inserm U1015, Gustave Roussy Cancer Campus, Villejuif, France
⁶Singapore Immunology Network, Singapore, SGP
⁷University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh O, Pittsburgh, PA
⁸Division of Pediatric Hematology and Oncology, Baylor College of Medicine, Houston, TX
⁹Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY

Shaowei Qiu, MD^1,2*, Vipul Sheth^1*, Chengcheng Yan, MD^1*, Juan Liu^3*, Balu K. Chacko^4*, Hui Li, BS^1*, David Crossman^5*, Seth D. Fortmann^6,7*, Sajesan Aryal, BS¹, Maria B. Grant^6*, Robert S. Welner, PhD^1*, Andrew J. Paterson, PhD^1*, Adam R. Wende^4*, Victor M Darley-Usmar, PhD^4*, Rui Lu, PhD⁸, Jason W. Locasale^3* and Ravi Bhatia, MD⁹

¹Division of Hematology/Oncology, University of Alabama At Birmingham, Birmingham, AL
²State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
³Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC
⁴Department of Pathology, Mitochondrial Medicine Laboratory, University of Alabama at Birmingham, Birmingham, AL
⁵Genomics Core Facility, University of Alabama at Birmingham, Birmingham, AL
⁶Department of Ophthalmology and Visual Sciences, University of Alabama at Birmingham, Birmingham, AL
⁷Medical Scientist Training Program (MSTP), School of Medicine, University of Alabama at Birmingham, Birmingham, AL
⁸Division of Hematology and Oncology, Department of Medicine, University of Alabama At Birmingham, Birmingham, AL
⁹Division of Hematology and Oncology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL

Melissa Lock^1*, Damien Luque Paz^1*, Nils Hansen^1*, Tiago Almeida Fonseca^1*, MARC Usart^2*, Shivam Rai^1*, Hui Hao-Shen^1*, Gabriele Mild^1*, Stephan Dirnhofer^3*, Radek C. Skoda¹ and Jan Stetka^1*

¹Department of Biomedicine, Experimental Hematology, University Hospital Basel and University of Basel, Basel, Switzerland
²Department of Biomedicine, Experimental Hematology, University Hospital Basel and University of Basel, BASEL, Switzerland
³Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland

Nicolas Papadopoulos^1,2,3*, Ajda Pristavec^1*, Gabriel Levy, MD^1,2,3*, Audrey Nédélec, PhD^1,2,3*, Judith Staerk, PhD^4* and Stefan N. Constantinescu, MD, PhD^1,2,3,5

¹de Duve Institute, Université Catholique de Louvain, Brussels, Belgium
²WELBIO (Wallon Excellence in Life Sciences and Biotechnology), Brussels, Belgium
³Ludwig Institute for Cancer Research, Brussels, Belgium
⁴University of Oslo, Oslo, NOR
⁵Oxford University, Nuffield Department of Medicine, Ludwig Institute for Cancer Research, Oxford, United Kingdom